Investigating the Effects of Power Training in the ElderlyNCT07023146

Effects of Different Power Training Intensities in Older Adults

A study testing Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ) and low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM]) in people with Investigating the Effects of Power Training in the Elderly, run by Federal University of Rio Grande do Sul at 1 site in Brazil.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts

Official record

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Trial summary

Who is it for?: Ages 60 years and olderHealthy volunteers can take part
Conditions the study is for: Investigating the Effects of Power Training in the Elderly
What is being tested?: Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ) and low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
Type of treatment: Medical device
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 70 participants
Where: 1 siteBrazil
Study dates: 2 Apr 2025to 11 Dec 2025
Phase: Interventional
Are there results?: Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 60 years and older
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Age 60 years or older
No participation in regular and systematic resistance training in the last three months
No absolute or relative contraindications to exercise
No musculoskeletal injuries that could interfere with training and assessments

Who cannot join

Use of steroids, nutritional supplements, or ergogenic substances
Failure to complete all study phases
Failure to complete more than 80% of the training sessions (32 sessions)

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Brazil1 site

Universidade Federal do Rio Grande do Sul (UFRGS)
Porto Alegre, Rio Grande do Sul, 91410-070

Other trials in Brazil

About this study

Official title: Adaptations Due to Different Intensities of Power Training on Neuromuscular Performance, Muscle Thickness and Functional Capacity in Elderly People: A Randomized Clinical Trial

Power (strength × velocity) is a crucial component for maintaining independence during aging. Therefore, investigating interventions aimed at improving this physical capacity is essential for this population. The aim of this study is to examine the effects of power training (PT) performed at low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM]) and moderate to high intensity (PTMH; 65-80% of 1RM) on muscle power, kinematic gait parameters, strength, muscle thickness, and functional performance in older adults. Participants will be randomly assigned to perform PTLM and PTMH. Data collection will occur before and after familiarization, as well as at weeks 8 and 16 of the training programs. Participants will undergo a series of tests in the following sequence: 1) muscle thickness and 1RM test; 2) muscle power, maximum voluntary contraction, and rate of force development; 3) functional performance. The primary analyses will be conducted on an intention-to-treat basis, comparing the effects of the interventions and groups over time. Generalized Estimating Equations (GEE) will be used, considering the factors of group (2 levels) and time (3 levels). Paired comparisons will be assessed using the Bonferroni post-hoc test to identify significant differences between groups and time points. All tests will be performed using JASP software (version 0.16.4.0), with statistical significance set at p < 0.05 for all analyses.

Conditions: Investigating the Effects of Power Training in the Elderly
Being tested: Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ), low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
Keywords: Aging, resistance training, functional capacity, muscle strength, muscle hypertrophy

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) )Device
Also called PTMH, Linear Encoder, Load Cell, 1-Repetition Maximum (1RM)
Power training performed at maximum velocity in the concentric phase with moderate to high intensity
low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])Device
Also called PTLM, Linear Encoder, 1-Repetition Maximum (1RM), Ultrasound
Power training performed at maximum velocity in the concentric phase with lower to moderate intensity

Study groups in NCT07023146
Study group	Role	What they receive
Low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])	Active comparator	Power training performed at maximum velocity in the concentric phase with lower to moderate intensity Receives: Device: low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
Moderate to high intensity (PTMH; 65-80% % of 1-repetition maximum [1RM])	Active comparator	Power training performed at maximum velocity in the concentric phase with moderate to high intensity Receives: Device: Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) )

What is being measured

The primary outcome is the main question the study is designed to answer.

