Depressive DisorderNCT07061600
Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media
A study testing "ich bin alles" and Instagram profile that provides educational content in people with Depressive Disorder and Depression - Major Depressive Disorder, run by Ludwig-Maximilians - University of Munich at 1 site in Germany.
Trial summary
Depression is a highly common mental disorder that often begins in adolescence. Despite its high burden and negative consequences, few young people seek professional help due to, e.g., low mental health literacy and fear of stigma. Read more about this study
- Who is it for?
- Ages 13 to 18 yearsHealthy volunteers can take part
- Conditions the study is for
- Depressive Disorder, Depression - Major Depressive Disorder, Depression in Adolescence
- What is being tested?
- "ich bin alles" and Instagram profile that provides educational content
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 170 participants
- Where
- 1 siteGermany
- Study dates
- 1 Apr 2025to 22 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 18 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Ownership of an Instagram account
- Regular use of Instagram
Who cannot join
- No exclusion citeria
Trial locations and contacts
1 site in 1 country.
Germany1 site
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich
Munich, Bavaria, 80336
About this study
Official title: Mental Health Literacy in the Digital Age: Assessing the Efficacy and Acceptance of a Social Media Intervention for Adolescent Depression With a Randomized Controlled Trial
Depression is a highly common mental disorder that often begins in adolescence. Despite its high burden and negative consequences, few young people seek professional help due to, e.g., low mental health literacy and fear of stigma. Since adolescents frequently seek health information online and use social media daily, the project "ich bin alles" (English: "I am everything"; www.ich-bin-alles.de) was launched to provide easily accessible, age-appropriate, and evidence-based information about depression and mental health via digital platforms including a website and social media channels (e.g., Instagram). This study aims to evaluate the effectiveness of the "ich bin alles"- Instagram channel in improving depression literacy, reducing stigma, and encouraging help-seeking behavior, as well as assessing user acceptance and content reception.
Read the detailed description
Depression is one of the most common mental disorders worldwide, with a prevalence of up to 7.5% in children and adolescents. In connection with the COVID-19 pandemic, a meta-analysis found an increase in clinically relevant depressive symptoms to 25.2% in children and adolescents. At the same time, adolescents who experience mental health crises are reluctant to seek help and only 12% of adolescents with clinically relevant depressive symptoms seek professional treatment. The main barriers for young people to seek professional help include low knowledge of mental disorders/low mental health literacy and social factors such as the fear of stigmatization. Mental health literacy (MHL) is defined as "how to prevent mental disorders, recognition of when a disorder is developing, knowledge of help-seeking options and treatment available, knowledge of effective self-help strategies for milder problems, and first aid skills to support others who are affected by mental health problems". It has been found that increased depression literacy can reduce depressive symptoms in adults and improve help-seeking for depression.
Stigma in the context of mental health is a multidimensional concept that encompasses several domains. For many people living with mental illness, stigma is a significant contributor to a wide range of negative outcomes, including delayed help-seeking, hopelessness, diminished self-esteem, reduced quality of life and poorer clinical outcomes. Many of these negative effects have also been found in young people with mental health problems. Therefore, improving MHL and reducing the stigmatization of mental illness are two important starting points that can serve as targets for interventions. Improved MHL goes hand in hand with better knowledge about seeking help and less stigmatization of mental illness.
The vast majority of adolescents in western countries, such as the US and Germany, have access to digital devices, such as smartphones, 97% of young people in the U.S. (13-17 years) state that they use social media and 45% say that they are online almost all the time. Along with this, young people are more likely to ask health questions, including mental health questions, online than through other channels. However, to date, few digital psychoeducational interventions for depression in adolescents have been developed and evaluated. In order to meet this need for action in a contemporary manner that attracts youth, the web-based project "ich bin alles" (English: "I am everything"; www.ich-bin-alles.de) was launched in September 2021 with an associated social media presence. The "ich bin alles" project provides comprehensive evidence-based and age-appropriate information on depression and mental health in youth via social media (such as Instagram).
