Patients Undergoing Arthroscopic Knee SurgeryNCT07002580
Evaluation of the Effectiveness of iPACK and Adductor Canal Blocks on Patients Undergoing Arthroscopic Knee Surgery
A study testing IPACK and adductor canal block with Bupivacaine 0.25% and Spinal Anesthesia with Bupivacaine in people with Patients Undergoing Arthroscopic Knee Surgery, run by Sakarya University at 1 site in Turkey (Türkiye).
Trial summary
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation. Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Patients Undergoing Arthroscopic Knee Surgery
- What is being tested?
- IPACK and adductor canal block with Bupivacaine 0.25% and Spinal Anesthesia with Bupivacaine
- Type of treatment
- Pill or oral medicine, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jul 2025to 1 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients aged between 18 and 50 years,
- Scheduled for arthroscopic knee surgery under spinal anesthesia due to knee pathology
- Patients classified as ASA physical status I-II-III according to the American Society of Anesthesiologists risk classification
Who cannot join
- Coagulopathy
- ASA IV-V patients
- Uncooperable patients
- Patients who refuses to participate in study
- Patients who takes chronic pain treatments
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Sakarya University Training and Research Hospital
Sakarya
Oğuzhan Okumuş, M.D., +905372093019, dr.oguzhanokumusss@gmail.com
Oğuzhan Okumuş, M.D.
About this study
Official title: Evaluation of the Effectiveness of iPACK (Local Anesthetic Infiltration of the Interspace Between the Popliteal Artery and the Posterior Knee Capsule) and Adductor Canal Blocks on Quality of Recovery in Patients Undergoing Arthroscopic Knee Surgery
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation. Inadequate postoperative pain control and poor recovery quality can negatively impact physiotherapy protocols, prolong hospital stays, and consequently lead to cognitive dysfunction, systemic infections, and increased healthcare costs.
Therefore, reducing postoperative pain and improving recovery quality are of great importance. In our clinic, a variety of analgesic techniques are routinely employed as part of a multimodal analgesia approach for patients undergoing arthroscopic knee surgery. One of these techniques is the simultaneous application of the IPACK block and the adductor canal block.
In this study, we aim to evaluate the effectiveness of these blocks on postoperative recovery quality in patients undergoing arthroscopic knee surgery.
- Being tested
- IPACK and adductor canal block with Bupivacaine 0.25%, Spinal Anesthesia with Bupivacaine
- Keywords
- Arthroscopic Knee Surgery, Perifheric Nerve Block, Analgesia, iPACK, Adductor Canal Block, QoR-15
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
IPACK and adductor canal block with Bupivacaine 0.25%Procedure or surgery
iPACK block is infiltration between the Popliteal Artery and the Capsule of the Knee. iPACK and adductor canal blocks are performed with ultrasound guidence under sterile conditions.
Spinal Anesthesia with BupivacaineProcedure or surgery
Spinal Anesthesia is a basic anesthesia method used for years to grant anesthesia for surgeries for lower extremities and lower torso surgeries.
| Study group | Role | What they receive |
|---|---|---|
| Group 1 | Experimental | Group 1 will involve the patients which will be applied iPACK and adductor canal blocks in addition to spinal anesthesia. Receives: Procedure: IPACK and adductor canal block with Bupivacaine 0.25%; Procedure: Spinal Anesthesia with Bupivacaine |
| Group 2 | Experimental | Group 2 will involve the patients which will be applied only spinal anesthesia without additional peripheric nerve blocks. Receives: Procedure: Spinal Anesthesia with Bupivacaine |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quality of Recovery
Quality of Recovery of the patients will be assessed with QoR-15 questionnaire. Its scoring will range between 0 and 150 points.
Measured: 24 hours.
Secondary outcomes (1)
Analgesic Consumption
The total analgesic consumption of patients according to the patient controlled analgesia device which measures the opioid consumption for 24 hours.
Measured: 24 hours.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2025
- Study start1 Jul 2025
- Primary completion1 Jan 2026
- Study completion1 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patients Undergoing Arthroscopic Knee SurgeryStudies of the same condition, open and under way.
