Plastic Surgery ProceduresNCT07094620
Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes
An observational study of Plastic Surgery Procedures, run by Centre Hospitalier Universitaire de Nice at 1 site in France.
Trial summary
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to social isolation, in addition to requiring numerous surgeries. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Plastic Surgery Procedures
- What is being tested?
- Non-surgical rhinoplasty
- Type of treatment
- Surgery or procedure
- How many people
- 6 participants
- Where
- 1 siteFrance
- Study dates
- 15 Jun 2023to 3 May 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients who had undergone non-surgical rhinoplasty with hyaluronic acid injections following surgery to remove nasal skin cancer and who reported dissatisfaction with aesthetic outcomes
Who may be able to join
- A history of nasal skin carcinoma treated surgically with reconstruction, a minimum of one year since the last oncologic surgery, a patient-expressed desire for aesthetic improvement, and either refusal of further surgery or a context in which surgical revision was uncertain or not recommended
Who cannot join
- Any standard contraindications to hyaluronic acid injections, oncologic surgery performed less than one year prior or with uncertain resection margins, metastatic evolution and cases where surgical correction remained more appropriate and accessible than injection-based management
Trial locations and contacts
1 site in 1 country.
About this study
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to social isolation, in addition to requiring numerous surgeries. In this context, and with the expertise of our department in this field, patients may benefit from touch-ups using hyaluronic acid, which can improve the outcome without the need for major and costly surgery. This product has the advantages of being accessible, easy to use, and has demonstrated long-term safety in the literature.The aim of the study is to evaluate, in this context, the benefit of medical rhinoplasty as perceived by the patients, as well as to measure the objective volumetric gain using 3-D photography. It also seeks to encourage professionals in this type of surgery to assess the results and motivate them to train in these techniques.
- Conditions
- Plastic Surgery Procedures
- Being tested
- Non-surgical rhinoplasty
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Non-surgical rhinoplastyRadiation
Non-surgical rhinoplasty using hyaluronic acid at baseline consultation.
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of FACE-Q questionnaire score
Face-Q is a validated questionnaire evaluating patients PROMs in aesthetic procedures.
Measured: Baseline, One month and at Two months
Secondary outcomes (2)
Standardized and 3-Dimensions photographs
Standardized photographs taken with a camera
Measured: Baseline, One month and at Two months
3-Dimensions photographs
3-Dimensions photographs acquired by using the Vectra System with evaluation of volumetric changes
Measured: Baseline, One month and at Two months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jul 2025
- Study start15 Jun 2023
- Primary completion3 May 2024
- Study completion3 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Plastic Surgery ProceduresStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire de NiceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire de Nice
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07094620
- Sponsor's protocol ID
- 25Rhino01
- Status last verified
- Jul 2025
- First submitted
- 23 Jul 2025
- Last updated
- 30 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes
- ClinicalTrials.gov ID
- NCT07094620
- Acronym / sponsor ID
- 25Rhino01
- Conditions
- Plastic Surgery Procedures
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 6 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire de NiceUniversity, hospital or other
- Study start
- 15 Jun 2023 (actual)
- Primary completion
- 3 May 2024 (actual)
- Study completion
- 3 May 2024 (actual)
- First posted
- 30 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to social isolation, in addition to requiring numerous surgeries. In this context, and with the expertise of our department in this field, patients may benefit from touch-ups using hyaluronic acid, which can improve the outcome without the need for major and costly surgery. This product has the advantages of being accessible, easy to use, and has demonstrated long-term safety in the literature.The aim of the study is to evaluate, in this context, the benefit of medical rhinoplasty as perceived by the patients, as well as to measure the objective volumetric gain using 3-D photography. It also seeks to encourage professionals in this type of surgery to assess the results and motivate them to train in these techniques.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients who had undergone non-surgical rhinoplasty with hyaluronic acid injections following surgery to remove nasal skin cancer and who reported dissatisfaction with aesthetic outcomes
Key inclusion criteria (1 listed)
- A history of nasal skin carcinoma treated surgically with reconstruction, a minimum of one year since the last oncologic surgery, a patient-expressed desire for aesthetic improvement, and either refusal of further surgery or a context in which surgical revision was uncertain or not recommended
Key exclusion criteria (1 listed)
- Any standard contraindications to hyaluronic acid injections, oncologic surgery performed less than one year prior or with uncertain resection margins, metastatic evolution and cases where surgical correction remained more appropriate and accessible than injection-based management
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Non-surgical rhinoplastyNon-surgical rhinoplasty using hyaluronic acid at baseline consultation. | Radiation | – |
Primary outcome
Evaluation of FACE-Q questionnaire score
Time frame: Baseline, One month and at Two months
Face-Q is a validated questionnaire evaluating patients PROMs in aesthetic procedures.
2 secondary outcomes
Standardized and 3-Dimensions photographs
Time frame: Baseline, One month and at Two months
3-Dimensions photographs
Time frame: Baseline, One month and at Two months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Plastic Surgery Procedures, run by Centre Hospitalier Universitaire de Nice at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of FACE-Q questionnaire score (time frame: Baseline, One month and at Two months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jul 2025.