The aim of this study is to investigate in a randomized controlled trial whether educating adolescents via Instagram is an effective and accepted method to inform about depression and mental health. In more detail, the effects of targeted communication of content via Instagram on (1) information regarding the appearance, causes, and development of depression, (2) stigma towards depression, and (3) help-seeking behaviour are investigated. It is examined whether this communication of information leads to an increase in depression literacy, a reduction in stigma, and an increase in the intention to seek help and whether these changes are maintained over three months. Furthermore, the acceptance of the content will be investigated.
In this study, participants will be randomly assigned to either an experimental group (EG) or an active control group (CG). Participants assigned to the EG will be asked to regularly consume "ich bin alles" Instagram content over the period of four weeks. The CG will be asked to regularly view content from an Instagram channel from the field of education created by a public broadcaster (https://www.instagram.com/terrax/) over the same time period. Before the reception of the content (pre), after four weeks (post), and at a three months follow-up, participants will fill out questionnaires via an app ("m-Path"), with each assessment lasting approx. 30 minutes. At each assessment point, participants simultaneously receive a push notification via the app to complete the questionnaire. The pre-assessment is intended to check the eligibility criteria and record demographic data such as gender, highest educational qualification, and current employment/education status. The primary outcome measures (depression literacy, intention to seek help, stigma) are assessed at pre, post, and follow-up. After 4 weeks, the post assessment will take place, during which acceptance is also tested in addition to the primary outcome measures. After another 3 months, the follow-up assessment is scheduled. During the four-week intervention period, Ecological Momentary Assessment will be used to ask adolescents a few short questions every day about their mood and their use of the Instagram channel via the m-Path app.
- Being tested
- "ich bin alles", Instagram profile that provides educational content
- Keywords
- depression, social media, adolescents, depression literacy, stigma, help-seeking, psychoeducation, ecological momentary assessment
- Medical subject headings
- Depressive Disorder, Depression, Social Stigma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
"ich bin alles"Behavioural
The web-based information platform "ich bin alles" (www-ich-bin-alles.de) on depression and mental health in youth as well as its Social Media channels were developed by the Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy of the LMU Munich Hospital together with the Prof. Otto Beisheim Foundation. It is aimed at youth with depression, healthy youth, and their parents. The project focuses on education, prevention, low-threshold support, and destigmatisation through the transfer of evidence-based knowledge and hands-on supportive materials. Information material on Instagram is posted four times a week in the form of a post, a longer explanatory video and two reels (i.e. short videos with overlays of text and music). All content is evidence-based information created by the research team and is primarily based on the "ich bin alles" page.
Instagram profile that provides educational contentBehavioural
Also called terrax
The participants of the control group asked to follow an Instagram profile that provides educational content produced by a public broadcaster (https://www.instagram.com/terrax/) and is not dedicated to the topic of mental health. This channel also posts several times a week and provides educational or informational content.
| Study group | Role | What they receive |
|---|---|---|
| "ich bin alles" (Instagram profile) | Experimental | The experimental group is encouraged to follow the "ich bin alles" Instagram account closely and to view the posted information material regularly over the period of 4 weeks. Receives: Behavioral: "ich bin alles" |
| Control Group | Active comparator | The active control group is asked to follow an Instagram profile that provides educational content produced by a public broadcaster. The educational content is not related to mental health issues (https://www.instagram.com/terrax/?hl=de). Receives: Behavioral: Instagram profile that provides educational content |
What is being measured
The primary outcome is the main question the study is designed to answer.
