Borderline Personality Disorder (BPD)NCT07091409
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
An observational study of Borderline Personality Disorder (BPD), run by Charite University, Berlin, Germany at 1 site in Germany.
Trial summary
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Borderline Personality Disorder (BPD)
- How many people
- 64 participants
- Where
- 1 siteGermany
- Study dates
- 1 Oct 2024to 20 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: BPD diagnosis and healthy participants
Who may be able to join
- BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior
Who cannot join
- neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months
Trial locations and contacts
1 site in 1 country.
About this study
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
Read the detailed description
We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations.
We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD.
In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.
- Conditions
- Borderline Personality Disorder (BPD)
- Medical subject headings
- Borderline Personality Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patients with BPD | Not described | |
| Healthy individuals | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of accidental harm scenarios misclassified as intentional
Accuracy
Measured: 20 Minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jul 2025
- Study start1 Oct 2024
- Primary completion20 Jul 2025
- Study completion20 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Borderline Personality Disorder (BPD)Studies of the same condition, open and under way.
- More trials run by Charite University, Berlin, GermanyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 64 participants (actual)
Sponsor and investigators
- Lead sponsor
- Charite University, Berlin, Germany
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Katja Wingenfeld, Charite University, Berlin, Germany
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07091409
- Sponsor's protocol ID
- BDP-MoDe
- Status last verified
- Oct 2024
- First submitted
- 22 Jul 2025
- Last updated
- 29 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
- ClinicalTrials.gov ID
- NCT07091409
- Acronym / sponsor ID
- BDP-MoDe
- Conditions
- Borderline Personality Disorder (BPD)
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 64 participants (actual)
- Lead sponsor
- Charite University, Berlin, GermanyUniversity, hospital or other
- Study start
- 1 Oct 2024 (actual)
- Primary completion
- 20 Jul 2025 (actual)
- Study completion
- 20 Jul 2025 (actual)
- First posted
- 29 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
Detailed description
We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations.
We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD.
In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patients with BPD | – | – |
| Healthy individuals | – | – |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- BPD diagnosis and healthy participants
Key inclusion criteria (1 listed)
- BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior
Key exclusion criteria (1 listed)
- neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of accidental harm scenarios misclassified as intentional
Time frame: 20 Minutes
Accuracy
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Borderline Personality Disorder (BPD), run by Charite University, Berlin, Germany at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of accidental harm scenarios misclassified as intentional (time frame: 20 Minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2025; AzTrials last refreshed its copy on 8 Nov 2026.