10-20 mm Pedunculated Colorectal PolypNCT07114380
Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp
A study testing Cold snare polypectomy in people with 10-20 mm Pedunculated Colorectal Polyp, run by National Taiwan University Hospital at 5 sites in Taiwan.
Trial summary
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm pedunculated colorectal polyps. The main questions it aims to answer are: 1. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- 10-20 mm Pedunculated Colorectal Polyp
- What is being tested?
- Cold snare polypectomy
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 5 sitesTaiwan
- Study dates
- 25 Aug 2025to Apr 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥ 20 years
- Undergoing colonoscopy for any clinical indication
- Found to have a 10-20 mm pedunculated colorectal polyp suitable for cold snare polypectomy
Who cannot join
- Age < 20 years
- Medical contraindications to colonoscopy or polypectomy (e.g., recent myocardial infarction, stroke, severe unstable cardiovascular disease, acute peritonitis, fulminant colitis, perforation, or toxic megacolon)
- Inadequate bowel preparation preventing complete colonoscopy or safe polypectomy
Trial locations and contacts
5 sites in 1 country. Contact the study team or a site near you to ask about taking part.
5 sites in 1 country
Taiwan5 sites, 5 recruiting
- Recruiting
National Taiwan University Hospital Hsin-Chu Branch
Hsinchu
Hsuan-Ho Lin, +886972654359, to-start@hotmail.com
- Recruiting
National Taiwan University Hospital, Jinshan Branch
New Taipei City, 20844
Hsin-Yun Wu, +886972655958, kimwu010063@gmail.com
- Recruiting
National Taiwan University Cancer Center
Taipei
Hao-Che Chang, +886972653109, werdnaryu@livemail.tw
- Recruiting
National Taiwan University Hospital, Bei-Hu Branch
Taipei
Sheng-Jie Chang, +886972653951, b101097070@tmu.edu.tw
- Recruiting
National Taiwan University Hospital
Taipei
Li-Chun Chang, +886972651258, lichunchang@ntu.edu.tw
About this study
Official title: Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp: One Feasibility and Safety Study
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm pedunculated colorectal polyps.
The main questions it aims to answer are:
- Can cold snare polypectomy achieve complete removal of 10-20 mm pedunculated polyps?
- What are the rates and types of complications associated with this technique?
Participants will:
- Undergo colonoscopy as clinically indicated
- Have 10-20 mm pedunculated polyps removed using cold snare polypectomy if eligible
- Be monitored for post-procedure outcomes, including pathology results and any complications
Read the detailed description
This is a prospective, multicenter, single-arm clinical trial designed to evaluate the feasibility and safety of cold snare polypectomy (CSP) for the removal of 10-20 mm pedunculated (0-Ip) colorectal polyps. While CSP is widely recommended for polyps <10 mm due to its favorable safety profile and comparable efficacy to hot snare polypectomy (HSP), its application for larger pedunculated polyps remains insufficiently studied, particularly given concerns regarding bleeding risk.
The study will enroll 120 adult participants undergoing colonoscopy at one of five hospitals in Taiwan. Participants found to have 10-20 mm 0-Ip polyps that are deemed amenable to CSP will undergo cold snare resection by experienced endoscopists. Standard pre- and post-procedure care will be followed. Polyp characteristics, resection outcomes, and complications (e.g., immediate or delayed bleeding, perforation, emergency visits) will be recorded.
Primary endpoints include technical success (complete removal as assessed by endoscopy and pathology) and safety (rate of adverse events such as bleeding or perforation). Clinical and procedural data will be collected prospectively, and statistical analysis will be conducted to identify predictors of CSP failure using univariate and multivariate models.
This study aims to fill a critical knowledge gap in the literature regarding the appropriateness of CSP for larger pedunculated lesions and inform future guideline recommendations.
