Underage DrinkingNCT07086508
Examining an Intervention to Reduce High School Drinking
A study testing e-CHECKUP TO GO (eCTG) and e-Parent Intervention in people with Underage Drinking and Drinking, Teen, run by Binghamton University at 1 site in United States.
Trial summary
Underage drinking is a significant problem in the United States. While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research shows drinking by older high schoolers is problematic and interventions for older high… Read more about this study
- Who is it for?
- Ages 15 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
- What is being tested?
- e-CHECKUP TO GO (eCTG) and e-Parent Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 2,532 participants
- Where
- 1 siteUnited States
- Study dates
- 13 Mar 2026to Sep 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 65 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Teen is aged 15-18/Parent has a teen aged 15-18
- Parent and teen both consent (forming a dyad testing unit)
- They are part of Ipsos' Knowledge Panel
Who cannot join
- Outside of the teen age range/Parent does not have a teen aged 15-18
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Binghamton University
Binghamton, New York, 13902
Nadine Mastroleo, PhD, 607-777-4369, nmastrol@binghamton.edu
About this study
Official title: A Randomized Clinical Trial: Examining the Efficacy of eCHECKUP TO GO Combined With a Brief Parent-based Intervention to Reduce High School Student Drinking
Underage drinking is a significant problem in the United States. While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research shows drinking by older high schoolers is problematic and interventions for older high schoolers remain limited. The current project will test the efficacy of the e-CHECKUP TO GO (eCTG), alone and combined with an electronic-Parent-Based Intervention (ePBI), for junior and senior high school students using a nationally representative sample with the goal of reducing alcohol use and negative consequences.
Read the detailed description
Prevalence rates of high school alcohol use suggest 61.6% of high school students have used alcohol by their senior year and 1 in 3 students report alcohol use past 30-days. High school risky drinking is associated with negative consequences including impaired neurocognitive functioning, academic problems, hangovers, passing out, unwanted sex, dating violence, suicide attempts, illicit drug use, riding with impaired drivers, and impaired driving.
While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research shows drinking by older high schoolers is problematic and interventions for older high schoolers remain limited. Implementation with high schoolers has always been difficult to sustain following the completion of the grant funding period due to large costs associated with personnel to hire, train, and supervise teachers and staff to implement interventions with fidelity. As an alternative, brief web-based personalized feedback interventions that do not require staffing or costs to implement to large numbers of students have shown promise (e.g., eCHECKUP TO GO; eCTG). Our preliminary work, including our funded NIAAA R21 study, supporting this proposal has shown eCTG is efficacious in changing normative perceptions of peer drinking frequency and drunkenness, positive alcohol expectancies, and reducing both alcohol use and consequences among high school students. The proposed research will expand on these findings by conducting a randomized controlled trial using the eCHECKUP TO GO (eCTG) alone and combined with an efficacious brief electronic-Parent-Based Intervention on a nationally representative sample of high school juniors and seniors.
The design is a four-arm RCT: eCTG, eCTG+, Parent-Only, and Control. Data collection will occur across 5 waves (pre-intervention baseline, 3-, 6-, 9-, 12- month follow-ups) for all arms. In all arms there is one wave for parents (3-month only).
- Conditions
- Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
- Being tested
- e-CHECKUP TO GO (eCTG), e-Parent Intervention
- Keywords
- Underage drinking, Teen Alcohol Use
- Medical subject headings
- Underage Drinking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
e-CHECKUP TO GO (eCTG)Behavioural
A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol.
e-Parent InterventionBehavioural
The e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens.
| Study group | Role | What they receive |
|---|---|---|
| e-CHECKUP TO GO (eCTG) | Experimental | A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol Receives: Behavioral: e-CHECKUP TO GO (eCTG) |
| e-Parent Intervention and eCTG (eCTG+) | Experimental | The eCTG+ is a combination of the eCTG and the e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens. Receives: Behavioral: e-CHECKUP TO GO (eCTG); Behavioral: e-Parent Intervention |
| e-Parent Intervention | Experimental | The e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens. Receives: Behavioral: e-Parent Intervention |
| Control | No intervention | No intervention is provided |
What is being measured
The primary outcome is the main question the study is designed to answer.
