Anorexia NervosaNCT07016347
GDF15 in Anorexia Nervosa
An observational study of Anorexia Nervosa, run by Karolinska Institutet at 1 site in Sweden.
Trial summary
Evaluating plasma levels of a protein called GDF15 in active and recovered anorexia nervosa, as well as healthy controls Read more about this study
- Who is it for?
- Ages 18 years and older, women only
- Conditions the study is for
- Anorexia Nervosa
- How many people
- 200 participants
- Where
- 1 siteSweden
- Study dates
- 23 Jan 2017to 4 Nov 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Study population: swedish population
Who may be able to join
- active DSMV diagnosis of anorexia nervosa/ at least two years of recovery from DSMV anorexia nervosa / no history of anorexia nervosa
Who cannot join
- male
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Elevated Plasma GDF15 Combined With FGF21 Suggests Mitochondrial Dysfunction in a Subgroup of Anorexia Nervosa Patients
Evaluating plasma levels of a protein called GDF15 in active and recovered anorexia nervosa, as well as healthy controls
- Conditions
- Anorexia Nervosa
- Medical subject headings
- Anorexia Nervosa
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| active anorexia nervosa | Not described | |
| recovered anorexia nervosa | Not described | |
| healthy controls | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
plasma GDF15
Measured: At baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2025
- Study start23 Jan 2017
- Primary completion15 Nov 2021
- Study completion4 Nov 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anorexia NervosaStudies of the same condition, open and under way.
- More trials run by Karolinska InstitutetThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 200 participants (actual)
Sponsor and investigators
- Lead sponsor
- Karolinska Institutet
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ida AK Nilsson, Karolinska Institutet
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07016347
- Sponsor's protocol ID
- GDF15 in AN
- Status last verified
- Mar 2025
- First submitted
- 21 May 2025
- Last updated
- 11 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Elevated Plasma GDF15 Combined With FGF21 Suggests Mitochondrial Dysfunction in a Subgroup of Anorexia Nervosa Patients
- ClinicalTrials.gov ID
- NCT07016347
- Acronym / sponsor ID
- GDF15 in AN
- Conditions
- Anorexia Nervosa
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 200 participants (actual)
- Lead sponsor
- Karolinska InstitutetUniversity, hospital or other
- Study start
- 23 Jan 2017 (actual)
- Primary completion
- 15 Nov 2021 (actual)
- Study completion
- 4 Nov 2024 (actual)
- First posted
- 11 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Evaluating plasma levels of a protein called GDF15 in active and recovered anorexia nervosa, as well as healthy controls
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| active anorexia nervosa | – | – |
| recovered anorexia nervosa | – | – |
| healthy controls | – | – |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- swedish population
Key inclusion criteria (1 listed)
- active DSMV diagnosis of anorexia nervosa/ at least two years of recovery from DSMV anorexia nervosa / no history of anorexia nervosa
Key exclusion criteria (1 listed)
- male
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
plasma GDF15
Time frame: At baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Anorexia Nervosa, run by Karolinska Institutet at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
plasma GDF15 (time frame: At baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2025.