Posterior Mandible With Deficient Ridge HeightNCT07054658
Evaluation of Allogenic Bone Ring Graft With Simultaneous Implant Placement for Vertical Ridge Augmentation
A study testing Allogenic Bone Ring Graft With Simultaneous Implant Placement in people with Posterior Mandible With Deficient Ridge Height, run by Tanta University at 1 site in Egypt.
Trial summary
This clinical trial aimed to evaluate the effectiveness of vertical ridge augmentation using customized allogenic bone ring grafts with simultaneous dental implant placement in the posterior mandible. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Posterior Mandible With Deficient Ridge Height
- What is being tested?
- Allogenic Bone Ring Graft With Simultaneous Implant Placement
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteEgypt
- Study dates
- 23 May 2024to 27 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Participants with vertical alveolar ridge atrophy in the posterior mandible who are motivated, cooperative, and have good oral hygiene.
- Minimum of 7 mm remaining bone height from the crest of the alveolar ridge to the inferior alveolar canal.
- Patients with adequate remaining interarch space
Who cannot join
- Prior local radiation therapy.
- Soft and hard tissue pathology at the operation site.
- Systemic diseases that might affect bone healing and osseointegration (e.g., uncontrolled diabetes)..
- smokers who consume 20 or more cigarettes per day.
- patients on anti-resorptive drugs (eg: bisphosphonates and denosumab).
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Dentistry, Tanta University
Tanta, Gharbia Governorate, 31527
About this study
This clinical trial aimed to evaluate the effectiveness of vertical ridge augmentation using customized allogenic bone ring grafts with simultaneous dental implant placement in the posterior mandible. The procedure is designed to address vertical bone deficiencies without the need for autogenous bone harvesting, thereby reducing patient morbidity and surgical complexity. The study assessed clinical outcomes including bone gain, implant stability, and over a 6-month period and inflammation, infection, pain and neurosensory changes where assessed for 4 weeks.
Read the detailed description
This study investigated the clinical outcomes of vertical ridge augmentation using allogenic bone rings in combination with simultaneous implant placement for the treatment of posterior mandibular bone defects. Traditional ridge augmentation techniques often require two-stage surgeries and autogenous bone harvesting, which may increase patient morbidity and prolong healing. In contrast, the allogenic bone ring technique provides a one-stage approach by allowing vertical augmentation and implant placement to be performed simultaneously.
The study was designed as a prospective, single-arm clinical trial. Eligible patients aged 18 years or older, presenting with vertical bone deficiencies in the posterior mandible, were recruited from the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University. The primary outcome was vertical bone gain measured radiographically at 6 months postoperatively. Secondary outcomes included implant stability (measured by IST), soft tissue healing, and postoperative complications. Patients were followed clinically and radiographically to evaluate the success of the grafting procedure and implant integration.
- Being tested
- Allogenic Bone Ring Graft With Simultaneous Implant Placement
- Keywords
- vertical ridge augmentation, bone ring technique
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Allogenic Bone Ring Graft With Simultaneous Implant PlacementProcedure or surgery
A surgical procedure involving vertical ridge augmentation using an allogenic bone ring combined with simultaneous dental implant placement in the posterior mandible. The technique allows one-stage treatment of vertical bone defects without the need for autogenous bone harvesting.
| Study group | Role | What they receive |
|---|---|---|
| Allogenic Bone Ring With Simultaneous Implant Placemen | Experimental | Patients received vertical ridge augmentation using a customized allogenic bone ring graft with simultaneous dental implant placement in the posterior mandible Receives: Procedure: Allogenic Bone Ring Graft With Simultaneous Implant Placement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Vertical Bone Gain in mm
The vertical bone gain was measured radiographically using CBCT imaging to evaluate the effectiveness of the allogenic bone ring graft in augmenting vertical bone height in the posterior mandible
Measured: 6 months postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jul 2025
- Study start23 May 2024
- Primary completion31 Jan 2025
- Study completion27 Feb 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Posterior Mandible With Deficient Ridge HeightStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Participants in this study received an allogenic bone ring graft for vertical ridge augmentation, with simultaneous dental implant placement
- Masking
- None (open label)
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ibrahim Taha Hussein, Tanta University
- Investigators
- Ibrahim T Hussein, Principal investigator, Faculty of Dentistry, Tanta University, EgyptRafic R Beder, Principal investigator, Faculty of Dentistry, Tanta University, EgyptKhaled A Saad, Principal investigator, Faculty of Dentistry, Tanta University, EgyptMaram N Breshah, Principal investigator, Faculty of Dentistry, Tanta University, Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07054658
- Sponsor's protocol ID
- RD-3-24-2166
- Status last verified
- Jul 2025
- First submitted
- 27 Jun 2025
- Last updated
- 22 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Hussein IT, Beder RR, Saad KA, Breshah MN. Evaluation of allogenic bone ring graft with simultaneous implant placement for vertical ridge augmentation. Oral Maxillofac Surg. 2025 Dec 1;30(1):4. doi: 10.1007/s10006-025-01487-4.
