Presence of Missed Canalscone beam CTNCT07077694
Artificial Intelligence to Detect Missed Root Canals in Previously Treated Lower Back Teeth Using 3D Dental Imaging (CBCT)
A study testing Root Canal Retreatment in people with Presence of Missed Canals and Morphological Variation, run by Future University in Egypt at 1 site in Egypt.
Trial summary
Aims to detect the Accuracy of Artificial Intelligence Technology in Detecting the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar. Will Artificial intelligence software, CBCT and Clinical visual examination with dental operating microscope differs in the detection of presence of missed… Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Presence of Missed Canals, Morphological Variation
- What is being tested?
- Root Canal Retreatment
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 3 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Dec 2024to 29 Oct 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- 1) Patients must be medically free from any systemic disease that can affect root canal treatment.
- 2) Age range of the patient should be between 18 - 50 years old. 3) No sex predilection. 4) Patients must have good oral hygiene. 5) Patients with root canal-treated teeth. 6) Restorable teeth. 7) Positive patient acceptance for participating in the study. 8) Patients can sign informed consent.
Who cannot join
- 1) Patients with very poor oral hygiene. 2) Patients above 50 years and below 18 years. 3) Pregnant women after taking detailed history and pregnancy test must be in the first visit.
- 4) Psychologically disturbed patients. 5) Tooth periodontally affected with grade 2 or 3 mobility. 6) Non restorable teeth. 7) Tooth with abnormal anatomy and calcified canals.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Faculty of Oral and Dental Medicine future university
Cairo, Cairo Governorate, 11835
About this study
Official title: Accuracy of Artificial Intelligence Technology to Detect the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar : Diagnostic Accuracy Experimental Study
Aims to detect the Accuracy of Artificial Intelligence Technology in Detecting the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar. Will Artificial intelligence software, CBCT and Clinical visual examination with dental operating microscope differs in the detection of presence of missed canals of endodontically treated human mandibular second molar ?
- Conditions
- Presence of Missed Canals, Morphological Variation
- Being tested
- Root Canal Retreatment
- Keywords
- Morphological variation, Presence of missed canals, CBCT, AI, Artificial intelligence, Clinical visual examination, dental operating microscope, mandibular second molar
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Root Canal RetreatmentProcedure or surgery
Also called Re-RCT
if Retreatment was needed, local anesthesia using 1.8 ml (one cartridge) of 4% articaine with 1:100,000 epinephrine local anesthetic solution, administered with end -loading cartridge aspirating syringe and a 27-gauge long needle. Under rubber dam isolation, All carious tissue and existing coronal restorations were thoroughly removed using a round bur, an endodontic access cavity, canal preparation and removal of existing root canal filling, irrigation with 2.6% NAOCL and saline, determining the working length using apex locator and PA radiograph, to be 0.5 to 1 mm shorter than radiographic apex, Drying the canal with paper point and obturation to achieve a dense, well adapted Monoblock obturation. A post-obturation periapical radiograph was taken to confirm the quality of the fill in terms of length, density, then sealed by a temporary restorative material.
| Study group | Role | What they receive |
|---|---|---|
| Presence of missed canals | Active comparator | Not described Receives: Procedure: Root Canal Retreatment |
| Morphological variation | Active comparator | Not described Receives: Procedure: Root Canal Retreatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Presence of missed canals
Measured: Pre Operative and At the end of the treatment within 1 week
Secondary outcomes (1)
Morphological variation
Measured: Pre Operative and At the end of the treatment within 1 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jul 2025
- Study start25 Dec 2024
- Primary completion29 Oct 2025 (estimated)
- Study completion29 Oct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Presence of Missed CanalsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Sequential
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 3 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Future University in Egypt
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Baheej Ghazi H Alhazmi, Future University in Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07077694
- Sponsor's protocol ID
- FUE.REC(47)11-2024
- Acronym
- cone beam CT
- Status last verified
- Oct 2024
- First submitted
- 1 Jul 2025
- Last updated
- 22 Jul 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 22 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Accuracy of Artificial Intelligence Technology to Detect the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar : Diagnostic Accuracy Experimental Study
- ClinicalTrials.gov ID
- NCT07077694
- Acronym / sponsor ID
- cone beam CT / FUE.REC(47)11-2024
- Conditions
- Presence of Missed Canals, Morphological Variation
- Keywords
- Morphological variation, Presence of missed canals, CBCT, AI, Artificial intelligence, Clinical visual examination, dental operating microscope, mandibular second molar
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 3 participants (estimated)
- Lead sponsor
- Future University in EgyptUniversity, hospital or other
- Study start
- 25 Dec 2024 (actual)
- Primary completion
- 29 Oct 2025 (estimated)
- Study completion
- 29 Oct 2025 (estimated)
- First posted
- 22 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aims to detect the Accuracy of Artificial Intelligence Technology in Detecting the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar. Will Artificial intelligence software, CBCT and Clinical visual examination with dental operating microscope differs in the detection of presence of missed canals of endodontically treated human mandibular second molar ?
Study design
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Sequential
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Presence of missed canals | Active comparator | Procedure: Root Canal Retreatment |
| Morphological variation | Active comparator | Procedure: Root Canal Retreatment |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- 1) Patients must be medically free from any systemic disease that can affect root canal treatment.
- 2) Age range of the patient should be between 18 - 50 years old. 3) No sex predilection. 4) Patients must have good oral hygiene. 5) Patients with root canal-treated teeth. 6) Restorable teeth. 7) Positive patient acceptance for participating in the study. 8) Patients can sign informed consent.
Key exclusion criteria (2 listed)
- 1) Patients with very poor oral hygiene. 2) Patients above 50 years and below 18 years. 3) Pregnant women after taking detailed history and pregnancy test must be in the first visit.
- 4) Psychologically disturbed patients. 5) Tooth periodontally affected with grade 2 or 3 mobility. 6) Non restorable teeth. 7) Tooth with abnormal anatomy and calcified canals.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Root Canal RetreatmentAlso: Re-RCTif Retreatment was needed, local anesthesia using 1.8 ml (one cartridge) of 4% articaine with 1:100,000 epinephrine local anesthetic solution, administered with end -loading cartridge aspirating syringe and a 27-gauge long needle. Under rubber dam isolation, All carious tissue and existing coronal restorations were thoroughly removed using a round bur, an endodontic access cavity, canal preparation and removal of existing root canal filling, irrigation with 2.6% NAOCL and saline, determining the working length using apex locator and PA radiograph, to be 0.5 to 1 mm shorter than radiographic apex, Drying the canal with paper point and obturation to achieve a dense, well adapted Monoblock obturation. A post-obturation periapical radiograph was taken to confirm the quality of the fill in terms of length, density, then sealed by a temporary restorative material. | Procedure or surgery | Morphological variation, Presence of missed canals |
Primary outcome
Presence of missed canals
Time frame: Pre Operative and At the end of the treatment within 1 week
1 secondary outcome
Morphological variation
Time frame: Pre Operative and At the end of the treatment within 1 week
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jul 2025.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Root Canal Retreatment in people with Presence of Missed Canals and Morphological Variation, run by Future University in Egypt at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 22 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Presence of missed canals (time frame: Pre Operative and At the end of the treatment within 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jul 2025.