Suicide PreventionHOPAIRNCT07119671
Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.
A study testing HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit in people with Suicide Prevention, run by Hôpital le Vinatier at 1 site in France.
Trial summary
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap . Hospitalization offers a crucial opportunity for life-preserving intervention . Brief health interventions and contacts are reputed to be easy to implement, effective and inexpensive . Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Suicide Prevention
- What is being tested?
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 siteFrance
- Study dates
- 24 Sep 2025to 15 Oct 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Major ;
- Hospitalized in a psychiatric crisis unit;
- Having attempted suicide in the month preceding hospitalisation;
- Able to give free and informed consent;
- Having given consent;
- French-speaking person with at least B1 level (reading and writing);
- With access to the technical resources required for the study;
- With a postal address.
Who cannot join
- Presenting a relational modality incompatible with the proposed intervention (agitation, acute delirium, major cognitive disorders or psychic disorganisation, etc.);
- Included in another research protocol related to suicide prevention.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Hospitalier Le Vinatier
Bron, AURA, 69678 CEDEX
POULET EMMANUEL, PUPH, 0033437915120, emmanuel.poulet@chu-lyon.fr
VIAL VERONIQUE, 0033437915531, veronique.vial@ch-le-vinatier.fr
About this study
Official title: Peer-Aid and Hope Box: A Feasibility Study of a Combined Intervention for Suicidal Patients Hospitalized in a Psychiatric Crisis Unit
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap .
Hospitalization offers a crucial opportunity for life-preserving intervention . Brief health interventions and contacts are reputed to be easy to implement, effective and inexpensive .
Read more
The Hope Box is a practical emotional management tool that aims to encourage the expression of reasons for living by materializing them in a customizable box, filled with objects, photos, writings and memories in order to find comfort and hope .
Peer support use their experiential knowledge of disorders and recovery to accompany people and help humanize care . They can play a decisive role in suicide prevention .
In contrast to an approach focusing only on risk factors, peer support and the Hope Box are both focus on protective factors, the strengths of the people concerned and hope.
The primary objective of this study is to evaluate the feasibility of the HOPAIR intervention (peer-support and Hope Box, completed by a reminder postcard) with suicidal people hospitalized in psychiatric crisis units. Its secondary objective is to assess the potential effectiveness on intensity of hopelessness, sense of self-efficacy, reasons for living, perceived social support and suicidal recurrence at 3 months.
This is a mixed-methods study involving 40 patients and 2 peer support in two crisis hospitalization units.
Read the detailed description
Around 703,000 people die by suicide each year worldwide, with suicide prevention being a national priority in France since 2014. The period after a patient is discharged from the hospital is a particularly high-risk time for suicide, especially for those with a history of suicide attempts.
This study proposes a new intervention called HOPAIR, which combines three key components:
- Peer support: A professional peer-helper, who has personal experience with mental health challenges, meets with the patient to share their recovery story and foster a sense of hope and connection.
- The Hope Box: A personalized box that patients fill with objects, photos, and memories to engage their five senses and serve as a tool for emotional management, comfort, and distraction during times of distress.
- A reminder postcard: Sent one month after the initial intervention to reinforce the key concepts of the Hope Box and maintain motivation.
The primary objective of the HOPAIR study is to evaluate the feasibility of this combined intervention for suicidal patients hospitalized in a psychiatric crisis unit. The study also aims to assess the potential effectiveness of HOPAIR on several factors after three months, including:
- Feelings of hopelessness and self-efficacy
- Reasons for living
- Perceived social support
- The presence of suicidal thoughts and repeat suicide attempts The study is a mixed-methods, bi-centric research project that will recruit patients 24-48 hours after admission. The intervention will take place within two to four days of admission, followed by the postcard mailing one month later, and a final evaluation at three months. This evaluation will include re-administering scales to measure the study's objectives and conducting qualitative interviews with a subset of participants to assess their satisfaction with the program.
