VaccinationConectadosNCT07096245
Conectados: Social Networks and Social Media for Vaccine Uptake
A study testing Vaccine Information Video Dissemination in people with Vaccination, run by University of California, San Francisco at 1 site in United States.
Trial summary
This study is testing different ways of sharing a short, community-informed video about flu and COVID-19 vaccines to see how people respond to it. The video was created with input from Indigenous community members in California and provides information to support vaccine decision-making. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Vaccination
- What is being tested?
- Vaccine Information Video Dissemination
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 507 participants
- Where
- 1 siteUnited States
- Study dates
- 10 Sep 2025to 15 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Age 18 years or older
- Currently resides in California
- Able to access and view an online video
- Able to complete an online survey in English or Spanish For Arm 2 only (Participant Seed Arm): must have participated in the prior Aim 1 survey and consented to recontact
Who cannot join
- Under 18 years of age
- Does not reside in California
- Unable to access the internet to view the intervention video or complete the survey
Trial locations and contacts
1 site in 1 country.
United States1 site
University of California, San Francisco
San Francisco, California, 94158
About this study
This study is testing different ways of sharing a short, community-informed video about flu and COVID-19 vaccines to see how people respond to it. The video was created with input from Indigenous community members in California and provides information to support vaccine decision-making. Participants may see the video in one of three ways: through a paid advertisement on social media, from a trusted community organization, or from someone they know personally. After watching the video, viewers will be asked to answer one question about how much they trust it, and they may choose to complete a short survey about their vaccine views and how they received the video. The goal is to understand how trust in vaccine information changes depending on who shares it, and to improve the way health messages are delivered to Indigenous and other underserved communities.
Read the detailed description
This is a randomized dissemination trial evaluating the impact of different message delivery strategies on trust, attitudes, and behavioral intentions related to flu and COVID-19 vaccination. The intervention consists of a short (approximately 2-minute) culturally tailored video, developed using human-centered design and community-based participatory approaches with Indigenous communities in California.
Participants are exposed to the video through one of three dissemination arms: (1) paid advertisements on Facebook and Instagram targeting adults 65 and older in California; (2) peer-to-peer sharing by "seed" participants recruited from a prior phase of the study; and (3) community-based organization (CBO) outreach using established communication channels. All participants view the same video.
After viewing the video, participants are asked to respond to a single poll item ("How much do you trust this video?") and are invited to complete an optional, anonymous online survey assessing vaccine confidence, trust in the information source, and willingness to share the video. Survey responses are linked to the dissemination arm for comparative analysis.
Seed participants receive personalized, trackable video links and instructions to share them with at least 10 contacts in their network. Click-level analytics (e.g., timestamp, referral source, general location) are collected through Bitly or Rebrandly links. YouTube analytics will also be used to evaluate video engagement (e.g., views, retention, traffic source). No identifiable health information is collected unless participants voluntarily provide contact information to complete the survey by phone.
The primary outcome is the level of trust in the video across dissemination arms. Secondary outcomes include survey completion rate, willingness to share the video, and changes in vaccine-related attitudes. Data will be stratified by dissemination method and, for seed participants, linked to prior social network data collected in Phase 1.
- Conditions
- Vaccination
- Being tested
- Vaccine Information Video Dissemination
- Keywords
- vaccination, social media, intervention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Vaccine Information Video DisseminationBehavioural
The intervention is a brief, community-informed educational video (2-3 minutes) focused on seasonal flu and COVID-19 vaccination. The video was developed using human-centered design and community-based participatory methods with Indigenous community members in California. It aims to promote trust in vaccines by presenting clear, culturally relevant health information.
