DementiaNCT07119502
Implementation of a Minimal Equipment Exercise Intervention in Community-dwelling Older Adults With Dementia
A study testing Minimal-equipment progressive resistance training in people with Dementia, run by Geriatric Education and Research Institute.
Trial summary
The aim for this study is to investigate the effectiveness of a 16-week minimal-equipment progressive resistance training program compared to usual care, in improving functional outcomes among older adults with dementia in Singapore. Read more about this study
- Who is it for?
- Ages 55 years and older
- Conditions the study is for
- Dementia
- What is being tested?
- Minimal-equipment progressive resistance training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- Oct 2025to Mar 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 55 years or older
- Community-dwelling
- Formal medical diagnosis of dementia of any cause
Who cannot join
- Diagnosis of neurological and/or myopathic disorders
- Severe audio-visual impairment
- Severe mobility impairment that affects study participation
- Not suitable to participate in exercise intervention as deemed by a nursing staff or allied health professional
About this study
The aim for this study is to investigate the effectiveness of a 16-week minimal-equipment progressive resistance training program compared to usual care, in improving functional outcomes among older adults with dementia in Singapore.
Participants will:
- receive either minimal-equipment progressive resistance training or continue with usual care
- perform physical and cognitive function tests at three time-points
- Conditions
- Dementia
- Being tested
- Minimal-equipment progressive resistance training
- Keywords
- Dementia, Resistance training, Exercise
- Medical subject headings
- Dementia, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Minimal-equipment progressive resistance trainingOther
The intervention consists of resistance training exercises that target major upper and lower body muscle groups with the use of portable equipment such as resistance bands and wrist/ankle weights. The exercise dosage will be progressively increased across the 16 weeks to achieve training adaptations. The exercise programme will be conducted three times per week, with each session lasting approximately 30 to 45 minutes.
| Study group | Role | What they receive |
|---|---|---|
| Progressive resistance training | Experimental | Participants in the intervention arm will receive a 16-week progressive resistance training programme implemented by center staff in a community dementia daycare center. Receives: Other: Minimal-equipment progressive resistance training |
| Usual Care | No intervention | Participants in the control arm will continue receiving the usual care provided at the community dementia daycare center. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in handgrip strength
This test is a measurement of upper limb strength. Handgrip strength will be measured in kilograms using a Jamar Plus + Digital Hand Dynamometer. Participants will squeeze the dynamometer with maximum effort in a seated position with their arms at their sides and elbows flexed at 90 degrees. Two trials will be administered for each arm and the highest of four readings will be used for analysis.
Measured: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
Change in five times sit-to-stand test
This test is a measurement of lower limb strength. Participants will be instructed to perform five chair stands as fast as possible using a chair without arms, and the time recorded will be used for analysis.
Measured: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
Change in 30-seconds sit-to-stand test
This test is a measurement of lower limb strength and power. Participants will be instructed to perform repeated chair stands as fast as possible using a chair without arms, and number of completed full stands will be recorded for analysis.
Measured: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
Secondary outcomes (10)
Change in Time Up and Go test
This test is a measurement of functional mobility. The test measures the time taken for participants to rise from a seated position, walk three metres at a comfortable speed, make a turn, walk back, and return to a seated position. Two trials will be administered, and the mean reading will be used for analysis.
Measured: Baseline, Post-intervention (Week 17)
Change in Short Physical Performance Battery test
This test is a measurement of physical function that consists of three components inclusive of 4-metre gait speed test, five times sit-to-stand test and a progressive test of standing balance.
Measured: Baseline, Post-intervention (Week 17)
Change in gait speed test
The test measures the time taken for participants to walk six metres at a normal pace from a moving start without deceleration. Two trials will be administered, and the mean reading will be used for analysis.
Measured: Baseline, Post-intervention (Week 17)
Change in functional reach test
This test is a measurement of dynamic balance. While standing with their back to the wall, participants are instructed to reach forward with their dominant arm outstretched at shoulder level while maintaining a fixed stance. The distance between the metacarpal bone of the third finger in the initial position and the maximum point reached is measured. Two trials will be administered, and the better reading will be used for analysis.
Measured: Baseline, Post-intervention (Week 17)
Change in calf circumference
This test is a surrogate measurement of muscle mass. The calf circumference is determined by the maximum value of both calves measured using a nonelastic tape.
Measured: Baseline, Post-intervention (Week 17)
Change in mid-upper-arm circumference
This test is a surrogate measurement of muscle mass. The mid-upper-arm circumference is measured at the mid-point between the acromial surface of the scapula and the olecranon process of the elbow over the dominant arm when bent at 90 degrees using a nonelastic tape.
Measured: Baseline, Post-intervention (Week 17)
Change in Mini-Mental State Examination
The Mini-Mental State Examination (MMSE) is a measure of global cognitive function. Participants will respond to a brief questionnaire of 11 items. The score ranges between 0 and 30. Higher scores indicate better cognitive function.
Measured: Baseline, Post-intervention (Week 17)
Change in Trail Making Test
This is a test of cogntive function. Participants will be instructed to connect numbered and lettered circles in ascending order as quickly as possible. Time to complete the test will be recorded for analysis.
