Healthcare ProfessionalsNCT07022613
The Impact of Mindfulness-Based Stress Reduction on Mindfulness, Self-Compassion, and Perceived Stress Among Healthcare Professionals
A study testing Mindfulness-Based Stress Reduction Program in people with Healthcare Professionals, run by Akdeniz University.
Trial summary
Mindfulness is defined as a state of awareness in which an individual consciously pays attention to the present moment without judgment, reaction, or resistance, thereby promoting mental and psychological well-being. Self-compassion refers to adopting a kind, understanding, and supportive attitude toward oneself. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthcare Professionals
- What is being tested?
- Mindfulness-Based Stress Reduction Program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- 2 Oct 2025to 1 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- The intervention group consisted of participants whose perceived stress levels were above the arithmetic mean, as measured by the Perceived Stress Scale
- Individuals who provided informed consent to participate in the study.
Who cannot join
- Individuals with communication impairments (e.g., hearing, vision, or speech difficulties)
- Individuals currently engaged in stress-reducing practices such as yoga or various forms of meditation
- Pregnant individuals
- Individuals receiving medical or psychosocial treatment
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Mindfulness is defined as a state of awareness in which an individual consciously pays attention to the present moment without judgment, reaction, or resistance, thereby promoting mental and psychological well-being.
Self-compassion refers to adopting a kind, understanding, and supportive attitude toward oneself. While mindfulness enables individuals to recognize sources of stress and develop strategies to cope with them, self-compassion encourages a gentle and caring approach toward oneself during this process. Research has shown that mindfulness practices enhance self-compassion and that these two constructs have a synergistic effect in reducing stress.
Read more
Work-related stress negatively affects both the professional functioning and overall health of individuals. Acknowledging the increasing prevalence of stress and stress-related illnesses, the International Labour Organization (ILO) officially included stress and stress-induced disorders in the list of occupational diseases in 2010. Compared to other professions, these stressors have a more profound physical and psychological impact on healthcare professionals. In this context, the concepts of mindfulness and self-compassion are critically important for enhancing the psychological resilience of healthcare professionals and improving their stress management skills.
This study is designed as a non-randomized, quasi-experimental pretest-posttest control group study to determine the effect of the Mindfulness-Based Stress Reduction (MBSR) program on the levels of mindfulness, self-compassion, and stress among healthcare professionals. Data collection tools will include a demographic information form, the Perceived Stress Scale (PSS), Mindful Attention Awareness Scale (MAAS), the A Scale to Mearsure Self-Compassion (SCS), and a Visual Analog Scale (VAS) for stress assessment. The research will be conducted with healthcare professionals working at Aksaray Training and Research Hospital, located in the central district of Aksaray, Turkey.
An 8-week Mindfulness-Based Stress Reduction (MBSR) program will be implemented for the intervention group. Data will be collected between May and December 2025. The results of the study will be analyzed using the Statistical Package for the Social Sciences (SPSS) version 25. In addition to standardized scales, the effectiveness of the MBSR program will also be evaluated using a biological stress marker-salivary cortisol.
The Mindfulness-Based Stress Reduction program implemented in this study is expected to contribute to the field of occupational health nursing. Furthermore, the program is anticipated to enhance healthcare professionals' abilities to consciously recognize their emotions, accept painful experiences with understanding rather than suppression, and transform negative thoughts and emotions into more constructive perspectives.
- Conditions
- Healthcare Professionals
- Being tested
- Mindfulness-Based Stress Reduction Program
- Keywords
- stress, Mindfulness, Self-Compassion, Healthcare Professionals, Occupational Health Nurse, Nursing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mindfulness-Based Stress Reduction ProgramOther
Also called Perceived Stress Scale, Mindful Attention Awareness Scale, A Scale to Mearsure Self-Compassion, Visual Analog Scale
The Mindfulness-Based Stress Reduction (MBSR) program is considered to offer healthcare professionals working under high levels of stress the opportunity to develop knowledge and skills in consciously recognizing their emotions, compassionately accepting painful feelings without suppression, and transforming negative thoughts and emotions into more constructive ones.
In the first and last sessions, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected.
In the remaining sessions, only the VAS-one of the stress measurement parameters-will be verbally administered. In this way, participants will be informed weekly about the progression of their stress levels.
The program to be implemented in the study will consist of weekly sessions held over eight weeks. Each session will be conducted for groups of 10 participants, three consecutive days
| Study group | Role | What they receive |
|---|---|---|
| program designed specifically for healthcare professionals, the intervention group | Experimental | In the first and last sessions, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected.
In the remaining sessions, only the VAS-one of the stress measurement parameters-will be verbally administered. In this way, participants will be informed weekly about the progression of their stress levels.
