Accident, TrafficNCT07051395
Correlation Between Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan
An observational study of Accident, Traffic, run by Superior University at 1 site in Pakistan.
Trial summary
Trauma-induced coagulopathy (TIC), also known as acute traumatic coagulopathy (ATC), is a common condition in patients with severe trauma, particularly in road traffic accident (RTA) victims. Coagulopathy is often associated with high mortality rates and poor outcomes in trauma patients. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Accident, Traffic
- What is being tested?
- Road Traffic Accidents Patient
- How many people
- 230 participants
- Where
- 1 sitePakistan
- Study dates
- 17 Mar 2025to 1 Mar 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: To assess the correlation between coagulation profiles and injury severity in trauma patients, with a focus on the prevalence of trauma-induced coagulopathy (TIC) in road traffic accident (RTA) cases at a tertiary care hospital in Dera Ismail Khan. Methods: A cross-sectional observational study will be conducted in the Accident \& Emergency (A\&E) Department and Trauma Center of DHQ Hospital, Dera Ismail Khan. The study population includes patients aged 18 years and above, with moderate to severe injuries (Injury Severity Score ≥ 15),
Who may be able to join
- Patients with moderate to severe injuries (Injury Severity Score>15).
- All Patients will be admitted in Accident and Emergency Center after the accident.
Who cannot join
- Patients with Mild injury and score <15.
- Patients with pre-existing coagulation disorders (e.g., hemophilia).
- Patients on anticoagulant therapy prior to admission.
- Patients with incomplete medical records or insufficient blood samples.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Mufti Mehmood Memorial Teaching Hospital
Dera Ismāīl Khān, Khyber Pakhtunkhwa
About this study
Trauma-induced coagulopathy (TIC), also known as acute traumatic coagulopathy (ATC), is a common condition in patients with severe trauma, particularly in road traffic accident (RTA) victims. Coagulopathy is often associated with high mortality rates and poor outcomes in trauma patients.
Read the detailed description
The study explores the correlation between coagulation profiles and the severity of injuries in patients admitted to a tertiary care hospital following RTAs.
- Conditions
- Accident, Traffic
- Being tested
- Road Traffic Accidents Patient
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Road Traffic Accidents PatientDiagnostic test
Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan
What is being measured
The primary outcome is the main question the study is designed to answer.
Self Admisnistred questioner
A Self Admisnistred questioner is used to collect the data and details of the accident
Measured: 12 Months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jul 2025
- Study start17 Mar 2025
- Primary completion1 Sep 2025 (estimated)
- Study completion1 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Accident, TrafficStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 230 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07051395
- Sponsor's protocol ID
- MSAHSW/Batch-Fall23/922
- Status last verified
- Jun 2025
- First submitted
- 26 Jun 2025
- Last updated
- 4 Jul 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan
- ClinicalTrials.gov ID
- NCT07051395
- Acronym / sponsor ID
- MSAHSW/Batch-Fall23/922
- Conditions
- Accident, Traffic
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 230 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 17 Mar 2025 (actual)
- Primary completion
- 1 Sep 2025 (estimated)
- Study completion
- 1 Mar 2026 (estimated)
- First posted
- 4 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Trauma-induced coagulopathy (TIC), also known as acute traumatic coagulopathy (ATC), is a common condition in patients with severe trauma, particularly in road traffic accident (RTA) victims. Coagulopathy is often associated with high mortality rates and poor outcomes in trauma patients.
Detailed description
The study explores the correlation between coagulation profiles and the severity of injuries in patients admitted to a tertiary care hospital following RTAs.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- To assess the correlation between coagulation profiles and injury severity in trauma patients, with a focus on the prevalence of trauma-induced coagulopathy (TIC) in road traffic accident (RTA) cases at a tertiary care hospital in Dera Ismail Khan. Methods: A cross-sectional observational study will be conducted in the Accident \& Emergency (A\&E) Department and Trauma Center of DHQ Hospital, Dera Ismail Khan. The study population includes patients aged 18 years and above, with moderate to severe injuries (Injury Severity Score ≥ 15),
Key inclusion criteria (2 listed)
- Patients with moderate to severe injuries (Injury Severity Score>15).
- All Patients will be admitted in Accident and Emergency Center after the accident.
Key exclusion criteria (4 listed)
- Patients with Mild injury and score <15.
- Patients with pre-existing coagulation disorders (e.g., hemophilia).
- Patients on anticoagulant therapy prior to admission.
- Patients with incomplete medical records or insufficient blood samples.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Road Traffic Accidents PatientCoagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan | Diagnostic test | – |
Primary outcome
Self Admisnistred questioner
Time frame: 12 Months
A Self Admisnistred questioner is used to collect the data and details of the accident
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Jul 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Accident, Traffic, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 4 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self Admisnistred questioner (time frame: 12 Months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Jul 2025.