- Conditions
- Suicide Prevention
- Being tested
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Keywords
- Suicide prevention, Hope box, Pair aid
- Medical subject headings
- Suicide Prevention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis UnitOther
This intervention begins with an initial discussion focused on the individual's lived experience, followed by an explanation of the Hope Box's principle, utility, and use. After each intervention, the peer supporter will complete a satisfaction self-questionnaire to provide feedback.
| Study group | Role | What they receive |
|---|---|---|
| HOPAIR Intervention: Meeting between Peer helper and Concerned Individual in Psychiatric Crisis Unit | Other | This intervention begins with an initial discussion focused on the individual's lived experience, followed by an explanation of the Hope Box's principle, utility, and use. After each intervention, the peer supporter will complete a satisfaction self-questionnaire to provide feedback. Receives: Other: HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility Evaluation of the Combined HOPAIR Intervention (Peer Support, Hope Box, and Postcard Reminder) for Suicidal Inpatients in Psychiatric Crisis Units at 3-Month Post-Intervention.
It will be assessed by :
- Achievement of the target of recruiting two peer support (yes/no).
- Completion of training by the two peer support (yes/no).
- Recruitment capacity of 40 patients, 20 in each center;
- Collection and description of the characteristics of the resulting sample at the time of inclusion by the IPA within 24 hours of arrival in the department;
- The acceptability of the intervention and the use of the Hope Box through feedback from the people concerned by means of a semi-directive telephone interview at 3 months by the IPA;
- Feedback from peer support after each intervention, using self-questionnaires;
Measured: 37 months
Secondary outcomes (2)
Effectiveness of the HOPAIR intervention on indicators of well-being at 3 months post-intervention.
The potential effectiveness of the HOPAIR system will be assessed by comparing the differences in scores and responses to questions at inclusion, during a face-to-face interview and at 3 months after the HOPAIR intervention during a telephone interview by the IPA using the following scales and questions.
Measured: 37 months
Effectiveness of the HOPAIR intervention on indicators of suicidality at 3 months post-intervention.
The potential effectiveness of the HOPAIR system will be assessed by comparing the differences in scores and responses to questions at inclusion, during a face-to-face interview and at 3 months after the HOPAIR intervention during a telephone interview by the IPA using the following scales and questions
Measured: 37 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Aug 2025
- Study start24 Sep 2025
- Primary completion15 Oct 2028 (estimated)
- Study completion15 Oct 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Suicide PreventionStudies of the same condition, open and under way.
- More trials run by Hôpital le VinatierThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Mixed bi-centric
- Masking
- None (open label)
- Enrolment
- 42 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hôpital le Vinatier
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Tamara VERNET, IPA, Principal investigator, Centre Hospitalier le Vinatier
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07119671
- Sponsor's protocol ID
- 2025-A00082-47
- Acronym
- HOPAIR
- Status last verified
- Oct 2025
- First submitted
- 29 Jul 2025
- Last updated
- 21 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Peer-Aid and Hope Box: A Feasibility Study of a Combined Intervention for Suicidal Patients Hospitalized in a Psychiatric Crisis Unit
- ClinicalTrials.gov ID
- NCT07119671
- Acronym / sponsor ID
- HOPAIR / 2025-A00082-47
- Conditions
- Suicide Prevention
- Keywords
- Suicide prevention, Hope box, Pair aid
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 42 participants (estimated)
- Lead sponsor
- Hôpital le VinatierUniversity, hospital or other
- Study start
- 24 Sep 2025 (actual)
- Primary completion
- 15 Oct 2028 (estimated)
- Study completion
- 15 Oct 2029 (estimated)
- First posted
- 13 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap .
Hospitalization offers a crucial opportunity for life-preserving intervention . Brief health interventions and contacts are reputed to be easy to implement, effective and inexpensive .
The Hope Box is a practical emotional management tool that aims to encourage the expression of reasons for living by materializing them in a customizable box, filled with objects, photos, writings and memories in order to find comfort and hope .
Peer support use their experiential knowledge of disorders and recovery to accompany people and help humanize care . They can play a decisive role in suicide prevention .
In contrast to an approach focusing only on risk factors, peer support and the Hope Box are both focus on protective factors, the strengths of the people concerned and hope.
The primary objective of this study is to evaluate the feasibility of the HOPAIR intervention (peer-support and Hope Box, completed by a reminder postcard) with suicidal people hospitalized in psychiatric crisis units. Its secondary objective is to assess the potential effectiveness on intensity of hopelessness, sense of self-efficacy, reasons for living, perceived social support and suicidal recurrence at 3 months.
