VapingNCT07116837
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
A study testing Vaping prevention video ads in people with Vaping, run by UNC Lineberger Comprehensive Cancer Center at 1 site in United States.
Trial summary
The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Read more about this study
- Who is it for?
- Ages 13 to 20 yearsHealthy volunteers can take part
- Conditions the study is for
- Vaping
- What is being tested?
- Vaping prevention video ads
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 3,113 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Oct 2025to 14 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 20 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Age 13-20 years old
- Current vaper (defined as using e-cigarettes in the past 30 days) or susceptible to vaping. Participants will be considered 'susceptible to vaping' if they answer anything other than "definitely not" to 3 screening items assessing their susceptibility to vaping. An example item is, "If one of your best friends were to offer you a vape, would you use it?" (Definitely not, probably not, probably yes, definitely yes).
- Live in the United States
Who cannot join
- Live outside of the United States
Trial locations and contacts
1 site in 1 country.
United States1 site
University of North Carolina, Chapel Hill
Chapel Hill, North Carolina, 27599
About this study
The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults aged 18-20 who live in the US and who are susceptible to vaping or who currently vape. In an online survey, participants will be randomized to view five randomly selected vaping prevention ads identified from a previous content analysis. After viewing the videos, participants will rate each video on the perceived message effectiveness scale and respond to questions about vaping appeal and urge to vape. The survey will take 15-20 minutes.
A follow-up survey of a subset of participants will be conducted around two weeks after they have been exposed to vaping prevention video ads in the baseline survey. Participants will view a total of six videos, including the five videos they watched previously, shown one at a time, along with one "decoy" video ad. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The survey will take 10-15 minutes.
Read the detailed description
Health communication campaigns are a scientific approach for preventing and reducing tobacco product use among adolescents. Although a growing number of studies have examined the effects of e-cigarette communication among young adults, there is only a modest number of published studies targeting adolescents. There is little information about the objective features of vaping prevention video ads. Additionally, the follow-up study will explore how ad features are associated with recognition.
Setting: This study is an online survey of adolescents and young adults (age 13-20) who are susceptible to vaping or who currently vape and live in the United States.
Recruitment and Informed Consent: Adolescent and young adult participants will be recruited by Qualtrics Services. Participants who are 18 to 20 years old and are eligible for the study will view a consent form as part of the survey and check a box to indicate that they agree to participate in the study. For minor participants, Qualtrics will recruit parents of 13-17-year-olds, so they will receive the survey invitation with the parental permission/consent form. From there, parents will be asked to pass the survey to their child. Once the participant has completed the consent/assent process, they will be able to begin the survey.
Procedures: up to 3,500 adolescents and young adults who are susceptible to vaping or currently vape will be randomized to view 5 randomly selected ads from a pool of vaping prevention video ads identified from previous study activities. Participants will be screened for susceptibility to vaping or current vape use. Participants will then answer questions on demographic information and tobacco product use. They will view 5 videos, 1 at a time ,randomly assigned from the larger pool of videos. After viewing the videos, participants will rate each video on perceived message effectiveness (primary outcome) and respond to questions about vaping appeal and urge to vape (secondary outcomes). Finally, participants will respond to standard questions on psychological distress, tobacco product use in the home, and general health-related questions. After the survey, participants will view a debrief page with information about tobacco use harms. The survey will take 15-20 minutes.
For the follow-up study, a subset of participants will be asked to complete another survey around two weeks after they have been exposed to vaping prevention video ads in the first survey. In this survey, participants will view a total of six videos, including the five videos they watched when taking the Aim 2 survey around two weeks earlier, shown one at a time, along with one "decoy" video ad. The order of the videos will be randomized. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The follow-up survey will take 10-15 minutes.
- Conditions
- Vaping
- Being tested
- Vaping prevention video ads
- Medical subject headings
- Vaping
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Vaping prevention video adsBehavioural
Participants will view and rate 5 vaping prevention video ads. The vaping prevention video ads cover a variety of different topics and were identified in a previous study activity.
| Study group | Role | What they receive |
|---|---|---|
| Vaping | Experimental | Adolescents and young adults who are susceptible to vaping or currently vape. Receives: Behavioral: Vaping prevention video ads |
What is being measured
The primary outcome is the main question the study is designed to answer.
Perceived Message Effectiveness
The 3-item perceived message effectiveness scale assesses the extent to which participants perceived the vaping prevention video ads as effective. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". The overall scale score is determined by averaging scores from the 3 items, with higher scores representing higher perceived message effectiveness. This is the primary outcome for the main study.
Measured: Baseline (Main study)
Recognition
This survey item assesses whether the participant remembers viewing the ad in the baseline survey 2 weeks prior. Response options are "Yes", "No", and "Not sure". The response will be dichotomized as 1 = "Yes" and 0 = "No"/"Not sure" for analyses. This is the primary outcome for the follow-up study.
Measured: Two-week Follow-up
Secondary outcomes (2)
Urge to vape
This survey item assesses the extent to which the video ad makes participants want to vape. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". A higher score represents a stronger urge to vape. This is a secondary outcome of the main study.
Measured: Baseline
Vaping appeal
This survey item assesses the extent to which the ad makes vaping seem appealing. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". A higher score represents higher vaping appeal. This is a secondary outcome of the main study.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Aug 2025
- Study start1 Oct 2025
- Primary completion14 Jun 2026
- Study completion14 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for VapingStudies of the same condition, open and under way.
