Breathing TechniquesNCT07025616
Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma
A study testing Buteyko in people with Breathing Techniques and Asthma Control Level, run by Ivan Sofian Wibowo at 1 site in Indonesia.
Trial summary
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with uncontrolled asthma. Read more about this study
- Who is it for?
- Ages 7 to 17 years
- Conditions the study is for
- Breathing Techniques, Asthma Control Level, Asthma in Children
- What is being tested?
- Buteyko
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 74 participants
- Where
- 1 siteIndonesia
- Study dates
- Jun 2025to Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 7 to 17 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Children aged 7-17 years
- Uncontrolled or partially controlled asthma (GINA Symptom Control Tool score > 1)
- Receive bronchodilator therapy, either oral or inhaler from a pediatrician.
- Children and parents/care givers agree to participate in the study until the end, and parents/care givers sign the informed consent form.
- Can understand instructions.
Who cannot join
- Inpatients
- Have received Buteyko breathing exercises or other breathing exercises.
- Have congenital heart disease, pneumonia, or other significant and uncontrolled health disorders.
- Have severe physical disabilities or mental retardation that could potentially prevent the implementation of Buteyko breathing exercises.
- Have contraindications for spirometry examination
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Indonesia1 site
Universitas Indonesia, Faculty of Medicine
Jakarta Pusat, Dki Jakarta, 10430
Ivan S Wibowo, Medical Doctor, +6285647581213, ivan_sofian@yahoo.com
About this study
Official title: Effectiveness of Buteyko Breathing Exercise in Children With Uncontrolled Asthma: A Single Blind, Randomized Controlled Trial
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with uncontrolled asthma.
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients, Breathing Exercise
- Being tested
- Buteyko, Asthma reliever and controller
- Keywords
- Asthma, Buteyko, breathing retraining, pediatrics
- Medical subject headings
- Asthma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ButeykoBehavioural
The Buteyko breathing exercise is a method that encourages nasal breathing, reducing breathing volume, and using breath-holding exercises to normalize breathing pattern
Asthma reliever and controllerDrug
Asthma reliever and controller according to GINA (Global Initiative for Asthma) guideline
| Study group | Role | What they receive |
|---|---|---|
| Buteyko | Experimental | Buteyko breathing exercise plus pharmacological treatment Receives: Behavioral: Buteyko; Drug: Asthma reliever and controller |
| Control | Active comparator | Pharmacological treatment Receives: Drug: Asthma reliever and controller |
What is being measured
The primary outcome is the main question the study is designed to answer.
Asthma control
Level of asthma control measured by Asthma Control Questionnaire (ACQ) - Indonesian version.
Minimum value 0, maximum value 6. Higher score means worse outcome.
Measured: At enrollment and end of fourth-week
Secondary outcomes (7)
Asthma Quality of Life
Measured by Pediatric Asthma Quality of Life Questionnaire standardized version (PAQLQ(S)) - Indonesian version.
Minimum value 1, maximum value 7. Higher scores means better outcome.
Measured: At enrollment and end of fourth-week
Bronchodilator use
Bronchodilator use measured by logbook, recorded by caregiver of patients
Measured: At end of fourth-week
FEV1
Forced Expiratory Volume in one second reflects degree of airway obstruction. Measured by spirometry.
Measured: At enrollment and end of fourth-week
FVC
Forced Vital Capacity is total volume of air that can forcefully exhale after taking the deepest possible breath. Measured by spirometry.
Measured: At enrollment and end of fourth-week
FEV1/FVC
Ratio of Forced Expiratory Volume in 1 second (FEV₁) to the Forced Vital Capacity (FVC). Measured by spirometry.
Measured: At enrollment and end of fourth-week
PEFR
Peak Expiratory Flow Rate is maximum speed (flow rate) of air that can be blowed out in a single forced breath. Measured by spirometry.