Depression Literacy
Assessed with an adapted version of the German version of the Adolescent Depression Knowledge Questionnaire and the Depression Literacy Scale German
Measured: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Stigma
Stigma - Assessed with the German version of the Self Stigma of Depression Scale and adapted Version of the Peer mental health stigmatization scale
Measured: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Intention to seek help
Assessed using the German version of the Attitudes Toward Seeking Professional Psychological Help Scale - Short Form
Measured: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Mental Health
Assessed with the Depression Screener for Teenagers and the Perceived Stress Scale
Measured: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Visual Aesthetics
Assessed via an adapted version of the Visual Aesthetics of Website Inventory - Short
Measured: post-test (week 4)
Intentions to act
Assessed via an adapted version of the Scale assessing the intention to revisit the website
Measured: post-test (week 4)
Overall impression
assessed via a single item based on Thielsch
Measured: post-test (week 4)
Secondary outcomes (1)
Ecological Momentary Assessment (Control function and mood changes)
Changes in mood and consumption of Instagram profiles over the period of the intervention through daily surveys using specially created items
Measured: every day between Pre-test (week 0) and post-test (week 4)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jul 2025
- Study start1 Apr 2025
- Primary completion22 Oct 2025
- Study completion22 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Depressive DisorderStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- After the recruitment phase, the participants are randomly assigned to either the experimental group (EG), which receives "ich bin alles" Instagram content, or the control group (CG) before the start of the study. The control group receives content from an Instagram profile in the field of education that is not related to mental health issues (https://www.instagram.com/terrax/?hl=de). Randomisation is carried out using 1:1 randomisation, stratified by age (\< 16 years vs. ≥ 16 years) and gender. With the exception of one team member, who will be responsible for the administration and randomisation of participants and will not be involved in the statistical analyses, participants and staff will be blind to allocation.
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 170 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ludwig-Maximilians - University of Munich
- Sponsor type
- University, hospital or other
- Collaborators
- Prof. Otto Beisheim Foundation
- Responsible party
- Principal investigator, Ellen Greimel, LMU Klinikum
- Investigators
- Gerd Schulte-Körne, Prof. Dr., Principal investigator, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07061600
- Sponsor's protocol ID
- 25-0085
- Status last verified
- Nov 2025
- First submitted
- 26 Jun 2025
- Last updated
- 4 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The data collected in this study include sensitive details about participants, such as various sociodemographic characteristics. Publicly sharing the raw dataset could risk revealing individual identities, thereby violating ethical standards related to participant confidentiality. As a result, the raw data will not be publicly released. However, detailed descriptions of the methodology, materials used, and sample characteristics will be provided within the article and supplementary materials. The intervention is also publicly accessible in German on the "ich bin alles" - Instagram channel. Aggregated data and additional supporting materials may be shared upon request (contact: sara.kaubisch@med.uni-muenchen.de).
Study at a glance
From the registry record, last updated by the sponsor on 4 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mental Health Literacy in the Digital Age: Assessing the Efficacy and Acceptance of a Social Media Intervention for Adolescent Depression With a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07061600
- Acronym / sponsor ID
- 25-0085
- Keywords
- depression, social media, adolescents, depression literacy, stigma, help-seeking, psychoeducation, ecological momentary assessment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 170 participants (actual)
- Lead sponsor
- Ludwig-Maximilians - University of MunichUniversity, hospital or other
- Collaborators
- Prof. Otto Beisheim Foundation
- Study start
- 1 Apr 2025 (actual)
- Primary completion
- 22 Oct 2025 (actual)
- Study completion
- 22 Oct 2025 (actual)
- First posted
- 11 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Depression is a highly common mental disorder that often begins in adolescence. Despite its high burden and negative consequences, few young people seek professional help due to, e.g., low mental health literacy and fear of stigma. Since adolescents frequently seek health information online and use social media daily, the project "ich bin alles" (English: "I am everything"; www.ich-bin-alles.de) was launched to provide easily accessible, age-appropriate, and evidence-based information about depression and mental health via digital platforms including a website and social media channels (e.g., Instagram). This study aims to evaluate the effectiveness of the "ich bin alles"- Instagram channel in improving depression literacy, reducing stigma, and encouraging help-seeking behavior, as well as assessing user acceptance and content reception.
