MenopauseNCT07085078
Progressive Relaxation Exercise, Menopausal Symptoms and Working Performance
A study testing progressive relaxation exercises in people with Menopause and Menopause Related Conditions, run by Aydin Adnan Menderes University at 2 sites in Turkey (Türkiye).
Trial summary
Women typically enter menopause between the ages of 40 and 47, and they spend approximately one-third of their lives in this phase. During menopause, many experience hot flashes due to decreased estrogen levels, along with vasomotor changes such as altered heart rhythms and sleep disturbances. Read more about this study
- Who is it for?
- Ages 45 to 65 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Menopause, Menopause Related Conditions
- What is being tested?
- progressive relaxation exercises
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 106 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 30 Apr 2025to 30 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 65 years
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Being a woman between the ages of 45-65
- Being able to read and understand Turkish
- Being at least a primary school graduate
- Not having menstruation for a year
Who cannot join
- Having a disability in maintaining communication (such as hearing and speaking)
- Having entered early menopause (no menstruation) through surgery or natural means,
- Being on hormone therapy
- Filling out forms incompletely
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Bursa Uludag University
Bursa, 16059
Bursa Uludağ Üniversitesi
Nilufer, Bursa, 16059
About this study
Official title: Effects of Progressive Relaxation Exercise on Menopausal Symptoms and Work Performance: A Randomized Control Study
Women typically enter menopause between the ages of 40 and 47, and they spend approximately one-third of their lives in this phase. During menopause, many experience hot flashes due to decreased estrogen levels, along with vasomotor changes such as altered heart rhythms and sleep disturbances. These issues may accompany or occur independently of hot flashes. Additionally, psychological changes can arise, including tension, sudden mood swings, anxiety, stress, and depression. Physiological concerns may include vaginal atrophy and stress incontinence.
Read the detailed description
Previous studies have shown that menopausal symptoms can significantly increase women's social appearance anxiety, depression, stress, and anxiety overall, negatively impacting their quality of life. Moreover, a limited number of recent studies have attempted to explore the relationship between the severity of menopausal symptoms in the workplace and factors such as job performance, career development decisions, and overall work participation.
This study aims to investigate the effects of progressive relaxation exercises on women's menopausal symptoms and their work performance.
- Conditions
- Menopause, Menopause Related Conditions
- Being tested
- progressive relaxation exercises
- Keywords
- menophose, work performance, progressive relaxation, menopausal symptoms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
progressive relaxation exercisesBehavioural
Participants with menopausal symptoms received progressive relaxation exercise training, led by the responsible researcher who assigned them to the experimental group.
| Study group | Role | What they receive |
|---|---|---|
| Education | Experimental | Progressive relaxation exercis Receives: Behavioral: progressive relaxation exercises |
| Control | No intervention | Participants with menopausal symptoms assigned to the control group will not receive any intervention. They are expected to answer the scale questions used in the study. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Personal information form before intervention
Evaluation of women using personal information.
This tool includes questions on women's sociodemographic characteristics
Measured: Day 1 (During recruitment)
Before intervention, menopausal symptoms
Evaluation of menopausal symptoms with Menopause Rating Scale (MRS). It is a Likert-type scale consisting of 11 items, including menopausal complaints. For each item, there are options of "0= None", "1= Mild", "2= Moderate", "3= Severe", and "4= Very severe". The lowest possible score is 0, the highest score is 44. An increase in the total score obtained from the scale indicates an increase in the severity of the complaints experienced.
Measured: Day 1 (during recruitment)
Before intervention, Individual work performance
Before intervention, participants are evaluated with the "Individual Work Performance Questionnaire"The scale was designed to measure job performance perception. It consists of 18 Likert-type items. A high score on the scale indicates that job performance perception has increased.
Measured: Day 1 (During recruitment)
Secondary outcomes (2)
After intervention, menopausal symptoms
Evaluation of menopausal symptoms with Menopause Rating Scale (MRS). (The lowest possible score is 0, the highest score is 44. The increase in the total score obtained from the scale indicates an increase in the severity of the complaints).
Measured: Ten days after the conclusion of the five-week training program.
After intervention, Individual work performance
participants are evaluated with the "Individual Work Performance Questionnaire" (The scale was designed to measure job performance perception. It consists of 18 Likert-type items. A high score on the scale indicates that job performance perception has increased.)
Measured: Ten days after the conclusion of the five-week training program.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jul 2025
- Study start30 Apr 2025
- Primary completion30 Sep 2025
- Study completion30 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for MenopauseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Care provider, Outcomes assessor
- Enrolment
- 106 participants (actual)
Sponsor and investigators
- Lead sponsor
- Aydin Adnan Menderes University
- Sponsor type
- University, hospital or other
- Collaborators
- Uludag University
- Responsible party
- Principal investigator, Gonca Buran, Aydin Adnan Menderes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07085078
- Sponsor's protocol ID
- 18/17
- Status last verified
- May 2026
- First submitted
- 26 Jun 2025
- Last updated
- 27 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The responsible researcher will apply the training and exercises and code the data as A and B. A and B will be coded as A and B. The second researcher will apply the question and scale forms coded as A and B. The third researcher will not know which group the A and B data belong to, and the data will be entered into the SPSS program as A and B groups. The analyses will be carried out by the researcher who is blind to the groups. After the analyses are completed, all researchers will know which arm the findings belong to A and B groups. They will be able to access all of the data.