- More trials run by UNC Lineberger Comprehensive Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 3,113 participants (actual)
Sponsor and investigators
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA), Food and Drug Administration (FDA)
- Responsible party
- Sponsor
- Investigators
- Sarah Kowitt, PhD, Principal investigator, UNC Lineberger Comprehensive Cancer CenterSeth Noar, PhD, Principal investigator, UNC Lineberger Comprehensive Cancer CenterYoujin Jang, PhD, Principal investigator, UNC Lineberger Comprehensive Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07116837
- Sponsor's protocol ID
- 24-2140
- Status last verified
- Jun 2026
- First submitted
- 7 Aug 2025
- Last updated
- 1 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
- ClinicalTrials.gov ID
- NCT07116837
- Acronym / sponsor ID
- 24-2140
- Conditions
- Vaping
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 3,113 participants (actual)
- Lead sponsor
- UNC Lineberger Comprehensive Cancer CenterUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA), Food and Drug Administration (FDA)
- Study start
- 1 Oct 2025 (actual)
- Primary completion
- 14 Jun 2026 (actual)
- Study completion
- 14 Jun 2026 (actual)
- First posted
- 12 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults aged 18-20 who live in the US and who are susceptible to vaping or who currently vape. In an online survey, participants will be randomized to view five randomly selected vaping prevention ads identified from a previous content analysis. After viewing the videos, participants will rate each video on the perceived message effectiveness scale and respond to questions about vaping appeal and urge to vape. The survey will take 15-20 minutes.
A follow-up survey of a subset of participants will be conducted around two weeks after they have been exposed to vaping prevention video ads in the baseline survey. Participants will view a total of six videos, including the five videos they watched previously, shown one at a time, along with one "decoy" video ad. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The survey will take 10-15 minutes.
Detailed description
Health communication campaigns are a scientific approach for preventing and reducing tobacco product use among adolescents. Although a growing number of studies have examined the effects of e-cigarette communication among young adults, there is only a modest number of published studies targeting adolescents. There is little information about the objective features of vaping prevention video ads. Additionally, the follow-up study will explore how ad features are associated with recognition.
Setting: This study is an online survey of adolescents and young adults (age 13-20) who are susceptible to vaping or who currently vape and live in the United States.
Recruitment and Informed Consent: Adolescent and young adult participants will be recruited by Qualtrics Services. Participants who are 18 to 20 years old and are eligible for the study will view a consent form as part of the survey and check a box to indicate that they agree to participate in the study. For minor participants, Qualtrics will recruit parents of 13-17-year-olds, so they will receive the survey invitation with the parental permission/consent form. From there, parents will be asked to pass the survey to their child. Once the participant has completed the consent/assent process, they will be able to begin the survey.
Procedures: up to 3,500 adolescents and young adults who are susceptible to vaping or currently vape will be randomized to view 5 randomly selected ads from a pool of vaping prevention video ads identified from previous study activities. Participants will be screened for susceptibility to vaping or current vape use. Participants will then answer questions on demographic information and tobacco product use. They will view 5 videos, 1 at a time ,randomly assigned from the larger pool of videos. After viewing the videos, participants will rate each video on perceived message effectiveness (primary outcome) and respond to questions about vaping appeal and urge to vape (secondary outcomes). Finally, participants will respond to standard questions on psychological distress, tobacco product use in the home, and general health-related questions. After the survey, participants will view a debrief page with information about tobacco use harms. The survey will take 15-20 minutes.
For the follow-up study, a subset of participants will be asked to complete another survey around two weeks after they have been exposed to vaping prevention video ads in the first survey. In this survey, participants will view a total of six videos, including the five videos they watched when taking the Aim 2 survey around two weeks earlier, shown one at a time, along with one "decoy" video ad. The order of the videos will be randomized. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The follow-up survey will take 10-15 minutes.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Vaping | Experimental | Behavioral: Vaping prevention video adsAdolescents and young adults who are susceptible to vaping or currently vape. |
Who may qualify
- Ages
- 13 to 20 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Age 13-20 years old
- Current vaper (defined as using e-cigarettes in the past 30 days) or susceptible to vaping. Participants will be considered 'susceptible to vaping' if they answer anything other than "definitely not" to 3 screening items assessing their susceptibility to vaping. An example item is, "If one of your best friends were to offer you a vape, would you use it?" (Definitely not, probably not, probably yes, definitely yes).
- Live in the United States
Key exclusion criteria (1 listed)
- Live outside of the United States
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Vaping prevention video adsParticipants will view and rate 5 vaping prevention video ads. The vaping prevention video ads cover a variety of different topics and were identified in a previous study activity. | Behavioural | Vaping |
Primary outcome
Perceived Message Effectiveness
Time frame: Baseline (Main study)
The 3-item perceived message effectiveness scale assesses the extent to which participants perceived the vaping prevention video ads as effective. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". The overall scale score is determined by averaging scores from the 3 items, with higher scores representing higher perceived message effectiveness. This is the primary outcome for the main study.
Recognition
Time frame: Two-week Follow-up
This survey item assesses whether the participant remembers viewing the ad in the baseline survey 2 weeks prior. Response options are "Yes", "No", and "Not sure". The response will be dichotomized as 1 = "Yes" and 0 = "No"/"Not sure" for analyses. This is the primary outcome for the follow-up study.
2 secondary outcomes
Urge to vape
Time frame: Baseline
Vaping appeal
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2026.
- UNC Lineberger Comprehensive Cancer Center Clinical TrialsLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sarah Kowitt, PhD principal investigator
UNC Lineberger Comprehensive Cancer Center
Seth Noar, PhD principal investigator
UNC Lineberger Comprehensive Cancer Center
Youjin Jang, PhD principal investigator
UNC Lineberger Comprehensive Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Vaping prevention video ads in people with Vaping, run by UNC Lineberger Comprehensive Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Perceived Message Effectiveness (time frame: Baseline (Main study)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2026.