PubMed 41320709
Study at a glance
From the registry record, last updated by the sponsor on 22 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Allogenic Bone Ring Graft With Simultaneous Implant Placement for Vertical Ridge Augmentation
- ClinicalTrials.gov ID
- NCT07054658
- Acronym / sponsor ID
- RD-3-24-2166
- Keywords
- vertical ridge augmentation, bone ring technique
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 10 participants (actual)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 23 May 2024 (actual)
- Primary completion
- 31 Jan 2025 (actual)
- Study completion
- 27 Feb 2025 (actual)
- First posted
- 8 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial aimed to evaluate the effectiveness of vertical ridge augmentation using customized allogenic bone ring grafts with simultaneous dental implant placement in the posterior mandible. The procedure is designed to address vertical bone deficiencies without the need for autogenous bone harvesting, thereby reducing patient morbidity and surgical complexity. The study assessed clinical outcomes including bone gain, implant stability, and over a 6-month period and inflammation, infection, pain and neurosensory changes where assessed for 4 weeks.
Detailed description
This study investigated the clinical outcomes of vertical ridge augmentation using allogenic bone rings in combination with simultaneous implant placement for the treatment of posterior mandibular bone defects. Traditional ridge augmentation techniques often require two-stage surgeries and autogenous bone harvesting, which may increase patient morbidity and prolong healing. In contrast, the allogenic bone ring technique provides a one-stage approach by allowing vertical augmentation and implant placement to be performed simultaneously.
The study was designed as a prospective, single-arm clinical trial. Eligible patients aged 18 years or older, presenting with vertical bone deficiencies in the posterior mandible, were recruited from the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University. The primary outcome was vertical bone gain measured radiographically at 6 months postoperatively. Secondary outcomes included implant stability (measured by IST), soft tissue healing, and postoperative complications. Patients were followed clinically and radiographically to evaluate the success of the grafting procedure and implant integration.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Participants in this study received an allogenic bone ring graft for vertical ridge augmentation, with simultaneous dental implant placement
| Arm | Type | Receives |
|---|---|---|
| Allogenic Bone Ring With Simultaneous Implant Placemen | Experimental | Procedure: Allogenic Bone Ring Graft With Simultaneous Implant PlacementPatients received vertical ridge augmentation using a customized allogenic bone ring graft with simultaneous dental implant placement in the posterior mandible |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Participants with vertical alveolar ridge atrophy in the posterior mandible who are motivated, cooperative, and have good oral hygiene.
- Minimum of 7 mm remaining bone height from the crest of the alveolar ridge to the inferior alveolar canal.
- Patients with adequate remaining interarch space
Key exclusion criteria (5 listed)
- Prior local radiation therapy.
- Soft and hard tissue pathology at the operation site.
- Systemic diseases that might affect bone healing and osseointegration (e.g., uncontrolled diabetes)..
- smokers who consume 20 or more cigarettes per day.
- patients on anti-resorptive drugs (eg: bisphosphonates and denosumab).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Allogenic Bone Ring Graft With Simultaneous Implant PlacementA surgical procedure involving vertical ridge augmentation using an allogenic bone ring combined with simultaneous dental implant placement in the posterior mandible. The technique allows one-stage treatment of vertical bone defects without the need for autogenous bone harvesting. | Procedure or surgery | Allogenic Bone Ring With Simultaneous Implant Placemen |
Primary outcome
Vertical Bone Gain in mm
Time frame: 6 months postoperatively
The vertical bone gain was measured radiographically using CBCT imaging to evaluate the effectiveness of the allogenic bone ring graft in augmenting vertical bone height in the posterior mandible
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jul 2025.
- Derived from this study: PubMed 41320709Hussein IT, Beder RR, Saad KA, Breshah MN. Evaluation of allogenic bone ring graft with simultaneous implant placement for vertical ridge augmentation. Oral Maxillofac Surg. 2025 Dec 1;30(1):4. doi: 10.1007/s10006-025-01487-4.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ibrahim T Hussein principal investigator
Faculty of Dentistry, Tanta University, Egypt
Rafic R Beder principal investigator
Faculty of Dentistry, Tanta University, Egypt
Khaled A Saad principal investigator
Faculty of Dentistry, Tanta University, Egypt
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Allogenic Bone Ring Graft With Simultaneous Implant Placement in people with Posterior Mandible With Deficient Ridge Height, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Vertical Bone Gain in mm (time frame: 6 months postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07054658, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jul 2025.