Cardiac Arrest (CA)NCT07101510
V-CPR Under Special Circumstances
A study testing sV-CPR, V-CPR and T-CPR in people with Cardiac Arrest (CA), run by University of Pecs at 1 site in Hungary.
Trial summary
Out-of-hospital cardiac arrest (OHCA) remains a major cause of death globally, with bystander CPR rates varying widely (13-82%) despite public health efforts. Early recognition, EMS activation, and immediate CPR are key to survival, often beginning with a layperson guided by an emergency dispatcher. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cardiac Arrest (CA)
- What is being tested?
- sV-CPR, V-CPR and T-CPR
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 157 participants
- Where
- 1 siteHungary
- Study dates
- 10 Aug 2025to 10 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- healthy voluntear
Who cannot join
- healthcare professionals (paramedics, nurses, etc.)
- pregnant women
- people with cardio-pulmonary and musculoskeletal diseases or any other impairment that would risk harm for the volunteer while performing CPR for 2 minutes
- physical and/or psychological disabilities
- technical issue during data collection
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of Video-assisted Cardiopulmonary Resuscitation Under Special Circumstances: a Randomized Controlled Simulation Study
Out-of-hospital cardiac arrest (OHCA) remains a major cause of death globally, with bystander CPR rates varying widely (13-82%) despite public health efforts. Early recognition, EMS activation, and immediate CPR are key to survival, often beginning with a layperson guided by an emergency dispatcher.
Telephone-assisted CPR (T-CPR), where dispatchers give verbal instructions, is common but limited-dispatchers can't see the scene or correct CPR technique. In contrast, video-assisted CPR (V-CPR) enables visual feedback, potentially improving performance in areas like compression rate and hand placement. However, evidence is mixed regarding its effect on compression depth, and initiating a video call may introduce delays.
While V-CPR's technical benefits have been studied, little is known about how real-world distractions-like noise or poor lighting-affect its effectiveness. Our simulation study aimed to compare T-CPR and V-CPR under both ideal and challenging conditions to assess the impact of environmental factors on layperson CPR quality and dispatcher support.
Read the detailed description
Out-of-hospital cardiac arrest (OHCA) remains a major global health concern and one of the leading causes of mortality in industrialized nations. Despite various public health initiatives aimed at increasing layperson engagement in early intervention, bystander cardiopulmonary resuscitation (CPR) rates continue to vary widely across countries, ranging from 13% to 82%. Survival after OHCA is strongly associated with the early recognition of cardiac arrest, rapid activation of emergency medical services (EMS), and immediate initiation of effective CPR. In most cases, the first responder is a layperson who contacts the emergency dispatcher-making dispatcher-assisted CPR a critical link in the chain of survival.
Telephone-assisted CPR (T-CPR), where the dispatcher provides audio instructions, is a widely adopted and effective method to initiate life-saving efforts. However, the lack of visual feedback limits its potential: the dispatcher cannot observe the victim's condition, the responder's technique, or the scene dynamics. As a result, certain errors may go uncorrected, and the quality of CPR may be suboptimal.
With advancements in communication technology, real-time video communication between dispatchers and callers has become feasible. Video-assisted CPR (V-CPR) allows dispatchers to visually assess the situation, provide tailored feedback, and correct lay responder errors during the intervention. Several simulation studies have demonstrated that V-CPR can improve CPR performance compared to T-CPR, particularly in terms of compression rate, hand placement, and technique. However, the evidence regarding its superiority in achieving guideline-recommended compression depth remains mixed. Furthermore, the added complexity of initiating a video call and ensuring optimal camera positioning can delay CPR initiation and affect its effectiveness.
While prior studies have explored the technical feasibility and clinical benefits of V-CPR, the influence of environmental and situational variables-such as background noise, poor lighting conditions, or the presence of distractions-remains underexplored. These factors are highly relevant in real-world emergencies and may impact both the lay responder's performance and the dispatcher's ability to guide the process effectively.
Our study aimed to address this gap by conducting a simulation trial to compare the effectiveness of T-CPR and V-CPR under both ideal and environmentally challenging conditions. By systematically examining the impact of common distracting factors, our goal was to better understand the limitations and potential of video-assisted emergency guidance in realistic layperson resuscitation scenarios.
