HypertensionNCT06997445
Jacobson's Progressive Muscle Relaxation Technique With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals
A study testing Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercise and Aerobic Exercise in people with Hypertension, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
The study is a randomized controlled trial. The purpose of study is to compare the additive effects of Jacobson's progressive muscle relaxation technique with aerobic exercise versus aerobic exercise on cardiopulmonary parameters including systolic and diastolic blood pressure, heart rate, respiratory rate, rate… Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Hypertension
- What is being tested?
- Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercise and Aerobic Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 sitePakistan
- Study dates
- 2 Aug 2024to 5 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults: aged (18-45 years)
- Gender: both male and female
- Patients diagnosed with stage 1 hypertension (130-139 / 80-89 mmHg according to AHA/ACC 2017 guidelines
- Mild to moderate physical activity level on IPAQ Questionnaire
- Individuals who are able to understand and follow the instructions for exercise
Who cannot join
- Unstable angina, MI, heart failure, advanced CAD patients
- Severe neurological, musculoskeletal, or gynaecological conditions which limit participation in study
- Recent history of fracture
- Morbidly obese (BMI > 40.0 kg / m2)
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Foundation University College of Physical Therapy, Islamabad, 44000
Islamabad, 44000
About this study
Official title: Additive Effects of Jacobson's Progressive Muscle Relaxation Technique With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals
The study is a randomized controlled trial. The purpose of study is to compare the additive effects of Jacobson's progressive muscle relaxation technique with aerobic exercise versus aerobic exercise on cardiopulmonary parameters including systolic and diastolic blood pressure, heart rate, respiratory rate, rate pressure product and quality of life in stage 1 hypertensive individuals.
Read the detailed description
The study will consist of referred stage 1 hypertensive patients by medical specialist/cardiologist.
Participants will be screened through PAR-Q and IPAQ Questionnaire. Cardiac monitor will be used for assessing the cardiopulmonary parameters. SF-36 Questionnaire will be used for assessing the quality of life. Informed written consent will be taken after which participants will be recruited into two groups.
Control group will be provided aerobic exercise while interventional group will be provided Jacobson's progressive muscle relaxation technique with aerobic exercise.
Outcome measures assessment will be done at pre-session, at 2 weeks and after 4 weeks post-intervention
- Conditions
- Hypertension
- Being tested
- Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercise, Aerobic Exercise
- Keywords
- aerobic exercise, quality of life, hypertension, Muscle Relaxation
- Medical subject headings
- Hypertension
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exerciseOther
Jacobaon's progressive muscle relaxation technique for 15 minutes Total duration: 45 minutes
Aerobic ExerciseOther
Participants in this group will only be provided aerobic exercise for 4 weeks supervised by physiotherapist.
Aerobic Exercise include the following:
- Warm up exercises for 5 minutes.
- Brisk walking on treadmill for 25 minutes which include warm up period for 10 minutes then 14 minutes brisk walk and cool down period included 1 minute walk.
- Stepper for 5 minutes.
- Static cycling for 5 minutes.
- Cool down for 5 minutes.
Week 03 and Week 04:
Frequency: 5 days per week Intensity: 60-80% Target heart rate Time: 45 minutes
Week 01 and Week 02:
Frequency: 5 days per week Intensity: 50-60 % Target heart rate Time: 45 minutes
| Study group | Role | What they receive |
|---|---|---|
| Interventional group | Active comparator | Patients in interventional group will receive Jacobson's progressive muscle relaxation technique for 15 minutes and aerobic exercise for 30 minutes.
For Jacobson's progressive muscle relaxation technique first patient is asked to clench each fist separately, fee the tension, release the fist and relax. Then bend each arm separately, feel the tension and then release the arm. Then straighten the arm separately, feel the tension and then relax. Then wrinkle the forehead, feel the tension and then release the eyebrows relax. Then close the eyes and screw the muscles around the eyes and then release. Then tense the jaw by biting the teeth together and relax. Then press the tongue hard and flat against roof of mouth, feel the tension and then relax. Then push the head back and then bring head back to position. Then bring the head down and then relax. Then shrug the shoulders and relax. Then take a deep breath, hold and then relax. Then tense the stomach muscle and then release. Then arch Receives: Other: Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercise |
| Control group | Other | The control group will receive only aerobic exercise for 45 minutes. Aerobic exercise will include warm uo exercises for 5 minutes, brisk walking on treadmill for 25 minutes which include warm up period for 10 minutes then 14 minutes brisk walk and cool down period included 1 minute walk, stepper for 5 minutes, static cycling for 5 minutes and cool down for 5 minutes.
Total 4 weeks protocol. Before and after 4 weeks, pre and post intervention values will be taken.
A total of 20 sessions five days per week for 4 weeks will be provided supervised by physiotherapist Receives: Other: Aerobic Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Systolic and diastolic blood pressure
Evaluation will be done using cardiac monitor for blood pressure.
Measured: 04 Weeks
Heart rate
It will be measured through pulse oximeter.
Measured: 04 Weeks
Respiratory rate
It will be measured by counting the number of breaths a person takes per minute
Measured: 04 Weeks
Rate pressure product
It will be calculated by multiplying heart rate with systolic blood pressure
Measured: 04 Weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 May 2025
- Study start2 Aug 2024
- Primary completion5 Jun 2025
- Study completion5 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HypertensionStudies of the same condition, open and under way.