The video is disseminated using three behavioral delivery strategies: (1) paid advertisements on Facebook and Instagram targeting adults in California, (2) peer-to-peer sharing by participants who previously enrolled in the study and are invited to serve as "seeds" who share the video with their personal contacts, and (3) distribution by trusted community-based organizations (CBOs) using their existing communication networks, including WhatsApp, social media, email, and newsletters. All viewers are prompted to complete a one-question trust poll and invited to participate in an optional anonymous survey on vaccine attitud
| Study group | Role | What they receive |
|---|---|---|
| Social media | Active comparator | Participants in this arm will view a short (2-3 minute) educational video about flu and COVID-19 vaccines through paid advertisements on Facebook and Instagram. After viewing the video, they will be asked to respond to a single poll question: "How much do you trust this video?" Participants will then be invited to complete an optional, anonymous online survey assessing vaccine confidence, trust in the information source, and willingness to share the video. All procedures are self-directed and occur online. Receives: Behavioral: Vaccine Information Video Dissemination |
| Participant seed | Experimental | Participants in this arm are individuals who previously completed a related survey and consented to be recontacted. These "seed" participants receive a personalized video link and instructions to share it with at least 10 people in their personal networks. They will first watch the same 2-3 minute vaccine education video, answer a 1-question poll ("How much do you trust this video?"), and complete an anonymous online survey assessing vaccine attitudes, trust in the message and source, and willingness to share. Recipients of their shared video link may also complete the poll and survey. Sharing patterns are tracked via unique link analytics. Receives: Behavioral: Vaccine Information Video Dissemination |
| Community based organizations | Experimental | Participants in this arm will view a short educational video about flu and COVID-19 vaccines distributed by trusted community-based organizations (CBOs) using their usual communication methods, such as WhatsApp, email, newsletters, or social media. After watching the video, participants will be asked to answer a 1-question poll ("How much do you trust this video?") and will be invited to complete an optional, anonymous online survey assessing vaccine attitudes, trust in the source of the information, and willingness to share the video. CBOs will use unique tracking links to monitor video engagement. Receives: Behavioral: Vaccine Information Video Dissemination |
What is being measured
The primary outcome is the main question the study is designed to answer.
Trust in vaccine video message by dissemination arm
Participants will be asked to answer a single poll question after viewing a 2-3 minute vaccine education video: "How much do you trust this video?" Responses will be collected on a 4-point Likert scale (Not at all, A little, Mostly, Completely). The primary outcome is the level of trust reported, compared across dissemination arms (paid social media ads, peer-to-peer sharing, and community-based organization distribution). Analysis will assess differences in trust levels based on who shared the video.
Measured: immediately after exposure
Intention
Assesses participants' reported likelihood of getting a seasonal flu or COVID-19 vaccine after viewing the intervention video. Measured on a 6-point scale from "Very unlikely" to "Very likely," including an option for participants who have already received the vaccine. Analysis will examine variation by dissemination arm and correlation with trust in the video.
Measured: Immediately after video exposure
Secondary outcomes (2)
Self-reported exposure to new information
Participants are asked whether the video provided them with new information related to flu or COVID-19 vaccines. This binary outcome (Yes/No/Not sure) helps assess the video's educational value.
Measured: Immediately after video exposure
Trust in message source
Assesses how much participants trust the person or group from whom they received the video. Measured on a 4-point scale (Not at all, A little, Mostly, Completely).
Measured: Immediately after video exposure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Jul 2025
- Study start10 Sep 2025
- Primary completion15 Dec 2025
- Study completion15 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for VaccinationStudies of the same condition, open and under way.
- More trials run by University of California, San FranciscoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 507 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of California, San Francisco
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Nadia Diamond-Smith, PhD, MS, Principal investigator, University of California, San Francisco
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07096245
- Sponsor's protocol ID
- 23-38709
- Acronym
- Conectados
- Status last verified
- Mar 2026
- First submitted
- 24 Jul 2025
- Last updated
- 6 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: We plan to share de-identified individual-level survey data collected through the optional online Qualtrics survey, including participants' self-reported trust in the video, vaccine attitudes, exposure history, sharing behavior, and demographics (e.g., age group, gender, Indigenous identification). No names, contact information, or IP addresses will be shared. Data will be available to qualified researchers upon reasonable request and subject to data use agreements that protect participant privacy.