Publications
O'Neill MT, Jones V, Reid A. Impact of menopausal symptoms on work and careers: a cross-sectional study. Occup Med (Lond). 2023 Sep 29;73(6):332-338. doi: 10.1093/occmed/kqad078.
PubMed 37542726Koopmans L, Bernaards CM, Hildebrandt VH, Lerner D, de Vet HC, van der Beek AJ. Cross-cultural adaptation of the Individual Work Performance Questionnaire. Work. 2015;53(3):609-19. doi: 10.3233/WOR-152237.
PubMed 26835864
Study at a glance
From the registry record, last updated by the sponsor on 27 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Progressive Relaxation Exercise on Menopausal Symptoms and Work Performance: A Randomized Control Study
- ClinicalTrials.gov ID
- NCT07085078
- Acronym / sponsor ID
- 18/17
- Conditions
- Menopause, Menopause Related Conditions
- Keywords
- menophose, work performance, progressive relaxation, menopausal symptoms
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 106 participants (actual)
- Lead sponsor
- Aydin Adnan Menderes UniversityUniversity, hospital or other
- Collaborators
- Uludag University
- Study start
- 30 Apr 2025 (actual)
- Primary completion
- 30 Sep 2025 (actual)
- Study completion
- 30 Dec 2025 (actual)
- First posted
- 25 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Women typically enter menopause between the ages of 40 and 47, and they spend approximately one-third of their lives in this phase. During menopause, many experience hot flashes due to decreased estrogen levels, along with vasomotor changes such as altered heart rhythms and sleep disturbances. These issues may accompany or occur independently of hot flashes. Additionally, psychological changes can arise, including tension, sudden mood swings, anxiety, stress, and depression. Physiological concerns may include vaginal atrophy and stress incontinence.
Detailed description
Previous studies have shown that menopausal symptoms can significantly increase women's social appearance anxiety, depression, stress, and anxiety overall, negatively impacting their quality of life. Moreover, a limited number of recent studies have attempted to explore the relationship between the severity of menopausal symptoms in the workplace and factors such as job performance, career development decisions, and overall work participation.
This study aims to investigate the effects of progressive relaxation exercises on women's menopausal symptoms and their work performance.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Education | Experimental | Behavioral: progressive relaxation exercisesProgressive relaxation exercis |
| Control | No intervention | –Participants with menopausal symptoms assigned to the control group will not receive any intervention. They are expected to answer the scale questions used in the study. |
Who may qualify
- Ages
- 45 to 65 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Being a woman between the ages of 45-65
- Being able to read and understand Turkish
- Being at least a primary school graduate
- Not having menstruation for a year
Key exclusion criteria (4 listed)
- Having a disability in maintaining communication (such as hearing and speaking)
- Having entered early menopause (no menstruation) through surgery or natural means,
- Being on hormone therapy
- Filling out forms incompletely
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| progressive relaxation exercisesParticipants with menopausal symptoms received progressive relaxation exercise training, led by the responsible researcher who assigned them to the experimental group. | Behavioural | Education |
Primary outcome
Personal information form before intervention
Time frame: Day 1 (During recruitment)
Evaluation of women using personal information. This tool includes questions on women's sociodemographic characteristics
Before intervention, menopausal symptoms
Time frame: Day 1 (during recruitment)
Evaluation of menopausal symptoms with Menopause Rating Scale (MRS). It is a Likert-type scale consisting of 11 items, including menopausal complaints. For each item, there are options of "0= None", "1= Mild", "2= Moderate", "3= Severe", and "4= Very severe". The lowest possible score is 0, the highest score is 44. An increase in the total score obtained from the scale indicates an increase in the severity of the complaints experienced.
Before intervention, Individual work performance
Time frame: Day 1 (During recruitment)
Before intervention, participants are evaluated with the "Individual Work Performance Questionnaire"The scale was designed to measure job performance perception. It consists of 18 Likert-type items. A high score on the scale indicates that job performance perception has increased.
2 secondary outcomes
After intervention, menopausal symptoms
Time frame: Ten days after the conclusion of the five-week training program.
After intervention, Individual work performance
Time frame: Ten days after the conclusion of the five-week training program.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 May 2026.
- Results publication: PubMed 37542726O'Neill MT, Jones V, Reid A. Impact of menopausal symptoms on work and careers: a cross-sectional study. Occup Med (Lond). 2023 Sep 29;73(6):332-338. doi: 10.1093/occmed/kqad078.
- Results publication: PubMed 26835864Koopmans L, Bernaards CM, Hildebrandt VH, Lerner D, de Vet HC, van der Beek AJ. Cross-cultural adaptation of the Individual Work Performance Questionnaire. Work. 2015;53(3):609-19. doi: 10.3233/WOR-152237.
- Individual participant dataSharing planned: Yes. The responsible researcher will apply the training and exercises and code the data as A and B. A and B will be coded as A and B. The second researcher will apply the question and scale forms coded as A and B. The third researcher will not know which group the A and B data belong to, and the data will be entered into the SPSS program as A and B groups. The analyses will be carried out by the researcher who is blind to the groups. After the analyses are completed, all researchers will know which arm the findings belong to A and B groups. They will be able to access all of the data.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing progressive relaxation exercises in people with Menopause and Menopause Related Conditions, run by Aydin Adnan Menderes University at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Personal information form before intervention (time frame: Day 1 (During recruitment)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07085078, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 May 2026.