OverweightHiMod ImpactNCT07008326
Comparing HICT and MICT for Health Improvements in Overweight Young Adults
A study testing High Intensity Circuit Training and Moderate Intensity Continuous Training in people with Overweight, run by Universitas Indonesia at 1 site in Indonesia.
Trial summary
The increasing prevalence of overweight and obesity is becoming a concern worldwide as it is associated with the increased prevalence of non-communicable diseases. One of the main reasons for this problem is that more adults did not fulfill the weekly physical activity recommendations, with the lack of time and… Read more about this study
- Who is it for?
- Ages 18 to 30 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Overweight
- What is being tested?
- High Intensity Circuit Training and Moderate Intensity Continuous Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteIndonesia
- Study dates
- 1 Jun 2025to 30 Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Overweight (BMI 23-24.9 kg/m2)
- Physically inactive in the last 6 months before the study (<150 minutes of moderate-intensity activity and <75 minutes of high-intensity activity)
- Willing to participate in exercise program for 12 weeks
- No other exercise program during the study period
Who cannot join
- Smoking
- Medical comorbidities (diabetes mellitus, hypertension, cardiovascular disease, asthma, dyslipidaemia, epilepsy)
- History of musculoskeletal injuries or health problems related to exercise in the last 1 year
- Dropout Criteria
- Resigning
- Not participating in the endline assessment
- Not participating in the exercise program for 2 consecutive weeks
- Experiencing injury or health problems that led to the inability to participate in the program for 2 consecutive weeks
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Comparative Effects of High-Intensity Circuit Training and Moderate-Intensity Continuous Training on Various Health Parameters in Overweight Young Adults
The increasing prevalence of overweight and obesity is becoming a concern worldwide as it is associated with the increased prevalence of non-communicable diseases. One of the main reasons for this problem is that more adults did not fulfill the weekly physical activity recommendations, with the lack of time and motivation as the main factor. This study aims to compare the effectiveness of a high-intensity circuit training program and the more familiar moderate-intensity continuous training in improving body composition, cardiorespiratory fitness, lipid profile, oxidative stress, and inflammatory markers in young adult males. At the same time, it also explores its adherence through its enjoyment scale and gradual changes in supervision. This experimental study compares pre- and post-tests in the two groups. 3-days food records and 7-days physical activity will be measured monthly as the confounding factors.
Read the detailed description
- Participants will be recruited consecutively via online forms distributed throughout universities and networks across Jakarta and its surrounding area. Interested individuals will go through early screening. Eligible candidates will then complete an initial assessment at the research site.
- Research assistants will use standard operational procedures for each assessment. The training for research assistants will be done before data collection. One group of research assistants are responsible for main outcome data collection. The researcher is responsible for data analysis. Continuous evaluations will be done weekly to improve the research process.
- Sample size is measured from the 6-research outcomes using the sample size calculation formula for evaluating the mean difference between two variables in repeated measurements.
- Eligible candidates who passed the initial assessment will be randomly divided into HICT (intervention) and MICT (control). The 12-week exercise program in both groups will change gradually in volume, intensity, and supervision. Both volume and intensity will be increased according to heart rate targets. Supervision will decrease gradually from fully supervised in the first 4 weeks, partially supervised in the second 4 weeks, and no supervision in the third 4 weeks.
- Data will be collected and electronically recorded during each training session at the research site by the researcher and research assistants. This data includes time, heart rate, blood pressure, rating of perceived exertion (Borg Scale), training intensity, weight used, and enjoyment (PACES).
- Subjects are encouraged to report any problem during intervention via online messaging or during on-site sessions to the research assistants. The reports will be documented in a separate form. The research assistant leading the data collection will ensure that no data is missing by performing daily checking.
- Data collection for the main outcomes will be done by a different group of research assistants and will be masked from the intervention groupings.
- Data analysis will be done using SPSS 26.0 by the researcher. The analysis will be started after baseline measurements are completed. We will present all normally distributed numeric data as mean and standard deviations and non-normally distributed numeric data as median and minimum-maximum range. Bivariate analysis of normally distributed data will be done using repeated 2-way ANOVA test or mixed linear model in case of many dropouts. If data is not distributed normally, the Friedman test will be used. Any missing data will be stated and completed immediately. Close supervision for each subject will be done by research assistance to ensure all necessary reports are collected and analysed.
