Intraocular LensNCT07025707
Comparison of Two Different Methods for Calculating Intraocular Lens Tilt and Decentration
An observational study of Intraocular Lens, run by St John of God Hospital, Vienna at 1 site in Austria.
Trial summary
Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT Read more about this study
- Who is it for?
- Ages 21 years and older
- Conditions the study is for
- Intraocular Lens
- How many people
- 15 participants
- Where
- 1 siteAustria
- Study dates
- 1 Jul 2025to 1 Sep 2025
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- Adult, Older adult
Study population: planned cataract surgery
Who may be able to join
- planned cataract surgery
- agreement to participation
Who cannot join
- Zonulolysis
- Strabismus
- Reduced Compliance
- Axial length <20 or >25 mm
- Keratokonus
- PEX
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Austria1 site, 1 recruiting
- Recruiting
Krankenhaus der Barmherzigen Brüder Wien
Vienna, State of Vienna, 1020
Konstantin Seiller-Tarbuk, Dr. med., 00431211215141, konstantin.seiller@gmail.com
About this study
Official title: Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison Between CASIA2 and CILT
Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT
Read the detailed description
This prospective observational study evaluates the agreement and reproducibility of intraocular lens (IOL) tilt and decentration measurements obtained from two different imaging modalities: the CASIA2 anterior segment swept-source optical coherence tomography (AS-SS-OCT) system and the Calculator for Intraocular Lens Tilt (CILT) software, based on standardized anterior segment image analysis.
- Conditions
- Intraocular Lens
What is being measured
The primary outcome is the main question the study is designed to answer.
Intraocular Lens Tilt (CASIA2 and CILT)
Intraocular lens (IOL) tilt, measured in degrees, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Tilt is defined as the angle between the IOL plane and the corneal vertex.
Measured: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).
Intraocular Decentration (CASIA2 and CILT)
Intraocular lens (IOL) decentration, measured in micrometers, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Decentration is defined as the distance between the IOL center and the corneal vertex.
Measured: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2025
- Study start1 Jul 2025 (estimated)
- Primary completion1 Aug 2025 (estimated)
- Study completion1 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Intraocular LensStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 15 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- St John of God Hospital, Vienna
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Michael Amon, Prim. Univ. Prof. Dr., Study chair, Hospital St. John of God
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07025707
- Sponsor's protocol ID
- 2025-0401-ST
- Status last verified
- Jun 2025
- First submitted
- 28 May 2025
- Last updated
- 17 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison Between CASIA2 and CILT
- ClinicalTrials.gov ID
- NCT07025707
- Acronym / sponsor ID
- 2025-0401-ST
- Conditions
- Intraocular Lens
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- St John of God Hospital, ViennaUniversity, hospital or other
- Study start
- 1 Jul 2025 (estimated)
- Primary completion
- 1 Aug 2025 (estimated)
- Study completion
- 1 Sep 2025 (estimated)
- First posted
- 17 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT
Detailed description
This prospective observational study evaluates the agreement and reproducibility of intraocular lens (IOL) tilt and decentration measurements obtained from two different imaging modalities: the CASIA2 anterior segment swept-source optical coherence tomography (AS-SS-OCT) system and the Calculator for Intraocular Lens Tilt (CILT) software, based on standardized anterior segment image analysis.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Day
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- planned cataract surgery
Key inclusion criteria (2 listed)
- planned cataract surgery
- agreement to participation
Key exclusion criteria (6 listed)
- Zonulolysis
- Strabismus
- Reduced Compliance
- Axial length <20 or >25 mm
- Keratokonus
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Intraocular Lens Tilt (CASIA2 and CILT)
Time frame: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).
Intraocular lens (IOL) tilt, measured in degrees, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Tilt is defined as the angle between the IOL plane and the corneal vertex.
Intraocular Decentration (CASIA2 and CILT)
Time frame: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).
Intraocular lens (IOL) decentration, measured in micrometers, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Decentration is defined as the distance between the IOL center and the corneal vertex.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Michael Amon, Prim. Univ. Prof. Dr. study chair
Hospital St. John of God
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Intraocular Lens, run by St John of God Hospital, Vienna at 1 site in Austria.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Austria. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Konstantin Seiller-Tarbuk, Dr. med. (00431211215141, konstantin.seiller@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intraocular Lens Tilt (CASIA2 and CILT) (time frame: Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2025.