Muscle Power
The power output during strength exercises is assessed using an encoder linear at two different intensities: 30% and 70% of 1RM in leg extension and leg press 45. Power output is the ability to generate force quickly and is a key measure of explosive strength. These tests are performed using different resistance levels to assess power across a range of intensities.
Measurement Tool: Encoder linear (linear encoder or velocity-based device)
Scale: Power output in watts (W)
Higher scores indicate better power performance at each intensity.
Measured: Pre- and post-intervention (16 weeks of training)
Muscle Strength
Muscle strength is the ability of a muscle or muscle group to generate force against resistance. It reflects the maximum force that can be produced in a single effort and is essential for daily activities and overall physical function. One Repetition Maximum (1RM) is used to quantify maximal strength.
Measurement Tool: 1RM testing
Scale: 1RM (measured in kg)
Higher scores indicate better strength performance.
Measured: Pre- and post-intervention (16 weeks of training)
Rate of Force Development
Rate of force development refers to the speed at which force is generated by a muscle or muscle group. It is a critical measure of neuromuscular performance, especially in activities that require explosive strength or rapid reactions. RFD is measured during maximal voluntary contractions.
Measurement Tool: Load Cell
Scale: Measured in Newtons per second (N/s)
Higher scores indicate better neuromuscular performance.
Measured: Pre- and post-intervention (16 weeks of training)

Secondary outcomes (3)

Functional Capacity
Functional capacity refers to an individual's ability to perform activities required for daily living, such as walking, climbing stairs, or carrying objects. It reflects overall physical function and is often used to assess health status, particularly in older adults or clinical populations. The following tests were selected to assess functional capacity:
Stair Climbing Test Scale: Total time to climb and descend a predetermined number of stairs. Shorter time indicates better performance. Timed Up and Go (TUG) Scale: Total time in seconds. Shorter time indicates better mobility and agility. 6-Meter Walk Speed Test Scale: Total time to walk 6 meters (seconds). Shorter time indicates faster walking speed. Sit-to-Stand Test (5 times) Scale: Total time to complete the 5 repetitions. Shorter time indicates better muscle strength and functional capacity.
Measured: Pre- and post-intervention (16 weeks of training)
Muscle hypertrophy
Muscle thickness is an indicator of muscle size and hypertrophy. It reflects the structural adaptations that occur in response to training. Ultrasound is used to measure the thickness of muscles such as the quadriceps, biceps, and triceps.
Measurement Tool: Ultrasound imaging
Scale: Muscle thickness in millimeters (mm)
Higher scores indicate greater muscle hypertrophy.
Measured: Pre- and post-intervention (16 weeks of training)
Cognitive Capacity
The Montreal Cognitive Assessment (MoCA) is a brief screening tool used to assess cognitive function. It evaluates multiple cognitive domains, including memory, attention, language, and executive functions. It is commonly used to assess cognitive decline or impairments.
Measurement Tool: MoCA test
Scale: MoCA score ranges from 0 to 30, with higher scores indicating better cognitive function.
Higher scores indicate better cognitive function.
Measured: Pre- and post-intervention (16 weeks of training)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