- Conditions
- Overweight
- Being tested
- High Intensity Circuit Training, Moderate Intensity Continuous Training
- Keywords
- high intensity circuit training, moderate intensity continuous training, overweight, young adult male
- Medical subject headings
- Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High Intensity Circuit TrainingBehavioural
HICT: 3x/week high intensity circuit training for 12 weeks
Moderate Intensity Continuous TrainingBehavioural
3x/week moderate intensity continuous training for 12 weeks
| Study group | Role | What they receive |
|---|---|---|
| High Intensity Circuit Training | Experimental | High Intensity Circuit Training, a bodyweight exercise program performed 3 times per week with increased intensity every 4 weeks Receives: Behavioral: High Intensity Circuit Training |
| Moderate Intensity Continuous Training | Active comparator | Moderate Intensity Continuous Training, brisk walk or jogging based exercise with increased intensity every 2-4 weeks Receives: Behavioral: Moderate Intensity Continuous Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Body Mass Index
Weight and Height will be combined to report Body Mass Index in kg/m^2
Measured: Week 0, 4, 8, 12
Body Fat Percentage
The total percentage of body fat mass measured by BIA Tanita MC-780 in %
Measured: Week 0, 4, 8, 12
Muscle Mass
Muscle mass measured by BIA Tanita MC-780 in kilograms
Measured: Week 0, 4, 8, 12
Visceral Fat Mass
Visceral fat mass measured by BIA Tanita MC-780 in kilograms
Measured: Week 0, 4, 8, 12
Waist Circumference
Waist circumference measured in centimeters
Measured: Week 0, 4, 8, 12
Cardiorespiratory Fitness
VO2Max or VO2peak depends on the feasibility. The cardiac output (mL/min) and body weight (kg) will be combined in mL/kg. min
Measured: Week 0, 12
Total Cholesterol
Total cholesterol in blood measured in mg/dL
Measured: Week 0, 12
High-Density Lipoprotein (HDL)
HDL concentration in blood measured in mg/dL
Measured: Week 0, 12
Low-Density Lipoprotein (LDL)
LDL concentration in blood measured in mg/dL
Measured: Week 0, 12
Triglyceride
Triglyceride concentration in blood measured in mg/dL
Measured: Week 0, 12
Superoxide dismutase
Superoxide dismutase concentration in blood from whole blood sample measured in U/mL
Measured: Week 0, 12
Malondialdehyde
Malondialdehyde concentration in blood from whole blood samples measured in micromolar
Measured: Week 0, 12
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor-alpha concentration in blood measured in pg/mL
Measured: Week 0, 12
Interleukin-6
Interleukin-6 concentration in blood measured in pg/mL
Measured: Week 0, 12
Secondary outcomes (1)
Enjoyment
PACES Score results will be between 18 to 126. A higher score indicates a higher enjoyment level.
Measured: Up to 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Jun 2025
- Study start1 Jun 2025 (estimated)
- Primary completion30 Aug 2025 (estimated)
- Study completion30 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for OverweightStudies of the same condition, open and under way.
- More trials run by Universitas IndonesiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 36 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universitas Indonesia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nani Cahyani Sudarsono, Universitas Indonesia
- Investigators
- Nani C Sudarsono, Doctor, Principal investigator, Fakultas Kedokteran Universitas Indonesia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07008326
- Sponsor's protocol ID
- 24-09-1459
- Acronym
- HiMod Impact
- Status last verified
- Jun 2025
- First submitted
- 25 Apr 2025
- Last updated
- 6 Jun 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Klika B, Jordan C. High-intensity circuit training using body weight: maximum results with minimal investment. ACSM's Health & Fitness Journal. June 2013; 17(3):p 8-13.
Study at a glance
From the registry record, last updated by the sponsor on 6 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of High-Intensity Circuit Training and Moderate-Intensity Continuous Training on Various Health Parameters in Overweight Young Adults
- ClinicalTrials.gov ID
- NCT07008326
- Acronym / sponsor ID
- HiMod Impact / 24-09-1459
- Conditions
- Overweight
- Keywords
- high intensity circuit training, moderate intensity continuous training, overweight, young adult male
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 36 participants (estimated)
- Lead sponsor
- Universitas IndonesiaUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 30 Aug 2025 (estimated)
- Study completion
- 30 Sep 2025 (estimated)
- First posted
- 6 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The increasing prevalence of overweight and obesity is becoming a concern worldwide as it is associated with the increased prevalence of non-communicable diseases. One of the main reasons for this problem is that more adults did not fulfill the weekly physical activity recommendations, with the lack of time and motivation as the main factor. This study aims to compare the effectiveness of a high-intensity circuit training program and the more familiar moderate-intensity continuous training in improving body composition, cardiorespiratory fitness, lipid profile, oxidative stress, and inflammatory markers in young adult males. At the same time, it also explores its adherence through its enjoyment scale and gradual changes in supervision. This experimental study compares pre- and post-tests in the two groups. 3-days food records and 7-days physical activity will be measured monthly as the confounding factors.
Detailed description
- Participants will be recruited consecutively via online forms distributed throughout universities and networks across Jakarta and its surrounding area. Interested individuals will go through early screening. Eligible candidates will then complete an initial assessment at the research site.
- Research assistants will use standard operational procedures for each assessment. The training for research assistants will be done before data collection. One group of research assistants are responsible for main outcome data collection. The researcher is responsible for data analysis. Continuous evaluations will be done weekly to improve the research process.
- Sample size is measured from the 6-research outcomes using the sample size calculation formula for evaluating the mean difference between two variables in repeated measurements.
- Eligible candidates who passed the initial assessment will be randomly divided into HICT (intervention) and MICT (control). The 12-week exercise program in both groups will change gradually in volume, intensity, and supervision. Both volume and intensity will be increased according to heart rate targets. Supervision will decrease gradually from fully supervised in the first 4 weeks, partially supervised in the second 4 weeks, and no supervision in the third 4 weeks.
