Hip Fracture SurgeryNCT07081867
Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery
An observational study of Hip Fracture Surgery and Postoperative Pain Management, run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization at 1 site in Turkey (Türkiye).
Trial summary
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery. Both techniques are regional anesthesia methods aiming to reduce postoperative pain and opioid consumption. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia
- What is being tested?
- Supra-inguinal Fascia Iliaca Block (SIFIB) and Sacral Erector Spinae Plane Block (SESPB)
- Type of treatment
- Injection or infusion, Surgery or procedure
- How many people
- 77 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jan 2025to 1 Dec 2025
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Patients aged 65 years and older who underwent hip fracture surgery under spinal anesthesia at Prof. Dr. Cemil Taşçıoğlu City Hospital between January and June 2025. Only patients who provided written informed consent and met the inclusion criteria were enrolled.
Who may be able to join
- Patients aged 65 years and older
- Patients undergoing surgery for hip fractures under spinal anesthesia
- Patients who are oriented and cooperative
- Patients who have signed an informed consent form
Who cannot join
- Patients with contraindications for spinal anesthesia
- Patients with Alzheimer's disease or dementia, and those who are non-oriented or non-cooperative
- Patients with major organ failure (such as heart, liver, or kidney failure)
- Patients who decline to participate in the study
- Patients classified as American Society of Anesthesiologists (ASA) Physical Status IV or higher
- Patients with pathological fractures or bone metastasis
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Istanbul, Sisli, 34384
About this study
Official title: Comparison of Postoperative Analgesic Efficacy of Preoperatively Performed Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block in Patients Undergoing Surgery for Hip Fracture
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery. Both techniques are regional anesthesia methods aiming to reduce postoperative pain and opioid consumption. The study evaluates pain scores, opioid requirements, mobilization times, and hospital discharge times to determine which block provides more effective pain management in different postoperative periods.
Read the detailed description
Hip fractures are common injuries among elderly patients, often resulting in high rates of morbidity and mortality. Effective postoperative pain management plays a critical role in reducing complications such as delayed mobilization, deep vein thrombosis, pneumonia, and prolonged hospitalization.
Regional anesthesia techniques, including Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB), have gained popularity as part of multimodal analgesia strategies that aim to minimize opioid use and improve postoperative comfort. However, there is limited evidence comparing these two techniques directly.
In this prospective observational study, patients aged 65 and older undergoing hip fracture surgery under spinal anesthesia were included. After obtaining informed consent, patients received either SESPB or SIFIB for postoperative analgesia in addition to the standard anesthetic protocol.
Pain levels were assessed using the Visual Analog Scale (VAS) at 1, 6, 12, and 24 hours after surgery. Additional data such as total opioid consumption within 24 hours, time to first analgesic requirement, mobilization time, and length of hospital stay were recorded.
The results demonstrated that patients who received SIFIB had significantly lower pain scores in the early postoperative period (1st hour), while patients who received SESPB experienced better pain relief in the late postoperative period (24th hour). No significant differences were observed between the groups in terms of total opioid consumption, mobilization time, or hospital stay duration. No complications related to the block procedures were reported.
This study suggests that both SESPB and SIFIB are safe and effective regional anesthesia techniques for postoperative pain management in hip fracture surgeries. The selection between these blocks may be based on the desired onset and duration of analgesia, with SIFIB providing superior early pain control and SESPB offering more prolonged analgesic effects.
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Being tested
- Supra-inguinal Fascia Iliaca Block (SIFIB), Sacral Erector Spinae Plane Block (SESPB)
- Keywords
- Nerve Block, Anesthesia, Regional, Hip Fractures, Postoperative Pain, Analgesia, Visual Analog Scale, Pain Measurement
- Medical subject headings
- Hip Fractures, Pain, Postoperative, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Supra-inguinal Fascia Iliaca Block (SIFIB)Procedure or surgery
Ultrasound-guided injection of 40 mL of 0.25% bupivacaine between the iliacus muscle and fascia iliaca via a supra-inguinal approach, performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia.