- Conditions
- 10-20 mm Pedunculated Colorectal Polyp
- Being tested
- Cold snare polypectomy
- Keywords
- cold snare polypectomy, pedunculated polyp, efficacy, safety
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cold snare polypectomyDevice
Unlike traditional hot snare polypectomy or endoscopic mucosal resection, which use electrocautery to resect larger or pedunculated polyps, cold snare polypectomy uses mechanical transection alone without cautery. The procedure is performed using a dedicated cold snare by experienced endoscopists.
| Study group | Role | What they receive |
|---|---|---|
| Cold snare polypectomy | Experimental | Participants in this single-arm study will undergo cold snare polypectomy (CSP) for removal of 10-20 mm pedunculated colorectal polyps identified during clinically indicated colonoscopy. CSP will be performed using standard cold snares without electrocautery. The procedure will be conducted by experienced endoscopists, and all peri-procedural care will follow routine clinical protocols. Outcomes will include complete resection rate, procedure time, and occurrence of adverse events such as immediate or delayed bleeding, perforation, and emergency visits. Receives: Device: Cold snare polypectomy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cold snare polypectomy successful resection rate
The investigators will record whether each polyp is removed by cold snare polypectomy with or without resistance. These will be considered successful resection cases. Polyps that cannot be removed by cold snare polypectomy and require switching to hot snare polypectomy will be considered failed resection cases.
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour)
Secondary outcomes (11)
Number of Polyps with Immediate Bleeding After Cold Snare Polypectomy
Definition: Immediate bleeding would be assessed and graded during the procedure. The severity grades were listed as followed,
- Grade 1: Spontaneous hemostasis within 1 minute
- Grade 2: Continuous but decreased oozing over 1 minute
- Grade 3: Continuous oozing over 1 minute
- Grade 4: Active spurting
Unit of Measure: Number of polyps with immediate bleeding, stratified by grade
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Participants with Delayed Bleeding After Cold Snare Polypectomy
Definition: Any bleeding episode occurring after the patient has left the endoscopy unit and within 14 days post-polypectomy, classified as:
Mild: Bleeding stops spontaneously without medical intervention
Severe: Hemoglobin drop >2 g/dL from baseline, need for blood transfusion, or requirement of endoscopic, angiographic, or surgical hemostasis
Unit of Measure: Number of participants with delayed bleeding
Measured: From completion of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Number of Participants with Perforation
Definition: Any full-thickness defect of the colonic wall identified during or after the procedure.
Unit of Measure: Number of participants with perforation
Measured: From start of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Number of Participants with Post-Polypectomy Emergency Department Visits
Definition: Any unplanned emergency department visit related to post-polypectomy complications.
Unit of Measure: Number of participants with emergency department visits
Measured: From start of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Polypectomy time
Description: Time from when the snaring instrument first appears on the colonoscopy screen to when colonoscope withdrawal resumes after polypectomy.
Unit of Measure: Seconds
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Withdrawal Time
Description: Total time taken to withdraw the colonoscope from cecum to anus
Unit of Measure: Minutes
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps with En Bloc Resection
Description: Whether the polyp was removed in a single piece (en bloc).
Unit of Measure: Number of polyps with en bloc resection
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps with Complete Histologic Resection
Description: Whether pathology confirms tumor-free margins in the resected specimen.
Unit of Measure: Number of polyps with complete histologic resection
Measured: From end of colonoscopy exam to pathology report, usually within 2 weeks.
Number of Polyps Requiring Prophylactic Hemoclipping
Description: Whether hemoclips were applied prophylactically after cold snare polypectomy.
Unit of Measure: Number of polyps requiring prophylactic hemoclipping
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps Requiring Submucosal Injection
Description: Whether submucosal injection was required before or during cold snare polypectomy.
Unit of Measure: Number of polyps requiring submucosal injection
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps Successfully Retrieved
Description: The number of resected polyps that are successfully retrieved and submitted for histologic evaluation.
