AzTrials
AzTrials

Patellofemoral Pain SyndromeNCT07064044

Muscle Energy Technique With and Without Patellar Inferior Glide in Patients With Patellofemoral Pain Syndrome

A study testing Conventional Traetment and Muscle Energy Technique and Patellar Inferior Glide in people with Patellofemoral Pain Syndrome, run by Riphah International University at 1 site in Pakistan.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
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Trial summary

Patellofemoral pain syndrome (PFPS) is one of the most commonly diagnosed conditions among adolescents and adults with knee complaints, accounting for approximately 25% of knee disorders diagnosed in sports medical clinics. Read more about this study

Who is it for?
Ages 20 to 40 years
Conditions the study is for
Patellofemoral Pain Syndrome
What is being tested?
Conventional Traetment and Muscle Energy Technique and Patellar Inferior Glide
Could I receive a placebo?
No, everyone receives an active treatment
How many people
36 participants
Where
1 sitePakistan
Study dates
Jul 2025to Oct 2025
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 40 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Individuals with age 20-40Years
  • Pain rating > 3 and < 7 on NPRS
  • Patella alta confirmed with ISI (Insall Salvati index) ratio > 1.2 on lateral knee radiograph
  • Positive Ely's test for rectus femoris tightness
  • Positive eccentric step test

Who cannot join

  • History of patellofemoral dislocation
  • Knee osteoarthritis
  • Recently undergo to surgery to knee
  • Fracture in knee region
  • Positive patellar tap test for knee joint effusion
  • Lateral and medial tracking of patella
  • Patients taking NSAIDs and corticosteroids

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Samrood Akram, PhD Scholar contact

03324806143

samrood.akram@riphah.edu.pk.com

Pakistan1 site

  • Rims Rehabilitation Centre

    Multan Khurd, Punjab Province, 54000

    Narmeen Haseeb, MSPT, 923012721919, narmeen.haseeb.pt@gmail.com

Other trials in Pakistan

About this study

Official title: Effects of Muscle Energy Technique With and Without Patellar Inferior Glide on Pain, Range of Motion and Disability in Patients With Patellofemoral Pain Syndrome

Patellofemoral pain syndrome (PFPS) is one of the most commonly diagnosed conditions among adolescents and adults with knee complaints, accounting for approximately 25% of knee disorders diagnosed in sports medical clinics. While the etiology of PFPS is suggested to be multifactorial, several contributing factors such as lower knee extensors strength, quadriceps imbalance, weak hip abductors and overuse have been identified.

Read the detailed description

This study will be a randomized clinical trial and will be conducted in RIMS Rehabilitation Center Multan and Hadi Physiotherapy Center Multan. Non-probability convenient sampling will be used to collect the data. Sample size of 36 subjects with age group 20-40 years will be taken. Data will be collected from the patients having patellofemoral pain syndrome. Outcome measures will be taken using Numeric pain rating scale (NPRS) for pain, Universal Goniometer (GU) for Range of motion and Kujala Anterior Knee Pain Scale (AKPS) for disability. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups by random number generator table. Group A will receive muscle energy technique and patellar inferior glide and conventional physical therapy while group B will receive muscle energy technique and conventional treatment. Outcome measures will be measured at baseline and after 4 weeks. Data analysis will be done by SPSS version 25.

Being tested
Conventional Traetment, Muscle Energy Technique and Patellar Inferior Glide
Keywords
Pain, Disability, Range of motion
Medical subject headings
Patellofemoral Pain Syndrome, Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Conventional TraetmentOther

    TENS applied for 10 minutes, Therapeutic ultrasound,Hip abductors and lateral rotators strengthening, Hamstring muscle passive stretching, Isometrics for quadriceps, given thrice a week for 4 weeks .

  • Muscle Energy Technique and Patellar Inferior GlideOther

    Muscle Energy Technique for Hamstrings and Quadriceps While the patient contract muscle (Hamstring / Quadriceps) the therapist applies a gentle controlled force. After the contraction patient release and the therapist reposition the leg into a new barrier. Intensity of contraction will be 20-25-% of maximum strength. Each contraction will be held for 5-7 seconds, followed by additional passive stretching maintained for 30 and the relaxation patellar inferior glide applied at patella: the examiner applied a gentle downward force on the patella with their right hand, while the left hand controlled the direction of the patella's movement. This will be applied for 3-4 minutes as tolerated by the patient.

