Smoking, TobaccoNCT07027956
Respiratory Function and Oxygenation in Smokers and Non-smokers
An observational study of Smoking, Tobacco, run by Kirsehir Ahi Evran Universitesi at 1 site in Turkey (Türkiye).
Trial summary
This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Smoking, Tobacco
- How many people
- 42 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 28 May 2025to Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Individuals with smokers and non-smokers will be included in the study.
Who may be able to join
- According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year
- Volunteering to participate in research
- Able to walk and cooperate
- According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year
- Volunteering to participate in research
- Able to walk and cooperate
Who cannot join
- Having any cardiopulmonary disease
- Having a musculoskeletal problem that could affect the tests
- Failure to comply with tests
- Having any cardiopulmonary disease
- Having a musculoskeletal problem that could affect the tests
- Failure to comply with tests
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Kirsehir Ahi Evran University
Kırşehir
Merve Firat, +90 850 441 02 44 ext. 2490, mervefirat@ahievran.edu.tr
About this study
Official title: A Comparison of Respiratory Function, Exercise Capacity and Oxygenation Between Smokers and Non-smokers
This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.
- Conditions
- Smoking, Tobacco
- Medical subject headings
- Tobacco Smoking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Smokers | Not described | |
| Non-smokers | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Forced vital capacity
Forced vital capacity (FVC) will be assessed using spirometry.
Measured: 1st day
Forced expiratory volume in one second
Forced expiratory volume in one second (FEV1) will be assessed using spirometry
Measured: 1st day
Forced expiratory volume in one second/forced vital capacity ratio
Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.
Measured: 1st day
Peak expiratory flow
Peak expiratory flow (PEF) will be assessed using spirometry.
Measured: 1st day
Forced mid-expiratory flow
Forced mid-expiratory flow (FEF25-75) will be assessed using spirometry.
Measured: 1st day
Inspiratory muscle strength
Strength index will be evaluated.
Measured: 1st day
Exercise capacity
will be evaluated with 6 minute walk test and total distance will be recorded.
Measured: 2nd day
Intercostal muscle oxygenation
During the 6-minute walking test, oxygenation of the intercostal muscles will be evaluated with a monitor.
Measured: 2nd day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Jun 2025
- Study start28 May 2025
- Primary completionSep 2025 (estimated)
- Study completionDec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Smoking, TobaccoStudies of the same condition, open and under way.
- More trials run by Kirsehir Ahi Evran UniversitesiThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 42 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Kirsehir Ahi Evran Universitesi
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Merve Firat, Kirsehir Ahi Evran Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07027956
- Sponsor's protocol ID
- 2025-08/88
- Status last verified
- May 2025
- First submitted
- 28 May 2025
- Last updated
- 19 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Comparison of Respiratory Function, Exercise Capacity and Oxygenation Between Smokers and Non-smokers
- ClinicalTrials.gov ID
- NCT07027956
- Acronym / sponsor ID
- 2025-08/88
- Conditions
- Smoking, Tobacco
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 42 participants (estimated)
- Lead sponsor
- Kirsehir Ahi Evran UniversitesiUniversity, hospital or other
- Study start
- 28 May 2025 (actual)
- Primary completion
- Sep 2025 (estimated)
- Study completion
- Dec 2025 (estimated)
- First posted
- 19 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Smokers | – | – |
| Non-smokers | – | – |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Individuals with smokers and non-smokers will be included in the study.
Key inclusion criteria (6 listed)
- According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year
- Volunteering to participate in research
- Able to walk and cooperate
- According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year
- Volunteering to participate in research
Key exclusion criteria (6 listed)
- Having any cardiopulmonary disease
- Having a musculoskeletal problem that could affect the tests
- Failure to comply with tests
- Having any cardiopulmonary disease
- Having a musculoskeletal problem that could affect the tests
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Forced vital capacity
Time frame: 1st day
Forced vital capacity (FVC) will be assessed using spirometry.
Forced expiratory volume in one second
Time frame: 1st day
Forced expiratory volume in one second (FEV1) will be assessed using spirometry
Forced expiratory volume in one second/forced vital capacity ratio
Time frame: 1st day
Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.
Peak expiratory flow
Time frame: 1st day
Peak expiratory flow (PEF) will be assessed using spirometry.
Forced mid-expiratory flow
Time frame: 1st day
Forced mid-expiratory flow (FEF25-75) will be assessed using spirometry.
Inspiratory muscle strength
Time frame: 1st day
Strength index will be evaluated.
Exercise capacity
Time frame: 2nd day
will be evaluated with 6 minute walk test and total distance will be recorded.
Intercostal muscle oxygenation
Time frame: 2nd day
During the 6-minute walking test, oxygenation of the intercostal muscles will be evaluated with a monitor.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Jun 2025.
Related trials for Smoking, Tobacco
Active, not recruiting
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
COPD, Smoking
Enrolling by invitationObservational study
Using Smartwatches to Monitor Smoking in Real-life Situations
Smoking
Not yet recruitingObservational study
PROMETHEE: A Shared Interregional Tele-Tobacco Cessation Platform Embedded Within the IMPULSION Lung Cancer Screening Program
Smoking Cessation, Lung Cancer Screening
Recruiting
Effectiveness of Volitional Help Sheets as an Adjunct to Treatment to Promote Behavior Change: A Pilot Study on Smoking
Tobacco Dependence
Not yet recruiting
Impacto 2.0: Mobile Smoking Cessation Across Texas
Cigarette Smoking, Smoking Cessation
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Smoking, Tobacco, run by Kirsehir Ahi Evran Universitesi at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Merve Firat (+90 850 441 02 44 ext. 2490, mervefirat@ahievran.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Forced vital capacity (time frame: 1st day). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Jun 2025.