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MSK ConditionsNCT07072702

Feasibility and Acceptability of an Evidence-Informed Virtual Intervention to Reduce Perceptions of Injustice Following Work Injury

A study testing Managing Post-Injury Challenges (MPIC) in people with MSK Conditions, run by McGill University at 1 site in Canada.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Many individuals who have sustained disabling injuries in the workplace react to their situation with a sense of 'injustice'. Research over the past 20 years has revealed that, interpreting one's post-injury life situation as 'unjust', actually interferes with recovery from the disabling injury. Read more about this study

Who is it for?
Ages 25 to 65 years
Conditions the study is for
MSK Conditions
What is being tested?
Managing Post-Injury Challenges (MPIC)
Could I receive a placebo?
No, everyone receives an active treatment
How many people
75 participants
Where
1 siteCanada
Study dates
30 Sep 2024to 30 Jun 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 25 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • working knowledge of English,
  • work absence of less than 8 weeks duration following a musculoskeletal injury to the back or neck,
  • a score above clinical threshold on a self-report measure of perceived injustice,
  • between 25 and 65 years of age,
  • referred for primary care physiotherapy, and
  • currently receiving wage indemnity benefits from the WSIB.

Who cannot join

  • currently receiving psychological services for a mental health problem,
  • clinical evidence of vertebral fracture, disk herniation, infectious disease, or rheumatoid arthritis (determined from referral information),
  • illiteracy or severe cognitive impairment (determined informally through the intake interview).

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Michael Sullivan Sullivan, PhD contact

1-514-512-7246

michael.sullivan@mcgill.ca

Canada1 site, 1 recruiting
  • McGill University

    Montreal, Quebec, H3A 1G1

    Michael J Sullivan, PhD, 514-512-7246, michael.sullivan@mcgill.ca

    Recruiting

Other trials in Canada

About this study

Many individuals who have sustained disabling injuries in the workplace react to their situation with a sense of 'injustice'. Research over the past 20 years has revealed that, interpreting one's post-injury life situation as 'unjust', actually interferes with recovery from the disabling injury. Post-injury perceptions of injustice contribute to more severe pain, more severe symptoms of depression and PTSD, and more prolonged absence from work. Several clinical researchers have highlighted the need to develop approaches to treatment that can reduce post-injury perceptions of injustice.

A brief intervention was developed to reduce post-injury perceptions of injustice. The intervention consists of 4 30-minute sessions with a psychologist. The intervention is called 'Managing Post-Injury Challenges' (MPIC). The MPIC sessions are delivered virtually (online). As a first step toward determining whether MPIC has added value for promoting more successful recovery following work injury, the proposed research will assess the feasibility of MPIC. Some of the feasibility questions that will be addressed include: Are injured workers interested in participating in MPIC? Do injured individuals remain sufficiently engaged to complete all 4 sessions of MPIC? Does participation in MPIC contribute to meaningful reductions in perceived injustice? And are injured individuals satisfied with the benefits of MPIC?

MPIC differs from many other rehabilitation interventions in that it focuses on a 'risk-factor' for problematic recovery as opposed to treating a specific health or mental health problem. At this time, there is little information about whether injured workers are interested in interventions focusing on 'risk factors' for problematic recovery. As a first step in evaluating the effectiveness of MPIC, it is necessary to demonstrate that MPIC is acceptable to injured workers. We would consider the study to be successful if 1) at least 75% of eligible injured workers agree to enrol in MPIC, 2) if at least 75% of participants attend all 4 sessions of MPIC, and if at least 75% of participants are satisfied with the benefits they derived from their involvement in MPIC. If MPIC is ultimately shown to be effective in reducing post-injury perceptions of injustice, offering MPIC to injured workers with elevated scores on a measure of perceived injustice could contribute to more successful recovery.

