Mild Cognitive Impairment (MCI)NCT07016893

Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals

A study testing Healthy aging interventions in people with Mild Cognitive Impairment (MCI) and Dementia, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

Search all trials

Trial summary

Purpose: The aim of the project is to contribute to the physical, social, and psychological well-being of elderly individuals with cognitive impairment within a multidisciplinary approach framework, and to increase the level of knowledge and awareness about diseases and aging by organizing exercise, art, and education… Read more about this study

Who is it for?: Ages 65 years and older
Conditions the study is for: Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease
What is being tested?: Healthy aging interventions
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 37 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 28 Sep 2024to 30 Nov 2024
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 65 years and older
All sexes
No healthy volunteers
Older adult

Who may be able to join

Being over 65 years of age
Having one of the diagnoses of MCI, dementia, or Alzheimer's by a neurologist or geriatrician
Having less than 27 points on the Mini Mental State Examination (Zhuang et al., 2021).
Being between stages 2-5 on the Global Impairment Scale.

Who cannot join

Having a pulmonary, neurological, musculoskeletal, or rheumatological disease that may prevent exercise
Having balance problems or lower extremity asymmetry at a level that may prevent exercise
Individuals with unstable medical conditions (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.)
Having vision or hearing problems at a level that will prevent participation in workshops

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Balikesir University Cagis Campus 10145 Balikesir
Balıkesir, Balikesir University Cagis Campus, 10145

Other trials in Turkey (Türkiye)

About this study

Official title: Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals With Cognitive Impairment

Scope and Target Group: Cognitive impairment affects daily life activities by impacting cognitive abilities such as memory, attention, and concentration. Mild Cognitive Impairment (MCI), Dementia, and Alzheimer's Disease (AD) are common cognitive impairments in the elderly. Early prevention strategies and intervention measures during this period are crucial. It is known that non-pharmacological interventions, especially in the early stages of MCI, are a window of opportunity that is promising and cost-effective. The primary target audience of this project is elderly individuals diagnosed with MCI, Dementia, and AD. To maximize the impact, some of the planned training sessions included family members of patients.

Method and Expected Results: The project carried out in collaboration with Balıkesir University and Balıkesir Altıeylül Municipality. Various exercise and art workshops organized. Workshop activities conducted for eight weeks and included an Exercise Workshop (music-based exercises, exercise with active video games, clinical Pilates training, cognitive exercise therapy approach, Nordic walking, dance therapy), Skill-Oriented Art Workshop (systemic calligraphy therapy, soap-candle making workshop, culinary arts workshop), and Disease Awareness Studies (disease awareness information and education, the process from diagnosis to acceptance, experiences of patients and relatives, use of daily life technologies, home adjustments against falls, introduction of municipal services for the elderly).

Conditions: Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric Rehabilitation, Elderly (People Aged 65 or More)
Being tested: Healthy aging interventions
Keywords: Mild Cognitive Impairment, dementia, alzheimer's disease, awareness, workshop, art, exercise, elderly health
Medical subject headings: Cognitive Dysfunction, Dementia, Alzheimer Disease, Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Healthy aging interventionsOther
In our study workshop activities conducted for eight weeks and included an Exercise Workshop (Music-Based Exercise Workshop, Exercise Training with Active Video Games (Exergaming), Clinical Pilates Training Workshop, Cognitive Exercise Therapy Approach Workshop, Nordic walking, dance therapy), Skill-Oriented Art Workshop (Systemic Calligraphy Therapy Workshop, soap-candle making workshop, culinary arts workshop), and Disease Awareness Studies (disease awareness information and education, the process from diagnosis to acceptance, experiences of patients and relatives, use of daily life technologies, home adjustments against falls, introduction of municipal services for the elderly).

Study groups in NCT07016893
Study group	Role	What they receive
Exercise, art, awareness group	Experimental	Mild cognitive impairment (MCI) is an important risk factor for Alzheimer's disease (AD) (Hwang and Lee, 2017). The literature emphasizes that the prevalence of MCI and AD will continue to increase and draws attention to this area (Realdon et al., 2016). The MCI stage, which is the most active part of AD, provides a "window of opportunity" for the prevention and treatment of AD (Wu, 2020). Early prevention strategies are considered important, especially during this period. Improving the individual's cognitive functions and reducing symptoms in the MCI stage will reduce the incidence of AD, thereby reducing healthcare costs and improving the individual's condition and quality of life (Jak, 2012). Since AD is irreversible and faces significant treatment challenges, the key to preventing and treating the disease is to take early prevention and intervention measures (Zhang et al., 2021). When considering these interventions, focus is placed on potentially modifiable risk factors that ma Receives: Other: Healthy aging interventions

What is being measured

The primary outcome is the main question the study is designed to answer.