- Conditions
- Cardiac Arrest (CA)
- Being tested
- sV-CPR, V-CPR, T-CPR, sT-CPR
- Keywords
- cardiac arrest, video-assisted CPR, cardiopulmonary resuscitation, V-CPR, special circumstances, dispatcher
- Medical subject headings
- Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
sV-CPRBehavioural
In the sV-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a video connection with a dispatcher located in another room using a smartphone. To simulate challenging conditions, they must carry out the task in near-total darkness, with the phone's flashlight as the only light source.
V-CPRBehavioural
In the V-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a video connection with a dispatcher located in another room using a smartphone.
T-CPRBehavioural
In the T-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a telephone connection with a dispatcher located in another room using a smartphone (vocal communication only).
sT-CPRBehavioural
In the sT-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a telephone connection with a dispatcher located in another room using a smartphone (vocal communication only). To simulate challenging conditions, they must carry out the task in higher environmental noises (traffic), generated by a loudspeaker.
| Study group | Role | What they receive |
|---|---|---|
| sV-CPR | Experimental | Participants perform video-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. Receives: Behavioral: sV-CPR |
| V-CPR | Active comparator | Participants perform video-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. Receives: Behavioral: V-CPR |
| T-CPR | Active comparator | Participants perform telephone-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. Receives: Behavioral: T-CPR |
| sT-CPR | Experimental | Participants perform telephone-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. Receives: Behavioral: sT-CPR |
What is being measured
The primary outcome is the main question the study is designed to answer.
Chest compression depth
Chest compression depth will be evaluated by a manikin connected to a CPR software.
Measured: During procedure.
Secondary outcomes (2)
Chest compression rate
Chest compression rate will be evaluated by a manikin connected to a CPR software.
Measured: During procedure
Hand position during chest compression.
Hand position during chest compression will be evaluated by observation.
Measured: During procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Aug 2025
- Study start10 Aug 2025
- Primary completion10 Sep 2025
- Study completion10 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiac Arrest (CA)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 157 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Pecs
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07101510
- Sponsor's protocol ID
- V-CPR special circumstances
- Status last verified
- Jul 2025
- First submitted
- 28 Jul 2025
- Last updated
- 12 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Video-assisted Cardiopulmonary Resuscitation Under Special Circumstances: a Randomized Controlled Simulation Study
- ClinicalTrials.gov ID
- NCT07101510
- Acronym / sponsor ID
- V-CPR special circumstances
- Conditions
- Cardiac Arrest (CA)
- Keywords
- cardiac arrest, video-assisted CPR, cardiopulmonary resuscitation, V-CPR, special circumstances, dispatcher
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 157 participants (actual)
- Lead sponsor
- University of PecsUniversity, hospital or other
- Study start
- 10 Aug 2025 (actual)
- Primary completion
- 10 Sep 2025 (actual)
- Study completion
- 10 Sep 2025 (actual)
- First posted
- 3 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Out-of-hospital cardiac arrest (OHCA) remains a major cause of death globally, with bystander CPR rates varying widely (13-82%) despite public health efforts. Early recognition, EMS activation, and immediate CPR are key to survival, often beginning with a layperson guided by an emergency dispatcher.
Telephone-assisted CPR (T-CPR), where dispatchers give verbal instructions, is common but limited-dispatchers can't see the scene or correct CPR technique. In contrast, video-assisted CPR (V-CPR) enables visual feedback, potentially improving performance in areas like compression rate and hand placement. However, evidence is mixed regarding its effect on compression depth, and initiating a video call may introduce delays.
While V-CPR's technical benefits have been studied, little is known about how real-world distractions-like noise or poor lighting-affect its effectiveness. Our simulation study aimed to compare T-CPR and V-CPR under both ideal and challenging conditions to assess the impact of environmental factors on layperson CPR quality and dispatcher support.
