Coronary Artery DiseaseNCT07034937
Aerobic and Resistance Training in Post-CABG Patients
A study testing Combination of aerobic training (treadmill walking) and resistance training in people with Coronary Artery Disease and Post Coronary Artery Bypass Grafting, run by Universitas Padjadjaran.
Trial summary
This study investigates the effect of combined aerobic and resistance training using resistance bands on diaphragmatic excursion and pulmonary function (FVC, FEV₁, PEF) in post-CABG patients undergoing phase II cardiac rehabilitation. Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Coronary Artery Disease, Post Coronary Artery Bypass Grafting
- What is being tested?
- Combination of aerobic training (treadmill walking) and resistance training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 15 participants
- Where
- No sites listed yet
- Study dates
- 1 Aug 2025to 30 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients post-CABG surgery maximum 12 weeks after the procedure
- Age 40-65 years
- Visual and hearing health
- Ready to participate in research and sign informed consent.
Who cannot join
- Blood pressure greater than 160 mmHg for systolic and diastolic blood pressure greater than 100 mmHg
- Patients with contraindications to aerobic and resistance training, such as fractures that limit movement.
- Patients undergoing other therapies that may affect diaphragmatic muscle measurement results, such as electrical diaphragmatic stimulation.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Effect of Combination Aerobic and Resistance Training on Diaphragm Excursion Value and Pulmonary Functions in Post Coronary Artery Bypass Grafting Patients
This study investigates the effect of combined aerobic and resistance training using resistance bands on diaphragmatic excursion and pulmonary function (FVC, FEV₁, PEF) in post-CABG patients undergoing phase II cardiac rehabilitation.
Read the detailed description
This quasi-experimental study with a pretest-posttest design evaluates the impact of a 6-week structured aerobic and resistance training program using resistance bands on the diaphragm excursion and pulmonary function. Conducted at the rehabilitation polyclinics of Hasan Sadikin and Al Ihsan hospitals, this study includes post-CABG patients meeting specific inclusion criteria. Intervention is performed twice a week and includes treadmill walking and upper/lower limb resistance exercises. Outcomes will be assessed via ultrasound for diaphragm excursion and spirometry for lung function.
- Being tested
- Combination of aerobic training (treadmill walking) and resistance training
- Medical subject headings
- Coronary Artery Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Combination of aerobic training (treadmill walking) and resistance trainingOther
Combination of aerobic training (treadmill walking) and resistance training using resistance bands for deltoid, biceps, triceps, and quadriceps muscles. Conducted twice weekly for 6 weeks (12 sessions). Tools include treadmill and theraband loop bands.
| Study group | Role | What they receive |
|---|---|---|
| Aerobic and Resistance Training Group | Experimental | Not described Receives: Other: Combination of aerobic training (treadmill walking) and resistance training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Diaphragm Excursion (cm)
The vertical movement of the diaphragm during the respiratory cycle shows the function and mobility of the diaphragm in the process of pulmonary ventilation. The data obtained is expressed in cm.
Measured via ultrasound.
Measured: Baseline to Week 6
Secondary outcomes (3)
Forced Vital Capacity (FVC)
Lung function Forced Vital Capacity (FVC) is commonly assessed through spirometry and measured in liters (L) FVC: This measures the total volume of air that can be forcibly exhaled after a full inhalation. FVC values less than 80% of the predicted value are indicative of restrictive respiratory impairments, where the lungs cannot fully expand. FVC values equal to or greater than 80% are considered normal.
Measured: Baseline to Week 6
Forced Expiratory Volume in one second (FEV1)
Lung function Forced Expiratory Volume in one second (FEV1) is commonly assessed through spirometry and measured in liters (L) FEV1: This represents the air volume a person can forcefully exhale in the first second of a breath.
Measured: Baseline to Week 6
Peak Expiratory Flow (PEF)
Peak Expiratory Flow (PEF) is a spirometric parameter that measures the maximum airflow achieved at the beginning of a forced expiration, expressed in liters per second or minute. It reflects the function of the large airways and expiratory muscle strength. PEF interpretation is based on the percentage of predicted values according to age, sex, and height: ≥80% is considered normal, 60-79% indicates a mild reduction, 40-59% moderate reduction, and <40% signifies a severe reduction.