Mini Mental State Test
It is emphasized in the literature that the Mini Mental State Examination (MMST) is the most frequently used test worldwide for cognitive disorders (Ciesielska et al., 2016). MMST tests orientation, memory, attention, calculation, recall, language, motor function and perception, and visuospatial abilities, and its greatest advantage is that it can be applied easily and quickly (Salis et al., 2023). MMST was used to evaluate cognitive functions in our study. A score between 27-30 on the MMST is considered normal, 24-27 as MCI, 20-23 as mild stage, 10-19 as moderate stage, and 0-9 as advanced stage dementia (Güngen et al., 2002). Individuals with a score of 27 or less on the MMST were included in our study.
Measured: From enrollment to the end of intervention at 8 weeks
Montreal Cognitive Assessment Scale (MoCA)
MoCA is one of the most frequently used tools in clinics to assess cognitive functions and has been translated into 35 languages (Sokolowska et al., 2018). It tests many cognitive domains including short-term memory, visual-spatial skills, executive functions, attention, concentration and working memory, language and orientation. It has been reported that its sensitivity varies between 67-100% and its specificity between 50-95% when evaluated using different cutoffs (Zhuang et al., 2021). The advantage of the test is that it provides a more comprehensive assessment compared to the assessment methods used in the field and is used quite frequently in the elderly population (Breton et al., 2019). MoCA was used in the project to assess the change in cognitive functions of individuals with cognitive impairment.
Measured: From enrollment to the end of intervention at 8 weeks

Secondary outcomes (7)

Muscle Strength Assessment
Handgrip strength is a suitable measurement method for both clinical practice and public health research. Although the measurement of handgrip strength evaluates the function of a muscle group, it can be used to obtain a general idea about the musculoskeletal system in older adults. For this reason, it has been accepted as an indicator of general body strength. In our study, hand dynamometer and pinchmeter devices were used to evaluate the muscle strength of the participants. For the measurement of handgrip strength, participants were asked to sit in a chair with back support and fixed arms and rest their forearms on the arm of the chair so that their wrists were just at the edge of the chair. Measurements were made three times with a hand dynamometer, one minute apart, from the right and left hands, and the average of the results was recorded (Vermeulen et al., 2015).
Measured: From enrollment to the end of intervention at 8 weeks
Flexibility Assessment
Spinal mobility and flexibility are an important component of healthy physical fitness for elderly individuals (Taşpınar et al., 2023). One of the methods frequently used in the literature for flexibility assessment is the sit-and-reach test. The patient is asked to sit with their legs together and their feet on a box, then bend forward as much as possible by extending their arms, without bending their knees, and remaining motionless for 1-2 seconds. The measurement was repeated three times and the average of the farthest distances reached was recorded in cm (Mayorga-Vega et al., 2014).
Measured: From enrollment to the end of intervention at 8 weeks
Physical Activity Level
The short form of the International Physical Activity Questionnaire (IFQQ) was used to determine the physical activity levels of the participants. The IFQQ is a 7-item scale that evaluates the duration and frequency of vigorous physical activity, moderate physical activity, walking and sedentary behavior based on MET values (Craig et al., 2003). The physical activity levels were calculated according to the scores obtained by multiplying the duration, frequency and MET values of the physical activities that the participants participated in for at least 10 minutes within 7 days. The physical activity level assessment was made at the beginning and end of the project, and was repeated three months after the workshops were completed to evaluate sustainability.
Measured: From enrollment to the end of intervention at 8 weeks
Depression Assessment
The Elderly Depression Scale (GDS) is a tool for the diagnosis and assessment of depression in elderly individuals and was developed based on the findings that elderly individuals with depression exhibit unique symptoms such as physical symptoms, anxiety, and decreased cognitive functions (Sheline et al., 2006).
Measured: From enrollment to the end of intervention at 8 weeks
Quality of Life Assessment
Quality of life is a concept related to the individual's perception of his/her situation in life in line with his/her expectations, goals, interests and desires within the culture and social environment he/she lives in, and is defined as the multidimensional evaluation of the individual's person-environment system according to both personal and socio-economic criteria (Stoner et al., 2019). In our study, the 19-item Quality of Life Scale for the Elderly, developed by Hyde et al. (2003), specific to the elderly population, was used.
Measured: From enrollment to the end of intervention at 8 weeks"
Well-Being of Individuals Who Provide Care
Caregiving, which is a multidimensional experience, can cause difficulties as well as positive aspects. In our study, the "Zarit Caregiving Burden Scale" was used to assess the stress experienced by those who provide care to elderly individuals. Studies have reported that the internal consistency coefficient of the scale is between 0.87-0.94 and the test-retest reliability is 0.71. The scale, which can be filled out by the caregivers themselves or the researcher, consists of 22 items that determine the effect of caregiving on the individual's life. The Likert-type scale can also be answered as never, rarely, sometimes, often, or almost always. The minimum score that can be obtained from the scale is 0 and the maximum score is 88. A high scale score indicates that the distress experienced is high.
Measured: From enrollment to the end of intervention at 8 weeks
Satisfaction, Knowledge and Awareness Assessment
At the end of all workshops, patient and caregiver satisfaction, exercise or disease-related knowledge and awareness levels were evaluated by the research team according to the content of the activity. Patients and their relatives were asked to rate their satisfaction level out of 10 after the activities and to answer questions about satisfaction. Below are sample questions that we want the patient to rate as strongly agree (5), agree (4), undecided (3), disagree (2), strongly disagree (1):
- I had a good time and enjoyed the workshop.
- The training of expert staff increased my awareness of methods for combating the disease.
- Workshops increased my social participation.
- I am aware that I need to gain an exercise habit in order to increase my physical activity level.
- Exercise, art and music increase my quality of life and psychological well-being.
Measured: From enrollment to the end of intervention at 8 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