- More trials run by Foundation University IslamabadThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06997445
- Sponsor's protocol ID
- FUI/CTR/2024/71
- Status last verified
- Sep 2025
- First submitted
- 14 May 2025
- Last updated
- 15 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Additive Effects of Jacobson's Progressive Muscle Relaxation Technique With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals
- ClinicalTrials.gov ID
- NCT06997445
- Acronym / sponsor ID
- FUI/CTR/2024/71
- Conditions
- Hypertension
- Keywords
- aerobic exercise, quality of life, hypertension, Muscle Relaxation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 2 Aug 2024 (actual)
- Primary completion
- 5 Jun 2025 (actual)
- Study completion
- 5 Jun 2025 (actual)
- First posted
- 30 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study is a randomized controlled trial. The purpose of study is to compare the additive effects of Jacobson's progressive muscle relaxation technique with aerobic exercise versus aerobic exercise on cardiopulmonary parameters including systolic and diastolic blood pressure, heart rate, respiratory rate, rate pressure product and quality of life in stage 1 hypertensive individuals.
Detailed description
The study will consist of referred stage 1 hypertensive patients by medical specialist/cardiologist.
Participants will be screened through PAR-Q and IPAQ Questionnaire. Cardiac monitor will be used for assessing the cardiopulmonary parameters. SF-36 Questionnaire will be used for assessing the quality of life. Informed written consent will be taken after which participants will be recruited into two groups.
Control group will be provided aerobic exercise while interventional group will be provided Jacobson's progressive muscle relaxation technique with aerobic exercise.
Outcome measures assessment will be done at pre-session, at 2 weeks and after 4 weeks post-intervention
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Interventional group | Active comparator | Other: Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercisePatients in interventional group will receive Jacobson's progressive muscle relaxation technique for 15 minutes and aerobic exercise for 30 minutes. For Jacobson's progressive muscle relaxation technique first patient is asked to clench each fist separately, fee the tension, release the fist and relax. Then bend each arm separately, feel the tension and then release the arm. Then straighten the arm separately, feel the tension and then relax. Then wrinkle the forehead, feel the tension and then release the eyebrows relax. Then close the eyes and screw the muscles around the eyes and then release. Then tense the jaw by biting the teeth together and relax. Then press the tongue hard and flat against roof of mouth, feel the tension and then relax. Then push the head back and then bring head back to position. Then bring the head down and then relax. Then shrug the shoulders and relax. Then take a deep breath, hold and then relax. Then tense the stomach muscle and then release. Then arch |
| Control group | Other | Other: Aerobic ExerciseThe control group will receive only aerobic exercise for 45 minutes. Aerobic exercise will include warm uo exercises for 5 minutes, brisk walking on treadmill for 25 minutes which include warm up period for 10 minutes then 14 minutes brisk walk and cool down period included 1 minute walk, stepper for 5 minutes, static cycling for 5 minutes and cool down for 5 minutes. Total 4 weeks protocol. Before and after 4 weeks, pre and post intervention values will be taken. A total of 20 sessions five days per week for 4 weeks will be provided supervised by physiotherapist |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Adults: aged (18-45 years)
- Gender: both male and female
- Patients diagnosed with stage 1 hypertension (130-139 / 80-89 mmHg according to AHA/ACC 2017 guidelines
- Mild to moderate physical activity level on IPAQ Questionnaire
- Individuals who are able to understand and follow the instructions for exercise
Key exclusion criteria (4 listed)
- Unstable angina, MI, heart failure, advanced CAD patients
- Severe neurological, musculoskeletal, or gynaecological conditions which limit participation in study
- Recent history of fracture
- Morbidly obese (BMI > 40.0 kg / m2)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exerciseJacobaon's progressive muscle relaxation technique for 15 minutes Total duration: 45 minutes | Other | Interventional group |
| Aerobic ExerciseParticipants in this group will only be provided aerobic exercise for 4 weeks supervised by physiotherapist. Aerobic Exercise include the following: * Warm up exercises for 5 minutes. * Brisk walking on treadmill for 25 minutes which include warm up period for 10 minutes then 14 minutes brisk walk and cool down period included 1 minute walk. * Stepper for 5 minutes. * Static cycling for 5 minutes. * Cool down for 5 minutes. Week 03 and Week 04: Frequency: 5 days per week Intensity: 60-80% Target heart rate Time: 45 minutes Week 01 and Week 02: Frequency: 5 days per week Intensity: 50-60 % Target heart rate Time: 45 minutes | Other | Control group |
Primary outcome
Systolic and diastolic blood pressure
Time frame: 04 Weeks
Evaluation will be done using cardiac monitor for blood pressure.
Heart rate
Time frame: 04 Weeks
It will be measured through pulse oximeter.
Respiratory rate
Time frame: 04 Weeks
It will be measured by counting the number of breaths a person takes per minute
Rate pressure product
Time frame: 04 Weeks
It will be calculated by multiplying heart rate with systolic blood pressure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Interventional group: Jacobson's progressive muscle relaxation technique with aerobic exercise and Aerobic Exercise in people with Hypertension, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Systolic and diastolic blood pressure (time frame: 04 Weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Sep 2025.