Detailed description
Out-of-hospital cardiac arrest (OHCA) remains a major global health concern and one of the leading causes of mortality in industrialized nations. Despite various public health initiatives aimed at increasing layperson engagement in early intervention, bystander cardiopulmonary resuscitation (CPR) rates continue to vary widely across countries, ranging from 13% to 82%. Survival after OHCA is strongly associated with the early recognition of cardiac arrest, rapid activation of emergency medical services (EMS), and immediate initiation of effective CPR. In most cases, the first responder is a layperson who contacts the emergency dispatcher-making dispatcher-assisted CPR a critical link in the chain of survival.
Telephone-assisted CPR (T-CPR), where the dispatcher provides audio instructions, is a widely adopted and effective method to initiate life-saving efforts. However, the lack of visual feedback limits its potential: the dispatcher cannot observe the victim's condition, the responder's technique, or the scene dynamics. As a result, certain errors may go uncorrected, and the quality of CPR may be suboptimal.
With advancements in communication technology, real-time video communication between dispatchers and callers has become feasible. Video-assisted CPR (V-CPR) allows dispatchers to visually assess the situation, provide tailored feedback, and correct lay responder errors during the intervention. Several simulation studies have demonstrated that V-CPR can improve CPR performance compared to T-CPR, particularly in terms of compression rate, hand placement, and technique. However, the evidence regarding its superiority in achieving guideline-recommended compression depth remains mixed. Furthermore, the added complexity of initiating a video call and ensuring optimal camera positioning can delay CPR initiation and affect its effectiveness.
While prior studies have explored the technical feasibility and clinical benefits of V-CPR, the influence of environmental and situational variables-such as background noise, poor lighting conditions, or the presence of distractions-remains underexplored. These factors are highly relevant in real-world emergencies and may impact both the lay responder's performance and the dispatcher's ability to guide the process effectively.
Our study aimed to address this gap by conducting a simulation trial to compare the effectiveness of T-CPR and V-CPR under both ideal and environmentally challenging conditions. By systematically examining the impact of common distracting factors, our goal was to better understand the limitations and potential of video-assisted emergency guidance in realistic layperson resuscitation scenarios.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| sV-CPR | Experimental | Behavioral: sV-CPRParticipants perform video-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. |
| V-CPR | Active comparator | Behavioral: V-CPRParticipants perform video-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. |
| T-CPR | Active comparator | Behavioral: T-CPRParticipants perform telephone-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. |
| sT-CPR | Experimental | Behavioral: sT-CPRParticipants perform telephone-assisted CPR based on the European Resuscitation Council (ERC) 2021 guidelines. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- healthy voluntear
Key exclusion criteria (5 listed)
- healthcare professionals (paramedics, nurses, etc.)
- pregnant women
- people with cardio-pulmonary and musculoskeletal diseases or any other impairment that would risk harm for the volunteer while performing CPR for 2 minutes
- physical and/or psychological disabilities
- technical issue during data collection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| sV-CPRIn the sV-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a video connection with a dispatcher located in another room using a smartphone. To simulate challenging conditions, they must carry out the task in near-total darkness, with the phone's flashlight as the only light source. | Behavioural | sV-CPR |
| V-CPRIn the V-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a video connection with a dispatcher located in another room using a smartphone. | Behavioural | V-CPR |
| T-CPRIn the T-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a telephone connection with a dispatcher located in another room using a smartphone (vocal communication only). | Behavioural | T-CPR |
| sT-CPRIn the sT-CPR group, participants manage a simulated cardiac arrest scenario alone. They perform CPR while establishing a telephone connection with a dispatcher located in another room using a smartphone (vocal communication only). To simulate challenging conditions, they must carry out the task in higher environmental noises (traffic), generated by a loudspeaker. | Behavioural | sT-CPR |
Primary outcome
Chest compression depth
Time frame: During procedure.
Chest compression depth will be evaluated by a manikin connected to a CPR software.
2 secondary outcomes
Chest compression rate
Time frame: During procedure
Hand position during chest compression.
Time frame: During procedure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing sV-CPR, V-CPR and T-CPR in people with Cardiac Arrest (CA), run by University of Pecs at 1 site in Hungary.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Hungary. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Chest compression depth (time frame: During procedure.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Sep 2025.