Unit of Measure: Number of polyps successfully retrieved
Measured: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Aug 2025
- Study start25 Aug 2025
- Primary completionMar 2028 (estimated)
- Study completionApr 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for 10-20 mm Pedunculated Colorectal PolypStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Li-Chun Chang, MD, PhD, Principal investigator, National Taiwan University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07114380
- Sponsor's protocol ID
- 202505029RINA
- Status last verified
- Jul 2025
- First submitted
- 20 Jul 2025
- Last updated
- 19 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No
Publications
Tseng CH, Chang LC, Wu JL, Chang CY, Chen CY, Chen PJ, Shun CT, Hsu WF, Chen YN, Chen CC, Huang TY, Tu CH, Chen MJ, Chou CK, Lee CT, Chen PY, Lin JT, Wu MS, Chiu HM. Bleeding Risk of Cold Versus Hot Snare Polypectomy for Pedunculated Colorectal Polyps Measuring 10 mm or Less: Subgroup Analysis of a Large Randomized Controlled Trial. Am J Gastroenterol. 2024 Nov 1;119(11):2233-2240. doi: 10.14309/ajg.0000000000002847. Epub 2024 May 9.
PubMed 38775310Ferlitsch M, Hassan C, Bisschops R, Bhandari P, Dinis-Ribeiro M, Risio M, Paspatis GA, Moss A, Libanio D, Lorenzo-Zuniga V, Voiosu AM, Rutter MD, Pellise M, Moons LMG, Probst A, Awadie H, Amato A, Takeuchi Y, Repici A, Rahmi G, Koecklin HU, Albeniz E, Rockenbauer LM, Waldmann E, Messmann H, Triantafyllou K, Jover R, Gralnek IM, Dekker E, Bourke MJ. Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2024. Endoscopy. 2024 Jul;56(7):516-545. doi: 10.1055/a-2304-3219. Epub 2024 Apr 26.
PubMed 38670139Kaltenbach T, Anderson JC, Burke CA, Dominitz JA, Gupta S, Lieberman D, Robertson DJ, Shaukat A, Syngal S, Rex DK. Endoscopic Removal of Colorectal Lesions-Recommendations by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2020 Mar;158(4):1095-1129. doi: 10.1053/j.gastro.2019.12.018. Epub 2020 Feb 11. No abstract available.
PubMed 32122632Copland AP, Kahi CJ, Ko CW, Ginsberg GG. AGA Clinical Practice Update on Appropriate and Tailored Polypectomy: Expert Review. Clin Gastroenterol Hepatol. 2024 Mar;22(3):470-479.e5. doi: 10.1016/j.cgh.2023.10.012. Epub 2023 Nov 28.
PubMed 38032585Qu J, Jian H, Li L, Zhang Y, Feng B, Li Z, Zuo X. Effectiveness and safety of cold versus hot snare polypectomy: A meta-analysis. J Gastroenterol Hepatol. 2019 Jan;34(1):49-58. doi: 10.1111/jgh.14464. Epub 2018 Sep 26.
PubMed 30176072Chang LC, Chang CY, Chen CY, Tseng CH, Chen PJ, Shun CT, Hsu WF, Chen YN, Chen CC, Huang TY, Tu CH, Chen MJ, Chou CK, Lee CT, Chen PY, Wu MS, Chiu HM. Cold Versus Hot Snare Polypectomy for Small Colorectal Polyps : A Pragmatic Randomized Controlled Trial. Ann Intern Med. 2023 Mar;176(3):311-319. doi: 10.7326/M22-2189. Epub 2023 Feb 21.
PubMed 36802753
Study at a glance
From the registry record, last updated by the sponsor on 19 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp: One Feasibility and Safety Study
- ClinicalTrials.gov ID
- NCT07114380
- Acronym / sponsor ID
- 202505029RINA
- Conditions
- 10-20 mm Pedunculated Colorectal Polyp
- Keywords
- cold snare polypectomy, pedunculated polyp, efficacy, safety
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 25 Aug 2025 (actual)
- Primary completion
- Mar 2028 (estimated)
- Study completion
- Apr 2028 (estimated)
- First posted
- 11 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm pedunculated colorectal polyps.