Examine changes in alcohol use
A standard drink definition will be provided, indicating that a standard drink consists of 12 oz. of beer or wine cooler, 8.5 oz. of malt liquor, 4 oz. of wine, or 1.5 oz. of hard liquor. Using the Daily Drinking Questionnaire (DDQ), participants will indicate how many drinks they consumed on each day of a typical week during the past month. Participants will also be asked peak drinks and hours spent drinking during the occasion they drank the most during the past month.
Measured: Baseline, 3 month, 6 month, 9 month, 12 month
Secondary outcomes (1)
Examine Changes in Consequences of Alcohol Use
Alcohol-related consequences (e.g., said or done embarrassing things, blackout) from the past three months will be measured using the established Brief Young Adult Alcohol Consequences Questionnaire (BYAACQ). Response options will be measured on a 7-point scale ranging from (0) no, not in the past year to (6) 11 or more times in the past three months.
Measured: Baseline, 3 month, 6 month, 9 month, 12 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jul 2025
- Study start13 Mar 2026
- Primary completionSep 2028 (estimated)
- Study completionSep 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Underage DrinkingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The first group receives the e-CTG, the second group receives the e-CTG+, the third group receives the e-PBI, and the final group is control.
- Masking
- None (open label)
- Enrolment
- 2,532 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Binghamton University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nadine Mastroleo, Binghamton University
- Investigators
- Nadine Mastroleo, PhD, Principal investigator, Binghamton University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07086508
- Sponsor's protocol ID
- STUDY00006200
- Status last verified
- Jul 2026
- First submitted
- 18 Jul 2025
- Last updated
- 3 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: As part of funding requirements, data collected will be submitted to the NIAAA Data Archive.
Publications
van der Vorst H, Engels RC, Meeus W, Dekovic M. Parental attachment, parental control, and early development of alcohol use: a longitudinal study. Psychol Addict Behav. 2006 Jun;20(2):107-16. doi: 10.1037/0893-164X.20.2.107.
PubMed 16784352Collins RL, Parks GA, Marlatt GA. Social determinants of alcohol consumption: the effects of social interaction and model status on the self-administration of alcohol. J Consult Clin Psychol. 1985 Apr;53(2):189-200. doi: 10.1037//0022-006x.53.2.189. No abstract available.
PubMed 3998247Read JP, Kahler CW, Strong DR, Colder CR. Development and preliminary validation of the young adult alcohol consequences questionnaire. J Stud Alcohol. 2006 Jan;67(1):169-77. doi: 10.15288/jsa.2006.67.169.
PubMed 16536141
Study at a glance
From the registry record, last updated by the sponsor on 3 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Clinical Trial: Examining the Efficacy of eCHECKUP TO GO Combined With a Brief Parent-based Intervention to Reduce High School Student Drinking
- ClinicalTrials.gov ID
- NCT07086508
- Acronym / sponsor ID
- STUDY00006200
- Conditions
- Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
- Keywords
- Underage drinking, Teen Alcohol Use
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 2,532 participants (estimated)
- Lead sponsor
- Binghamton UniversityUniversity, hospital or other
- Study start
- 13 Mar 2026 (actual)
- Primary completion
- Sep 2028 (estimated)
- Study completion
- Sep 2028 (estimated)
- First posted
- 25 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Underage drinking is a significant problem in the United States. While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research shows drinking by older high schoolers is problematic and interventions for older high schoolers remain limited. The current project will test the efficacy of the e-CHECKUP TO GO (eCTG), alone and combined with an electronic-Parent-Based Intervention (ePBI), for junior and senior high school students using a nationally representative sample with the goal of reducing alcohol use and negative consequences.
Detailed description
Prevalence rates of high school alcohol use suggest 61.6% of high school students have used alcohol by their senior year and 1 in 3 students report alcohol use past 30-days. High school risky drinking is associated with negative consequences including impaired neurocognitive functioning, academic problems, hangovers, passing out, unwanted sex, dating violence, suicide attempts, illicit drug use, riding with impaired drivers, and impaired driving.
While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research shows drinking by older high schoolers is problematic and interventions for older high schoolers remain limited. Implementation with high schoolers has always been difficult to sustain following the completion of the grant funding period due to large costs associated with personnel to hire, train, and supervise teachers and staff to implement interventions with fidelity. As an alternative, brief web-based personalized feedback interventions that do not require staffing or costs to implement to large numbers of students have shown promise (e.g., eCHECKUP TO GO; eCTG). Our preliminary work, including our funded NIAAA R21 study, supporting this proposal has shown eCTG is efficacious in changing normative perceptions of peer drinking frequency and drunkenness, positive alcohol expectancies, and reducing both alcohol use and consequences among high school students. The proposed research will expand on these findings by conducting a randomized controlled trial using the eCHECKUP TO GO (eCTG) alone and combined with an efficacious brief electronic-Parent-Based Intervention on a nationally representative sample of high school juniors and seniors.
