Glycemic Index and Glycemic LoadNCT07015814
Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan
A study testing Golden sugarcane jaggery and Dark brown sugarcane jaggery in people with Glycemic Index and Glycemic Load, run by Rehman Medical Institute - RMI at 1 site in Pakistan.
Trial summary
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Glycemic Index and Glycemic Load
- What is being tested?
- Golden sugarcane jaggery and Dark brown sugarcane jaggery
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 sitePakistan
- Study dates
- Jun 2025to Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Inclusion Criteria:Participants should be clinically healthy, as determined by their medical records and verbal history. Only individuals with normal fasting blood glucose levels (70-99 mg/dL) during screening will be eligible -
Exclusion Criteria:1) Participants must not have any chronic disease, not be taking any medications that influence carbohydrate metabolism (such as corticosteroids or metformin), and should be non-smokers and non-alcoholics.
- Pregnant or lactating female participants, as well as any person with gastrointestinal, metabolic, or endocrine disease (e.g., thyroid disease, PCOS, IBD), will be excluded.
- Also, subjects with a history of recent acute illness (within the last 2 weeks) will be deferred.
-
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response.
Read the detailed description
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response. The findings will help identify which types of jaggery have lower glycemic impact, contributing to better dietary choices for glycemic control.
- Conditions
- Glycemic Index and Glycemic Load
- Being tested
- Golden sugarcane jaggery, Dark brown sugarcane jaggery
- Keywords
- glycemic index
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Golden sugarcane jaggeryOther
Participants will consume a standardized portion of jaggery Type A providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period.
Dark brown sugarcane jaggeryOther
Participants will consume a standardized portion of jaggery Type B providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period.
| Study group | Role | What they receive |
|---|---|---|
| Single group (cross over) | Active comparator | Participants will receive all test interventions (2 different varieties of jaggery and a glucose reference) in a randomized sequence with appropriate washout periods between each session. Blood glucose levels will be measured after each test food to determine and compare glycemic index values. Receives: Other: Golden sugarcane jaggery; Other: Dark brown sugarcane jaggery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Glycemic Index (GI) of Different Types of Jaggery
The incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of each type of jaggery, expressed as a percentage of the glucose reference.
Measured: Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session.
Secondary outcomes (1)
Postprandial Blood Glucose Response Curve
Blood glucose levels at each time point following consumption of jaggery types and glucose, to assess the shape and peak of glycemic response.
Measured: Same as primary outcome (0-120 minutes).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2025
- Study startJun 2025 (estimated)
- Primary completionAug 2025 (estimated)
- Study completionSep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Glycemic Index and Glycemic LoadStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Rehman Medical Institute - RMI
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Naseer Ahmed, Rehman Medical Institute - RMI
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07015814
- Sponsor's protocol ID
- GL/GI-NA_1V2
- Status last verified
- Jun 2025
- First submitted
- 3 Jun 2025
- Last updated
- 11 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food Nutr Pap. 1998;66:1-140. No abstract available.
PubMed 9743703International Diabetes Federation. (2021). *IDF Diabetes Atlas* (10th ed.). Brussels, Belgium: IDF.
Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6. doi: 10.1093/ajcn/34.3.362.
PubMed 6259925
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan
- ClinicalTrials.gov ID
- NCT07015814
- Acronym / sponsor ID
- GL/GI-NA_1V2
- Conditions
- Glycemic Index and Glycemic Load
- Keywords
- glycemic index
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Rehman Medical Institute - RMIUniversity, hospital or other
- Study start
- Jun 2025 (estimated)
- Primary completion
- Aug 2025 (estimated)
- Study completion
- Sep 2025 (estimated)
- First posted
- 11 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response.
Detailed description
This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response. The findings will help identify which types of jaggery have lower glycemic impact, contributing to better dietary choices for glycemic control.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Single group (cross over) | Active comparator | Other: Golden sugarcane jaggery, Other: Dark brown sugarcane jaggeryParticipants will receive all test interventions (2 different varieties of jaggery and a glucose reference) in a randomized sequence with appropriate washout periods between each session. Blood glucose levels will be measured after each test food to determine and compare glycemic index values. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Golden sugarcane jaggeryParticipants will consume a standardized portion of jaggery Type A providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period. | Other | Single group (cross over) |
| Dark brown sugarcane jaggeryParticipants will consume a standardized portion of jaggery Type B providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period. | Other | Single group (cross over) |
Primary outcome
Glycemic Index (GI) of Different Types of Jaggery
Time frame: Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session.
The incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of each type of jaggery, expressed as a percentage of the glucose reference.
1 secondary outcome
Postprandial Blood Glucose Response Curve
Time frame: Same as primary outcome (0-120 minutes).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2025.
- Background: PubMed 9743703Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food Nutr Pap. 1998;66:1-140. No abstract available.
- BackgroundInternational Diabetes Federation. (2021). *IDF Diabetes Atlas* (10th ed.). Brussels, Belgium: IDF.
- Background: PubMed 6259925Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6. doi: 10.1093/ajcn/34.3.362.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Golden sugarcane jaggery and Dark brown sugarcane jaggery in people with Glycemic Index and Glycemic Load, run by Rehman Medical Institute - RMI at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 11 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Naseer Ahmed (03305485960, dr.naseer99@mail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Glycemic Index (GI) of Different Types of Jaggery (time frame: Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07015814, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2025.