28 Sep 202430 Nov 2024

First posted12 Jun 2025
Study start28 Sep 2024
Primary completion28 Oct 2024
Study completion30 Nov 2024

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (18)Papers the sponsor has linked to this study.
Other trials for Mild Cognitive Impairment (MCI)Studies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Prevention
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 37 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07016893
Sponsor's protocol ID: 2024/112
Status last verified: Jun 2025
First submitted: 3 Jun 2025
Last updated: 12 Jun 2025
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Stoner CR, Orrell M, Spector A. The psychometric properties of the control, autonomy, self-realisation and pleasure scale (CASP-19) for older adults with dementia. Aging Ment Health. 2019 May;23(5):643-649. doi: 10.1080/13607863.2018.1428940. Epub 2018 Jan 22.
PubMed 29356567
Shin C, Park MH, Lee SH, Ko YH, Kim YK, Han KM, Jeong HG, Han C. Usefulness of the 15-item geriatric depression scale (GDS-15) for classifying minor and major depressive disorders among community-dwelling elders. J Affect Disord. 2019 Dec 1;259:370-375. doi: 10.1016/j.jad.2019.08.053. Epub 2019 Aug 20.
PubMed 31470180
Sheline YI, Barch DM, Garcia K, Gersing K, Pieper C, Welsh-Bohmer K, Steffens DC, Doraiswamy PM. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry. 2006 Jul 1;60(1):58-65. doi: 10.1016/j.biopsych.2005.09.019. Epub 2006 Jan 18.
PubMed 16414031
Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003 Aug;35(8):1381-95. doi: 10.1249/01.MSS.0000078924.61453.FB.
PubMed 12900694
Mayorga-Vega D, Merino-Marban R, Viciana J. Criterion-Related Validity of Sit-and-Reach Tests for Estimating Hamstring and Lumbar Extensibility: a Meta-Analysis. J Sports Sci Med. 2014 Jan 20;13(1):1-14. eCollection 2014 Jan.
PubMed 24570599
Taspinar G, Angin E, Oksuz S. The effects of Pilates on pain, functionality, quality of life, flexibility and endurance in lumbar disc herniation. J Comp Eff Res. 2023 Jan;12(1):e220144. doi: 10.2217/cer-2022-0144. Epub 2022 Dec 1.
PubMed 36453667
Vermeulen J, Neyens JC, Spreeuwenberg MD, van Rossum E, Hewson DJ, de Witte LP. Measuring grip strength in older adults: comparing the grip-ball with the Jamar dynamometer. J Geriatr Phys Ther. 2015 Jul-Sep;38(3):148-53. doi: 10.1519/JPT.0000000000000034.
PubMed 25594521
Breton A, Casey D, Arnaoutoglou NA. Cognitive tests for the detection of mild cognitive impairment (MCI), the prodromal stage of dementia: Meta-analysis of diagnostic accuracy studies. Int J Geriatr Psychiatry. 2019 Feb;34(2):233-242. doi: 10.1002/gps.5016. Epub 2018 Nov 27.
PubMed 30370616
Zhuang L, Yang Y, Gao J. Cognitive assessment tools for mild cognitive impairment screening. J Neurol. 2021 May;268(5):1615-1622. doi: 10.1007/s00415-019-09506-7. Epub 2019 Aug 14.
PubMed 31414193
Sokolowska N, Sokolowski R, Polak-Szabela A, Mazur E, Podhorecka M, Kedziora-Kornatowska K. Comparison of the effectiveness of the Montreal Cognitive Assessment 7.2 and the Mini-Mental State Examination in the detection of mild neurocognitive disorder in people over 60 years of age. Preliminary study. Psychiatr Pol. 2018 Oct 27;52(5):843-857. doi: 10.12740/PP/68611. Epub 2018 Oct 27. English, Polish.
PubMed 30584818
Gungen C, Ertan T, Eker E, Yasar R, Engin F. [Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population]. Turk Psikiyatri Derg. 2002 Winter;13(4):273-81. Turkish.
PubMed 12794644
Salis F, Costaggiu D, Mandas A. Mini-Mental State Examination: Optimal Cut-Off Levels for Mild and Severe Cognitive Impairment. Geriatrics (Basel). 2023 Jan 12;8(1):12. doi: 10.3390/geriatrics8010012.
PubMed 36648917
Ciesielska N, Sokolowski R, Mazur E, Podhorecka M, Polak-Szabela A, Kedziora-Kornatowska K. Is the Montreal Cognitive Assessment (MoCA) test better suited than the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI) detection among people aged over 60? Meta-analysis. Psychiatr Pol. 2016 Oct 31;50(5):1039-1052. doi: 10.12740/PP/45368. English, Polish.
PubMed 27992895
Zhang XX, Tian Y, Wang ZT, Ma YH, Tan L, Yu JT. The Epidemiology of Alzheimer's Disease Modifiable Risk Factors and Prevention. J Prev Alzheimers Dis. 2021;8(3):313-321. doi: 10.14283/jpad.2021.15.
PubMed 34101789
Jak AJ. The impact of physical and mental activity on cognitive aging. Curr Top Behav Neurosci. 2012;10:273-91. doi: 10.1007/7854_2011_141.
PubMed 21818703