2 Apr 202511 Dec 2025

First posted15 Jun 2025
Study start2 Apr 2025
Primary completion11 Dec 2025 (estimated)
Study completion11 Dec 2025 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (4)Papers the sponsor has linked to this study.
Other trials for Investigating the Effects of Power Training in the ElderlyStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Prevention
Allocation: Randomised
Intervention model: Parallel groups
Model description: The methodological procedures of this project will be carried out at the UFRGS facilities, on the campus of the School of Physical Education, Physiotherapy and Dance (ESEFID) and at LAPEX. After two weeks of familiarization, in order to guarantee the reproducibility and reliability of the methodological procedures, the participants will be randomized electronically (randomizer.org.br) to perform low to moderate intensity (PTLM; 40-60% of 1-repetition maximum \[1RM\]) and moderate to high intensity (PTMH; 65-80% of 1RM).
Masking: Triple blind
Who is masked: Participant, Care provider, Outcomes assessor
Enrolment: 70 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07023146
Sponsor's protocol ID: 85503024.6.0000.5347
Status last verified: Jun 2025
First submitted: 23 May 2025
Last updated: 15 Jun 2025
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Martinikorena I, Martinez-Ramirez A, Gomez M, Lecumberri P, Casas-Herrero A, Cadore EL, Millor N, Zambom-Ferraresi F, Idoate F, Izquierdo M. Gait Variability Related to Muscle Quality and Muscle Power Output in Frail Nonagenarian Older Adults. J Am Med Dir Assoc. 2016 Feb;17(2):162-7. doi: 10.1016/j.jamda.2015.09.015. Epub 2015 Nov 11.
PubMed 26577625
Mc Dermott EJ, Balshaw TG, Brooke-Wavell K, Maden-Wilkinson TM, Folland JP. Fast and ballistic contractions involve greater neuromuscular power production in older adults during resistance exercise. Eur J Appl Physiol. 2022 Jul;122(7):1639-1655. doi: 10.1007/s00421-022-04947-x. Epub 2022 Apr 16.
PubMed 35429294
Bandeira-Guimaraes M, Blanco-Rambo E, Vieira AF, Saez de Asteasu ML, Pinto RS, Izquierdo M, Cadore EL. Chronic Effects of Different Intensities of Power Training on Neuromuscular Parameters in Older People: A Systematic Review with Meta-analysis. Sports Med Open. 2023 Oct 24;9(1):98. doi: 10.1186/s40798-023-00646-9.
PubMed 37874417
de Vos NJ, Singh NA, Ross DA, Stavrinos TM, Orr R, Fiatarone Singh MA. Optimal load for increasing muscle power during explosive resistance training in older adults. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):638-47. doi: 10.1093/gerona/60.5.638.
PubMed 15972618

Study at a glance

From the registry record, last updated by the sponsor on 15 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Adaptations Due to Different Intensities of Power Training on Neuromuscular Performance, Muscle Thickness and Functional Capacity in Elderly People: A Randomized Clinical Trial
ClinicalTrials.gov ID: NCT07023146
Acronym / sponsor ID: 85503024.6.0000.5347
Conditions: Investigating the Effects of Power Training in the Elderly
Keywords: Aging, resistance training, functional capacity, muscle strength, muscle hypertrophy
Study type: Interventional
Recruitment status: Enrolling by invitation
Enrolment: 70 participants (estimated)
Lead sponsor: Federal University of Rio Grande do SulUniversity, hospital or other
Study start: 2 Apr 2025 (actual)
Primary completion: 11 Dec 2025 (estimated)
Study completion: 11 Dec 2025 (estimated)
First posted: 15 Jun 2025 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Prevention
Allocation: Randomised
Intervention model: Parallel groups
Masking: Triple blind (participant, care provider, outcomes assessor)
Number of arms: 2
Model description: The methodological procedures of this project will be carried out at the UFRGS facilities, on the campus of the School of Physical Education, Physiotherapy and Dance (ESEFID) and at LAPEX. After two weeks of familiarization, in order to guarantee the reproducibility and reliability of the methodological procedures, the participants will be randomized electronically (randomizer.org.br) to perform low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM]) and moderate to high intensity (PTMH; 65-80% of 1RM).

Arm	Type	Receives
Low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])	Active comparator	Device: low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])Power training performed at maximum velocity in the concentric phase with lower to moderate intensity
Moderate to high intensity (PTMH; 65-80% % of 1-repetition maximum [1RM])	Active comparator	Device: Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) )Power training performed at maximum velocity in the concentric phase with moderate to high intensity

Who may qualify

Ages: 60 years and older
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (4 listed)

Age 60 years or older
No participation in regular and systematic resistance training in the last three months
No absolute or relative contraindications to exercise
No musculoskeletal injuries that could interfere with training and assessments

Key exclusion criteria (3 listed)