Read the detailed description

There is increasing evidence that perceptions of injustice can contribute to adverse recovery outcomes in individuals with disabling musculoskeletal conditions. Individuals who obtain elevated scores on measures of perceived injustice also report more severe pain, reduced participation in important activities of daily living, prolonged work disability, and the persistence of symptoms of mental health problems such as depression and post-traumatic stress disorder. Recent reviews of the literature have concluded that perceptions of injustice are strong predictors of disability and depression in individuals with musculoskeletal conditions. The emerging pattern of findings suggests that perceived injustice triggers a cascade of cognitive (i.e., rumination), emotional (anger, depression) and behavioural (i.e., activity withdrawal, medication overuse) reactions that can impede recovery. The relation between perceived injustice and adverse recovery outcomes has been demonstrated in individuals with work-related low back pain, whiplash injuries, catastrophic injuries, traumatic head injuries, fibromyalgia, sickle cell disease , osteoarthritis, and rheumatoid arthritis.

Although there are currently no intervention programs that have been developed specifically to modify perceptions of injustice following work injury, there are indications that treatment-related reductions in perceptions of injustice are prospectively associated with more positive rehabilitation outcomes. For example, one study reported that reductions in perceptions of injustice predicted occupational re-engagement in work-disabled individuals participating in a 10-week behavioural activation program. In the latter study, reductions in perceived injustice predicted return to work even when controlling for treatment-related reductions in pain severity. In a separate study, treatment-related reductions in perceptions of injustice were found to prospectively predict reductions in depressive symptom severity in work-disabled individuals with Major Depressive Disorder. The research that has accumulated to date suggests that an intervention specifically designed to reduce perceptions of injustice could contribute to more positive recovery outcomes in individuals who have sustained debilitating musculoskeletal injuries.

The purpose of the proposed study is to test the feasibility and impact of a 4-week psychosocial intervention, delivered remotely, designed to reduce perceptions of injustice following occupational injury. The intervention consists of 4 30-minute virtual meetings with a psychologist trained in the delivery of the intervention protocol. The intervention protocol has been termed, 'Managing Post-Injury Challenges' (MPIC). The intervention protocol is manualized and combines several evidence-supported treatment elements including validation, motivational interviewing, acceptance and problem-solving. The intervention protocol will be delivered concurrently with physiotherapy treatment.

Participants

The study sample will consist of 75 individuals who are absent from work due to a musculoskeletal injury. All participants will be receiving primary care physical therapy from one of 4 clinics. Eligibility criteria will include 1) receiving or having applied for time-loss benefits from the WSIB for a musculoskeletal injury to the back or neck, 2) date of injury less than 6 weeks prior to enrolment in the study, 3) a score above risk threshold on a self-report measure of perceived injustice, and 4) working knowledge of French or English. Individuals who are currently receiving psychological treatment will not be considered for participation.

Measures

All self-report measures will be administered through a secure web-based data capture system (RedCap).

Demographic and Injury-Related Variables. Participants will be asked to complete a general information form where they will be asked to respond to questions concerning their age, sex, education, marital status, number of children at home, occupation, previous time loss claims and current medication intake.

Perceived injustice: The Injustice Experiences Questionnaire (IEQ) will be used to measure injury-related perceptions of injustice.

Pain Severity: The McGill Pain Questionnaire Short-Form (MPQ-SF) will be used to measure pain severity.

Depressive symptoms: The Patient Health Questionnaire-9 (PHQ-9) will be used to assess depressive symptom severity. Self-Reported Disability: The WHODAS 2.0 will be used to assess self-rated disability.

Treatment satisfaction will be assessed at treatment termination. Return to Work. Return-to-work status will be assessed by telephone interview at treatment termination and 3-month follow-up.

Procedure

Consecutive referrals meeting the inclusion criteria for the study will be invited to participate. Prospective participants will be provided with a brief description of the intent of the MPIC intervention and will be asked for permission to be contacted by one of the MPIC clinicians. Prospective participants who agree to participate in the MPIC intervention will be provided with a link to a secure portal that will be used to administer all self-report measures used in the proposed research. MPIC sessions will be scheduled at a mutually convenient time for the MPIC clinician and the participants, and will be held weekly for 4 consecutive weeks. All self-report measures will be administered at the time of enrollment in the study (Week 1), at termination of the MPIC intervention (Week 4) and at 3-month follow-up. Treatment satisfaction will only be assessed at termination of the MPIC intervention.