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

RecruitingPhase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Alzheimer s Disease, Mild Cognitive Impairment
Active, not recruiting
EFFECTS OF AN OUTDOOR MAT PILATES PROGRAM ON NEUROPHYSIOLOGICAL INDICATORS OF ELDERLY INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT
Cognition Disorders
Recruiting
Combating Alzheimer's Through Sleep and Exercise
Dementia, Mild Cognitive Impairment (MCI)
RecruitingPhase 2
Alzheimer's Tau Platform: Master Protocol
Preclinical Alzheimer's Disease, Alzheimer Disease
RecruitingObservational study
Fuzhou Aging Brain Health Initiative
Dementia, Alzheimer Dementia (AD)

All Mild Cognitive Impairment (MCI) trials

Study at a glance

From the registry record, last updated by the sponsor on 12 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals With Cognitive Impairment
ClinicalTrials.gov ID: NCT07016893
Acronym / sponsor ID: 2024/112
Conditions: Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric Rehabilitation, Elderly (People Aged 65 or More)
Keywords: Mild Cognitive Impairment, dementia, alzheimer's disease, awareness, workshop, art, exercise, elderly health
Study type: Interventional
Recruitment status: Completed
Enrolment: 37 participants (actual)
Lead sponsor: Istanbul University - CerrahpasaUniversity, hospital or other
Collaborators: Pamukkale University, The Scientific and Technological Research Council of Turkey
Study start: 28 Sep 2024 (actual)
Primary completion: 28 Oct 2024 (actual)
Study completion: 30 Nov 2024 (actual)
First posted: 12 Jun 2025 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Prevention
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
Exercise, art, awareness group	Experimental	Other: Healthy aging interventionsMild cognitive impairment (MCI) is an important risk factor for Alzheimer's disease (AD) (Hwang and Lee, 2017). The literature emphasizes that the prevalence of MCI and AD will continue to increase and draws attention to this area (Realdon et al., 2016). The MCI stage, which is the most active part of AD, provides a "window of opportunity" for the prevention and treatment of AD (Wu, 2020). Early prevention strategies are considered important, especially during this period. Improving the individual's cognitive functions and reducing symptoms in the MCI stage will reduce the incidence of AD, thereby reducing healthcare costs and improving the individual's condition and quality of life (Jak, 2012). Since AD is irreversible and faces significant treatment challenges, the key to preventing and treating the disease is to take early prevention and intervention measures (Zhang et al., 2021). When considering these interventions, focus is placed on potentially modifiable risk factors that ma