Use of steroids, nutritional supplements, or ergogenic substances
Failure to complete all study phases
Failure to complete more than 80% of the training sessions (32 sessions)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) )Also: PTMH, Linear Encoder, Load Cell, 1-Repetition Maximum (1RM)Power training performed at maximum velocity in the concentric phase with moderate to high intensity	Device	Moderate to high intensity (PTMH; 65-80% % of 1-repetition maximum [1RM])
low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])Also: PTLM, Linear Encoder, 1-Repetition Maximum (1RM), UltrasoundPower training performed at maximum velocity in the concentric phase with lower to moderate intensity	Device	Low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])

Primary outcome

Muscle Power
Time frame: Pre- and post-intervention (16 weeks of training)
The power output during strength exercises is assessed using an encoder linear at two different intensities: 30% and 70% of 1RM in leg extension and leg press 45. Power output is the ability to generate force quickly and is a key measure of explosive strength. These tests are performed using different resistance levels to assess power across a range of intensities. Measurement Tool: Encoder linear (linear encoder or velocity-based device) Scale: Power output in watts (W) Higher scores indicate better power performance at each intensity.
Muscle Strength
Time frame: Pre- and post-intervention (16 weeks of training)
Muscle strength is the ability of a muscle or muscle group to generate force against resistance. It reflects the maximum force that can be produced in a single effort and is essential for daily activities and overall physical function. One Repetition Maximum (1RM) is used to quantify maximal strength. Measurement Tool: 1RM testing Scale: 1RM (measured in kg) Higher scores indicate better strength performance.
Rate of Force Development
Time frame: Pre- and post-intervention (16 weeks of training)
Rate of force development refers to the speed at which force is generated by a muscle or muscle group. It is a critical measure of neuromuscular performance, especially in activities that require explosive strength or rapid reactions. RFD is measured during maximal voluntary contractions. Measurement Tool: Load Cell Scale: Measured in Newtons per second (N/s) Higher scores indicate better neuromuscular performance.

3 secondary outcomes

Functional Capacity
Time frame: Pre- and post-intervention (16 weeks of training)
Muscle hypertrophy
Time frame: Pre- and post-intervention (16 weeks of training)
Cognitive Capacity
Time frame: Pre- and post-intervention (16 weeks of training)

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 15 Jun 2025.
Background: PubMed 26577625Martinikorena I, Martinez-Ramirez A, Gomez M, Lecumberri P, Casas-Herrero A, Cadore EL, Millor N, Zambom-Ferraresi F, Idoate F, Izquierdo M. Gait Variability Related to Muscle Quality and Muscle Power Output in Frail Nonagenarian Older Adults. J Am Med Dir Assoc. 2016 Feb;17(2):162-7. doi: 10.1016/j.jamda.2015.09.015. Epub 2015 Nov 11.
Background: PubMed 35429294Mc Dermott EJ, Balshaw TG, Brooke-Wavell K, Maden-Wilkinson TM, Folland JP. Fast and ballistic contractions involve greater neuromuscular power production in older adults during resistance exercise. Eur J Appl Physiol. 2022 Jul;122(7):1639-1655. doi: 10.1007/s00421-022-04947-x. Epub 2022 Apr 16.
Background: PubMed 37874417Bandeira-Guimaraes M, Blanco-Rambo E, Vieira AF, Saez de Asteasu ML, Pinto RS, Izquierdo M, Cadore EL. Chronic Effects of Different Intensities of Power Training on Neuromuscular Parameters in Older People: A Systematic Review with Meta-analysis. Sports Med Open. 2023 Oct 24;9(1):98. doi: 10.1186/s40798-023-00646-9.
Background: PubMed 15972618de Vos NJ, Singh NA, Ross DA, Stavrinos TM, Orr R, Fiatarone Singh MA. Optimal load for increasing muscle power during explosive resistance training in older adults. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):638-47. doi: 10.1093/gerona/60.5.638.
Related InfoLink provided by the sponsor.
Related InfoLink provided by the sponsor.
Individual participant dataSharing planned: No

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 15 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Muscle Power (time frame: Pre- and post-intervention (16 weeks of training)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07023146, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jun 2025.