Overactive Bladder SyndromeNCT07044778
Prevalence And Risk Factors of Overactive Bladder Syndrome Among Egyptian Medical Students, and Their Impact On Health-Related Quality Of Life
An observational study of Overactive Bladder Syndrome, run by Zagazig University at 1 site in Egypt.
Trial summary
Overactive bladder (OAB) is defined as sudden, urgent desire to urinate (urgency) accompanied by frequency and nocturia, with or without urgent urinary incontinence in the absence of urinary tract infection (UTI). Read more about this study
- Who is it for?
- Ages 18 to 27 yearsHealthy volunteers can take part
- Conditions the study is for
- Overactive Bladder Syndrome
- What is being tested?
- Questionnaire
- How many people
- 1,003 participants
- Where
- 1 siteEgypt
- Study dates
- 15 May 2025to 25 Jun 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 27 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Egyptian medical students who have access to social media
Who may be able to join
- Medical student studying human medicine in Egypt
- Their age ranges from 18 to 27 years old
- Egyptian person
Who cannot join
- Incomplete data
- Wrong data in the questionnaire
- Students refuse to participate
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Prevalence And Risk Factor Of Overactive Bladder Syndrome Among Egyptian Medical Students And Their Impact On Health-Related Quality Of Life, Cross-Sectional Study
Overactive bladder (OAB) is defined as sudden, urgent desire to urinate (urgency) accompanied by frequency and nocturia, with or without urgent urinary incontinence in the absence of urinary tract infection (UTI). This condition can significantly decrease the quality of life of these patients, as it can humiliate their actions, affect their relationships with others, and it can also affect their productivity. Due to all these effects, several studies have linked the increase in overactive bladder symptoms with an increase in anxiety and depression rates. A recent cross-sectional study in the UK and Sweden, called EpiLUTS, included 10,000 participants. the investigators found a statistically significant increase in anxiety and depression rates among both men and women in both the UK and Sweden, with a slight increase in men than women On the other hand, there are several risk factors such as overweight, smoking, diabetes, and hypertension. In a previous cross-sectional study in Jordan, the investigators found a correlation between an increase in risk factors such as age group, history of trauma, stressful life, and medication, and overactive bladder symptoms among medical students.
Several studies have assessed the prevalence of overactive bladder among different population age groups, ethnicities, or genders with varying results. It was rated to be 11.8% in a multicenter cross-sectional study including several countries in Canada and Europe (Germany, Italy, Sweden, and the UK), while in the USA it was estimated to be 16%. All these studies were conducted on the general population; however, in China, it was about 6% among university students.
Read more
In the Arab world, several cross-sectional studies have also assessed the prevalence of overactive bladder, including students, and its effect on the quality of life. Hajjar 2022 assessed its prevalence among Lebanese female nulliparae university students. They showed that nocturia and frequency were the most common symptoms that bothered students. the investigators also found a statistical correlation between smoking, drinking coffee, or tea, and increased symptoms. Also, drinking soft drinks was associated with an increase in urinary leakage. Additionally, Abuorouq 2024 and Shawahna 2021 conducted Cross-sectional studies were conducted on medical students in Jordan and Palestine, respectively. They reported a prevalence of 44.5% and 54.1%, respectively. Shawahna 2021 reported a statistically significant correlation between gender or stressful life and a decrease in quality of life.
Rational In Egypt, the prevalence of overactive bladder is underestimated. A single previous multinational cross-sectional study across several Arab countries, including Egypt, was conducted. was conducted in Egypt, Algeria, Jordan, and Lebanon among women. the investigators reported a prevalence of 57.5% among Egyptian women.
Since this study, no study has been conducted to further assess its prevalence in different age or gender groups in Egypt. Taking into consideration the stressful life of medical students in Egypt, and several life risk factors they face, the investigators will conduct this cross-sectional study.
- Conditions
- Overactive Bladder Syndrome
- Being tested
- Questionnaire
- Keywords
- overactive bladder, Prevalence, medical students, quality of life
- Medical subject headings
- Urinary Bladder, Overactive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
QuestionnaireOther
An online Questionnaire designed by Google Forms will be shared on social media for medical students in Egypt to fill
What is being measured
The primary outcome is the main question the study is designed to answer.
Overactive Bladder Syndrome prevalence
We will use OAB-q SF for diagnosing symptoms bother. It is a 6-item questionnaire to diagnose symptoms bother; each question has 6 Likert scale answers. A score of 1 to 6 for each question will form a scale of 6 to 36. An increase in score indicates an increase in symptoms bother
Measured: through study completion, an average of 1 month
Secondary outcomes (1)
Quality of life affected by OAB
Using the second part of the OAB-q SF (HRQL). This is a 13 Likert scale questionnaire. each question has 6 answers to assess its quality of life. A score range from 13 to 78, with a decrease indicating a decrease in the quality of life
Measured: through study completion, an average of 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2025
- Study start15 May 2025
- Primary completion15 Jun 2025
- Study completion25 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Overactive Bladder SyndromeStudies of the same condition, open and under way.
- More trials run by Zagazig UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 1,003 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07044778
- Sponsor's protocol ID
- ZU-IRB # 1328 /18-May-2025
- Status last verified
- May 2025
- First submitted
- 24 May 2025
- Last updated
- 3 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Coyne KS, Payne C, Bhattacharyya SK, Revicki DA, Thompson C, Corey R, Hunt TL. The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health. 2004 Jul-Aug;7(4):455-63. doi: 10.1111/j.1524-4733.2004.74008.x.
PubMed 15449637Abuorouq S, Al-Zubi M, Al-Ali AM, Aloqaily LH, Talafha MA, Migdadi AM, Serhan HA. The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study. BMC Urol. 2024 Jan 3;24(1):7. doi: 10.1186/s12894-023-01394-4.
