Peripheral BlocsNCT07077863
Transversus Abdominis Plane Block for Postoperative Pain Management in Gynaecological Cancer Surgery
An observational study of Peripheral Blocs, run by Duygu Akyol at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study was to compare the efficacy of transversus abdominis plane block for postoperative analgesia in gynaecological cancer surgery. The main question(s) aimed to be answered are: [For postoperative analgesia, a block performed by the surgeon in the area seen or a block performed by the anaesthetist… Read more about this study
- Who is it for?
- Ages 18 years and older, women only
- Conditions the study is for
- Peripheral Blocs
- How many people
- 100 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2024to 12 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Study population: Patients over 18 years of age who underwent surgery for gynaecological cancer between January 2024 and December 2024 and to whom we applied four quadrant transversus abdominis plane block (TAPB) from peripheral nerve blocks for postoperative analgesia were included in the stud
Who may be able to join
- - Women aged 18 and over
- Gynaecological cancer surgery
Who cannot join
- - Patients undergoing peripheral or central block in addition to transversus abdominis plane block
- Allergy or history of local anaesthetic drug allergy
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Basaksehir Cam and Sakura City Hospital
Istanbul
About this study
Official title: Transversus Abdominis Plane Block Applied by the Surgeon or Anaesthetist for Postoperative Pain Management in Gynaecological Cancer Surgery: a Retrospective Review
The aim of this study was to compare the efficacy of transversus abdominis plane block for postoperative analgesia in gynaecological cancer surgery.
The main question(s) aimed to be answered are:
[For postoperative analgesia, a block performed by the surgeon in the area seen or a block performed by the anaesthetist before surgery?] Patients undergoing gynaecological cancer surgery were retrospectively reviewed. The investigators evaluated the effect of a four-quadrant transversus abdominis plane block for postoperative analgesia on pain scores and postoperative opioid use.
Read the detailed description
This study was designed retrospectively. The investigators evaluated analgesia methods in patients undergoing surgery for gynaecological cancer between January 2024 and December 2024. The investigators evaluated the effect of transversus abdominis plane block on postoperative analgesia and opioid use.
- Conditions
- Peripheral Blocs
- Keywords
- gynecological cancer surgery, postoperative analgesia, transversus abdominis plane block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patients undergoing gynecologic cancer surgery | Patients undergoing transversus abominis plan block for postoperative analgesia |
What is being measured
The primary outcome is the main question the study is designed to answer.
postoperative numerical rating scale
Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.
Measured: 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jul 2025
- Study start1 Jan 2024
- Primary completion31 Dec 2024
- Study completion12 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Peripheral BlocsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Duygu Akyol
- Sponsor type
- Other government
- Responsible party
- Sponsor-investigator, Duygu Akyol, Bakirkoy Dr. Sadi Konuk Research and Training Hospital
- Investigators
- DUYGU AKYOL, M.D, Principal investigator, Başakşehir Çam & Sakura City Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07077863
- Sponsor's protocol ID
- 2025-58
- Status last verified
- Jul 2025
- First submitted
- 12 Jul 2025
- Last updated
- 23 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Ismail S, Siddiqui AS, Rehman A. Postoperative pain management practices and their effectiveness after major gynecological surgery: An observational study in a tertiary care hospital. J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):478-484. doi: 10.4103/joacp.JOACP_387_17.
PubMed 30774227Jakobsson J, Wickerts L, Forsberg S, Ledin G. Transversus abdominal plane (TAP) block for postoperative pain management: a review. F1000Res. 2015 Nov 26;4:F1000 Faculty Rev-1359. doi: 10.12688/f1000research.7015.1. eCollection 2015.
PubMed 26918134Bernard L, Lavecchia M, Trepanier G, Mah S, Pokoradi A, McGinnis JM, Alyafi M, Glezerson B, Nguyen J, Carlson V, Helpman L, Elit L, Jimenez W, Eiriksson L, Reade CJ. A double-blinded, randomized trial comparing surgeon-administered transversus abdominis plane block with placebo after midline laparotomy in gynecologic oncology surgery. Am J Obstet Gynecol. 2023 May;228(5):553.e1-553.e8. doi: 10.1016/j.ajog.2023.02.010. Epub 2023 Feb 14.
PubMed 36791986
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Transversus Abdominis Plane Block Applied by the Surgeon or Anaesthetist for Postoperative Pain Management in Gynaecological Cancer Surgery: a Retrospective Review
- ClinicalTrials.gov ID
- NCT07077863
- Acronym / sponsor ID
- 2025-58
- Conditions
- Peripheral Blocs
- Keywords
- gynecological cancer surgery, postoperative analgesia, transversus abdominis plane block
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Duygu AkyolOther government
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- 12 Jul 2025 (actual)
- First posted
- 22 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study was to compare the efficacy of transversus abdominis plane block for postoperative analgesia in gynaecological cancer surgery.
The main question(s) aimed to be answered are:
[For postoperative analgesia, a block performed by the surgeon in the area seen or a block performed by the anaesthetist before surgery?] Patients undergoing gynaecological cancer surgery were retrospectively reviewed. The investigators evaluated the effect of a four-quadrant transversus abdominis plane block for postoperative analgesia on pain scores and postoperative opioid use.
Detailed description
This study was designed retrospectively. The investigators evaluated analgesia methods in patients undergoing surgery for gynaecological cancer between January 2024 and December 2024. The investigators evaluated the effect of transversus abdominis plane block on postoperative analgesia and opioid use.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients undergoing gynecologic cancer surgery | – | –Patients undergoing transversus abominis plan block for postoperative analgesia |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients over 18 years of age who underwent surgery for gynaecological cancer between January 2024 and December 2024 and to whom we applied four quadrant transversus abdominis plane block (TAPB) from peripheral nerve blocks for postoperative analgesia were included in the stud
Key inclusion criteria (2 listed)
- - Women aged 18 and over
- Gynaecological cancer surgery
Key exclusion criteria (2 listed)
- - Patients undergoing peripheral or central block in addition to transversus abdominis plane block
- Allergy or history of local anaesthetic drug allergy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
postoperative numerical rating scale
Time frame: 24 hours postoperatively
Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2025.
- Results publication: PubMed 30774227Ismail S, Siddiqui AS, Rehman A. Postoperative pain management practices and their effectiveness after major gynecological surgery: An observational study in a tertiary care hospital. J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):478-484. doi: 10.4103/joacp.JOACP_387_17.
- Results publication: PubMed 26918134Jakobsson J, Wickerts L, Forsberg S, Ledin G. Transversus abdominal plane (TAP) block for postoperative pain management: a review. F1000Res. 2015 Nov 26;4:F1000 Faculty Rev-1359. doi: 10.12688/f1000research.7015.1. eCollection 2015.
- Results publication: PubMed 36791986Bernard L, Lavecchia M, Trepanier G, Mah S, Pokoradi A, McGinnis JM, Alyafi M, Glezerson B, Nguyen J, Carlson V, Helpman L, Elit L, Jimenez W, Eiriksson L, Reade CJ. A double-blinded, randomized trial comparing surgeon-administered transversus abdominis plane block with placebo after midline laparotomy in gynecologic oncology surgery. Am J Obstet Gynecol. 2023 May;228(5):553.e1-553.e8. doi: 10.1016/j.ajog.2023.02.010. Epub 2023 Feb 14.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
DUYGU AKYOL, M.D principal investigator
Başakşehir Çam & Sakura City Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Peripheral Blocs, run by Duygu Akyol at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
postoperative numerical rating scale (time frame: 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07077863, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2025.