The program to be implemented in the study will consist of weekly sessions held over eight weeks. Each session will be conducted for groups of 10 participants, three consecutive days per week. Receives: Other: Mindfulness-Based Stress Reduction Program |
| control group | No intervention | Participants will be interviewed twice: once at the beginning and once at the end of the intervention.During both the initial and final interviews, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Perceived Stress Scale
The Perceived Stress Scale (PSS) was developed by Cohen, Kamarck, and Mermelstein (1983).The PSS consists of 14 items and is designed to measure the degree to which situations in one's life are perceived as stressful. The internal consistency reliability of the scale, calculated based on item analysis, yielded a Cronbach's alpha coefficient of 0.84, and the test-retest correlation was found to be 0.87.
Participants evaluate each item on a 5-point Likert-type scale ranging from "Never (0)" to "Very Often (4)." The scale comprises two subdimensions: perceived distress and perceived lack of control/self-efficacy. Items 1, 2, 3, 7, 11, 12, and 14 assess perceived distress, while items 4, 5, 6, 8, 9, 10, and 13 assess perceived lack of self-efficacy. Seven of the items, which are positively worded, are reverse scored. The total score on the PSS-14 ranges from 0 to 56, with higher scores indicating greater perceived stress.
Measured: Participants will complete the scale once in the first phase of the study, and again during the first and final (eighth) weeks of the second phase."
Mindful Attention Awareness Scale
The Mindful Attention Awareness Scale (MAAS) was developed by Brown and Ryan (2003), and its Turkish validity and reliability study was conducted by Özyeşil et al. (2011).
The scale has a Cronbach's alpha internal consistency coefficient of .80 and a test-retest correlation of .86. The MAAS measures the general tendency to be aware of and attentive to present-moment experiences in daily life.
It consists of 15 items and is rated on a 6-point Likert-type scale (almost always, very frequently, sometimes, rarely, very rarely, almost never). The scale has a unidimensional structure and yields a single total score. Higher scores on the scale indicate higher levels of mindfulness.
Measured: In the second phase of the study, the scale will be administered in both the first and the final (eighth) week.
A Scale to Mearsure Self-Compassion
The Self-Compassion Scale (SCS) was developed by Neff in 2003 and consists of 26 items.
The scale measures six subdimensions: self-kindness, self-judgment, common humanity, isolation, mindfulness, and over-identification. It is rated on a 5-point Likert-type scale (1 = Almost Never, 2 = Rarely, 3 = Sometimes, 4 = Often, 5 = Almost Always).
The overall reliability of the scale is high, with a Cronbach's alpha coefficient of .92. For the subscales, Cronbach's alpha values range between .75 and .81, indicating good internal consistency.
Measured: In the second phase of the study, the scale will be administered in both the first and the final (eighth) week.
Visual Analog Scale
At the beginning of each session conducted with the intervention group in the second phase of the study, it is planned to use the Visual Analog Scale (VAS) to assess the participants' stress levels based on the previous week's evaluation.
The Visual Analog Scale (VAS) is a tool used to convert subjective, non-quantifiable values into numerical data. It consists of a 10-centimeter horizontal line marked with numbers from 1 to 10 at one-centimeter intervals. The VAS is a well-established and widely accepted assessment instrument in the global scientific literature.Within the context of this study, a score of 10 on the Visual Analog Scale (VAS) will represent the highest level of perceived stress ('very stressed'), whereas a score of 0 will represent the absence of stress ('not stressed at all
Measured: At the beginning of each session conducted with the intervention group in the second phase of the study, it is planned to use the Visual Analog Scale (VAS) to assess the participants' stress levels based on the previous week's evaluation.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jun 2025
- Study start2 Oct 2025 (estimated)
- Primary completion1 Jan 2026 (estimated)
- Study completion1 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Healthcare ProfessionalsStudies of the same condition, open and under way.
- More trials run by Akdeniz UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Akdeniz University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, birgül yazar, Akdeniz University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07022613
- Sponsor's protocol ID
- AkdenizU-SBF-BY-01
- Status last verified
- Jun 2025
- First submitted
- 7 Jun 2025
- Last updated
- 15 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Andersen E, Geiger P, Schiller C, Bluth K, Watkins L, Zhang Y, Xia K, Tauseef H, Leserman J, Girdler S, Gaylord S. Effects of Mindfulness-Based Stress Reduction on Experimental Pain Sensitivity and Cortisol Responses in Women With Early Life Abuse: A Randomized Controlled Trial. Psychosom Med. 2021 Jul-Aug 01;83(6):515-527. doi: 10.1097/PSY.0000000000000889.