Measured: Baseline, Post-intervention (Week 17)
Change in EQ-5D-5L proxy index score
This test is a measurement of health-related quality of life. The score ranges from -0.59 to 1 and is computed based on five dimensions with higher scores indicating better quality if life. A center staff will act as a proxy assessor on behalf of the participant.
Measured: Baseline, Post-intervention (Week 17)
Fall incidence
Number of falls sustained during intervention period.
Measured: Post-intervention (Week 17)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Aug 2025
- Study startOct 2025 (estimated)
- Primary completionMar 2026 (estimated)
- Study completionMar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DementiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- Quasi-experimental
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Geriatric Education and Research Institute
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Tou Nien Xiang, Geriatric Education and Research Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07119502
- Sponsor's protocol ID
- GERI1640
- Status last verified
- Aug 2025
- First submitted
- 5 Aug 2025
- Last updated
- 13 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Anonymised individual participant data will be shared along with future research publications or reports with description of all data variables.
Study at a glance
From the registry record, last updated by the sponsor on 13 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Implementation of a Minimal Equipment Exercise Intervention in Community-dwelling Older Adults With Dementia
- ClinicalTrials.gov ID
- NCT07119502
- Acronym / sponsor ID
- GERI1640
- Conditions
- Dementia
- Keywords
- Dementia, Resistance training, Exercise
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Geriatric Education and Research InstituteOther government
- Study start
- Oct 2025 (estimated)
- Primary completion
- Mar 2026 (estimated)
- Study completion
- Mar 2026 (estimated)
- First posted
- 13 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim for this study is to investigate the effectiveness of a 16-week minimal-equipment progressive resistance training program compared to usual care, in improving functional outcomes among older adults with dementia in Singapore.
Participants will:
- receive either minimal-equipment progressive resistance training or continue with usual care
- perform physical and cognitive function tests at three time-points
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Quasi-experimental
| Arm | Type | Receives |
|---|---|---|
| Progressive resistance training | Experimental | Other: Minimal-equipment progressive resistance trainingParticipants in the intervention arm will receive a 16-week progressive resistance training programme implemented by center staff in a community dementia daycare center. |
| Usual Care | No intervention | –Participants in the control arm will continue receiving the usual care provided at the community dementia daycare center. |
Who may qualify
- Ages
- 55 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Aged 55 years or older
- Community-dwelling
- Formal medical diagnosis of dementia of any cause
Key exclusion criteria (4 listed)
- Diagnosis of neurological and/or myopathic disorders
- Severe audio-visual impairment
- Severe mobility impairment that affects study participation
- Not suitable to participate in exercise intervention as deemed by a nursing staff or allied health professional
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Minimal-equipment progressive resistance trainingThe intervention consists of resistance training exercises that target major upper and lower body muscle groups with the use of portable equipment such as resistance bands and wrist/ankle weights. The exercise dosage will be progressively increased across the 16 weeks to achieve training adaptations. The exercise programme will be conducted three times per week, with each session lasting approximately 30 to 45 minutes. | Other | Progressive resistance training |
Primary outcome
Change in handgrip strength
Time frame: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
This test is a measurement of upper limb strength. Handgrip strength will be measured in kilograms using a Jamar Plus + Digital Hand Dynamometer. Participants will squeeze the dynamometer with maximum effort in a seated position with their arms at their sides and elbows flexed at 90 degrees. Two trials will be administered for each arm and the highest of four readings will be used for analysis.
Change in five times sit-to-stand test
Time frame: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
This test is a measurement of lower limb strength. Participants will be instructed to perform five chair stands as fast as possible using a chair without arms, and the time recorded will be used for analysis.
Change in 30-seconds sit-to-stand test
Time frame: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)
This test is a measurement of lower limb strength and power. Participants will be instructed to perform repeated chair stands as fast as possible using a chair without arms, and number of completed full stands will be recorded for analysis.
10 secondary outcomes
Change in Time Up and Go test
Time frame: Baseline, Post-intervention (Week 17)
Change in Short Physical Performance Battery test
Time frame: Baseline, Post-intervention (Week 17)
Change in gait speed test
Time frame: Baseline, Post-intervention (Week 17)
Change in functional reach test
Time frame: Baseline, Post-intervention (Week 17)
Change in calf circumference
Time frame: Baseline, Post-intervention (Week 17)
Change in mid-upper-arm circumference
Time frame: Baseline, Post-intervention (Week 17)
Change in Mini-Mental State Examination
Time frame: Baseline, Post-intervention (Week 17)
Change in Trail Making Test
Time frame: Baseline, Post-intervention (Week 17)
Change in EQ-5D-5L proxy index score
Time frame: Baseline, Post-intervention (Week 17)
Fall incidence
Time frame: Post-intervention (Week 17)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Aug 2025.
- Individual participant dataSharing planned: Yes. Anonymised individual participant data will be shared along with future research publications or reports with description of all data variables.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Minimal-equipment progressive resistance training in people with Dementia, run by Geriatric Education and Research Institute.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in handgrip strength (time frame: Baseline, Mid-intervention (Week 9), Post-intervention (Week 17)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Aug 2025.