Publications
Abascal Miguel L, Epperson AE, Comfort AB, Leon D, Garcia ME, Riley AR, Diamond-Smith N. Digital Dissemination Strategies for Health Promotion Videos in Indigenous Communities in California: Protocol for a Three-Arm Comparative Study. JMIR Res Protoc. 2026 Mar 17;15:e84674. doi: 10.2196/84674.
PubMed 41843796
Study at a glance
From the registry record, last updated by the sponsor on 6 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Conectados: Social Networks and Social Media for Vaccine Uptake
- ClinicalTrials.gov ID
- NCT07096245
- Acronym / sponsor ID
- Conectados / 23-38709
- Conditions
- Vaccination
- Keywords
- vaccination, social media, intervention
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 507 participants (actual)
- Lead sponsor
- University of California, San FranciscoUniversity, hospital or other
- Study start
- 10 Sep 2025 (actual)
- Primary completion
- 15 Dec 2025 (actual)
- Study completion
- 15 Dec 2025 (actual)
- First posted
- 31 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is testing different ways of sharing a short, community-informed video about flu and COVID-19 vaccines to see how people respond to it. The video was created with input from Indigenous community members in California and provides information to support vaccine decision-making. Participants may see the video in one of three ways: through a paid advertisement on social media, from a trusted community organization, or from someone they know personally. After watching the video, viewers will be asked to answer one question about how much they trust it, and they may choose to complete a short survey about their vaccine views and how they received the video. The goal is to understand how trust in vaccine information changes depending on who shares it, and to improve the way health messages are delivered to Indigenous and other underserved communities.
Detailed description
This is a randomized dissemination trial evaluating the impact of different message delivery strategies on trust, attitudes, and behavioral intentions related to flu and COVID-19 vaccination. The intervention consists of a short (approximately 2-minute) culturally tailored video, developed using human-centered design and community-based participatory approaches with Indigenous communities in California.
Participants are exposed to the video through one of three dissemination arms: (1) paid advertisements on Facebook and Instagram targeting adults 65 and older in California; (2) peer-to-peer sharing by "seed" participants recruited from a prior phase of the study; and (3) community-based organization (CBO) outreach using established communication channels. All participants view the same video.
After viewing the video, participants are asked to respond to a single poll item ("How much do you trust this video?") and are invited to complete an optional, anonymous online survey assessing vaccine confidence, trust in the information source, and willingness to share the video. Survey responses are linked to the dissemination arm for comparative analysis.
Seed participants receive personalized, trackable video links and instructions to share them with at least 10 contacts in their network. Click-level analytics (e.g., timestamp, referral source, general location) are collected through Bitly or Rebrandly links. YouTube analytics will also be used to evaluate video engagement (e.g., views, retention, traffic source). No identifiable health information is collected unless participants voluntarily provide contact information to complete the survey by phone.
The primary outcome is the level of trust in the video across dissemination arms. Secondary outcomes include survey completion rate, willingness to share the video, and changes in vaccine-related attitudes. Data will be stratified by dissemination method and, for seed participants, linked to prior social network data collected in Phase 1.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Social media | Active comparator | Behavioral: Vaccine Information Video DisseminationParticipants in this arm will view a short (2-3 minute) educational video about flu and COVID-19 vaccines through paid advertisements on Facebook and Instagram. After viewing the video, they will be asked to respond to a single poll question: "How much do you trust this video?" Participants will then be invited to complete an optional, anonymous online survey assessing vaccine confidence, trust in the information source, and willingness to share the video. All procedures are self-directed and occur online. |
| Participant seed | Experimental | Behavioral: Vaccine Information Video DisseminationParticipants in this arm are individuals who previously completed a related survey and consented to be recontacted. These "seed" participants receive a personalized video link and instructions to share it with at least 10 people in their personal networks. They will first watch the same 2-3 minute vaccine education video, answer a 1-question poll ("How much do you trust this video?"), and complete an anonymous online survey assessing vaccine attitudes, trust in the message and source, and willingness to share. Recipients of their shared video link may also complete the poll and survey. Sharing patterns are tracked via unique link analytics. |