- Data will be collected and electronically recorded during each training session at the research site by the researcher and research assistants. This data includes time, heart rate, blood pressure, rating of perceived exertion (Borg Scale), training intensity, weight used, and enjoyment (PACES).
- Subjects are encouraged to report any problem during intervention via online messaging or during on-site sessions to the research assistants. The reports will be documented in a separate form. The research assistant leading the data collection will ensure that no data is missing by performing daily checking.
- Data collection for the main outcomes will be done by a different group of research assistants and will be masked from the intervention groupings.
- Data analysis will be done using SPSS 26.0 by the researcher. The analysis will be started after baseline measurements are completed. We will present all normally distributed numeric data as mean and standard deviations and non-normally distributed numeric data as median and minimum-maximum range. Bivariate analysis of normally distributed data will be done using repeated 2-way ANOVA test or mixed linear model in case of many dropouts. If data is not distributed normally, the Friedman test will be used. Any missing data will be stated and completed immediately. Close supervision for each subject will be done by research assistance to ensure all necessary reports are collected and analysed.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| High Intensity Circuit Training | Experimental | Behavioral: High Intensity Circuit TrainingHigh Intensity Circuit Training, a bodyweight exercise program performed 3 times per week with increased intensity every 4 weeks |
| Moderate Intensity Continuous Training | Active comparator | Behavioral: Moderate Intensity Continuous TrainingModerate Intensity Continuous Training, brisk walk or jogging based exercise with increased intensity every 2-4 weeks |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Overweight (BMI 23-24.9 kg/m2)
- Physically inactive in the last 6 months before the study (<150 minutes of moderate-intensity activity and <75 minutes of high-intensity activity)
- Willing to participate in exercise program for 12 weeks
- No other exercise program during the study period
Key exclusion criteria (8 listed)
- Smoking
- Medical comorbidities (diabetes mellitus, hypertension, cardiovascular disease, asthma, dyslipidaemia, epilepsy)
- History of musculoskeletal injuries or health problems related to exercise in the last 1 year
- Dropout Criteria
- Resigning
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High Intensity Circuit TrainingHICT: 3x/week high intensity circuit training for 12 weeks | Behavioural | High Intensity Circuit Training |
| Moderate Intensity Continuous Training3x/week moderate intensity continuous training for 12 weeks | Behavioural | Moderate Intensity Continuous Training |
Primary outcome
Body Mass Index
Time frame: Week 0, 4, 8, 12
Weight and Height will be combined to report Body Mass Index in kg/m^2
Body Fat Percentage
Time frame: Week 0, 4, 8, 12
The total percentage of body fat mass measured by BIA Tanita MC-780 in %
Muscle Mass
Time frame: Week 0, 4, 8, 12
Muscle mass measured by BIA Tanita MC-780 in kilograms
Visceral Fat Mass
Time frame: Week 0, 4, 8, 12
Visceral fat mass measured by BIA Tanita MC-780 in kilograms
Waist Circumference
Time frame: Week 0, 4, 8, 12
Waist circumference measured in centimeters
Cardiorespiratory Fitness
Time frame: Week 0, 12
VO2Max or VO2peak depends on the feasibility. The cardiac output (mL/min) and body weight (kg) will be combined in mL/kg. min
Total Cholesterol
Time frame: Week 0, 12
Total cholesterol in blood measured in mg/dL
High-Density Lipoprotein (HDL)
Time frame: Week 0, 12
HDL concentration in blood measured in mg/dL
Low-Density Lipoprotein (LDL)
Time frame: Week 0, 12
LDL concentration in blood measured in mg/dL
Triglyceride
Time frame: Week 0, 12
Triglyceride concentration in blood measured in mg/dL
Superoxide dismutase
Time frame: Week 0, 12
Superoxide dismutase concentration in blood from whole blood sample measured in U/mL
Malondialdehyde
Time frame: Week 0, 12
Malondialdehyde concentration in blood from whole blood samples measured in micromolar
Tumor Necrosis Factor-alpha
Time frame: Week 0, 12
Tumor Necrosis Factor-alpha concentration in blood measured in pg/mL
Interleukin-6
Time frame: Week 0, 12
Interleukin-6 concentration in blood measured in pg/mL
1 secondary outcome
Enjoyment
Time frame: Up to 12 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Jun 2025.
- BackgroundKlika B, Jordan C. High-intensity circuit training using body weight: maximum results with minimal investment. ACSM's Health & Fitness Journal. June 2013; 17(3):p 8-13.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nani C Sudarsono, Doctor principal investigator
Fakultas Kedokteran Universitas Indonesia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High Intensity Circuit Training and Moderate Intensity Continuous Training in people with Overweight, run by Universitas Indonesia at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nani C Sudarsono, Doctor (+62816736605, nani.cahyani@ui.ac.id), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Body Mass Index (time frame: Week 0, 4, 8, 12). The study lists 14 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07008326, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Jun 2025.