Who may qualify

Ages: 65 years and older
Sex: All
Healthy volunteers: Not accepted
Age groups: Older adult

Key inclusion criteria (4 listed)

Being over 65 years of age
Having one of the diagnoses of MCI, dementia, or Alzheimer's by a neurologist or geriatrician
Having less than 27 points on the Mini Mental State Examination (Zhuang et al., 2021).
Being between stages 2-5 on the Global Impairment Scale.

Key exclusion criteria (4 listed)

Having a pulmonary, neurological, musculoskeletal, or rheumatological disease that may prevent exercise
Having balance problems or lower extremity asymmetry at a level that may prevent exercise
Individuals with unstable medical conditions (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.)
Having vision or hearing problems at a level that will prevent participation in workshops

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Healthy aging interventionsIn our study workshop activities conducted for eight weeks and included an Exercise Workshop (Music-Based Exercise Workshop, Exercise Training with Active Video Games (Exergaming), Clinical Pilates Training Workshop, Cognitive Exercise Therapy Approach Workshop, Nordic walking, dance therapy), Skill-Oriented Art Workshop (Systemic Calligraphy Therapy Workshop, soap-candle making workshop, culinary arts workshop), and Disease Awareness Studies (disease awareness information and education, the process from diagnosis to acceptance, experiences of patients and relatives, use of daily life technologies, home adjustments against falls, introduction of municipal services for the elderly).	Other	Exercise, art, awareness group

Primary outcome

Mini Mental State Test
Time frame: From enrollment to the end of intervention at 8 weeks
It is emphasized in the literature that the Mini Mental State Examination (MMST) is the most frequently used test worldwide for cognitive disorders (Ciesielska et al., 2016). MMST tests orientation, memory, attention, calculation, recall, language, motor function and perception, and visuospatial abilities, and its greatest advantage is that it can be applied easily and quickly (Salis et al., 2023). MMST was used to evaluate cognitive functions in our study. A score between 27-30 on the MMST is considered normal, 24-27 as MCI, 20-23 as mild stage, 10-19 as moderate stage, and 0-9 as advanced stage dementia (Güngen et al., 2002). Individuals with a score of 27 or less on the MMST were included in our study.
Montreal Cognitive Assessment Scale (MoCA)
Time frame: From enrollment to the end of intervention at 8 weeks
MoCA is one of the most frequently used tools in clinics to assess cognitive functions and has been translated into 35 languages (Sokolowska et al., 2018). It tests many cognitive domains including short-term memory, visual-spatial skills, executive functions, attention, concentration and working memory, language and orientation. It has been reported that its sensitivity varies between 67-100% and its specificity between 50-95% when evaluated using different cutoffs (Zhuang et al., 2021). The advantage of the test is that it provides a more comprehensive assessment compared to the assessment methods used in the field and is used quite frequently in the elderly population (Breton et al., 2019). MoCA was used in the project to assess the change in cognitive functions of individuals with cognitive impairment.

7 secondary outcomes

Muscle Strength Assessment
Time frame: From enrollment to the end of intervention at 8 weeks
Flexibility Assessment
Time frame: From enrollment to the end of intervention at 8 weeks
Physical Activity Level
Time frame: From enrollment to the end of intervention at 8 weeks
Depression Assessment
Time frame: From enrollment to the end of intervention at 8 weeks
Quality of Life Assessment
Time frame: From enrollment to the end of intervention at 8 weeks"
Well-Being of Individuals Who Provide Care
Time frame: From enrollment to the end of intervention at 8 weeks
Satisfaction, Knowledge and Awareness Assessment
Time frame: From enrollment to the end of intervention at 8 weeks