Sacral Erector Spinae Plane Block (SESPB)Procedure or surgery
Ultrasound-guided injection of 40 mL of 0.25% bupivacaine into the fascial plane deep to the erector spinae muscle at the sacral level (S2), performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia.
| Study group | Role | What they receive |
|---|---|---|
| SIFIB Group | Patients who underwent Supra-Inguinal Fascia Iliaca Block (n=40) Receives: Procedure: Supra-inguinal Fascia Iliaca Block (SIFIB) | |
| SESPB Group | Patients who underwent Sacral Erector Spinae Plane Block (n=37) Receives: Procedure: Sacral Erector Spinae Plane Block (SESPB) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain Scores
Pain intensity measured using the Visual Analog Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Pain scores will be recorded at specific postoperative time points: 1st, 6th, 12th, and 24th hours.
Measured: At 1 hour, 6 hours, 12 hours, and 24 hours postoperatively.
Time to First Postoperative Analgesic Requirement
Time interval from end of surgery to the first request for analgesia.
Measured: Up to 48 hours postoperatively.
Total Postoperative Opioid Consumption
The total amount of opioids required by patients during the postoperative period.
Measured: A week
Time to First Mobilization
The time until patients' first mobilization (walking or standing) after surgery.
Measured: From the end of surgery until first mobilization, typically within 24 to 48 hours postoperatively
Secondary outcomes (2)
Length of Hospital Stay
Duration from the day of surgery to the day of hospital discharge, measured in calendar days.
Measured: Up to 14 days postoperatively.
Block-Related Complications
Possible complications following Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB), such as nerve injury, infection, hematoma, etc.
Measured: A week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jul 2025
- Study start15 Jan 2025
- Primary completion15 Jun 2025
- Study completion1 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hip Fracture SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 77 participants (actual)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Beyzanur Aydoğdu, Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Investigators
- Beyzanur Aydogdu, Principal investigator, Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07081867
- Sponsor's protocol ID
- CT-ERHO-AR-BA-01
- Status last verified
- Jan 2026
- First submitted
- 9 Jul 2025
- Last updated
- 23 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual patient data will not be shared due to patient privacy requirements and ethical board restrictions.
Study at a glance
From the registry record, last updated by the sponsor on 23 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Postoperative Analgesic Efficacy of Preoperatively Performed Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block in Patients Undergoing Surgery for Hip Fracture
- ClinicalTrials.gov ID
- NCT07081867
- Acronym / sponsor ID
- CT-ERHO-AR-BA-01
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Keywords
- Nerve Block, Anesthesia, Regional, Hip Fractures, Postoperative Pain, Analgesia, Visual Analog Scale, Pain Measurement
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 77 participants (actual)
- Lead sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital OrganizationUniversity, hospital or other
- Study start
- 15 Jan 2025 (actual)
- Primary completion
- 15 Jun 2025 (actual)
- Study completion
- 1 Dec 2025 (actual)
- First posted
- 23 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery. Both techniques are regional anesthesia methods aiming to reduce postoperative pain and opioid consumption. The study evaluates pain scores, opioid requirements, mobilization times, and hospital discharge times to determine which block provides more effective pain management in different postoperative periods.
Detailed description
Hip fractures are common injuries among elderly patients, often resulting in high rates of morbidity and mortality. Effective postoperative pain management plays a critical role in reducing complications such as delayed mobilization, deep vein thrombosis, pneumonia, and prolonged hospitalization.
Regional anesthesia techniques, including Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB), have gained popularity as part of multimodal analgesia strategies that aim to minimize opioid use and improve postoperative comfort. However, there is limited evidence comparing these two techniques directly.
In this prospective observational study, patients aged 65 and older undergoing hip fracture surgery under spinal anesthesia were included. After obtaining informed consent, patients received either SESPB or SIFIB for postoperative analgesia in addition to the standard anesthetic protocol.
Pain levels were assessed using the Visual Analog Scale (VAS) at 1, 6, 12, and 24 hours after surgery. Additional data such as total opioid consumption within 24 hours, time to first analgesic requirement, mobilization time, and length of hospital stay were recorded.