Detailed description
Depression is one of the most common mental disorders worldwide, with a prevalence of up to 7.5% in children and adolescents. In connection with the COVID-19 pandemic, a meta-analysis found an increase in clinically relevant depressive symptoms to 25.2% in children and adolescents. At the same time, adolescents who experience mental health crises are reluctant to seek help and only 12% of adolescents with clinically relevant depressive symptoms seek professional treatment. The main barriers for young people to seek professional help include low knowledge of mental disorders/low mental health literacy and social factors such as the fear of stigmatization. Mental health literacy (MHL) is defined as "how to prevent mental disorders, recognition of when a disorder is developing, knowledge of help-seeking options and treatment available, knowledge of effective self-help strategies for milder problems, and first aid skills to support others who are affected by mental health problems". It has been found that increased depression literacy can reduce depressive symptoms in adults and improve help-seeking for depression.
Stigma in the context of mental health is a multidimensional concept that encompasses several domains. For many people living with mental illness, stigma is a significant contributor to a wide range of negative outcomes, including delayed help-seeking, hopelessness, diminished self-esteem, reduced quality of life and poorer clinical outcomes. Many of these negative effects have also been found in young people with mental health problems. Therefore, improving MHL and reducing the stigmatization of mental illness are two important starting points that can serve as targets for interventions. Improved MHL goes hand in hand with better knowledge about seeking help and less stigmatization of mental illness.
The vast majority of adolescents in western countries, such as the US and Germany, have access to digital devices, such as smartphones, 97% of young people in the U.S. (13-17 years) state that they use social media and 45% say that they are online almost all the time. Along with this, young people are more likely to ask health questions, including mental health questions, online than through other channels. However, to date, few digital psychoeducational interventions for depression in adolescents have been developed and evaluated. In order to meet this need for action in a contemporary manner that attracts youth, the web-based project "ich bin alles" (English: "I am everything"; www.ich-bin-alles.de) was launched in September 2021 with an associated social media presence. The "ich bin alles" project provides comprehensive evidence-based and age-appropriate information on depression and mental health in youth via social media (such as Instagram).
The aim of this study is to investigate in a randomized controlled trial whether educating adolescents via Instagram is an effective and accepted method to inform about depression and mental health. In more detail, the effects of targeted communication of content via Instagram on (1) information regarding the appearance, causes, and development of depression, (2) stigma towards depression, and (3) help-seeking behaviour are investigated. It is examined whether this communication of information leads to an increase in depression literacy, a reduction in stigma, and an increase in the intention to seek help and whether these changes are maintained over three months. Furthermore, the acceptance of the content will be investigated.
In this study, participants will be randomly assigned to either an experimental group (EG) or an active control group (CG). Participants assigned to the EG will be asked to regularly consume "ich bin alles" Instagram content over the period of four weeks. The CG will be asked to regularly view content from an Instagram channel from the field of education created by a public broadcaster (https://www.instagram.com/terrax/) over the same time period. Before the reception of the content (pre), after four weeks (post), and at a three months follow-up, participants will fill out questionnaires via an app ("m-Path"), with each assessment lasting approx. 30 minutes. At each assessment point, participants simultaneously receive a push notification via the app to complete the questionnaire. The pre-assessment is intended to check the eligibility criteria and record demographic data such as gender, highest educational qualification, and current employment/education status. The primary outcome measures (depression literacy, intention to seek help, stigma) are assessed at pre, post, and follow-up. After 4 weeks, the post assessment will take place, during which acceptance is also tested in addition to the primary outcome measures. After another 3 months, the follow-up assessment is scheduled. During the four-week intervention period, Ecological Momentary Assessment will be used to ask adolescents a few short questions every day about their mood and their use of the Instagram channel via the m-Path app.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- After the recruitment phase, the participants are randomly assigned to either the experimental group (EG), which receives "ich bin alles" Instagram content, or the control group (CG) before the start of the study. The control group receives content from an Instagram profile in the field of education that is not related to mental health issues (https://www.instagram.com/terrax/?hl=de). Randomisation is carried out using 1:1 randomisation, stratified by age (< 16 years vs. ≥ 16 years) and gender. With the exception of one team member, who will be responsible for the administration and randomisation of participants and will not be involved in the statistical analyses, participants and staff will be blind to allocation.
