StrokeNCT07091708
EFFECT OF ELECTROACUPUNCTURE ON COMPLEX REGIONAL PAIN SYNDROME IN PATIENTS WITH STROKE: A RANDOMIZED CONTROLLED TRIAL
A study testing Acupuncture in people with Stroke, run by Cairo University.
Trial summary
Complex regional pain syndrome (CRPS) is a condition marked by pain that may occur spontaneously or in response to stimuli, often disproportionate to the initial injury.(Chae, 2010). In post-stroke complex regional pain syndrome, patients often have simultaneous shoulder and wrist pain. Read more about this study
- Who is it for?
- Ages 45 to 60 years
- Conditions the study is for
- Stroke
- What is being tested?
- Acupuncture
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- No sites listed yet
- Study dates
- 15 Aug 2025to 15 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- 1. The study involved forty patients male and female aged between 45 and 65 years. 2. A confirmed diagnosis of complex regional pain syndrome through clinical assessment by neurologist using The Budapest criteria for diagnosis of CRPS (Choi et al ., 2013
Who cannot join
- 1. Pre-existing history of hand problems and shoulder dysfunction prior to experiencing a stroke . 2. Those with an overactive sympathetic system from alternative causes eg.congestive heart failure,chronic kidney disease(Reynolds \& Minic, 2023) 8 3. individuals with significant musculoskeletal disorders such as rheumatoid arthritis or metabolic disorders including diabetes 4. Pregnancy
About this study
Complex regional pain syndrome (CRPS) is a condition marked by pain that may occur spontaneously or in response to stimuli, often disproportionate to the initial injury.(Chae, 2010). In post-stroke complex regional pain syndrome, patients often have simultaneous shoulder and wrist pain. Symptoms may include edema, increased warmth in the hand, and limited in upper extremity joints. (Yu, 2009).The significance of post-stroke complex regional pain syndrome (CRPS) lies not only in its profound impact on pain perception but also in its broader effects on patients' quality of life.(de mos et al.,2007) Managing complex regional pain syndrome involves a multidisciplinary approach with key physical therapy elements like elevation, massage, range of motion exercises, strengthening, and sensory re-education.(Sethy et al., 2017). Electrotherapy modalities include transcutaneous electrical nerve stimulation. (Palmer, 2015). This includes heat treatments like ultrasound, hot and cold packs, and fluidotherapy
Read the detailed description
In this sense,acupuncture, presents a viable alternative to opioid analgesics for pain relief, offering effective treatment without the risk of dependency. one specific technique, electroacupuncture (ea), enhances traditional acupuncture by applying a small electric current between pairs of needles. research indicates that ea may alleviate pain by activating various bioactive chemicals, engaging multiple mechanisms at the peripheral, spinal, and supraspinal levels. this makes electroacupuncture a promising option for individuals seeking non-addictive pain management solutions.( zhang r, et al 2014).
- Conditions
- Stroke
- Being tested
- Acupuncture
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AcupunctureOther
Acupuncture
| Study group | Role | What they receive |
|---|---|---|
| intervention | Other | Not described Receives: Other: Acupuncture |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual analogue scale
Visual analogue scale (VAS) is valuable tool for assessing the intensity and frequency of symptoms, particularly pain.
Measured: 5 min
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jul 2025
- Study start15 Aug 2025 (estimated)
- Primary completion15 Aug 2025 (estimated)
- Study completion15 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eyad Mohamed Fathy, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07091708
- Sponsor's protocol ID
- 1534998
- Status last verified
- Jul 2025
- First submitted
- 22 Jul 2025
- Last updated
- 29 Jul 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- EFFECT OF ELECTROACUPUNCTURE ON COMPLEX REGIONAL PAIN SYNDROME IN PATIENTS WITH STROKE: A RANDOMIZED CONTROLLED TRIAL
- ClinicalTrials.gov ID
- NCT07091708
- Acronym / sponsor ID
- 1534998
- Conditions
- Stroke
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 Aug 2025 (estimated)
- Primary completion
- 15 Aug 2025 (estimated)
- Study completion
- 15 Jun 2026 (estimated)
- First posted
- 29 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Complex regional pain syndrome (CRPS) is a condition marked by pain that may occur spontaneously or in response to stimuli, often disproportionate to the initial injury.(Chae, 2010). In post-stroke complex regional pain syndrome, patients often have simultaneous shoulder and wrist pain. Symptoms may include edema, increased warmth in the hand, and limited in upper extremity joints. (Yu, 2009).The significance of post-stroke complex regional pain syndrome (CRPS) lies not only in its profound impact on pain perception but also in its broader effects on patients' quality of life.(de mos et al.,2007) Managing complex regional pain syndrome involves a multidisciplinary approach with key physical therapy elements like elevation, massage, range of motion exercises, strengthening, and sensory re-education.(Sethy et al., 2017). Electrotherapy modalities include transcutaneous electrical nerve stimulation. (Palmer, 2015). This includes heat treatments like ultrasound, hot and cold packs, and fluidotherapy
Detailed description
In this sense,acupuncture, presents a viable alternative to opioid analgesics for pain relief, offering effective treatment without the risk of dependency. one specific technique, electroacupuncture (ea), enhances traditional acupuncture by applying a small electric current between pairs of needles. research indicates that ea may alleviate pain by activating various bioactive chemicals, engaging multiple mechanisms at the peripheral, spinal, and supraspinal levels. this makes electroacupuncture a promising option for individuals seeking non-addictive pain management solutions.( zhang r, et al 2014).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| intervention | Other | Other: Acupuncture |
Who may qualify
- Ages
- 45 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- 1. The study involved forty patients male and female aged between 45 and 65 years. 2. A confirmed diagnosis of complex regional pain syndrome through clinical assessment by neurologist using The Budapest criteria for diagnosis of CRPS (Choi et al ., 2013
Key exclusion criteria (1 listed)
- 1. Pre-existing history of hand problems and shoulder dysfunction prior to experiencing a stroke . 2. Those with an overactive sympathetic system from alternative causes eg.congestive heart failure,chronic kidney disease(Reynolds \& Minic, 2023) 8 3. individuals with significant musculoskeletal disorders such as rheumatoid arthritis or metabolic disorders including diabetes 4. Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AcupunctureAcupuncture | Other | intervention |
Primary outcome
Visual analogue scale
Time frame: 5 min
Visual analogue scale (VAS) is valuable tool for assessing the intensity and frequency of symptoms, particularly pain.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Acupuncture in people with Stroke, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 29 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual analogue scale (time frame: 5 min). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2025.