PubMed 33259351
Study at a glance
From the registry record, last updated by the sponsor on 15 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Impact of Mindfulness-Based Stress Reduction on Mindfulness, Self-Compassion, and Perceived Stress Among Healthcare Professionals
- ClinicalTrials.gov ID
- NCT07022613
- Acronym / sponsor ID
- AkdenizU-SBF-BY-01
- Conditions
- Healthcare Professionals
- Keywords
- stress, Mindfulness, Self-Compassion, Healthcare Professionals, Occupational Health Nurse, Nursing
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Akdeniz UniversityUniversity, hospital or other
- Study start
- 2 Oct 2025 (estimated)
- Primary completion
- 1 Jan 2026 (estimated)
- Study completion
- 1 May 2026 (estimated)
- First posted
- 15 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mindfulness is defined as a state of awareness in which an individual consciously pays attention to the present moment without judgment, reaction, or resistance, thereby promoting mental and psychological well-being.
Self-compassion refers to adopting a kind, understanding, and supportive attitude toward oneself. While mindfulness enables individuals to recognize sources of stress and develop strategies to cope with them, self-compassion encourages a gentle and caring approach toward oneself during this process. Research has shown that mindfulness practices enhance self-compassion and that these two constructs have a synergistic effect in reducing stress.
Work-related stress negatively affects both the professional functioning and overall health of individuals. Acknowledging the increasing prevalence of stress and stress-related illnesses, the International Labour Organization (ILO) officially included stress and stress-induced disorders in the list of occupational diseases in 2010. Compared to other professions, these stressors have a more profound physical and psychological impact on healthcare professionals. In this context, the concepts of mindfulness and self-compassion are critically important for enhancing the psychological resilience of healthcare professionals and improving their stress management skills.
This study is designed as a non-randomized, quasi-experimental pretest-posttest control group study to determine the effect of the Mindfulness-Based Stress Reduction (MBSR) program on the levels of mindfulness, self-compassion, and stress among healthcare professionals. Data collection tools will include a demographic information form, the Perceived Stress Scale (PSS), Mindful Attention Awareness Scale (MAAS), the A Scale to Mearsure Self-Compassion (SCS), and a Visual Analog Scale (VAS) for stress assessment. The research will be conducted with healthcare professionals working at Aksaray Training and Research Hospital, located in the central district of Aksaray, Turkey.
An 8-week Mindfulness-Based Stress Reduction (MBSR) program will be implemented for the intervention group. Data will be collected between May and December 2025. The results of the study will be analyzed using the Statistical Package for the Social Sciences (SPSS) version 25. In addition to standardized scales, the effectiveness of the MBSR program will also be evaluated using a biological stress marker-salivary cortisol.
The Mindfulness-Based Stress Reduction program implemented in this study is expected to contribute to the field of occupational health nursing. Furthermore, the program is anticipated to enhance healthcare professionals' abilities to consciously recognize their emotions, accept painful experiences with understanding rather than suppression, and transform negative thoughts and emotions into more constructive perspectives.
Study design
- Primary purpose
- Health services research
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| program designed specifically for healthcare professionals, the intervention group | Experimental | Other: Mindfulness-Based Stress Reduction ProgramIn the first and last sessions, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected. In the remaining sessions, only the VAS-one of the stress measurement parameters-will be verbally administered. In this way, participants will be informed weekly about the progression of their stress levels. The program to be implemented in the study will consist of weekly sessions held over eight weeks. Each session will be conducted for groups of 10 participants, three consecutive days per week. |
| control group | No intervention | –Participants will be interviewed twice: once at the beginning and once at the end of the intervention.During both the initial and final interviews, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- The intervention group consisted of participants whose perceived stress levels were above the arithmetic mean, as measured by the Perceived Stress Scale
- Individuals who provided informed consent to participate in the study.
Key exclusion criteria (4 listed)
- Individuals with communication impairments (e.g., hearing, vision, or speech difficulties)
- Individuals currently engaged in stress-reducing practices such as yoga or various forms of meditation
- Pregnant individuals
- Individuals receiving medical or psychosocial treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mindfulness-Based Stress Reduction ProgramAlso: Perceived Stress Scale, Mindful Attention Awareness Scale, A Scale to Mearsure Self-Compassion, Visual Analog ScaleThe Mindfulness-Based Stress Reduction (MBSR) program is considered to offer healthcare professionals working under high levels of stress the opportunity to develop knowledge and skills in consciously recognizing their emotions, compassionately accepting painful feelings without suppression, and transforming negative thoughts and emotions into more constructive ones. In the first and last sessions, the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), the Self-Compassion Scale (SCS), and the Visual Analog Scale (VAS) will be administered, and saliva samples will be collected. In the remaining sessions, only the VAS-one of the stress measurement parameters-will be verbally administered. In this way, participants will be informed weekly about the progression of their stress levels. The program to be implemented in the study will consist of weekly sessions held over eight weeks. Each session will be conducted for groups of 10 participants, three consecutive days | Other | program designed specifically for healthcare professionals, the intervention group |
Primary outcome
Perceived Stress Scale
Time frame: Participants will complete the scale once in the first phase of the study, and again during the first and final (eighth) weeks of the second phase."