The results demonstrated that patients who received SIFIB had significantly lower pain scores in the early postoperative period (1st hour), while patients who received SESPB experienced better pain relief in the late postoperative period (24th hour). No significant differences were observed between the groups in terms of total opioid consumption, mobilization time, or hospital stay duration. No complications related to the block procedures were reported.
This study suggests that both SESPB and SIFIB are safe and effective regional anesthesia techniques for postoperative pain management in hip fracture surgeries. The selection between these blocks may be based on the desired onset and duration of analgesia, with SIFIB providing superior early pain control and SESPB offering more prolonged analgesic effects.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| SIFIB Group | – | Procedure: Supra-inguinal Fascia Iliaca Block (SIFIB)Patients who underwent Supra-Inguinal Fascia Iliaca Block (n=40) |
| SESPB Group | – | Procedure: Sacral Erector Spinae Plane Block (SESPB)Patients who underwent Sacral Erector Spinae Plane Block (n=37) |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Patients aged 65 years and older who underwent hip fracture surgery under spinal anesthesia at Prof. Dr. Cemil Taşçıoğlu City Hospital between January and June 2025. Only patients who provided written informed consent and met the inclusion criteria were enrolled.
Key inclusion criteria (4 listed)
- Patients aged 65 years and older
- Patients undergoing surgery for hip fractures under spinal anesthesia
- Patients who are oriented and cooperative
- Patients who have signed an informed consent form
Key exclusion criteria (6 listed)
- Patients with contraindications for spinal anesthesia
- Patients with Alzheimer's disease or dementia, and those who are non-oriented or non-cooperative
- Patients with major organ failure (such as heart, liver, or kidney failure)
- Patients who decline to participate in the study
- Patients classified as American Society of Anesthesiologists (ASA) Physical Status IV or higher
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Supra-inguinal Fascia Iliaca Block (SIFIB)Ultrasound-guided injection of 40 mL of 0.25% bupivacaine between the iliacus muscle and fascia iliaca via a supra-inguinal approach, performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia. | Procedure or surgery | SIFIB Group |
| Sacral Erector Spinae Plane Block (SESPB)Ultrasound-guided injection of 40 mL of 0.25% bupivacaine into the fascial plane deep to the erector spinae muscle at the sacral level (S2), performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia. | Procedure or surgery | SESPB Group |
Primary outcome
Postoperative Pain Scores
Time frame: At 1 hour, 6 hours, 12 hours, and 24 hours postoperatively.
Pain intensity measured using the Visual Analog Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Pain scores will be recorded at specific postoperative time points: 1st, 6th, 12th, and 24th hours.
Time to First Postoperative Analgesic Requirement
Time frame: Up to 48 hours postoperatively.
Time interval from end of surgery to the first request for analgesia.
Total Postoperative Opioid Consumption
Time frame: A week
The total amount of opioids required by patients during the postoperative period.
Time to First Mobilization
Time frame: From the end of surgery until first mobilization, typically within 24 to 48 hours postoperatively
The time until patients' first mobilization (walking or standing) after surgery.
2 secondary outcomes
Length of Hospital Stay
Time frame: Up to 14 days postoperatively.
Block-Related Complications
Time frame: A week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jan 2026.
- Individual participant dataSharing planned: No. Individual patient data will not be shared due to patient privacy requirements and ethical board restrictions.
Related trials for Hip Fracture Surgery
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Effect of Ondansetron on the Incidence of Spinal Anaesthesia-Induced Hypotension in Elderly Patients Undergoing Fracture Hip Surgery
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Lumbar Erector Spinae Plane Block Versus PENG Block for Hip Fracture Surgery
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Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery
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A Decision Support Tool for Common Surgical Fixations of Hip Fractures
Hip Fracture Surgeries, High Risk Population of Hip Fractures
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Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Beyzanur Aydogdu principal investigator
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hip Fracture Surgery and Postoperative Pain Management, run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain Scores (time frame: At 1 hour, 6 hours, 12 hours, and 24 hours postoperatively.). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jan 2026.