Injuries Related WorkMN RETAINNCT07037927
Minnesota RETAIN Phase 3
A study testing RETAIN Program in people with Injuries Related Work and Illness Related Work, run by Mayo Clinic at 1 site in United States.
Trial summary
MN RETAIN Phase 3 is a non-randomized trial to evaluate the impact of RETAIN program expansion and services on workforce retention and reduction of future workplace disability in the state of MN. The program is funded by US Department of Education (DOE). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Injuries Related Work, Illness Related Work, Disability
- What is being tested?
- RETAIN Program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,000 participants
- Where
- 1 siteUnited States
- Study dates
- 7 Jul 2025to 30 Sep 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- > 18-years-old,
- MN Resident,
- Works or intends to work in MN,
- Meets one of the following:
- Employed at the time of enrollment (must be a W2 employee) OR,
- Unemployed and in the workforce (looking for a job) referred by either:
Show all 17Show fewer
- Dislocated Worker (DW) Program,
- Healthcare provider/care team managing work restrictions
- Within 6 months of last day of work,
- Meets one of the following:
- Provider work restrictions of unable to work for at least 2 weeks
- Per healthcare team anticipated to be unable to work for at least 2 weeks
- Employer's inability to accommodate current work restrictions
- Meets one of the following:
- Diagnosis of a personal injury or illness that impacts employment (acute injury/illness or exacerbation of a chronic condition).
- Surgery or procedure anticipated within the next 4-weeks that impacts employment
- Documentation of work restrictions (i.e., written note/form documentation in electronic medical record prior to enrollment)
Who cannot join
- Does not have the capacity to give appropriate informed consent,
- Active workers' compensation claim relating to the qualifying injury or illness,
- Pending application OR Receiving Social Security Disability Insurance (SSDI) or -Supplemental Security Income (SSI),
- Self-Employed (i.e., 1099 worker)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Mayo Clinic Rochester
Rochester, Minnesota, 55905
Samantha J Westphal, MSN, RN, PHN, 507-422-6407, retain@mayo.edu
Laura Breeher, MD, MPH
About this study
Official title: Minnesota Retaining Employment and Talent After Injury/Illness Network (RETAIN) Phase 3
MN RETAIN Phase 3 is a non-randomized trial to evaluate the impact of RETAIN program expansion and services on workforce retention and reduction of future workplace disability in the state of MN. The program is funded by US Department of Education (DOE). There will be collaboration between partners to implement best practices in early intervention to support injured or ill employees in stay-at-work and return-to-work. MN RETAIN involves a partnership between Mayo Clinic and MN Department of Employment and Economic Development (DEED), and stakeholders throughout MN. MN DEED serves as the main recipient and administrator of the funding within the state with Mayo Clinic a subrecipients of the grant.
- Conditions
- Injuries Related Work, Illness Related Work, Disability
- Being tested
- RETAIN Program
- Keywords
- RETAIN, Minnesota RETAIN, MN RETAIN, Illness Recovery, Injury Recovery, Out of work help, Work Placement assistance, Job Help, Work Help, Help Keeping my job, Stay at work, Return to work
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
RETAIN ProgramOther
Facilitates early intervention strategies to support workers in staying-at or returning-to-work (SAW/RTW) after injury or illness and preventing unnecessary disability. This is done by incorporating a Return-to-Work Case Manager as a member of the healthcare clinical team who acts as a liaison for the patient and assists in coordination of referrals between healthcare and Workforce Development services. Return-to-Work Case Managers will interact with treating providers of Minnesota RETAIN participants to ensure functionally based work restrictions are documented and shared with the patient's employer.
| Study group | Role | What they receive |
|---|---|---|
| Phase 3 | Experimental | Individuals will be assigned a dedicated Minnesota RETAIN Return-to-Work Case Manager. Participants will be referred for additional career and workforce development resources when needed. Receives: Other: RETAIN Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Workers to maintain employment
Of the individuals participating, the number who achieve or maintain competitive integrated employment at the end of the enrollment period.
Measured: 6 month after enrollment
Secondary outcomes (1)
Engagement Statewide
Percentage of participants living in individual MN counties with a goal of at least 50% of counties.