The main questions it aims to answer are:
- Can cold snare polypectomy achieve complete removal of 10-20 mm pedunculated polyps?
- What are the rates and types of complications associated with this technique?
Participants will:
- Undergo colonoscopy as clinically indicated
- Have 10-20 mm pedunculated polyps removed using cold snare polypectomy if eligible
- Be monitored for post-procedure outcomes, including pathology results and any complications
Detailed description
This is a prospective, multicenter, single-arm clinical trial designed to evaluate the feasibility and safety of cold snare polypectomy (CSP) for the removal of 10-20 mm pedunculated (0-Ip) colorectal polyps. While CSP is widely recommended for polyps <10 mm due to its favorable safety profile and comparable efficacy to hot snare polypectomy (HSP), its application for larger pedunculated polyps remains insufficiently studied, particularly given concerns regarding bleeding risk.
The study will enroll 120 adult participants undergoing colonoscopy at one of five hospitals in Taiwan. Participants found to have 10-20 mm 0-Ip polyps that are deemed amenable to CSP will undergo cold snare resection by experienced endoscopists. Standard pre- and post-procedure care will be followed. Polyp characteristics, resection outcomes, and complications (e.g., immediate or delayed bleeding, perforation, emergency visits) will be recorded.
Primary endpoints include technical success (complete removal as assessed by endoscopy and pathology) and safety (rate of adverse events such as bleeding or perforation). Clinical and procedural data will be collected prospectively, and statistical analysis will be conducted to identify predictors of CSP failure using univariate and multivariate models.
This study aims to fill a critical knowledge gap in the literature regarding the appropriateness of CSP for larger pedunculated lesions and inform future guideline recommendations.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Cold snare polypectomy | Experimental | Device: Cold snare polypectomyParticipants in this single-arm study will undergo cold snare polypectomy (CSP) for removal of 10-20 mm pedunculated colorectal polyps identified during clinically indicated colonoscopy. CSP will be performed using standard cold snares without electrocautery. The procedure will be conducted by experienced endoscopists, and all peri-procedural care will follow routine clinical protocols. Outcomes will include complete resection rate, procedure time, and occurrence of adverse events such as immediate or delayed bleeding, perforation, and emergency visits. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age ≥ 20 years
- Undergoing colonoscopy for any clinical indication
- Found to have a 10-20 mm pedunculated colorectal polyp suitable for cold snare polypectomy
Key exclusion criteria (3 listed)
- Age < 20 years
- Medical contraindications to colonoscopy or polypectomy (e.g., recent myocardial infarction, stroke, severe unstable cardiovascular disease, acute peritonitis, fulminant colitis, perforation, or toxic megacolon)
- Inadequate bowel preparation preventing complete colonoscopy or safe polypectomy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cold snare polypectomyUnlike traditional hot snare polypectomy or endoscopic mucosal resection, which use electrocautery to resect larger or pedunculated polyps, cold snare polypectomy uses mechanical transection alone without cautery. The procedure is performed using a dedicated cold snare by experienced endoscopists. | Device | Cold snare polypectomy |
Primary outcome
Cold snare polypectomy successful resection rate
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour)
The investigators will record whether each polyp is removed by cold snare polypectomy with or without resistance. These will be considered successful resection cases. Polyps that cannot be removed by cold snare polypectomy and require switching to hot snare polypectomy will be considered failed resection cases.
11 secondary outcomes
Number of Polyps with Immediate Bleeding After Cold Snare Polypectomy
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Participants with Delayed Bleeding After Cold Snare Polypectomy
Time frame: From completion of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Number of Participants with Perforation
Time frame: From start of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Number of Participants with Post-Polypectomy Emergency Department Visits
Time frame: From start of colonoscopy until the date of first documented event, assessed up to 14 days post-procedure.
