Cirrhosis, LiverNCT07051369
Frequency of Portal Hypertension Among Patient With Cirrhotic Liver With Ultrasound
An observational study of Cirrhosis, Liver, run by Superior University at 1 site in Pakistan.
Trial summary
Portal hypertension is a common and serious complication of liver cirrhosis, often leading to life-threatening conditions such as variceal bleeding, ascites, and hepatic encephalopathy. Read more about this study
- Who is it for?
- Ages 20 to 60 years
- Conditions the study is for
- Cirrhosis, Liver
- What is being tested?
- Portal Hypertension diagnostics
- How many people
- 150 participants
- Where
- 1 sitePakistan
- Study dates
- 17 Mar 2025to 28 Feb 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 60 years
- All sexes
- No healthy volunteers
- Adult
Study population: his study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.A cross-sectional study will be conducted at Sheikh Zaid Medical College and Hospital, Rahim Yar Khan,
Who may be able to join
- Patients with a history of chronic liver disease (CLD) will be included.
- Both male and female patients will be included.
Who cannot join
- Non-cirrhotic liver patients
- Non-cooperative patients.Patients who do not provide written informed consent
Trial locations and contacts
1 site in 1 country.
About this study
Portal hypertension is a common and serious complication of liver cirrhosis, often leading to life-threatening conditions such as variceal bleeding, ascites, and hepatic encephalopathy.
Read the detailed description
Early detection and management are crucial for improving patient outcomes. While invasive methods such as hepatic venous pressure gradient (HVPG) measurement are the gold standard for diagnosis, they are costly and not widely available. Ultrasound, particularly Doppler imaging, offers a non-invasive, cost- effective alternative for assessing portal hypertension.This study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.
- Conditions
- Cirrhosis, Liver
- Being tested
- Portal Hypertension diagnostics
- Medical subject headings
- Liver Cirrhosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Portal Hypertension diagnosticsDiagnostic test
his study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.A cross-sectional study will be conducted at Sheikh Zaid Medical College and Hospital, Rahim Yar Khan,
What is being measured
The primary outcome is the main question the study is designed to answer.
Ultrasound Parameter Response
this questioner will take the data from the ultrasound values having liver chirosis
Measured: 12 Months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jul 2025
- Study start17 Mar 2025
- Primary completion1 Sep 2025 (estimated)
- Study completion28 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cirrhosis, LiverStudies of the same condition, open and under way.
- More trials run by Superior UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 150 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07051369
- Sponsor's protocol ID
- MSAHSW/Batch-Fall23/920
- Status last verified
- Jun 2025
- First submitted
- 26 Jun 2025
- Last updated
- 4 Jul 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Frequency of Portal Hypertension Among Patient With Cirrhotic Liver With Ultrasound
- ClinicalTrials.gov ID
- NCT07051369
- Acronym / sponsor ID
- MSAHSW/Batch-Fall23/920
- Conditions
- Cirrhosis, Liver
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 150 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 17 Mar 2025 (actual)
- Primary completion
- 1 Sep 2025 (estimated)
- Study completion
- 28 Feb 2026 (estimated)
- First posted
- 4 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Portal hypertension is a common and serious complication of liver cirrhosis, often leading to life-threatening conditions such as variceal bleeding, ascites, and hepatic encephalopathy.
Detailed description
Early detection and management are crucial for improving patient outcomes. While invasive methods such as hepatic venous pressure gradient (HVPG) measurement are the gold standard for diagnosis, they are costly and not widely available. Ultrasound, particularly Doppler imaging, offers a non-invasive, cost- effective alternative for assessing portal hypertension.This study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
Who may qualify
- Ages
- 20 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- his study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.A cross-sectional study will be conducted at Sheikh Zaid Medical College and Hospital, Rahim Yar Khan,
Key inclusion criteria (2 listed)
- Patients with a history of chronic liver disease (CLD) will be included.
- Both male and female patients will be included.
Key exclusion criteria (2 listed)
- Non-cirrhotic liver patients
- Non-cooperative patients.Patients who do not provide written informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Portal Hypertension diagnosticshis study aims to determine the frequency of portal hypertension among patients with cirrhotic liver using ultrasound.A cross-sectional study will be conducted at Sheikh Zaid Medical College and Hospital, Rahim Yar Khan, | Diagnostic test | – |
Primary outcome
Ultrasound Parameter Response
Time frame: 12 Months
this questioner will take the data from the ultrasound values having liver chirosis
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cirrhosis, Liver, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 4 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Ultrasound Parameter Response (time frame: 12 Months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Jul 2025.