Regional AnesthesiaNCT07021131
Serratus Posterior Plane Block vs Erector Spine Plane Block
A study testing new type of peripheral block Serratus Posterior Plane Block in people with Regional Anesthesia, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. at 1 site in Czechia.
Trial summary
Analgesia related to the administration of local anesthetic solution into the fascia of erector spinae muscle is mediated by the effect of local anesthetic on the posterior and lateral branches of the anterior part of the spinal nerve. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Regional Anesthesia
- What is being tested?
- new type of peripheral block Serratus Posterior Plane Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteCzechia
- Study dates
- 1 Jul 2025to 1 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patiens undergoing VATS-surgery
Who cannot join
- Age < 20 years
- Body Mass Index >35 kg/m2
- Technical difficulties with the nerve block administration and/or subsequent bolus application
- Abnormal course of the surgery (e.g. conversion to thoracotomy) or the postoperative phase (e.g. surgical revision of the chest)
- Patient's refusal
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Czechia1 site
Krajská zdravotní, a.s. - Masarykova nemocnice v Ústí nad Labem, o.z.
Ústí nad Labem, Ústí nad Labem Region, 40011
About this study
Official title: Continuous Serratus Posterior Plane Block Versus Continuous Erector Spine Plane Block for Video-assisted Thoracoscopic Surgery: a Prospective Randomized Non-inferiority Trial
Analgesia related to the administration of local anesthetic solution into the fascia of erector spinae muscle is mediated by the effect of local anesthetic on the posterior and lateral branches of the anterior part of the spinal nerve. Comparable analgesic efficiency after the administration of both nerve blocks would reject the widespread theory of the paravertebral site of effect of the local anesthetic in ESPB.
- Conditions
- Regional Anesthesia
- Being tested
- new type of peripheral block Serratus Posterior Plane Block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
new type of peripheral block Serratus Posterior Plane BlockProcedure or surgery
Intervention will be Serratus Posterior Plane Block.
| Study group | Role | What they receive |
|---|---|---|
| Erector spinae plane block | No intervention | Patients undergoing VATS with the use of continuous peripheral nerve block type A. |
| Serratus Posterior Plane Block | Experimental | Patients undergoing general anaesthesia with continuous peripheral block type B. Receives: Procedure: new type of peripheral block Serratus Posterior Plane Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cumulative opioid dose in 72 hours
Irrespective of the type of the block, 20 mls of 0.25 % bupivacaine will be administered to the block catether every 8 hours. Every patients will receive non-opioid analgesics according to standardized ward guideline. VAS score is recorded at least every 3 hours (except for time patient is asleep). Any time patient reports VAS score >=5, he/she will receive 5 mg of morphine intravenously (or equivalent dose of Oxycodone per os). Cumulative dose of opioids will be recorded.
Measured: from end of surgery to 72 hours after the end surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jun 2025
- Study start1 Jul 2025 (estimated)
- Primary completion1 Dec 2025 (estimated)
- Study completion1 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Regional AnesthesiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Daniel Nalos, Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
- Investigators
- Miroslava Korfova, Principal investigator, Krajská zdravotní, a.s. - Masarykova nemocnice v Ústí nad Labem, o.z.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07021131
- Sponsor's protocol ID
- SERRATUS
- Status last verified
- Jun 2025
- First submitted
- 19 May 2025
- Last updated
- 13 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 13 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Continuous Serratus Posterior Plane Block Versus Continuous Erector Spine Plane Block for Video-assisted Thoracoscopic Surgery: a Prospective Randomized Non-inferiority Trial
- ClinicalTrials.gov ID
- NCT07021131
- Acronym / sponsor ID
- SERRATUS
- Conditions
- Regional Anesthesia
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.University, hospital or other
- Study start
- 1 Jul 2025 (estimated)
- Primary completion
- 1 Dec 2025 (estimated)
- Study completion
- 1 Jul 2026 (estimated)
- First posted
- 13 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Analgesia related to the administration of local anesthetic solution into the fascia of erector spinae muscle is mediated by the effect of local anesthetic on the posterior and lateral branches of the anterior part of the spinal nerve. Comparable analgesic efficiency after the administration of both nerve blocks would reject the widespread theory of the paravertebral site of effect of the local anesthetic in ESPB.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Erector spinae plane block | No intervention | –Patients undergoing VATS with the use of continuous peripheral nerve block type A. |
| Serratus Posterior Plane Block | Experimental | Procedure: new type of peripheral block Serratus Posterior Plane BlockPatients undergoing general anaesthesia with continuous peripheral block type B. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patiens undergoing VATS-surgery
Key exclusion criteria (5 listed)
- Age < 20 years
- Body Mass Index >35 kg/m2
- Technical difficulties with the nerve block administration and/or subsequent bolus application
- Abnormal course of the surgery (e.g. conversion to thoracotomy) or the postoperative phase (e.g. surgical revision of the chest)
- Patient's refusal
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| new type of peripheral block Serratus Posterior Plane BlockIntervention will be Serratus Posterior Plane Block. | Procedure or surgery | Serratus Posterior Plane Block |
Primary outcome
Cumulative opioid dose in 72 hours
Time frame: from end of surgery to 72 hours after the end surgery
Irrespective of the type of the block, 20 mls of 0.25 % bupivacaine will be administered to the block catether every 8 hours. Every patients will receive non-opioid analgesics according to standardized ward guideline. VAS score is recorded at least every 3 hours (except for time patient is asleep). Any time patient reports VAS score >=5, he/she will receive 5 mg of morphine intravenously (or equivalent dose of Oxycodone per os). Cumulative dose of opioids will be recorded.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Jun 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Miroslava Korfova principal investigator
Krajská zdravotní, a.s. - Masarykova nemocnice v Ústí nad Labem, o.z.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing new type of peripheral block Serratus Posterior Plane Block in people with Regional Anesthesia, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. at 1 site in Czechia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Czechia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Daniel Nalos (+420737230792, nalosdan@seznam.cz), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cumulative opioid dose in 72 hours (time frame: from end of surgery to 72 hours after the end surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jun 2025.