Polypectomy time
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Withdrawal Time
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps with En Bloc Resection
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps with Complete Histologic Resection
Time frame: From end of colonoscopy exam to pathology report, usually within 2 weeks.
Number of Polyps Requiring Prophylactic Hemoclipping
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps Requiring Submucosal Injection
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Number of Polyps Successfully Retrieved
Time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Sep 2025.
- Background: PubMed 38775310Tseng CH, Chang LC, Wu JL, Chang CY, Chen CY, Chen PJ, Shun CT, Hsu WF, Chen YN, Chen CC, Huang TY, Tu CH, Chen MJ, Chou CK, Lee CT, Chen PY, Lin JT, Wu MS, Chiu HM. Bleeding Risk of Cold Versus Hot Snare Polypectomy for Pedunculated Colorectal Polyps Measuring 10 mm or Less: Subgroup Analysis of a Large Randomized Controlled Trial. Am J Gastroenterol. 2024 Nov 1;119(11):2233-2240. doi: 10.14309/ajg.0000000000002847. Epub 2024 May 9.
- Background: PubMed 38670139Ferlitsch M, Hassan C, Bisschops R, Bhandari P, Dinis-Ribeiro M, Risio M, Paspatis GA, Moss A, Libanio D, Lorenzo-Zuniga V, Voiosu AM, Rutter MD, Pellise M, Moons LMG, Probst A, Awadie H, Amato A, Takeuchi Y, Repici A, Rahmi G, Koecklin HU, Albeniz E, Rockenbauer LM, Waldmann E, Messmann H, Triantafyllou K, Jover R, Gralnek IM, Dekker E, Bourke MJ. Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2024. Endoscopy. 2024 Jul;56(7):516-545. doi: 10.1055/a-2304-3219. Epub 2024 Apr 26.
- Background: PubMed 32122632Kaltenbach T, Anderson JC, Burke CA, Dominitz JA, Gupta S, Lieberman D, Robertson DJ, Shaukat A, Syngal S, Rex DK. Endoscopic Removal of Colorectal Lesions-Recommendations by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2020 Mar;158(4):1095-1129. doi: 10.1053/j.gastro.2019.12.018. Epub 2020 Feb 11. No abstract available.
- Background: PubMed 38032585Copland AP, Kahi CJ, Ko CW, Ginsberg GG. AGA Clinical Practice Update on Appropriate and Tailored Polypectomy: Expert Review. Clin Gastroenterol Hepatol. 2024 Mar;22(3):470-479.e5. doi: 10.1016/j.cgh.2023.10.012. Epub 2023 Nov 28.
- Background: PubMed 30176072Qu J, Jian H, Li L, Zhang Y, Feng B, Li Z, Zuo X. Effectiveness and safety of cold versus hot snare polypectomy: A meta-analysis. J Gastroenterol Hepatol. 2019 Jan;34(1):49-58. doi: 10.1111/jgh.14464. Epub 2018 Sep 26.
- Background: PubMed 36802753Chang LC, Chang CY, Chen CY, Tseng CH, Chen PJ, Shun CT, Hsu WF, Chen YN, Chen CC, Huang TY, Tu CH, Chen MJ, Chou CK, Lee CT, Chen PY, Wu MS, Chiu HM. Cold Versus Hot Snare Polypectomy for Small Colorectal Polyps : A Pragmatic Randomized Controlled Trial. Ann Intern Med. 2023 Mar;176(3):311-319. doi: 10.7326/M22-2189. Epub 2023 Feb 21.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Li-Chun Chang, MD, PhD principal investigator
National Taiwan University Hospital
5 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cold snare polypectomy in people with 10-20 mm Pedunculated Colorectal Polyp, run by National Taiwan University Hospital at 5 sites in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 5 sites in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hsin-Yun Wu, MD (+886978232595, kimwu010063@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cold snare polypectomy successful resection rate (time frame: From the start of the colonoscopy to completion of the procedure, typically within 1 hour)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07114380, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Sep 2025.