Study groups in NCT07064044
Study groupRoleWhat they receive
Muscle Energy Technique and Patellar Inferior GlideExperimentalMuscle Energy Technique for Hamstrings and Quadriceps While the patient contract muscle (Hamstring / Quadriceps) the therapist applies a gentle controlled force. After the contraction patient release and the therapist reposition the leg into a new barrier. Intensity of contraction will be 20-25-% of maximum strength. Each contraction will be held for 5-7 seconds, followed by additional passive stretching maintained for 30 and the relaxation patellar inferior glide applied at patella: the examiner applied a gentle downward force on the patella with their right hand, while the left hand controlled the direction of the patella's movement. This will be applied for 3-4 minutes as tolerated by the patient.
Receives: Other: Muscle Energy Technique and Patellar Inferior Glide
Conventional Physiotherapy treatmentActive comparatorTENS applied, Ultrasound therapeutic modality applied, Hip and knee muscles strengthening exercises
Receives: Other: Conventional Traetment

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Numerical Pain Rating Scale (NPRS)

    The Numeric Pain Rating Scale (NPRS) is perhaps the most frequently applied scale used to quantify pain intensity in the clinical setting. It is an 11-point numeric scale, ranging from 0 indicating no pain to 10 indicating worst pain imaginable

    Measured: upto 4 weeks

  2. Universal Goniometer

    Universal goniometer (UG) is commonly used as a standard method to evaluate range of motion (ROM) as part of joint motions.

    Measured: upto 4 weeks

  3. Kujala Anterior Knee Pain Scale (AKPS)

    The Kujala patellofemoral scoring system is a tool used to assess the functional ability of the knee joint, specifically in relation to patellofemoral-related issues. This scoring system ranges from 0 to 100, with higher scores indicating better knee function and less pain, while lower scores indicate greater dysfunction and more severe pain.

    Measured: upto 4 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted14 Jul 2025
  2. Study startJul 2025 (estimated)
  3. Primary completionOct 2025 (estimated)
  4. Study completionOct 2025 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
36 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07064044
Sponsor's protocol ID
REC/RCR &AHS/24/0162 Tayba
Status last verified
Jul 2025
First submitted
3 Jul 2025
Last updated
14 Jul 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Widhiantari NKE, Widnyana M, Jawi IM. Risk factors of the patellofemoral pain syndrome. Kinesiology and Physiotherapy Comprehensive. 2023;2(3):74-80.

  • Leon-Morillas F, Garcia-Marin M, Corujo-Hernandez C, Martin Aleman M, Castellote-Caballero Y, Cahalin LP, Infante-Guedes A, Cruz-Diaz D. Evaluating the Impact of Flossing Band Integration in Conventional Physiotherapy for Patellofemoral Pain Syndrome. J Clin Med. 2024 May 17;13(10):2958. doi: 10.3390/jcm13102958.

    PubMed 38792499

  • Abd Elhady AM, Abd Elmajeed SF, Abd Allah WA, Abd Elhamed HB. Knee Alignment-Oriented Balance Exercises Versus Conventional Balance Exercises in Treating Patellofemoral Pain Syndrome. The Egyptian Journal of Hospital Medicine (January 2024).94:975-81.

  • Raju A, Jayaraman K, Nuhmani S, Sebastian S, Khan M, Alghadir AH. Effects of hip abductor with external rotator strengthening versus proprioceptive training on pain and functions in patients with patellofemoral pain syndrome: A randomized controlled trial. Medicine (Baltimore). 2024 Feb 16;103(7):e37102. doi: 10.1097/MD.0000000000037102.

    PubMed 38363950

  • Mv VK, Subramanian NB, S S, Kotamraju S, Krishnan M. Physiotherapeutic interventions on quadriceps muscle architecture in patello-femoral pain syndrome. Bioinformation. 2023 Apr 30;19(4):454-459. doi: 10.6026/97320630019454. eCollection 2023.

    PubMed 37822824

  • Veeresh G, Kumar SS, Sasidharan S. MANUAL THERAPY FOR PATELLOFEMORAL PAIN SYNDROME REVIEW OF LITERATURE. EPRA International Journal of Multidisciplinary Research (IJMR). 2024;10(5):298-309.

Questions about this trial

What is this clinical trial studying?

A study testing Conventional Traetment and Muscle Energy Technique and Patellar Inferior Glide in people with Patellofemoral Pain Syndrome, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 14 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Samrood Akram, PhD Scholar (03324806143, samrood.akram@riphah.edu.pk.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Numerical Pain Rating Scale (NPRS) (time frame: upto 4 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07064044, which also lists 6 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jul 2025.

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