StrokeNCT07114575
Gait Characteristics at Different Speeds in Individuals With Stroke
An observational study of Stroke, run by Ankara Yildirim Beyazıt University at 1 site in Turkey (Türkiye).
Trial summary
Stroke is the second leading cause of death and the third leading cause of death combined with disability worldwide. Despite improved recognition and management of stroke risk factors, the risk of stroke has increased by 50% in the last two decades due to increased life expectancy, currently affecting one in every… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke
- What is being tested?
- Gait Analysis
- How many people
- 15 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Aug 2025to 10 Mar 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Stroke survivors.
Who may be able to join
- Having an ICD-10 diagnosis code of G.81 Hemiplegia
- Ability to walk with or without assistance (Functional Ambulation Classification score of 2 or higher)
Who cannot join
- Presence of any known additional neurological or orthopedic condition that may affect walking
- Inability to complete the tests due to cognitive and/or physical reasons
- Inability to complete the analysis at walking speeds increased or decreased by 25%
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Ankara Bilkent City Hospital
Ankara, None Selected, 06800
About this study
Official title: Spatiotemporal Characteristics of Gait at Different Walking Speeds in Individuals With Stroke
Stroke is the second leading cause of death and the third leading cause of death combined with disability worldwide. Despite improved recognition and management of stroke risk factors, the risk of stroke has increased by 50% in the last two decades due to increased life expectancy, currently affecting one in every four individuals. If this trend continues, by 2030, it is estimated that 12 million people will die from stroke, and 70 million will live with its consequences.
Stroke leads to significant changes in the spatiotemporal parameters of gait. Spatial parameters include step length, stride length, and step width, while temporal parameters comprise cadence, stance phase, double support phase (DSP), and swing phase. Gait speed, incorporating both spatial and temporal elements, is classified as a spatiotemporal parameter. Compared to healthy individuals, people post-stroke tend to have increased DSP and stance phases, shortened step lengths, and widened step widths. Asymmetries between the paretic and non-paretic limbs further disrupt gait symmetry.
Previous studies have shown that during prolonged walking tasks such as the 6-minute walk test, both gait speed and symmetry deteriorate in the later stages, potentially due to fatigue. However, changes in walking speed itself may also influence gait symmetry. From this perspective, the aim of this study is to investigate how spatiotemporal gait parameters vary across different walking speeds in individuals with stroke.
Read the detailed description
Stroke is one of the leading causes of death and disability worldwide, with increasing prevalence due to longer life expectancy, despite improved recognition and management of risk factors. Stroke-related impairments, particularly in gait, significantly affect individuals' independence and quality of life. Post-stroke gait is commonly characterized by altered spatiotemporal parameters, including reduced step length, increased double support phase, asymmetry between paretic and non-paretic limbs, and reduced walking speed.
This descriptive study aims to investigate how different walking speeds affect the spatiotemporal gait parameters in individuals with stroke. Specifically, the study will examine walking at comfortable, slow (-25%), and fast (+25%) speeds using an instrumented treadmill (C-Mill). The target population includes adult individuals (18+) diagnosed with hemiplegia (ICD-10: G81), who are able to ambulate with or without assistance (Functional Ambulation Classification ≥2).
Spatiotemporal gait parameters, including step length, step width, cadence, stance and swing phases, and double support time, will be collected for both paretic and non-paretic limbs. These parameters will be assessed at three different walking speeds. In addition to gait analysis, functional status will be evaluated using the Functional Ambulation Classification (FAC), Berg Balance Scale (BBS), and the lower extremity section of the Fugl-Meyer Assessment (FMA-LE). Demographic and clinical information will also be recorded.
Participants will first walk at their comfortable speed to familiarize themselves with the treadmill and to determine baseline parameters. After a 2-minute warm-up walk, a 2-minute data collection phase will follow. The same procedure will be repeated at the slow and fast walking speeds. Gait symmetry and changes in temporal-spatial parameters across walking speeds will be analyzed to explore the influence of speed variation, particularly regarding the mechanisms underlying gait asymmetry and fatigue.
This research will provide insight into how walking speed modulates gait parameters in stroke survivors and may contribute to developing more targeted gait training strategies in neurorehabilitation.
- Conditions
- Stroke
- Being tested
- Gait Analysis
- Keywords
- stroke, spatial, temporal, walking, analysis
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gait AnalysisOther
All participants will undergo gait analysis at three different walking speeds.
| Study group | Role | What they receive |
|---|---|---|
| Self Selected Speed | Participants in this group will perform the gait analysis at their preferred comfortable walking speed. Receives: Other: Gait Analysis | |
| Slow Walking Speed | Participants in this group will walk at a speed approximately 25% slower than their comfortable walking speed. Receives: Other: Gait Analysis | |
| Fast Walking Speed | Participants in this group will walk at a speed approximately 25% faster than their comfortable walking speed. Receives: Other: Gait Analysis |
What is being measured
The primary outcome is the main question the study is designed to answer.
