HypertensionNCT07037329
To Determine the Effectiveness of TENS vs EMS on Hemodynamics Parameters of Hypertension
A study testing Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) in people with Hypertension, run by Superior University at 1 site in Pakistan.
Trial summary
This study aimed to evaluate the comparative effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) on hemodynamic parameters in patients with hypertension. Read more about this study
- Who is it for?
- Ages 25 to 60 years
- Conditions the study is for
- Hypertension
- What is being tested?
- Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 sitePakistan
- Study dates
- 4 Mar 2025to 30 Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- (25-60 years) including both male and female
- Patients clinically diagnosed with primary (essential) hypertension.
- Blood pressure ranging from 140/90 mmHg to 160/100 mmHg (Stage 1 to early Stage 2 hypertension).
- Participants who are not currently on intensive antihypertensive therapy or are on a stable dose of medication.
- Willingness to participate voluntarily and provide written informed consent.
- Patients who are not involved in any physical activity.
- Participants who are overweight according to normal BMI.
Who cannot join
- Secondary hypertension due to renal, endocrine, or other systemic causes. Individuals with pacemakers, implanted defibrillators, or other electronic medical devices.
- Patients with severe cardiovascular conditions, such as recent myocardial infarction, heart failure, or arrhythmias.
- History of seizure disorders or epilepsy. Cancer Patients
- Presence of skin lesions, open wounds, or infections at the site of electrode placement.
- Patients undergoing physiotherapy or electrical therapy elsewhere during the study period.
- Individuals with known neurological or musculoskeletal disorders that could interfere with EMS or TENS effectiveness
Trial locations and contacts
1 site in 1 country.
About this study
This study aimed to evaluate the comparative effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) on hemodynamic parameters in patients with hypertension. A total of 42 hypertensive patients were randomly divided into two equal groups: Group A received TENS, and Group B received EMS, over a period of four weeks. Pre- and post-treatment measurements of systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were recorded. Results showed that both TENS and EMS produced significant improvements in all parameters within their respective groups.
Read the detailed description
However, the TENS group demonstrated a greater reduction in SBP and DBP, while the EMS group showed better improvement in heart rate control. The findings suggest that both treatments are effective non-pharmacological options for managing hypertension, with TENS being more effective overall in lowering blood pressure. These modalities may offer supportive benefits in long-term hypertension management strategies.
- Conditions
- Hypertension
- Being tested
- Transcutaneous Electrical Nerve Stimulation (TENS), Electrical Muscle Stimulation (EMS)
- Medical subject headings
- Hypertension
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Transcutaneous Electrical Nerve Stimulation (TENS)Diagnostic test
TENS is a non-invasive electrotherapy technique used to manage pain and modulate physiological responses such as blood pressure. In this study, patients in Group 1 received TENS therapy as the primary intervention.
Electrical Muscle Stimulation (EMS)Diagnostic test
EMS is a form of electrotherapy that causes muscle contractions through electrical impulses delivered via surface electrodes. In this study, patients in Group 2 received EMS therapy to investigate its effect on hemodynamic parameters in individuals with hypertension.
| Study group | Role | What they receive |
|---|---|---|
| Transcutaneous Electrical Nerve Stimulation (TENS) | Experimental | Not described Receives: Diagnostic Test: Transcutaneous Electrical Nerve Stimulation (TENS) |
| Electrical Muscle Stimulation (EMS) | Experimental | Not described Receives: Diagnostic Test: Electrical Muscle Stimulation (EMS) |
What is being measured
The primary outcome is the main question the study is designed to answer.
SF-36 Health Survey (Optional for Quality of Life)
Measures general health status and quality of life 36 items grouped into 8 domains (e.g., physical functioning, general health)
Each domain scored from 0 (worst) to 100 (best)
Measured: 6 Month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jun 2025
- Study start4 Mar 2025
- Primary completion1 Jun 2025
- Study completion30 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HypertensionStudies of the same condition, open and under way.
- More trials run by Superior UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 42 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07037329
- Sponsor's protocol ID
- DPT/Batch-Fall20/1012
- Status last verified
- Jun 2025
- First submitted
- 17 Jun 2025
- Last updated
- 25 Jun 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- To Determine the Effectiveness of TENS vs EMS on Hemodynamics Parameters of Hypertension
- ClinicalTrials.gov ID
- NCT07037329
- Acronym / sponsor ID
- DPT/Batch-Fall20/1012
- Conditions
- Hypertension
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 42 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 4 Mar 2025 (actual)
- Primary completion
- 1 Jun 2025 (actual)
- Study completion
- 30 Sep 2025 (estimated)
- First posted
- 25 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to evaluate the comparative effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) on hemodynamic parameters in patients with hypertension. A total of 42 hypertensive patients were randomly divided into two equal groups: Group A received TENS, and Group B received EMS, over a period of four weeks. Pre- and post-treatment measurements of systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were recorded. Results showed that both TENS and EMS produced significant improvements in all parameters within their respective groups.
Detailed description
However, the TENS group demonstrated a greater reduction in SBP and DBP, while the EMS group showed better improvement in heart rate control. The findings suggest that both treatments are effective non-pharmacological options for managing hypertension, with TENS being more effective overall in lowering blood pressure. These modalities may offer supportive benefits in long-term hypertension management strategies.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Transcutaneous Electrical Nerve Stimulation (TENS) | Experimental | Diagnostic Test: Transcutaneous Electrical Nerve Stimulation (TENS) |
| Electrical Muscle Stimulation (EMS) | Experimental | Diagnostic Test: Electrical Muscle Stimulation (EMS) |
Who may qualify
- Ages
- 25 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- (25-60 years) including both male and female
- Patients clinically diagnosed with primary (essential) hypertension.
- Blood pressure ranging from 140/90 mmHg to 160/100 mmHg (Stage 1 to early Stage 2 hypertension).
- Participants who are not currently on intensive antihypertensive therapy or are on a stable dose of medication.
- Willingness to participate voluntarily and provide written informed consent.
Key exclusion criteria (6 listed)
- Secondary hypertension due to renal, endocrine, or other systemic causes. Individuals with pacemakers, implanted defibrillators, or other electronic medical devices.
- Patients with severe cardiovascular conditions, such as recent myocardial infarction, heart failure, or arrhythmias.
- History of seizure disorders or epilepsy. Cancer Patients
- Presence of skin lesions, open wounds, or infections at the site of electrode placement.
- Patients undergoing physiotherapy or electrical therapy elsewhere during the study period.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Transcutaneous Electrical Nerve Stimulation (TENS)TENS is a non-invasive electrotherapy technique used to manage pain and modulate physiological responses such as blood pressure. In this study, patients in Group 1 received TENS therapy as the primary intervention. | Diagnostic test | Transcutaneous Electrical Nerve Stimulation (TENS) |
| Electrical Muscle Stimulation (EMS)EMS is a form of electrotherapy that causes muscle contractions through electrical impulses delivered via surface electrodes. In this study, patients in Group 2 received EMS therapy to investigate its effect on hemodynamic parameters in individuals with hypertension. | Diagnostic test | Electrical Muscle Stimulation (EMS) |
Primary outcome
SF-36 Health Survey (Optional for Quality of Life)
Time frame: 6 Month
Measures general health status and quality of life 36 items grouped into 8 domains (e.g., physical functioning, general health) Each domain scored from 0 (worst) to 100 (best)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jun 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) in people with Hypertension, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 25 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
SF-36 Health Survey (Optional for Quality of Life) (time frame: 6 Month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jun 2025.