A post-treatment debriefing interview will be conducted at 3-month follow-up. The aim of the post-treatment interview will be to examine participants' reflections on aspects of the intervention that they considered beneficial and aspects of the intervention that they did not consider beneficial. These interviews will provide important information to guide possible modifications to the intervention protocol that could increase its engagement value and impact.

The short-term expected outcome is that we will demonstrate that MPIC will yield clinically significant reductions in perceived injustice. We also expect that the results of the study will show that reductions in perceived injustice predict more positive recovery outcomes.

The next step in the evolution of this program of research would be to confirm the effectiveness of MPIC within the context of a randomized controlled trial. The long-term expected outcome is that there will be interest from the clinical practice community to acquire the skill set required to deliver the MPIC intervention.

The telehealth model of service delivery also has several advantages over face-to-face treatment including ease of incorporation into other health services to which participants might have been referred, physical accessibility, geographical reach, low cost, and feasibility of quality monitoring. The advantages of combining a risk-targeted intervention with an accessible service delivery model, while minimizing displacement challenges for individuals with a disabling health condition might provide the optimal approach for reducing the pain, disability and chronicity that can ensue in the aftermath of work injury.

It is anticipated that the study findings will reveal that the risk-targeted intervention yields meaning reductions in perceived injustice, and in turn, contributes to more positive recovery outcomes. Such findings would support the addition of the risk-targeted intervention to the repertoire of services made available to injured workers. The telehealth delivery model would maximize the scalable potential of the intervention to meet the needs of the target population. Training modules could be developed to disseminate the skill set required to deliver the intervention to the broader clinical practice community.

Conditions
MSK Conditions
Being tested
Managing Post-Injury Challenges (MPIC)
Keywords
Pain, Disability, Psychosocial, Perceived Injustice
Medical subject headings
Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Managing Post-Injury Challenges (MPIC)Behavioural

    A brief evidence-informed intervention was developed to reduce post-injury perceptions of injustice. The intervention is referred to as 'Mastering Post-Injury Challenges' (MPIC). MPIC consists of 4 weekly 30-minute virtual meetings with a psychologist trained in the delivery of the intervention. MPIC is delivered concurrently with the physiotherapy treatment to which the injured worker has been referred. MPIC combines elements of validation, motivational interviewing, acceptance and problem-solving .

Study groups in NCT07072702
Study groupRoleWhat they receive
MPICExperimentalA brief evidence-informed intervention was developed to reduce post-injury perceptions of injustice. The intervention is referred to as 'Managing Post-Injury Challenges' (MPIC). MPIC consists of 4 weekly 30-minute virtual meetings with a psychologist trained in the delivery of the intervention. MPIC is delivered concurrently with the physiotherapy treatment to which the injured worker has been referred. MPIC combines elements of validation, motivational interviewing, acceptance and problem-solving.
Receives: Behavioral: Managing Post-Injury Challenges (MPIC)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Perceived Injustice

    The Injustice Experiences Questionnaire (IEQ) will be used to assess post-injury perceptions of injutice.

    Measured: The IEQ will be administered pre-treatment, treatment termination and 3-month follow-up.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Jul 2025
  2. Study start30 Sep 2024
  3. Primary completion30 Mar 2026 (estimated)
  4. Study completion30 Jun 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Model description
This feasibility study will use a 4-centre (clinic), single arm, prospective design.
Masking
None (open label)
Enrolment
75 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07072702
Sponsor's protocol ID
SULL2024
Status last verified
Jul 2025
First submitted
8 May 2025
Last updated
18 Jul 2025
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided: Data will be shared upon reasonable request.

Questions about this trial

What is this clinical trial studying?

A study testing Managing Post-Injury Challenges (MPIC) in people with MSK Conditions, run by McGill University at 1 site in Canada.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 18 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Michael Sullivan Sullivan, PhD (1-514-512-7246, michael.sullivan@mcgill.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Perceived Injustice (time frame: The IEQ will be administered pre-treatment, treatment termination and 3-month follow-up.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jul 2025.

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