Measured: Baseline to Week 6
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jun 2025
- Study start1 Aug 2025 (estimated)
- Primary completion1 Apr 2026 (estimated)
- Study completion30 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Coronary Artery DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Single Group Assignment (Pretest-Posttest)
- Masking
- None (open label)
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universitas Padjadjaran
- Sponsor type
- University, hospital or other
- Collaborators
- Hasan Sadikin General Hospital
- Responsible party
- Sponsor
- Investigators
- Dian M Sari, MD., M.Sc., Ph.D, Principal investigator, Faculty of Medicine Universitas Padjadjaran Bandung
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07034937
- Sponsor's protocol ID
- IKFR-202506.01
- Status last verified
- Jun 2025
- First submitted
- 9 Jun 2025
- Last updated
- 24 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Combination Aerobic and Resistance Training on Diaphragm Excursion Value and Pulmonary Functions in Post Coronary Artery Bypass Grafting Patients
- ClinicalTrials.gov ID
- NCT07034937
- Acronym / sponsor ID
- IKFR-202506.01
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- Universitas PadjadjaranUniversity, hospital or other
- Collaborators
- Hasan Sadikin General Hospital
- Study start
- 1 Aug 2025 (estimated)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 30 Jul 2026 (estimated)
- First posted
- 24 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigates the effect of combined aerobic and resistance training using resistance bands on diaphragmatic excursion and pulmonary function (FVC, FEV₁, PEF) in post-CABG patients undergoing phase II cardiac rehabilitation.
Detailed description
This quasi-experimental study with a pretest-posttest design evaluates the impact of a 6-week structured aerobic and resistance training program using resistance bands on the diaphragm excursion and pulmonary function. Conducted at the rehabilitation polyclinics of Hasan Sadikin and Al Ihsan hospitals, this study includes post-CABG patients meeting specific inclusion criteria. Intervention is performed twice a week and includes treadmill walking and upper/lower limb resistance exercises. Outcomes will be assessed via ultrasound for diaphragm excursion and spirometry for lung function.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Single Group Assignment (Pretest-Posttest)
| Arm | Type | Receives |
|---|---|---|
| Aerobic and Resistance Training Group | Experimental | Other: Combination of aerobic training (treadmill walking) and resistance training |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients post-CABG surgery maximum 12 weeks after the procedure
- Age 40-65 years
- Visual and hearing health
- Ready to participate in research and sign informed consent.
Key exclusion criteria (3 listed)
- Blood pressure greater than 160 mmHg for systolic and diastolic blood pressure greater than 100 mmHg
- Patients with contraindications to aerobic and resistance training, such as fractures that limit movement.
- Patients undergoing other therapies that may affect diaphragmatic muscle measurement results, such as electrical diaphragmatic stimulation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Combination of aerobic training (treadmill walking) and resistance trainingCombination of aerobic training (treadmill walking) and resistance training using resistance bands for deltoid, biceps, triceps, and quadriceps muscles. Conducted twice weekly for 6 weeks (12 sessions). Tools include treadmill and theraband loop bands. | Other | Aerobic and Resistance Training Group |
Primary outcome
Diaphragm Excursion (cm)
Time frame: Baseline to Week 6
The vertical movement of the diaphragm during the respiratory cycle shows the function and mobility of the diaphragm in the process of pulmonary ventilation. The data obtained is expressed in cm. Measured via ultrasound.
3 secondary outcomes
Forced Vital Capacity (FVC)
Time frame: Baseline to Week 6
Forced Expiratory Volume in one second (FEV1)
Time frame: Baseline to Week 6
Peak Expiratory Flow (PEF)
Time frame: Baseline to Week 6
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Dian M Sari, MD., M.Sc., Ph.D principal investigator
Faculty of Medicine Universitas Padjadjaran Bandung
Questions about this trial
What is this clinical trial studying?
A study testing Combination of aerobic training (treadmill walking) and resistance training in people with Coronary Artery Disease and Post Coronary Artery Bypass Grafting, run by Universitas Padjadjaran.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 24 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dian M. Sari, MD., M.Sc., Ph.D (+62 812 2181 2279, dian.marta@unpad.ac.id), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Diaphragm Excursion (cm) (time frame: Baseline to Week 6). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2025.