PubMed 38172746Mohamed AF, Hagag AM, Elgamal MM, Elshaikh IE, Abdellatif AH, Ali A, Eliwa AM. Prevalence and risk factors of overactive bladder syndrome among Egyptian medical students, and its impact on health-related quality of life, cross-sectional study. Sci Rep. 2026 May 27;16(1):16437. doi: 10.1038/s41598-026-53181-4.
PubMed 42204195
Study at a glance
From the registry record, last updated by the sponsor on 3 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence And Risk Factor Of Overactive Bladder Syndrome Among Egyptian Medical Students And Their Impact On Health-Related Quality Of Life, Cross-Sectional Study
- ClinicalTrials.gov ID
- NCT07044778
- Acronym / sponsor ID
- ZU-IRB # 1328 /18-May-2025
- Conditions
- Overactive Bladder Syndrome
- Keywords
- overactive bladder, Prevalence, medical students, quality of life
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,003 participants (actual)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 15 May 2025 (actual)
- Primary completion
- 15 Jun 2025 (actual)
- Study completion
- 25 Jun 2025 (actual)
- First posted
- 1 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Overactive bladder (OAB) is defined as sudden, urgent desire to urinate (urgency) accompanied by frequency and nocturia, with or without urgent urinary incontinence in the absence of urinary tract infection (UTI). This condition can significantly decrease the quality of life of these patients, as it can humiliate their actions, affect their relationships with others, and it can also affect their productivity. Due to all these effects, several studies have linked the increase in overactive bladder symptoms with an increase in anxiety and depression rates. A recent cross-sectional study in the UK and Sweden, called EpiLUTS, included 10,000 participants. the investigators found a statistically significant increase in anxiety and depression rates among both men and women in both the UK and Sweden, with a slight increase in men than women On the other hand, there are several risk factors such as overweight, smoking, diabetes, and hypertension. In a previous cross-sectional study in Jordan, the investigators found a correlation between an increase in risk factors such as age group, history of trauma, stressful life, and medication, and overactive bladder symptoms among medical students.
Several studies have assessed the prevalence of overactive bladder among different population age groups, ethnicities, or genders with varying results. It was rated to be 11.8% in a multicenter cross-sectional study including several countries in Canada and Europe (Germany, Italy, Sweden, and the UK), while in the USA it was estimated to be 16%. All these studies were conducted on the general population; however, in China, it was about 6% among university students.
In the Arab world, several cross-sectional studies have also assessed the prevalence of overactive bladder, including students, and its effect on the quality of life. Hajjar 2022 assessed its prevalence among Lebanese female nulliparae university students. They showed that nocturia and frequency were the most common symptoms that bothered students. the investigators also found a statistical correlation between smoking, drinking coffee, or tea, and increased symptoms. Also, drinking soft drinks was associated with an increase in urinary leakage. Additionally, Abuorouq 2024 and Shawahna 2021 conducted Cross-sectional studies were conducted on medical students in Jordan and Palestine, respectively. They reported a prevalence of 44.5% and 54.1%, respectively. Shawahna 2021 reported a statistically significant correlation between gender or stressful life and a decrease in quality of life.
Rational In Egypt, the prevalence of overactive bladder is underestimated. A single previous multinational cross-sectional study across several Arab countries, including Egypt, was conducted. was conducted in Egypt, Algeria, Jordan, and Lebanon among women. the investigators reported a prevalence of 57.5% among Egyptian women.
Since this study, no study has been conducted to further assess its prevalence in different age or gender groups in Egypt. Taking into consideration the stressful life of medical students in Egypt, and several life risk factors they face, the investigators will conduct this cross-sectional study.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 to 27 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Egyptian medical students who have access to social media
Key inclusion criteria (3 listed)
- Medical student studying human medicine in Egypt
- Their age ranges from 18 to 27 years old
- Egyptian person
Key exclusion criteria (3 listed)
- Incomplete data
- Wrong data in the questionnaire
- Students refuse to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| QuestionnaireAn online Questionnaire designed by Google Forms will be shared on social media for medical students in Egypt to fill | Other | – |
Primary outcome
Overactive Bladder Syndrome prevalence
Time frame: through study completion, an average of 1 month
We will use OAB-q SF for diagnosing symptoms bother. It is a 6-item questionnaire to diagnose symptoms bother; each question has 6 Likert scale answers. A score of 1 to 6 for each question will form a scale of 6 to 36. An increase in score indicates an increase in symptoms bother
1 secondary outcome
Quality of life affected by OAB
Time frame: through study completion, an average of 1 month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jul 2025.
- Results publication: PubMed 15449637Coyne KS, Payne C, Bhattacharyya SK, Revicki DA, Thompson C, Corey R, Hunt TL. The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health. 2004 Jul-Aug;7(4):455-63. doi: 10.1111/j.1524-4733.2004.74008.x.
- Results publication: PubMed 38172746Abuorouq S, Al-Zubi M, Al-Ali AM, Aloqaily LH, Talafha MA, Migdadi AM, Serhan HA. The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study. BMC Urol. 2024 Jan 3;24(1):7. doi: 10.1186/s12894-023-01394-4.
- Derived from this study: PubMed 42204195Mohamed AF, Hagag AM, Elgamal MM, Elshaikh IE, Abdellatif AH, Ali A, Eliwa AM. Prevalence and risk factors of overactive bladder syndrome among Egyptian medical students, and its impact on health-related quality of life, cross-sectional study. Sci Rep. 2026 May 27;16(1):16437. doi: 10.1038/s41598-026-53181-4.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Overactive Bladder Syndrome, run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overactive Bladder Syndrome prevalence (time frame: through study completion, an average of 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07044778, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jul 2025.