Obese Children and AdolescentsNCT07073651

Response of Lipid Profile to Virtual Reality Games Versus Moderate Aerobic Exercise Training in Children With Obesity

A study testing Moderate Intensity Aerobic Exercise, Dietary Advices and Virtual reality games exercise in people with Obese Children and Adolescents and Adolescent Obesity, run by Badr University at 2 sites in Egypt.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

Search all trials

Trial summary

This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity Read more about this study

Who is it for?: Ages 11 to 18 years
Conditions the study is for: Obese Children and Adolescents, Adolescent Obesity, Obesity
What is being tested?: Moderate Intensity Aerobic Exercise, Dietary Advices and Virtual reality games exercise
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 120 participants
Where: 2 sitesEgypt
Study dates: 10 Jul 2024to 30 Jun 2025
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 11 to 18 years
All sexes
No healthy volunteers
Child, Adult

Who may be able to join

Obese adolescent children
age from 11 to 18 years old only.
Class I Obesity (Body Mass Index from 30 to 34.99 kg/m2)
Clinically and medically stable
Without any impairment of sensation or other neurological or psychological problems.

Who cannot join

Adolescents with visual and/or auditory defects
Normal weight adolescent children (Body Mass Index from 18 to 24.99 kg/m2) or below average weight (BMI less than 18 kg/m2) or Class II and III Obesity (BMI above 35 kg/m2)
Children with significant tightness and/or deformity of upper or lower limbs
Participants with neurological disorders that affect balance or mentality (e.g. epilepsy).
Adolescents with advanced radiographic changes include: Bone destruction, Bony ankylosis, Knee joint subluxation, and Epiphysial fracture)
Any lower limb deformities in the lower limbs.
Participants with cardiopulmonary diseases.
Diabetic children or those under insulin therapy, uncontrolled bronchial asthma, anemia, and Pathological causes of obesity (endocrinal, genetic syndromes...etc.).

Trial locations and contacts

2 sites in 1 country.

Egypt2 sites

Badr University in Cairo faculty of physical therapy
Cairo
El-Mahaba Specialized Charity Polyclinics.
Cairo

Other trials in Egypt

About this study

This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity

Read the detailed description

The study will assess whether virtual reality games, dietary advices and moderate intensity aerobic exercise lead to significant differences in lipid profile in class I obese adolescent children. Additionally, the study will examine whether these interventions has impacts on the children body mass index.

Conditions: Obese Children and Adolescents, Adolescent Obesity, Obesity, Body Mass Index
Being tested: Moderate Intensity Aerobic Exercise, Dietary Advices, Virtual reality games exercise
Keywords: Obesity, Body mass index, Virtual Reality games, aerobic exercise, adolescent obesity, obese children, Moderate intensity aerobic exercise, dietary advices
Medical subject headings: Pediatric Obesity, Obesity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Moderate Intensity Aerobic ExerciseOther
moderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes.
Dietary AdvicesOther
The Obese adolescent children participated in the study received diet advices based on a balanced low calorie diet (1500 Kcal)
Virtual reality games exerciseOther
Virtual reality games exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercises to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises)

Study groups in NCT07073651
Study group	Role	What they receive
Virtual Reality Exercise	Experimental	The experimental group included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advices and virtual reality exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercise to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises) Receives: Other: Dietary Advices; Other: Virtual reality games exercise
Moderate intensity aerobic exercise	Active comparator	This group serves as the control group, it included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advice and moderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes. Receives: Other: Moderate Intensity Aerobic Exercise; Other: Dietary Advices

What is being measured

The primary outcome is the main question the study is designed to answer.

Body mass index
It is the weight (in kilograms) divided by the height (in meter squares)
Measured: From enrollment to the end of treatment at 12 weeks
Serum triglycerides
Level of triglycerides fats in blood in measured in laboratory using venous blood sample
Measured: From enrollment to the end of treatment at 12 weeks
Total Cholesterol
Level of total cholesterol in blood in measured in laboratory using venous blood sample
Measured: From enrollment to the end of treatment at 12 weeks
High Density Lipoproteins (HDL)
High Density Lipoproteins (HDL) cholesterol fats are measured in laboratory using a venous blood sample
Measured: From enrollment to the end of treatment at 12 weeks
Low Density Lipoproteins (LDL)
Low Density Lipoproteins (LDL) cholesterol fats are measured in laboratory using a venous blood sample
Measured: From enrollment to the end of treatment at 12 weeks

Secondary outcomes (1)

HDL ratio
The number of total cholesterol divided by high-density lipoprotein (HDL)
Measured: From enrollment to the end of treatment at 12 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

10 Jul 202430 Jun 2025

First posted18 Jul 2025
Study start10 Jul 2024
Primary completion31 May 2025
Study completion30 Jun 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Obese Children and AdolescentsStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 120 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07073651
Sponsor's protocol ID: IRB00014233-8
Status last verified: Jul 2025
First submitted: 10 Jul 2025
Last updated: 18 Jul 2025
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

Not yet recruiting
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
Binge Eating Disorder, Binge Eating
Not yet recruiting
Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)
Binge Eating, Overweight and Obesity
RecruitingPhase 3
A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults
Monogenic Obesity
Recruiting
SMART GOALS for Youth With Prediabetes
PreDiabetes, Adolescent Obesity
Active, not recruitingPhase 2
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic Obesity, Hypothalamic Tumor