Measured: At enrollment and end of fourth-week
Control Pause
Duration of control pause
Measured: At enrollment and end of fourth-week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2025
- Study startJun 2025 (estimated)
- Primary completionDec 2025 (estimated)
- Study completionDec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Breathing TechniquesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 74 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ivan Sofian Wibowo
- Sponsor type
- University, hospital or other
- Collaborators
- Fakultas Kedokteran Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital
- Responsible party
- Sponsor-investigator, Ivan Sofian Wibowo, Universitas Indonesia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07025616
- Sponsor's protocol ID
- 24-07-1177
- Status last verified
- Jun 2025
- First submitted
- 8 Jun 2025
- Last updated
- 17 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Buteyko Breathing Exercise in Children With Uncontrolled Asthma: A Single Blind, Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07025616
- Acronym / sponsor ID
- 24-07-1177
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients, Breathing Exercise
- Keywords
- Asthma, Buteyko, breathing retraining, pediatrics
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 74 participants (estimated)
- Lead sponsor
- Ivan Sofian WibowoUniversity, hospital or other
- Collaborators
- Fakultas Kedokteran Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital
- Study start
- Jun 2025 (estimated)
- Primary completion
- Dec 2025 (estimated)
- Study completion
- Dec 2025 (estimated)
- First posted
- 17 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with uncontrolled asthma.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Buteyko | Experimental | Behavioral: Buteyko, Drug: Asthma reliever and controllerButeyko breathing exercise plus pharmacological treatment |
| Control | Active comparator | Drug: Asthma reliever and controllerPharmacological treatment |
Who may qualify
- Ages
- 7 to 17 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- Children aged 7-17 years
- Uncontrolled or partially controlled asthma (GINA Symptom Control Tool score > 1)
- Receive bronchodilator therapy, either oral or inhaler from a pediatrician.
- Children and parents/care givers agree to participate in the study until the end, and parents/care givers sign the informed consent form.
- Can understand instructions.
Key exclusion criteria (5 listed)
- Inpatients
- Have received Buteyko breathing exercises or other breathing exercises.
- Have congenital heart disease, pneumonia, or other significant and uncontrolled health disorders.
- Have severe physical disabilities or mental retardation that could potentially prevent the implementation of Buteyko breathing exercises.
- Have contraindications for spirometry examination
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ButeykoThe Buteyko breathing exercise is a method that encourages nasal breathing, reducing breathing volume, and using breath-holding exercises to normalize breathing pattern | Behavioural | Buteyko |
| Asthma reliever and controllerAsthma reliever and controller according to GINA (Global Initiative for Asthma) guideline | Drug | Buteyko, Control |
Primary outcome
Asthma control
Time frame: At enrollment and end of fourth-week
Level of asthma control measured by Asthma Control Questionnaire (ACQ) - Indonesian version. Minimum value 0, maximum value 6. Higher score means worse outcome.
7 secondary outcomes
Asthma Quality of Life
Time frame: At enrollment and end of fourth-week
Bronchodilator use
Time frame: At end of fourth-week
FEV1
Time frame: At enrollment and end of fourth-week
FVC
Time frame: At enrollment and end of fourth-week
FEV1/FVC
Time frame: At enrollment and end of fourth-week
PEFR
Time frame: At enrollment and end of fourth-week
Control Pause
Time frame: At enrollment and end of fourth-week
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2025.
- Individual participant dataSharing planned: Undecided
Related trials for Breathing Techniques
Not yet recruiting
Smartphone Camera Measurement of Breathing-Related Heart Rate Variability Compared With ECG in Healthy Adults
Respiratory Sinus Arrhythmia, Heart Rate Variability
Not yet recruitingPhase 4
Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate
Asthma
Recruiting
Effect of 4-7-8 Breathing Technique on Pain and Anxiety During Electromyography in Diabetic Neuropathy
Diabetic Neuropathies, Diabetes Mellitus (Type 2)
RecruitingObservational study
Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS
ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT)
Active, not recruitingObservational study
A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.
Nasal Airway Obstruction
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Buteyko in people with Breathing Techniques and Asthma Control Level, run by Ivan Sofian Wibowo at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 17 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ivan S Wibowo, Medical Doctor (+6285647581213, ivan_sofian@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Asthma control (time frame: At enrollment and end of fourth-week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2025.