| Arm | Type | Receives |
|---|---|---|
| "ich bin alles" (Instagram profile) | Experimental | Behavioral: "ich bin alles"The experimental group is encouraged to follow the "ich bin alles" Instagram account closely and to view the posted information material regularly over the period of 4 weeks. |
| Control Group | Active comparator | Behavioral: Instagram profile that provides educational contentThe active control group is asked to follow an Instagram profile that provides educational content produced by a public broadcaster. The educational content is not related to mental health issues (https://www.instagram.com/terrax/?hl=de). |
Who may qualify
- Ages
- 13 to 18 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (2 listed)
- Ownership of an Instagram account
- Regular use of Instagram
Key exclusion criteria (1 listed)
- No exclusion citeria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| "ich bin alles"The web-based information platform "ich bin alles" (www-ich-bin-alles.de) on depression and mental health in youth as well as its Social Media channels were developed by the Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy of the LMU Munich Hospital together with the Prof. Otto Beisheim Foundation. It is aimed at youth with depression, healthy youth, and their parents. The project focuses on education, prevention, low-threshold support, and destigmatisation through the transfer of evidence-based knowledge and hands-on supportive materials. Information material on Instagram is posted four times a week in the form of a post, a longer explanatory video and two reels (i.e. short videos with overlays of text and music). All content is evidence-based information created by the research team and is primarily based on the "ich bin alles" page. | Behavioural | "ich bin alles" (Instagram profile) |
| Instagram profile that provides educational contentAlso: terraxThe participants of the control group asked to follow an Instagram profile that provides educational content produced by a public broadcaster (https://www.instagram.com/terrax/) and is not dedicated to the topic of mental health. This channel also posts several times a week and provides educational or informational content. | Behavioural | Control Group |
Primary outcome
Depression Literacy
Time frame: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Assessed with an adapted version of the German version of the Adolescent Depression Knowledge Questionnaire and the Depression Literacy Scale German
Stigma
Time frame: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Stigma - Assessed with the German version of the Self Stigma of Depression Scale and adapted Version of the Peer mental health stigmatization scale
Intention to seek help
Time frame: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Assessed using the German version of the Attitudes Toward Seeking Professional Psychological Help Scale - Short Form
Mental Health
Time frame: Pre-test (week 0), post-test (week 4), follow-up (week 16)
Assessed with the Depression Screener for Teenagers and the Perceived Stress Scale
Visual Aesthetics
Time frame: post-test (week 4)
Assessed via an adapted version of the Visual Aesthetics of Website Inventory - Short
Intentions to act
Time frame: post-test (week 4)
Assessed via an adapted version of the Scale assessing the intention to revisit the website
Overall impression
Time frame: post-test (week 4)
assessed via a single item based on Thielsch
1 secondary outcome
Ecological Momentary Assessment (Control function and mood changes)
Time frame: every day between Pre-test (week 0) and post-test (week 4)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Dec 2025.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: No. The data collected in this study include sensitive details about participants, such as various sociodemographic characteristics. Publicly sharing the raw dataset could risk revealing individual identities, thereby violating ethical standards related to participant confidentiality. As a result, the raw data will not be publicly released. However, detailed descriptions of the methodology, materials used, and sample characteristics will be provided within the article and supplementary materials. The intervention is also publicly accessible in German on the "ich bin alles" - Instagram channel. Aggregated data and additional supporting materials may be shared upon request (contact: sara.kaubisch@med.uni-muenchen.de).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gerd Schulte-Körne, Prof. Dr. principal investigator
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hospital of the Ludwig-Maximilians-University (LMU) Munich
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing "ich bin alles" and Instagram profile that provides educational content in people with Depressive Disorder and Depression - Major Depressive Disorder, run by Ludwig-Maximilians - University of Munich at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Depression Literacy (time frame: Pre-test (week 0), post-test (week 4), follow-up (week 16)). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2025.