Measured: 3 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2025
- Study start7 Jul 2025
- Primary completion31 Mar 2028 (estimated)
- Study completion30 Sep 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Injuries Related WorkStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Collaborators
- Minnesota Department of Employment and Economic Development, U.S. Department of Education
- Responsible party
- Principal investigator, Laura E. Breeher, Mayo Clinic
- Investigators
- Laura Breeher, M.D, M.P.H, Principal investigator, Mayo ClinicClayton Cowl, M.D, MS, Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07037927
- Sponsor's protocol ID
- 24-013097
- Other IDs
- H421F240147
- Acronym
- MN RETAIN
- Status last verified
- Oct 2025
- First submitted
- 17 Jun 2025
- Last updated
- 30 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Minnesota Retaining Employment and Talent After Injury/Illness Network (RETAIN) Phase 3
- ClinicalTrials.gov ID
- NCT07037927
- Acronym / sponsor ID
- MN RETAIN / 24-013097
- Conditions
- Injuries Related Work, Illness Related Work, Disability
- Keywords
- RETAIN, Minnesota RETAIN, MN RETAIN, Illness Recovery, Injury Recovery, Out of work help, Work Placement assistance, Job Help
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Collaborators
- Minnesota Department of Employment and Economic Development, U.S. Department of Education
- Study start
- 7 Jul 2025 (actual)
- Primary completion
- 31 Mar 2028 (estimated)
- Study completion
- 30 Sep 2029 (estimated)
- First posted
- 26 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
MN RETAIN Phase 3 is a non-randomized trial to evaluate the impact of RETAIN program expansion and services on workforce retention and reduction of future workplace disability in the state of MN. The program is funded by US Department of Education (DOE). There will be collaboration between partners to implement best practices in early intervention to support injured or ill employees in stay-at-work and return-to-work. MN RETAIN involves a partnership between Mayo Clinic and MN Department of Employment and Economic Development (DEED), and stakeholders throughout MN. MN DEED serves as the main recipient and administrator of the funding within the state with Mayo Clinic a subrecipients of the grant.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Phase 3 | Experimental | Other: RETAIN ProgramIndividuals will be assigned a dedicated Minnesota RETAIN Return-to-Work Case Manager. Participants will be referred for additional career and workforce development resources when needed. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (17 listed)
- > 18-years-old,
- MN Resident,
- Works or intends to work in MN,
- Employed at the time of enrollment (must be a W2 employee) OR,
- Unemployed and in the workforce (looking for a job) referred by either:
Key exclusion criteria (4 listed)
- Does not have the capacity to give appropriate informed consent,
- Active workers' compensation claim relating to the qualifying injury or illness,
- Pending application OR Receiving Social Security Disability Insurance (SSDI) or -Supplemental Security Income (SSI),
- Self-Employed (i.e., 1099 worker)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| RETAIN ProgramFacilitates early intervention strategies to support workers in staying-at or returning-to-work (SAW/RTW) after injury or illness and preventing unnecessary disability. This is done by incorporating a Return-to-Work Case Manager as a member of the healthcare clinical team who acts as a liaison for the patient and assists in coordination of referrals between healthcare and Workforce Development services. Return-to-Work Case Managers will interact with treating providers of Minnesota RETAIN participants to ensure functionally based work restrictions are documented and shared with the patient's employer. | Other | Phase 3 |
Primary outcome
Workers to maintain employment
Time frame: 6 month after enrollment
Of the individuals participating, the number who achieve or maintain competitive integrated employment at the end of the enrollment period.
1 secondary outcome
Engagement Statewide
Time frame: 3 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Oct 2025.
- Individual participant dataSharing planned: No
Related trials for Injuries Related Work
Recruiting
Cognitive Control Training for Extinction in PTSD
Post-Traumatic Stress Disorders, Stress Disorders, Traumatic
Not yet recruiting
Cohesive Bandage Fixation of Pulse Oximeter Probes and Skin Condition in Preterm Neonates
Skin Injury, Premature Birth
Recruiting
Consecutive Occupational Heat Exposure With and Without Overnight Cooling
Body Temperature Changes, Heat Stress
Not yet recruiting
Transcutaneous Vagus Nerve Stimulation for Attention and Memory
Traumatic Brain Injury (TBI) Patients
Recruiting
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Schizophrenia, Bipolar Disorder
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Laura Breeher, M.D, M.P.H principal investigator
Mayo Clinic
Clayton Cowl, M.D, MS principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing RETAIN Program in people with Injuries Related Work and Illness Related Work, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 17 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 30 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Samantha Westphal, MSN, RN, PHN (507-422-6407, westphal.samantha@mayo.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Workers to maintain employment (time frame: 6 month after enrollment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Oct 2025.