Stance Phase
Stance phase of hemiplegic side during walking. This outcome will be obtained as a result of the gait analysis
Measured: Baseline
Hemiplegic Side Step Length
Step legth of hemiplegic side during walking. This outcome will be obtained as a result of the gait analysis
Measured: Baseline
Double Support Phase
Double support phase during walking. This outcome will be obtained as a result of the gait analysis
Measured: Baseline
Secondary outcomes (1)
Stride Length
Stride length during walking. This outcome will be obtained as a result of the gait analysis.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Aug 2025
- Study start1 Aug 2025
- Primary completion27 Feb 2026
- Study completion10 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Ankara Yildirim Beyazıt UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 15 participants (actual)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Ankara Yildirim Beyazıt University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Murat Akıncı, Ankara Yildirim Beyazıt University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07114575
- Sponsor's protocol ID
- VR01
- Status last verified
- Mar 2026
- First submitted
- 3 Aug 2025
- Last updated
- 12 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Spatiotemporal Characteristics of Gait at Different Walking Speeds in Individuals With Stroke
- ClinicalTrials.gov ID
- NCT07114575
- Acronym / sponsor ID
- VR01
- Conditions
- Stroke
- Keywords
- stroke, spatial, temporal, walking, analysis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 15 participants (actual)
- Lead sponsor
- Ankara Yildirim Beyazıt UniversityUniversity, hospital or other
- Study start
- 1 Aug 2025 (actual)
- Primary completion
- 27 Feb 2026 (actual)
- Study completion
- 10 Mar 2026 (actual)
- First posted
- 11 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Stroke is the second leading cause of death and the third leading cause of death combined with disability worldwide. Despite improved recognition and management of stroke risk factors, the risk of stroke has increased by 50% in the last two decades due to increased life expectancy, currently affecting one in every four individuals. If this trend continues, by 2030, it is estimated that 12 million people will die from stroke, and 70 million will live with its consequences.
Stroke leads to significant changes in the spatiotemporal parameters of gait. Spatial parameters include step length, stride length, and step width, while temporal parameters comprise cadence, stance phase, double support phase (DSP), and swing phase. Gait speed, incorporating both spatial and temporal elements, is classified as a spatiotemporal parameter. Compared to healthy individuals, people post-stroke tend to have increased DSP and stance phases, shortened step lengths, and widened step widths. Asymmetries between the paretic and non-paretic limbs further disrupt gait symmetry.
Previous studies have shown that during prolonged walking tasks such as the 6-minute walk test, both gait speed and symmetry deteriorate in the later stages, potentially due to fatigue. However, changes in walking speed itself may also influence gait symmetry. From this perspective, the aim of this study is to investigate how spatiotemporal gait parameters vary across different walking speeds in individuals with stroke.
Detailed description
Stroke is one of the leading causes of death and disability worldwide, with increasing prevalence due to longer life expectancy, despite improved recognition and management of risk factors. Stroke-related impairments, particularly in gait, significantly affect individuals' independence and quality of life. Post-stroke gait is commonly characterized by altered spatiotemporal parameters, including reduced step length, increased double support phase, asymmetry between paretic and non-paretic limbs, and reduced walking speed.
This descriptive study aims to investigate how different walking speeds affect the spatiotemporal gait parameters in individuals with stroke. Specifically, the study will examine walking at comfortable, slow (-25%), and fast (+25%) speeds using an instrumented treadmill (C-Mill). The target population includes adult individuals (18+) diagnosed with hemiplegia (ICD-10: G81), who are able to ambulate with or without assistance (Functional Ambulation Classification ≥2).
Spatiotemporal gait parameters, including step length, step width, cadence, stance and swing phases, and double support time, will be collected for both paretic and non-paretic limbs. These parameters will be assessed at three different walking speeds. In addition to gait analysis, functional status will be evaluated using the Functional Ambulation Classification (FAC), Berg Balance Scale (BBS), and the lower extremity section of the Fugl-Meyer Assessment (FMA-LE). Demographic and clinical information will also be recorded.
Participants will first walk at their comfortable speed to familiarize themselves with the treadmill and to determine baseline parameters. After a 2-minute warm-up walk, a 2-minute data collection phase will follow. The same procedure will be repeated at the slow and fast walking speeds. Gait symmetry and changes in temporal-spatial parameters across walking speeds will be analyzed to explore the influence of speed variation, particularly regarding the mechanisms underlying gait asymmetry and fatigue.
This research will provide insight into how walking speed modulates gait parameters in stroke survivors and may contribute to developing more targeted gait training strategies in neurorehabilitation.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Day
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Self Selected Speed | – | Other: Gait AnalysisParticipants in this group will perform the gait analysis at their preferred comfortable walking speed. |
| Slow Walking Speed | – | Other: Gait AnalysisParticipants in this group will walk at a speed approximately 25% slower than their comfortable walking speed. |
| Fast Walking Speed | – | Other: Gait AnalysisParticipants in this group will walk at a speed approximately 25% faster than their comfortable walking speed. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Stroke survivors.
Key inclusion criteria (2 listed)
- Having an ICD-10 diagnosis code of G.81 Hemiplegia
- Ability to walk with or without assistance (Functional Ambulation Classification score of 2 or higher)
Key exclusion criteria (3 listed)
- Presence of any known additional neurological or orthopedic condition that may affect walking
- Inability to complete the tests due to cognitive and/or physical reasons
- Inability to complete the analysis at walking speeds increased or decreased by 25%
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gait AnalysisAll participants will undergo gait analysis at three different walking speeds. | Other | Fast Walking Speed, Self Selected Speed, Slow Walking Speed |
Primary outcome
Stance Phase
Time frame: Baseline
Stance phase of hemiplegic side during walking. This outcome will be obtained as a result of the gait analysis
Hemiplegic Side Step Length
Time frame: Baseline
Step legth of hemiplegic side during walking. This outcome will be obtained as a result of the gait analysis
Double Support Phase
Time frame: Baseline
Double support phase during walking. This outcome will be obtained as a result of the gait analysis
1 secondary outcome
Stride Length
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Mar 2026.
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
Acute Ichemic Stroke
Recruiting
Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
Stroke, Upper Extremity Paresis
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Stroke, run by Ankara Yildirim Beyazıt University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Stance Phase (time frame: Baseline). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Mar 2026.