Thoracic SurgeryNCT07065890
Association Between Body Roundness Index and Wound Healing
An observational study of Thoracic Surgery and Obesity, run by Zhao bo at 1 site in China.
Trial summary
Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery. Read more about this study
- Who is it for?
- Ages 20 to 80 years
- Conditions the study is for
- Thoracic Surgery, Obesity, BMI
- How many people
- 422 participants
- Where
- 1 siteChina
- Study dates
- 1 Oct 2024to 1 May 2025
- How long will I take part?
- 30 Days
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning.
Who may be able to join
- Patients who underwent surgical treatment in the Department of Thoracic Surgery at Tongji Hospital;
- Complete clinical data and diagnostic test results available;
- Postoperative follow-up conducted regularly in accordance with medical advice, with comprehensive follow-up records；
Who cannot join
- Without surgery or transferred to other departments；
- Missing basic information；
- Failure to review on time or refusal to follow up；
- Additional surgeries within 30 days of discharge from the hospital；
Trial locations and contacts
1 site in 1 country.
China1 site
Tongji Medical College of HUST Tongji Medical College Tongji Hospital
Wuhan, Hubei, 430000
About this study
Official title: Association Between Body Roundness Index and Wound Healing Post-Thoracic Surgery: A Prospective Study
Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery.
Methods This study included 387 patients who underwent thoracic surgery at Tongji Hospital in Wuhan between October 2024 and January 2025. Wound healing was assessed 30 days postoperatively. Logistic regression and propensity score matching (PSM) analyses were performed to evaluate the relationship between BRI and impaired wound healing, with subgroup analyses conducted to further explore this association.
Read the detailed description
This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning (Figure 1). The primary objective was to evaluate the association between BRI and impaired postoperative wound healing through multivariable logistic regression, propensity score matching (PSM), and subgroup analyses.
- Conditions
- Thoracic Surgery, Obesity, BMI, Visceral Fat, Wound Healing
- Keywords
- BRI, Thoracic Surgery, Wound Healing, BMI, Obesity
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| impaired wound healing | This cohort include individuals diagnosed with poor wound healing according to the definitions and guidelines for assessment of wounds and evaluation of healing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Wound healing
Determine the presence of impaired wound healing based on the definitions and guidelines for wound assessment and evaluation of healing.
Measured: From the day of surgery to 30 days postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jul 2025
- Study start1 Oct 2024
- Primary completion30 Jan 2025
- Study completion1 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thoracic SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 422 participants (actual)
- Target duration
- 30 Days
Sponsor and investigators
- Lead sponsor
- Zhao bo
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Zhao bo, Tongji Hospital
- Investigators
- Zhang q Zhang, Dr., Study director, Tongji Medical College of HUST Tongji Medical College Tongji Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07065890
- Sponsor's protocol ID
- TJ-JRB202503009
- Status last verified
- Jul 2025
- First submitted
- 2 Jul 2025
- Last updated
- 15 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Association Between Body Roundness Index and Wound Healing Post-Thoracic Surgery: A Prospective Study
- ClinicalTrials.gov ID
- NCT07065890
- Acronym / sponsor ID
- TJ-JRB202503009
- Conditions
- Thoracic Surgery, Obesity, BMI, Visceral Fat, Wound Healing
- Keywords
- BRI, Thoracic Surgery, Wound Healing, BMI, Obesity
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 422 participants (actual)
- Lead sponsor
- Zhao boUniversity, hospital or other
- Study start
- 1 Oct 2024 (actual)
- Primary completion
- 30 Jan 2025 (actual)
- Study completion
- 1 May 2025 (actual)
- First posted
- 15 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery.
Methods This study included 387 patients who underwent thoracic surgery at Tongji Hospital in Wuhan between October 2024 and January 2025. Wound healing was assessed 30 days postoperatively. Logistic regression and propensity score matching (PSM) analyses were performed to evaluate the relationship between BRI and impaired wound healing, with subgroup analyses conducted to further explore this association.
Detailed description
This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning (Figure 1). The primary objective was to evaluate the association between BRI and impaired postoperative wound healing through multivariable logistic regression, propensity score matching (PSM), and subgroup analyses.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 30 Days
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| impaired wound healing | – | –This cohort include individuals diagnosed with poor wound healing according to the definitions and guidelines for assessment of wounds and evaluation of healing |
Who may qualify
- Ages
- 20 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning.
Key inclusion criteria (3 listed)
- Patients who underwent surgical treatment in the Department of Thoracic Surgery at Tongji Hospital;
- Complete clinical data and diagnostic test results available;
- Postoperative follow-up conducted regularly in accordance with medical advice, with comprehensive follow-up records；
Key exclusion criteria (4 listed)
- Without surgery or transferred to other departments；
- Missing basic information；
- Failure to review on time or refusal to follow up；
- Additional surgeries within 30 days of discharge from the hospital；
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Wound healing
Time frame: From the day of surgery to 30 days postoperatively
Determine the presence of impaired wound healing based on the definitions and guidelines for wound assessment and evaluation of healing.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jul 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Zhang q Zhang, Dr. study director
Tongji Medical College of HUST Tongji Medical College Tongji Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Thoracic Surgery and Obesity, run by Zhao bo at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Wound healing (time frame: From the day of surgery to 30 days postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jul 2025.