The Perceived Stress Scale (PSS) was developed by Cohen, Kamarck, and Mermelstein (1983).The PSS consists of 14 items and is designed to measure the degree to which situations in one's life are perceived as stressful. The internal consistency reliability of the scale, calculated based on item analysis, yielded a Cronbach's alpha coefficient of 0.84, and the test-retest correlation was found to be 0.87. Participants evaluate each item on a 5-point Likert-type scale ranging from "Never (0)" to "Very Often (4)." The scale comprises two subdimensions: perceived distress and perceived lack of control/self-efficacy. Items 1, 2, 3, 7, 11, 12, and 14 assess perceived distress, while items 4, 5, 6, 8, 9, 10, and 13 assess perceived lack of self-efficacy. Seven of the items, which are positively worded, are reverse scored. The total score on the PSS-14 ranges from 0 to 56, with higher scores indicating greater perceived stress.
Mindful Attention Awareness Scale
Time frame: In the second phase of the study, the scale will be administered in both the first and the final (eighth) week.
The Mindful Attention Awareness Scale (MAAS) was developed by Brown and Ryan (2003), and its Turkish validity and reliability study was conducted by Özyeşil et al. (2011). The scale has a Cronbach's alpha internal consistency coefficient of .80 and a test-retest correlation of .86. The MAAS measures the general tendency to be aware of and attentive to present-moment experiences in daily life. It consists of 15 items and is rated on a 6-point Likert-type scale (almost always, very frequently, sometimes, rarely, very rarely, almost never). The scale has a unidimensional structure and yields a single total score. Higher scores on the scale indicate higher levels of mindfulness.
A Scale to Mearsure Self-Compassion
Time frame: In the second phase of the study, the scale will be administered in both the first and the final (eighth) week.
The Self-Compassion Scale (SCS) was developed by Neff in 2003 and consists of 26 items. The scale measures six subdimensions: self-kindness, self-judgment, common humanity, isolation, mindfulness, and over-identification. It is rated on a 5-point Likert-type scale (1 = Almost Never, 2 = Rarely, 3 = Sometimes, 4 = Often, 5 = Almost Always). The overall reliability of the scale is high, with a Cronbach's alpha coefficient of .92. For the subscales, Cronbach's alpha values range between .75 and .81, indicating good internal consistency.
Visual Analog Scale
Time frame: At the beginning of each session conducted with the intervention group in the second phase of the study, it is planned to use the Visual Analog Scale (VAS) to assess the participants' stress levels based on the previous week's evaluation.
At the beginning of each session conducted with the intervention group in the second phase of the study, it is planned to use the Visual Analog Scale (VAS) to assess the participants' stress levels based on the previous week's evaluation. The Visual Analog Scale (VAS) is a tool used to convert subjective, non-quantifiable values into numerical data. It consists of a 10-centimeter horizontal line marked with numbers from 1 to 10 at one-centimeter intervals. The VAS is a well-established and widely accepted assessment instrument in the global scientific literature.Within the context of this study, a score of 10 on the Visual Analog Scale (VAS) will represent the highest level of perceived stress ('very stressed'), whereas a score of 0 will represent the absence of stress ('not stressed at all
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jun 2025.
- Results publication: PubMed 33259351Andersen E, Geiger P, Schiller C, Bluth K, Watkins L, Zhang Y, Xia K, Tauseef H, Leserman J, Girdler S, Gaylord S. Effects of Mindfulness-Based Stress Reduction on Experimental Pain Sensitivity and Cortisol Responses in Women With Early Life Abuse: A Randomized Controlled Trial. Psychosom Med. 2021 Jul-Aug 01;83(6):515-527. doi: 10.1097/PSY.0000000000000889.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Mindfulness-Based Stress Reduction Program in people with Healthcare Professionals, run by Akdeniz University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 15 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact LEYLA MUSLU (+905369488003 ext. +905072226632, leylamuslu@akdeniz.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Perceived Stress Scale (time frame: Participants will complete the scale once in the first phase of the study, and again during the first and final (eighth) weeks of the second phase."). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07022613, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jun 2025.