All Obese Children and Adolescents trials

Study at a glance

From the registry record, last updated by the sponsor on 18 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Response of Lipid Profile to Virtual Reality Games Versus Moderate Aerobic Exercise Training in Children With Obesity
ClinicalTrials.gov ID: NCT07073651
Acronym / sponsor ID: IRB00014233-8
Conditions: Obese Children and Adolescents, Adolescent Obesity, Obesity, Body Mass Index
Keywords: Obesity, Body mass index, Virtual Reality games, aerobic exercise, adolescent obesity, obese children, Moderate intensity aerobic exercise, dietary advices
Study type: Interventional
Recruitment status: Completed
Enrolment: 120 participants (actual)
Lead sponsor: Badr UniversityUniversity, hospital or other
Study start: 10 Jul 2024 (actual)
Primary completion: 31 May 2025 (actual)
Study completion: 30 Jun 2025 (actual)
First posted: 18 Jul 2025 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity

Detailed description

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2

Arm	Type	Receives
Virtual Reality Exercise	Experimental	Other: Dietary Advices, Other: Virtual reality games exerciseThe experimental group included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advices and virtual reality exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercise to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises)
Moderate intensity aerobic exercise	Active comparator	Other: Moderate Intensity Aerobic Exercise, Other: Dietary AdvicesThis group serves as the control group, it included 60 adolescent obese children of both genders (class I obesity, BMI: 30-34.99) who received diet advice and moderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes.

Who may qualify

Ages: 11 to 18 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Child, Adult

Key inclusion criteria (5 listed)

Obese adolescent children
age from 11 to 18 years old only.
Class I Obesity (Body Mass Index from 30 to 34.99 kg/m2)
Clinically and medically stable
Without any impairment of sensation or other neurological or psychological problems.

Key exclusion criteria (8 listed)

Adolescents with visual and/or auditory defects
Normal weight adolescent children (Body Mass Index from 18 to 24.99 kg/m2) or below average weight (BMI less than 18 kg/m2) or Class II and III Obesity (BMI above 35 kg/m2)
Children with significant tightness and/or deformity of upper or lower limbs
Participants with neurological disorders that affect balance or mentality (e.g. epilepsy).
Adolescents with advanced radiographic changes include: Bone destruction, Bony ankylosis, Knee joint subluxation, and Epiphysial fracture)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Moderate Intensity Aerobic Exercisemoderate intensity aerobic exercises (using treadmill training) 5 times per week for 12 weeks. Each participating child started the session with 5 minutes of warming-up exercises. Then the main exercise phase is performed at 50-60% of age-predicted peak heart rate using a treadmill for 30 minutes. Finally, a 5 min cool-down period is allowed, the total session took 40 minutes.	Other	Moderate intensity aerobic exercise
Dietary AdvicesThe Obese adolescent children participated in the study received diet advices based on a balanced low calorie diet (1500 Kcal)	Other	Moderate intensity aerobic exercise, Virtual Reality Exercise
Virtual reality games exerciseVirtual reality games exercises 5 times per week for 12 weeks. Each participating child started the session with 5 minutes warming up exercises then followed by the main part which was consisted of 30 min of exercise where the child played the game using virtual reality X-Box and did different physical activities that included both the upper and lower extremities according to the game's requirements, and after that a 5 min cool-down part that involved some static flexibility exercises to allow the heart rate to lower, the total session that would be applied about 40 min (including 30 mins of Virtual reality exercises)	Other	Virtual Reality Exercise

Primary outcome

Body mass index
Time frame: From enrollment to the end of treatment at 12 weeks
It is the weight (in kilograms) divided by the height (in meter squares)
Serum triglycerides
Time frame: From enrollment to the end of treatment at 12 weeks
Level of triglycerides fats in blood in measured in laboratory using venous blood sample
Total Cholesterol
Time frame: From enrollment to the end of treatment at 12 weeks
Level of total cholesterol in blood in measured in laboratory using venous blood sample
High Density Lipoproteins (HDL)
Time frame: From enrollment to the end of treatment at 12 weeks
High Density Lipoproteins (HDL) cholesterol fats are measured in laboratory using a venous blood sample
Low Density Lipoproteins (LDL)
Time frame: From enrollment to the end of treatment at 12 weeks
Low Density Lipoproteins (LDL) cholesterol fats are measured in laboratory using a venous blood sample

1 secondary outcome

HDL ratio
Time frame: From enrollment to the end of treatment at 12 weeks

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 18 Jul 2025.

Related trials for Obese Children and Adolescents

Not yet recruiting
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
Binge Eating Disorder, Binge Eating
Not yet recruiting
Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)
Binge Eating, Overweight and Obesity
RecruitingPhase 3
A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults
Monogenic Obesity
Recruiting
SMART GOALS for Youth With Prediabetes
PreDiabetes, Adolescent Obesity
Active, not recruitingPhase 2
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic Obesity, Hypothalamic Tumor

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Radwa S Abdulrahman, PhD principal investigator

Ass. Prof. Dept. of PT for Pediatric, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

Hayam M Mahmoud, PhD study chair

Professor Dept. of PT for Neurology & Neurosurgery, Faculty of Physical Therapy, Cairo Univ. Egypt

Wael OA Abd El-Khalek, PhD study chair

Lecturer, Dept. of Basic Sciences, Faculty of Physical Therapy, Badr University in Cairo, Egypt.

2 sites in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 18 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Body mass index (time frame: From enrollment to the end of treatment at 12 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07073651.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jul 2025.