Smoking CessationNCT07079306
ChatGPT-Supported Text Messaging Program for Smoking Cessation
A study testing BeFree+Bot and BeFree in people with Smoking Cessation, run by George Washington University at 1 site in United States.
Trial summary
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree. The research will consist of a formative evaluation comparing quitting related outcomes among users of BeFree+Bot and BeFree. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Smoking Cessation
- What is being tested?
- BeFree+Bot and BeFree
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 180 participants
- Where
- 1 siteUnited States
- Study dates
- Oct 2026to 30 Oct 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- lives in the US
- smoked a cigarette within the last 7 days
- has a mobile phone
- willing to receive text messages about the health effects of smoking on their mobile phone for 30 days
- willing to set a quit date in the next 7 days
- not pregnant
Who cannot join
- none
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Prolific
Washington D.C., District of Columbia, 20052
About this study
Official title: Engagement and Satisfaction With a ChatGPT-Supported Text Messaging Program for Smoking Cessation
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree. The research will consist of a formative evaluation comparing quitting related outcomes among users of BeFree+Bot and BeFree.
- Conditions
- Smoking Cessation
- Being tested
- BeFree+Bot, BeFree
- Keywords
- smoking cessation, ai, text messaging
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
BeFree+BotBehavioural
Text messaging program called BeFree and access to BBot, ChatGPT chatbot
BeFreeBehavioural
Text messaging program called BeFree
| Study group | Role | What they receive |
|---|---|---|
| Intervention | Experimental | Text messages about quitting smoking and access to specialized ChatGPT chatbot Receives: Behavioral: BeFree+Bot |
| Control | Active comparator | Text messages about quitting smoking Receives: Behavioral: BeFree |
What is being measured
The primary outcome is the main question the study is designed to answer.
Continuous abstinence
the longest continuous period (in days) that you did not smoke a cigarette
Measured: at 1 month follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jul 2025
- Study startOct 2026 (estimated)
- Primary completion30 Mar 2027 (estimated)
- Study completion30 Oct 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Smoking CessationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 180 participants (estimated)
Sponsor and investigators
- Lead sponsor
- George Washington University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Lorien Abroms, George Washington University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07079306
- Sponsor's protocol ID
- GWUniversity
- Status last verified
- Oct 2026
- First submitted
- 14 Jul 2025
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: It is a small pilot study
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Engagement and Satisfaction With a ChatGPT-Supported Text Messaging Program for Smoking Cessation
- ClinicalTrials.gov ID
- NCT07079306
- Acronym / sponsor ID
- GWUniversity
- Conditions
- Smoking Cessation
- Keywords
- smoking cessation, ai, text messaging
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 180 participants (estimated)
- Lead sponsor
- George Washington UniversityUniversity, hospital or other
- Study start
- Oct 2026 (estimated)
- Primary completion
- 30 Mar 2027 (estimated)
- Study completion
- 30 Oct 2027 (estimated)
- First posted
- 23 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree. The research will consist of a formative evaluation comparing quitting related outcomes among users of BeFree+Bot and BeFree.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intervention | Experimental | Behavioral: BeFree+BotText messages about quitting smoking and access to specialized ChatGPT chatbot |
| Control | Active comparator | Behavioral: BeFreeText messages about quitting smoking |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- lives in the US
- smoked a cigarette within the last 7 days
- has a mobile phone
- willing to receive text messages about the health effects of smoking on their mobile phone for 30 days
- willing to set a quit date in the next 7 days
Key exclusion criteria (1 listed)
- none
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| BeFree+BotText messaging program called BeFree and access to BBot, ChatGPT chatbot | Behavioural | Intervention |
| BeFreeText messaging program called BeFree | Behavioural | Control |
Primary outcome
Continuous abstinence
Time frame: at 1 month follow-up
the longest continuous period (in days) that you did not smoke a cigarette
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
- Individual participant dataSharing planned: No. It is a small pilot study
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing BeFree+Bot and BeFree in people with Smoking Cessation, run by George Washington University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Lorien Abroms, ScD (202-994-3518, lorien@gwu.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Continuous abstinence (time frame: at 1 month follow-up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026; AzTrials last refreshed its copy on 26 Oct 2026.