Vaping BehaviorsNCT07038317
A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status
A study testing Intervention in people with Vaping Behaviors and Message Exposure, run by University of Hawaii at 1 site in United States.
Trial summary
The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors. The main questions it aims to answer are: 1. Read more about this study
- Who is it for?
- Ages 18 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Vaping Behaviors, Message Exposure, Young Adults
- What is being tested?
- Intervention
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 120 participants
- Where
- 1 siteUnited States
- Study dates
- 29 Jul 2026to 31 Jan 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- 18-24 years old
- Fluent in English
- Not currently using tobacco products other than e-cigarettes at the time of enrollment
- Have a mobile phone to send and receive text messages
Who cannot join
- Age below 18 or above 24
- Not being fluent in English
- Currently using tobacco products other than e-cigarettes
- Not having a mobile phone
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
University of Hawaii Cancer Center
Honolulu, Hawaii, 96822
About this study
Official title: Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-vapers
The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors. The main questions it aims to answer are:
- Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the current vaper group influence vaping cessation among young adults who vape daily?
- Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the non-vaper group influence vaping initiation among young adults who are susceptible to vaping? Participants will be randomly assigned to either the treatment (receiving messages tailored to one's vaping status) or the control (receiving non-tobacco messages) condition and receive SMS three times per week over the course of 6 months. They will complete self-report assessment and show salivary cotinine results for nicotine testing at 4 timepoints.
- Conditions
- Vaping Behaviors, Message Exposure, Young Adults
- Being tested
- Intervention, Control
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
InterventionOther
Intervention involves e-cigarette education messages tailored to participants' vaping status that will be sent out in SMS via text messaging three times per week over the course of 6 months.
ControlOther
Participants will receive non-tobacco messages (messages about sun safety) three times per week over the course of 6 months.
| Study group | Role | What they receive |
|---|---|---|
| Treatment | Experimental | Participants in the treatment arm will receive e-cigarette education messages with source and sidedness optimized to one's vaping status. Receives: Other: Intervention |
| Control | Placebo comparator | Participants in the control arm will receive messages about sun safety. Receives: Other: Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Self-reported vaping
Past-30-day vaping (yes/no) will be assessed
Measured: Baseline, six-month
Biochemical confirmation of vaping
Salivary cotinine for nicotine testing
Measured: Baseline, one-month, three-month, six-month
Secondary outcomes (5)
Harm perceptions
Participants will be asked to indicate the extent to which they think vaping nicotine (using e-cigarettes) is… safe, containing flavors that are safe to use, containing dangerous chemical, harmful to health on a scale from 1 (strongly disagree) to 5 (strongly agree).
Measured: Baseline, one-month, three-month, six-month
Message perceptions
Participants will be asked to indicate the extent to which they think the message was worth remembering, grabbed their attention, powerful, convincing, meaningful on a scale from 1 (strongly disagree) to 5 (strongly agree).
Measured: One-month, three-month, six-month
Message liking
Participants will be asked to indicate the extent to which they liked the message they saw on a scale from 1 (dislike very much) to 5 (like very much).
Measured: One-month, three-month, six-month
Number of days of past-30-day e-cigarette use
Participants will be asked to report the number of days in the past 30 days (between 0 to 30) they used an e-cigarette.
Measured: From enrollment to the end of study at 24 weeks.
E-cigarette accessibility
Participants will be assessed how they usually purchase e-cigarettes for themselves with categorical response options of…in person, from the Internet, by phone, don't buy their own. This question will only be asked if response indicates participants are between the ages of 18 and 20 AND have used e-cigarettes more than 0 days in the past 30 days.
Measured: Baseline, one-month, three-month, six-month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2025
- Study start29 Jul 2026
- Primary completion30 Dec 2027 (estimated)
- Study completion31 Jan 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vaping BehaviorsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Hawaii
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Principal investigator, Donghee Nicole Lee, University of Hawaii
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07038317
- Sponsor's protocol ID
- Lee-2025-1 (4R00CA281094)
- Status last verified
- Oct 2026
- First submitted
- 10 Jun 2025
- Last updated
- 7 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified participants dataset will be shared.
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-vapers
- ClinicalTrials.gov ID
- NCT07038317
- Acronym / sponsor ID
- Lee-2025-1 (4R00CA281094)
- Conditions
- Vaping Behaviors, Message Exposure, Young Adults
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- University of HawaiiUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 29 Jul 2026 (actual)
- Primary completion
- 30 Dec 2027 (estimated)
- Study completion
- 31 Jan 2028 (estimated)
- First posted
- 26 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors. The main questions it aims to answer are:
- Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the current vaper group influence vaping cessation among young adults who vape daily?
- Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the non-vaper group influence vaping initiation among young adults who are susceptible to vaping? Participants will be randomly assigned to either the treatment (receiving messages tailored to one's vaping status) or the control (receiving non-tobacco messages) condition and receive SMS three times per week over the course of 6 months. They will complete self-report assessment and show salivary cotinine results for nicotine testing at 4 timepoints.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Treatment | Experimental | Other: InterventionParticipants in the treatment arm will receive e-cigarette education messages with source and sidedness optimized to one's vaping status. |
| Control | Placebo comparator | Other: ControlParticipants in the control arm will receive messages about sun safety. |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- 18-24 years old
- Fluent in English
- Not currently using tobacco products other than e-cigarettes at the time of enrollment
- Have a mobile phone to send and receive text messages
Key exclusion criteria (4 listed)
- Age below 18 or above 24
- Not being fluent in English
- Currently using tobacco products other than e-cigarettes
- Not having a mobile phone
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| InterventionIntervention involves e-cigarette education messages tailored to participants' vaping status that will be sent out in SMS via text messaging three times per week over the course of 6 months. | Other | Treatment |
| ControlParticipants will receive non-tobacco messages (messages about sun safety) three times per week over the course of 6 months. | Other | Control |
Primary outcome
Self-reported vaping
Time frame: Baseline, six-month
Past-30-day vaping (yes/no) will be assessed
Biochemical confirmation of vaping
Time frame: Baseline, one-month, three-month, six-month
Salivary cotinine for nicotine testing
5 secondary outcomes
Harm perceptions
Time frame: Baseline, one-month, three-month, six-month
Message perceptions
Time frame: One-month, three-month, six-month
Message liking
Time frame: One-month, three-month, six-month
Number of days of past-30-day e-cigarette use
Time frame: From enrollment to the end of study at 24 weeks.
E-cigarette accessibility
Time frame: Baseline, one-month, three-month, six-month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2026.
- Individual participant dataSharing planned: Yes. De-identified participants dataset will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Intervention in people with Vaping Behaviors and Message Exposure, run by University of Hawaii at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 7 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self-reported vaping (time frame: Baseline, six-month). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2026.