The design is a four-arm RCT: eCTG, eCTG+, Parent-Only, and Control. Data collection will occur across 5 waves (pre-intervention baseline, 3-, 6-, 9-, 12- month follow-ups) for all arms. In all arms there is one wave for parents (3-month only).
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- The first group receives the e-CTG, the second group receives the e-CTG+, the third group receives the e-PBI, and the final group is control.
| Arm | Type | Receives |
|---|---|---|
| e-CHECKUP TO GO (eCTG) | Experimental | Behavioral: e-CHECKUP TO GO (eCTG)A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol |
| e-Parent Intervention and eCTG (eCTG+) | Experimental | Behavioral: e-CHECKUP TO GO (eCTG), Behavioral: e-Parent InterventionThe eCTG+ is a combination of the eCTG and the e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens. |
| e-Parent Intervention | Experimental | Behavioral: e-Parent InterventionThe e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens. |
| Control | No intervention | –No intervention is provided |
Who may qualify
- Ages
- 15 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (3 listed)
- Teen is aged 15-18/Parent has a teen aged 15-18
- Parent and teen both consent (forming a dyad testing unit)
- They are part of Ipsos' Knowledge Panel
Key exclusion criteria (1 listed)
- Outside of the teen age range/Parent does not have a teen aged 15-18
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| e-CHECKUP TO GO (eCTG)A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol. | Behavioural | e-CHECKUP TO GO (eCTG), e-Parent Intervention and eCTG (eCTG+) |
| e-Parent InterventionThe e-Parent Intervention, which is an electronic handbook developed by Rob Turrisi to guide parents in discussing drinking, behaviors, and consequences with their teens. | Behavioural | e-Parent Intervention, e-Parent Intervention and eCTG (eCTG+) |
Primary outcome
Examine changes in alcohol use
Time frame: Baseline, 3 month, 6 month, 9 month, 12 month
A standard drink definition will be provided, indicating that a standard drink consists of 12 oz. of beer or wine cooler, 8.5 oz. of malt liquor, 4 oz. of wine, or 1.5 oz. of hard liquor. Using the Daily Drinking Questionnaire (DDQ), participants will indicate how many drinks they consumed on each day of a typical week during the past month. Participants will also be asked peak drinks and hours spent drinking during the occasion they drank the most during the past month.
1 secondary outcome
Examine Changes in Consequences of Alcohol Use
Time frame: Baseline, 3 month, 6 month, 9 month, 12 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Aug 2026.
- Background: PubMed 16784352van der Vorst H, Engels RC, Meeus W, Dekovic M. Parental attachment, parental control, and early development of alcohol use: a longitudinal study. Psychol Addict Behav. 2006 Jun;20(2):107-16. doi: 10.1037/0893-164X.20.2.107.
- Background: PubMed 3998247Collins RL, Parks GA, Marlatt GA. Social determinants of alcohol consumption: the effects of social interaction and model status on the self-administration of alcohol. J Consult Clin Psychol. 1985 Apr;53(2):189-200. doi: 10.1037//0022-006x.53.2.189. No abstract available.
- Background: PubMed 16536141Read JP, Kahler CW, Strong DR, Colder CR. Development and preliminary validation of the young adult alcohol consequences questionnaire. J Stud Alcohol. 2006 Jan;67(1):169-77. doi: 10.15288/jsa.2006.67.169.
- Individual participant dataSharing planned: Yes. As part of funding requirements, data collected will be submitted to the NIAAA Data Archive.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nadine Mastroleo, PhD principal investigator
Binghamton University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing e-CHECKUP TO GO (eCTG) and e-Parent Intervention in people with Underage Drinking and Drinking, Teen, run by Binghamton University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nadine Mastroleo, PhD (607-777-4369, nmastrol@binghamton.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Examine changes in alcohol use (time frame: Baseline, 3 month, 6 month, 9 month, 12 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07086508, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Aug 2026.