Gynecologic CancersNCT07077889
Postoperative Chronic Pain in Gynaecological Cancer Surgery
An observational study of Gynecologic Cancers and Postoperative Pain, run by Duygu Akyol at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia. The main question(s) aimed to be answered are: [Which analgesia method has the lowest incidence of postoperative chronic pain?] Patients… Read more about this study
- Who is it for?
- Ages 18 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Gynecologic Cancers, Postoperative Pain
- How many people
- 500 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2024to 12 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: The incidence of postoperative chronic pain after surgery was evaluated in patients operated for gynaecological cancer between January 2024 and December 2025.
Who may be able to join
- Gynaecological cancer surgery
- >18 years
Who cannot join
- Incomplete or inadequate patient records
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Basaksehir Cam and Sakura City Hospital
Istanbul
About this study
Official title: Incidence and Risk Factors of Chronic Postoperative Pain in Gynaecological Cancer Surgery: a Retrospective Study
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
The main question(s) aimed to be answered are:
[Which analgesia method has the lowest incidence of postoperative chronic pain?] Patients undergoing gynaecological cancer surgery were retrospectively reviewed. The investigators evaluated the analgesia methods used for postoperative analgesia and the incidence of postoperative chronic pain.
Read the detailed description
This study was designed retrospectively. The investigators evaluated analgesia methods in patients undergoing surgery for gynaecological cancer between January 2024 and July 2025. In this study, the investigators planned to evaluate the incidence of postoperative chronic pain by evaluating patients for 3 months.
- Conditions
- Gynecologic Cancers, Postoperative Pain
- Keywords
- gynecological cancer surgery, chronic postoperative pain
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patients undergoing gynecologic cancer surgery | postoperative chronic pain in patients operated for gynaecological cancer |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of postoperative chronic pain
In our study, the investigators aimed to evaluate the incidence of postoperative chronic pain in patients operated for gynaecological cancer. for this purpose, postoperative patients were contacted at the end of 3 months and the presence of pain was evaluated.
Measured: 3 months postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jul 2025
- Study start1 Jan 2024
- Primary completion12 Jul 2025
- Study completion12 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Gynecologic CancersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 500 participants (actual)
Sponsor and investigators
- Lead sponsor
- Duygu Akyol
- Sponsor type
- Other government
- Responsible party
- Sponsor-investigator, Duygu Akyol, Bakirkoy Dr. Sadi Konuk Research and Training Hospital
- Investigators
- DUYGU AKYOL, M.D, Principal investigator, Başakşehir Çam & Sakura City Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07077889
- Sponsor's protocol ID
- 2025-221
- Status last verified
- Jan 2024
- First submitted
- 12 Jul 2025
- Last updated
- 25 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Ladjevic N, Milinic M, Jovanovic V, Jovicic J, Likic I, Ladjevic N. CHRONIC POSTOPERATIVE PAIN. Acta Clin Croat. 2023 Nov;62(Suppl4):88-96. doi: 10.20471/acc.2023.62.s4.13.
PubMed 40463450Gomez M, Izquierdo CE, Mayoral Rojals V, Pergolizzi J Jr, Plancarte Sanchez R, Paladini A, Varrassi G. Considerations for Better Management of Postoperative Pain in Light of Chronic Postoperative Pain: A Narrative Review. Cureus. 2022 Apr 2;14(4):e23763. doi: 10.7759/cureus.23763. eCollection 2022 Apr.
PubMed 35518528Lopes A, Seligman Menezes M, Antonio Moreira de Barros G. Chronic postoperative pain: ubiquitous and scarcely appraised: narrative review. Braz J Anesthesiol. 2021 Nov-Dec;71(6):649-655. doi: 10.1016/j.bjane.2020.10.014. Epub 2021 Feb 18.
PubMed 34715995Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain. 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384.
PubMed 30586067
Study at a glance
From the registry record, last updated by the sponsor on 25 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Incidence and Risk Factors of Chronic Postoperative Pain in Gynaecological Cancer Surgery: a Retrospective Study
- ClinicalTrials.gov ID
- NCT07077889
- Acronym / sponsor ID
- 2025-221
- Conditions
- Gynecologic Cancers, Postoperative Pain
- Keywords
- gynecological cancer surgery, chronic postoperative pain
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 500 participants (actual)
- Lead sponsor
- Duygu AkyolOther government
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 12 Jul 2025 (actual)
- Study completion
- 12 Jul 2025 (actual)
- First posted
- 22 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
The main question(s) aimed to be answered are:
[Which analgesia method has the lowest incidence of postoperative chronic pain?] Patients undergoing gynaecological cancer surgery were retrospectively reviewed. The investigators evaluated the analgesia methods used for postoperative analgesia and the incidence of postoperative chronic pain.
Detailed description
This study was designed retrospectively. The investigators evaluated analgesia methods in patients undergoing surgery for gynaecological cancer between January 2024 and July 2025. In this study, the investigators planned to evaluate the incidence of postoperative chronic pain by evaluating patients for 3 months.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients undergoing gynecologic cancer surgery | – | –postoperative chronic pain in patients operated for gynaecological cancer |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The incidence of postoperative chronic pain after surgery was evaluated in patients operated for gynaecological cancer between January 2024 and December 2025.
Key inclusion criteria (2 listed)
- Gynaecological cancer surgery
- >18 years
Key exclusion criteria (1 listed)
- Incomplete or inadequate patient records
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Incidence of postoperative chronic pain
Time frame: 3 months postoperatively
In our study, the investigators aimed to evaluate the incidence of postoperative chronic pain in patients operated for gynaecological cancer. for this purpose, postoperative patients were contacted at the end of 3 months and the presence of pain was evaluated.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jul 2025.
- Results publication: PubMed 40463450Ladjevic N, Milinic M, Jovanovic V, Jovicic J, Likic I, Ladjevic N. CHRONIC POSTOPERATIVE PAIN. Acta Clin Croat. 2023 Nov;62(Suppl4):88-96. doi: 10.20471/acc.2023.62.s4.13.
- Results publication: PubMed 35518528Gomez M, Izquierdo CE, Mayoral Rojals V, Pergolizzi J Jr, Plancarte Sanchez R, Paladini A, Varrassi G. Considerations for Better Management of Postoperative Pain in Light of Chronic Postoperative Pain: A Narrative Review. Cureus. 2022 Apr 2;14(4):e23763. doi: 10.7759/cureus.23763. eCollection 2022 Apr.
- Results publication: PubMed 34715995Lopes A, Seligman Menezes M, Antonio Moreira de Barros G. Chronic postoperative pain: ubiquitous and scarcely appraised: narrative review. Braz J Anesthesiol. 2021 Nov-Dec;71(6):649-655. doi: 10.1016/j.bjane.2020.10.014. Epub 2021 Feb 18.
- Results publication: PubMed 30586067Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain. 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
DUYGU AKYOL, M.D principal investigator
Başakşehir Çam & Sakura City Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Gynecologic Cancers and Postoperative Pain, run by Duygu Akyol at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of postoperative chronic pain (time frame: 3 months postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07077889, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jul 2025.