| Community based organizations | Experimental | Behavioral: Vaccine Information Video DisseminationParticipants in this arm will view a short educational video about flu and COVID-19 vaccines distributed by trusted community-based organizations (CBOs) using their usual communication methods, such as WhatsApp, email, newsletters, or social media. After watching the video, participants will be asked to answer a 1-question poll ("How much do you trust this video?") and will be invited to complete an optional, anonymous online survey assessing vaccine attitudes, trust in the source of the information, and willingness to share the video. CBOs will use unique tracking links to monitor video engagement. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age 18 years or older
- Currently resides in California
- Able to access and view an online video
- Able to complete an online survey in English or Spanish For Arm 2 only (Participant Seed Arm): must have participated in the prior Aim 1 survey and consented to recontact
Key exclusion criteria (3 listed)
- Under 18 years of age
- Does not reside in California
- Unable to access the internet to view the intervention video or complete the survey
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Vaccine Information Video DisseminationThe intervention is a brief, community-informed educational video (2-3 minutes) focused on seasonal flu and COVID-19 vaccination. The video was developed using human-centered design and community-based participatory methods with Indigenous community members in California. It aims to promote trust in vaccines by presenting clear, culturally relevant health information. The video is disseminated using three behavioral delivery strategies: (1) paid advertisements on Facebook and Instagram targeting adults in California, (2) peer-to-peer sharing by participants who previously enrolled in the study and are invited to serve as "seeds" who share the video with their personal contacts, and (3) distribution by trusted community-based organizations (CBOs) using their existing communication networks, including WhatsApp, social media, email, and newsletters. All viewers are prompted to complete a one-question trust poll and invited to participate in an optional anonymous survey on vaccine attitud | Behavioural | Community based organizations, Participant seed, Social media |
Primary outcome
Trust in vaccine video message by dissemination arm
Time frame: immediately after exposure
Participants will be asked to answer a single poll question after viewing a 2-3 minute vaccine education video: "How much do you trust this video?" Responses will be collected on a 4-point Likert scale (Not at all, A little, Mostly, Completely). The primary outcome is the level of trust reported, compared across dissemination arms (paid social media ads, peer-to-peer sharing, and community-based organization distribution). Analysis will assess differences in trust levels based on who shared the video.
Intention
Time frame: Immediately after video exposure
Assesses participants' reported likelihood of getting a seasonal flu or COVID-19 vaccine after viewing the intervention video. Measured on a 6-point scale from "Very unlikely" to "Very likely," including an option for participants who have already received the vaccine. Analysis will examine variation by dissemination arm and correlation with trust in the video.
2 secondary outcomes
Self-reported exposure to new information
Time frame: Immediately after video exposure
Trust in message source
Time frame: Immediately after video exposure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Mar 2026.
- Derived from this study: PubMed 41843796Abascal Miguel L, Epperson AE, Comfort AB, Leon D, Garcia ME, Riley AR, Diamond-Smith N. Digital Dissemination Strategies for Health Promotion Videos in Indigenous Communities in California: Protocol for a Three-Arm Comparative Study. JMIR Res Protoc. 2026 Mar 17;15:e84674. doi: 10.2196/84674.
- Individual participant dataSharing planned: Yes. We plan to share de-identified individual-level survey data collected through the optional online Qualtrics survey, including participants' self-reported trust in the video, vaccine attitudes, exposure history, sharing behavior, and demographics (e.g., age group, gender, Indigenous identification). No names, contact information, or IP addresses will be shared. Data will be available to qualified researchers upon reasonable request and subject to data use agreements that protect participant privacy.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nadia Diamond-Smith, PhD, MS principal investigator
University of California, San Francisco
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Vaccine Information Video Dissemination in people with Vaccination, run by University of California, San Francisco at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Trust in vaccine video message by dissemination arm (time frame: immediately after exposure). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07096245, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Mar 2026; AzTrials last refreshed its copy on 8 Nov 2026.