Bariatric or General Abdominal SurgeriesNCT07064200
TAP Block Timing Study
A study testing TAP Block in people with Bariatric or General Abdominal Surgeries and Bariatric Surgery Patients, run by Weill Medical College of Cornell University at 1 site in United States.
Trial summary
This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients undergoing elective abdominal surgeries. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Bariatric or General Abdominal Surgeries, Bariatric Surgery Patients
- What is being tested?
- TAP Block
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteUnited States
- Study dates
- 14 Jul 2025to Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged between 18 and 65 years
- Scheduled for elective bariatric surgery or other elective general abdominal surgeries
- Proficient in English sufficient to understand study procedures and communicate effectively
- Capable of providing informed consent
Who cannot join
- Individuals under 18 years of age (minors)
- Pregnant individuals
- Prisoners
- Individuals with cognitive impairments or otherwise unable to provide informed consent independently
- Individuals with known allergies or contraindications to local anesthetics used in TAP blocks
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Hasan Ali contact
United States1 site, 1 recruiting
- Recruiting
Weill Cornell Medical College - NewYork-Presbyterian Hospital
New York, New York, 10065
Hasan Ali, (646) 962-8462, hoa4002@qatar-med.cornell.edu
Cheguevara Afaneh, MD
About this study
Official title: Transversus Abdominis Plane (TAP) Blocks in Bariatric and General Surgery: Does Timing Matter?
This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients undergoing elective abdominal surgeries.
- Being tested
- TAP Block
- Keywords
- bariatric analgesia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
TAP BlockOther
the TAP block is a regional anesthesia technique that targets the somatic nerves supplying the anterior abdominal wall.
| Study group | Role | What they receive |
|---|---|---|
| Pre-Incision | Other | TAP block administration pre-incision Receives: Other: TAP Block |
| Post-Incision | Other | TAP block administration post-incision Receives: Other: TAP Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean change in opioid consumption (MME) from index procedure to 90 days post-op
Opioid dosage quantities will be measured in morphine milligram equivalents (MME)
Measured: Up to 90 days post-operatively
Change in Pain Scores from index procedure on a numerical rating scale
Patient-reported pain on a scale of 1-10.
Measured: 1, 3, 6, 24, 48, and 72 hours postoperatively
Secondary outcomes (4)
1. Total Opioid Consumption in MME from Surgery to 90 Days Postoperatively
Sum of all opioid use from surgery to 90 days, in MME
Measured: From end of surgery to 90 days post-op.
Patient Satisfaction Score with Postoperative Pain Management at Discharge
Satisfaction score using a 5-point Likert scale survey before discharge.
Measured: At hospital discharge (within 3-5 days post-op)
Use of Non-Opioid Analgesics within 72 Hours
Count of participants receiving non-opioid pain medications (e.g. acetaminophen, NSAIDs) within 72 hours post-op, including amount and type.
Measured: From end of surgery to 72 hours post-op
Number of Participants with TAP Block-Related Adverse Events
Incidence of adverse events (e.g. local anesthetic toxicity, infection, bleeding) related to TAP block.
Measured: From TAP block administration to 90 days post-op.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2025
- Study start14 Jul 2025
- Primary completion1 Dec 2026 (estimated)
- Study completionJul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bariatric or General Abdominal SurgeriesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Weill Medical College of Cornell University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Cheguevara Afaneh, MD, Principal investigator, Weill Medical College of Cornell University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07064200
- Sponsor's protocol ID
- 25-04028793
- Status last verified
- Jan 2026
- First submitted
- 2 Jul 2025
- Last updated
- 27 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices)
Study at a glance
From the registry record, last updated by the sponsor on 27 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Transversus Abdominis Plane (TAP) Blocks in Bariatric and General Surgery: Does Timing Matter?
- ClinicalTrials.gov ID
- NCT07064200
- Acronym / sponsor ID
- 25-04028793
- Keywords
- bariatric analgesia
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- Weill Medical College of Cornell UniversityUniversity, hospital or other
- Study start
- 14 Jul 2025 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- Jul 2027 (estimated)
- First posted
- 14 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients undergoing elective abdominal surgeries.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Pre-Incision | Other | Other: TAP BlockTAP block administration pre-incision |
| Post-Incision | Other | Other: TAP BlockTAP block administration post-incision |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adults aged between 18 and 65 years
- Scheduled for elective bariatric surgery or other elective general abdominal surgeries
- Proficient in English sufficient to understand study procedures and communicate effectively
- Capable of providing informed consent
Key exclusion criteria (5 listed)
- Individuals under 18 years of age (minors)
- Pregnant individuals
- Prisoners
- Individuals with cognitive impairments or otherwise unable to provide informed consent independently
- Individuals with known allergies or contraindications to local anesthetics used in TAP blocks
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| TAP Blockthe TAP block is a regional anesthesia technique that targets the somatic nerves supplying the anterior abdominal wall. | Other | Post-Incision, Pre-Incision |
Primary outcome
Mean change in opioid consumption (MME) from index procedure to 90 days post-op
Time frame: Up to 90 days post-operatively
Opioid dosage quantities will be measured in morphine milligram equivalents (MME)
Change in Pain Scores from index procedure on a numerical rating scale
Time frame: 1, 3, 6, 24, 48, and 72 hours postoperatively
Patient-reported pain on a scale of 1-10.
4 secondary outcomes
1. Total Opioid Consumption in MME from Surgery to 90 Days Postoperatively
Time frame: From end of surgery to 90 days post-op.
Patient Satisfaction Score with Postoperative Pain Management at Discharge
Time frame: At hospital discharge (within 3-5 days post-op)
Use of Non-Opioid Analgesics within 72 Hours
Time frame: From end of surgery to 72 hours post-op
Number of Participants with TAP Block-Related Adverse Events
Time frame: From TAP block administration to 90 days post-op.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Jan 2026.
- Individual participant dataSharing planned: Yes. Individual participant data that underlie the results reported in this article, after deidentification (text, tables, figures, and appendices)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Hasan Ali contact
Cheguevara Afaneh, MD principal investigator
Weill Medical College of Cornell University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing TAP Block in people with Bariatric or General Abdominal Surgeries and Bariatric Surgery Patients, run by Weill Medical College of Cornell University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 27 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Cheguevara Afaneh, MD (+1 646 962 8462, cha9043@med.cornell.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean change in opioid consumption (MME) from index procedure to 90 days post-op (time frame: Up to 90 days post-operatively). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Jan 2026.