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 12 Jun 2025.
Background: PubMed 29356567Stoner CR, Orrell M, Spector A. The psychometric properties of the control, autonomy, self-realisation and pleasure scale (CASP-19) for older adults with dementia. Aging Ment Health. 2019 May;23(5):643-649. doi: 10.1080/13607863.2018.1428940. Epub 2018 Jan 22.
Background: PubMed 31470180Shin C, Park MH, Lee SH, Ko YH, Kim YK, Han KM, Jeong HG, Han C. Usefulness of the 15-item geriatric depression scale (GDS-15) for classifying minor and major depressive disorders among community-dwelling elders. J Affect Disord. 2019 Dec 1;259:370-375. doi: 10.1016/j.jad.2019.08.053. Epub 2019 Aug 20.
Background: PubMed 16414031Sheline YI, Barch DM, Garcia K, Gersing K, Pieper C, Welsh-Bohmer K, Steffens DC, Doraiswamy PM. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry. 2006 Jul 1;60(1):58-65. doi: 10.1016/j.biopsych.2005.09.019. Epub 2006 Jan 18.
Background: PubMed 12900694Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003 Aug;35(8):1381-95. doi: 10.1249/01.MSS.0000078924.61453.FB.
Background: PubMed 24570599Mayorga-Vega D, Merino-Marban R, Viciana J. Criterion-Related Validity of Sit-and-Reach Tests for Estimating Hamstring and Lumbar Extensibility: a Meta-Analysis. J Sports Sci Med. 2014 Jan 20;13(1):1-14. eCollection 2014 Jan.
Background: PubMed 36453667Taspinar G, Angin E, Oksuz S. The effects of Pilates on pain, functionality, quality of life, flexibility and endurance in lumbar disc herniation. J Comp Eff Res. 2023 Jan;12(1):e220144. doi: 10.2217/cer-2022-0144. Epub 2022 Dec 1.
Background: PubMed 25594521Vermeulen J, Neyens JC, Spreeuwenberg MD, van Rossum E, Hewson DJ, de Witte LP. Measuring grip strength in older adults: comparing the grip-ball with the Jamar dynamometer. J Geriatr Phys Ther. 2015 Jul-Sep;38(3):148-53. doi: 10.1519/JPT.0000000000000034.
Background: PubMed 30370616Breton A, Casey D, Arnaoutoglou NA. Cognitive tests for the detection of mild cognitive impairment (MCI), the prodromal stage of dementia: Meta-analysis of diagnostic accuracy studies. Int J Geriatr Psychiatry. 2019 Feb;34(2):233-242. doi: 10.1002/gps.5016. Epub 2018 Nov 27.
Background: PubMed 31414193Zhuang L, Yang Y, Gao J. Cognitive assessment tools for mild cognitive impairment screening. J Neurol. 2021 May;268(5):1615-1622. doi: 10.1007/s00415-019-09506-7. Epub 2019 Aug 14.
Background: PubMed 30584818Sokolowska N, Sokolowski R, Polak-Szabela A, Mazur E, Podhorecka M, Kedziora-Kornatowska K. Comparison of the effectiveness of the Montreal Cognitive Assessment 7.2 and the Mini-Mental State Examination in the detection of mild neurocognitive disorder in people over 60 years of age. Preliminary study. Psychiatr Pol. 2018 Oct 27;52(5):843-857. doi: 10.12740/PP/68611. Epub 2018 Oct 27. English, Polish.
Background: PubMed 12794644Gungen C, Ertan T, Eker E, Yasar R, Engin F. [Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population]. Turk Psikiyatri Derg. 2002 Winter;13(4):273-81. Turkish.
Background: PubMed 36648917Salis F, Costaggiu D, Mandas A. Mini-Mental State Examination: Optimal Cut-Off Levels for Mild and Severe Cognitive Impairment. Geriatrics (Basel). 2023 Jan 12;8(1):12. doi: 10.3390/geriatrics8010012.
Related InfoLink provided by the sponsor.
Individual participant dataSharing planned: No

Related trials for Mild Cognitive Impairment (MCI)

RecruitingPhase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Alzheimer s Disease, Mild Cognitive Impairment
Active, not recruiting
EFFECTS OF AN OUTDOOR MAT PILATES PROGRAM ON NEUROPHYSIOLOGICAL INDICATORS OF ELDERLY INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT
Cognition Disorders
Recruiting
Combating Alzheimer's Through Sleep and Exercise
Dementia, Mild Cognitive Impairment (MCI)
RecruitingPhase 2
Alzheimer's Tau Platform: Master Protocol
Preclinical Alzheimer's Disease, Alzheimer Disease
RecruitingObservational study
Fuzhou Aging Brain Health Initiative
Dementia, Alzheimer Dementia (AD)

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Healthy aging interventions in people with Mild Cognitive Impairment (MCI) and Dementia, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Mini Mental State Test (time frame: From enrollment to the end of intervention at 8 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07016893, which also lists 18 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jun 2025.