- More trials run by Sakarya UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 64 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sakarya University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Oguzhan Okumus, Sakarya University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07002580
- Sponsor's protocol ID
- E-43012747-050.04-463720-202
- Status last verified
- May 2025
- First submitted
- 15 May 2025
- Last updated
- 6 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Effectiveness of iPACK (Local Anesthetic Infiltration of the Interspace Between the Popliteal Artery and the Posterior Knee Capsule) and Adductor Canal Blocks on Quality of Recovery in Patients Undergoing Arthroscopic Knee Surgery
- ClinicalTrials.gov ID
- NCT07002580
- Acronym / sponsor ID
- E-43012747-050.04-463720-202
- Keywords
- Arthroscopic Knee Surgery, Perifheric Nerve Block, Analgesia, iPACK, Adductor Canal Block, QoR-15
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 64 participants (estimated)
- Lead sponsor
- Sakarya UniversityUniversity, hospital or other
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 1 Jan 2026 (actual)
- Study completion
- 1 Apr 2026 (estimated)
- First posted
- 3 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation. Inadequate postoperative pain control and poor recovery quality can negatively impact physiotherapy protocols, prolong hospital stays, and consequently lead to cognitive dysfunction, systemic infections, and increased healthcare costs.
Therefore, reducing postoperative pain and improving recovery quality are of great importance. In our clinic, a variety of analgesic techniques are routinely employed as part of a multimodal analgesia approach for patients undergoing arthroscopic knee surgery. One of these techniques is the simultaneous application of the IPACK block and the adductor canal block.
In this study, we aim to evaluate the effectiveness of these blocks on postoperative recovery quality in patients undergoing arthroscopic knee surgery.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group 1 | Experimental | Procedure: IPACK and adductor canal block with Bupivacaine 0.25%, Procedure: Spinal Anesthesia with BupivacaineGroup 1 will involve the patients which will be applied iPACK and adductor canal blocks in addition to spinal anesthesia. |
| Group 2 | Experimental | Procedure: Spinal Anesthesia with BupivacaineGroup 2 will involve the patients which will be applied only spinal anesthesia without additional peripheric nerve blocks. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Patients aged between 18 and 50 years,
- Scheduled for arthroscopic knee surgery under spinal anesthesia due to knee pathology
- Patients classified as ASA physical status I-II-III according to the American Society of Anesthesiologists risk classification
Key exclusion criteria (5 listed)
- Coagulopathy
- ASA IV-V patients
- Uncooperable patients
- Patients who refuses to participate in study
- Patients who takes chronic pain treatments
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| IPACK and adductor canal block with Bupivacaine 0.25%iPACK block is infiltration between the Popliteal Artery and the Capsule of the Knee. iPACK and adductor canal blocks are performed with ultrasound guidence under sterile conditions. | Procedure or surgery | Group 1 |
| Spinal Anesthesia with BupivacaineSpinal Anesthesia is a basic anesthesia method used for years to grant anesthesia for surgeries for lower extremities and lower torso surgeries. | Procedure or surgery | Group 1, Group 2 |
Primary outcome
Quality of Recovery
Time frame: 24 hours.
Quality of Recovery of the patients will be assessed with QoR-15 questionnaire. Its scoring will range between 0 and 150 points.
1 secondary outcome
Analgesic Consumption
Time frame: 24 hours.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2026.
- Individual participant dataSharing planned: Undecided
Related trials for Patients Undergoing Arthroscopic Knee Surgery
Not yet recruiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
Not yet recruiting
Video-Based Education Versus In-Person Education in Patients Undergoing Arthroscopic Partial Meniscectomy
Partial Meniscectomy, Knee Arthroscopic Surgery
Not yet recruiting
Construction and Application of the Whole Course Management Scheme for Knee Arthroscopic Ligament Surgery Patients Based on "Internet +"
Patients Undergoing Knee Arthroscopic Ligament Surgery
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing IPACK and adductor canal block with Bupivacaine 0.25% and Spinal Anesthesia with Bupivacaine in people with Patients Undergoing Arthroscopic Knee Surgery, run by Sakarya University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Oğuzhan Okumuş, M.D. (+905372093019, dr.oguzhanokumusss@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quality of Recovery (time frame: 24 hours.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.