This is a mixed-methods study involving 40 patients and 2 peer support in two crisis hospitalization units.
Detailed description
Around 703,000 people die by suicide each year worldwide, with suicide prevention being a national priority in France since 2014. The period after a patient is discharged from the hospital is a particularly high-risk time for suicide, especially for those with a history of suicide attempts.
This study proposes a new intervention called HOPAIR, which combines three key components:
- Peer support: A professional peer-helper, who has personal experience with mental health challenges, meets with the patient to share their recovery story and foster a sense of hope and connection.
- The Hope Box: A personalized box that patients fill with objects, photos, and memories to engage their five senses and serve as a tool for emotional management, comfort, and distraction during times of distress.
- A reminder postcard: Sent one month after the initial intervention to reinforce the key concepts of the Hope Box and maintain motivation.
The primary objective of the HOPAIR study is to evaluate the feasibility of this combined intervention for suicidal patients hospitalized in a psychiatric crisis unit. The study also aims to assess the potential effectiveness of HOPAIR on several factors after three months, including:
- Feelings of hopelessness and self-efficacy
- Reasons for living
- Perceived social support
- The presence of suicidal thoughts and repeat suicide attempts The study is a mixed-methods, bi-centric research project that will recruit patients 24-48 hours after admission. The intervention will take place within two to four days of admission, followed by the postcard mailing one month later, and a final evaluation at three months. This evaluation will include re-administering scales to measure the study's objectives and conducting qualitative interviews with a subset of participants to assess their satisfaction with the program.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Mixed bi-centric
| Arm | Type | Receives |
|---|---|---|
| HOPAIR Intervention: Meeting between Peer helper and Concerned Individual in Psychiatric Crisis Unit | Other | Other: HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis UnitThis intervention begins with an initial discussion focused on the individual's lived experience, followed by an explanation of the Hope Box's principle, utility, and use. After each intervention, the peer supporter will complete a satisfaction self-questionnaire to provide feedback. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Major ;
- Hospitalized in a psychiatric crisis unit;
- Having attempted suicide in the month preceding hospitalisation;
- Able to give free and informed consent;
- Having given consent;
Key exclusion criteria (2 listed)
- Presenting a relational modality incompatible with the proposed intervention (agitation, acute delirium, major cognitive disorders or psychic disorganisation, etc.);
- Included in another research protocol related to suicide prevention.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis UnitThis intervention begins with an initial discussion focused on the individual's lived experience, followed by an explanation of the Hope Box's principle, utility, and use. After each intervention, the peer supporter will complete a satisfaction self-questionnaire to provide feedback. | Other | HOPAIR Intervention: Meeting between Peer helper and Concerned Individual in Psychiatric Crisis Unit |
Primary outcome
Feasibility Evaluation of the Combined HOPAIR Intervention (Peer Support, Hope Box, and Postcard Reminder) for Suicidal Inpatients in Psychiatric Crisis Units at 3-Month Post-Intervention.
Time frame: 37 months
It will be assessed by : * Achievement of the target of recruiting two peer support (yes/no). * Completion of training by the two peer support (yes/no). * Recruitment capacity of 40 patients, 20 in each center; * Collection and description of the characteristics of the resulting sample at the time of inclusion by the IPA within 24 hours of arrival in the department; * The acceptability of the intervention and the use of the Hope Box through feedback from the people concerned by means of a semi-directive telephone interview at 3 months by the IPA; * Feedback from peer support after each intervention, using self-questionnaires;
2 secondary outcomes
Effectiveness of the HOPAIR intervention on indicators of well-being at 3 months post-intervention.
Time frame: 37 months
Effectiveness of the HOPAIR intervention on indicators of suicidality at 3 months post-intervention.
Time frame: 37 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Tamara VERNET, IPA principal investigator
Centre Hospitalier le Vinatier
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit in people with Suicide Prevention, run by Hôpital le Vinatier at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Tamara VERNET, IPA (00334 37 91 52 10, Tamara.vernet@ch-le-vinatier.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility Evaluation of the Combined HOPAIR Intervention (Peer Support, Hope Box, and Postcard Reminder) for Suicidal Inpatients in Psychiatric Crisis Units at 3-Month Post-Intervention. (time frame: 37 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Apr 2026.