Skin AgingNCT07120542
Menopausal Impact on Skin Aging Among Egyptian Women
An observational study of Skin Aging, run by Sohag University.
Trial summary
The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60. The main question the study wants to answer is: Does menopause cause any changes in how the skin ages? To find out, the participants will be divided into two groups based on their menstrual… Read more about this study
- Who is it for?
- Ages 40 to 60 years, women only
- Conditions the study is for
- Skin Aging
- What is being tested?
- Dermoscopy
- Type of treatment
- Medical device
- How many people
- 500 participants
- Where
- No sites listed yet
- Study dates
- 1 Nov 2025to Nov 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- Women only
- Adult
Study population: This study will include Egyptian women between the ages of 40 and 60 years who are either premenopausal or postmenopausal, based on their menstrual history. participants must be in good general health and not currently receiving hormone replacement therapy or any treatment known to affect skin condition.
Who may be able to join
- Females aged 40 to 60 years
- Egyptian nationality or residency
- Ability to provide informed consent
- Classified as either:
- Premenopausal (still menstruating regularly)
- Postmenopausal (no menstruation for ≥12 months)
Who cannot join
- Menopausal transition (Perimenopausal women
- Menopause induced by hysterectomy
- History of hormone therapy in the past 6 months
- Active dermatological conditions affecting the face (e.g. eczema, psoriasis)
- Use of anti-aging skin treatments (e.g. laser, fillers, retinoids)
- Severe chronic illnesses that may affect skin condition
About this study
Official title: Menopausal Impact on Skin Aging Among Egyptian Women: a Comparative Cross-sectional Study
The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60.
The main question the study wants to answer is:
Does menopause cause any changes in how the skin ages?
To find out, the participants will be divided into two groups based on their menstrual history:
- Women who have not yet gone through menopause (premenopausal)
- Women who have already gone through menopause (postmenopausal) A researcher will examine the skin of women in both groups to look for signs of aging. Then, the results will be compared to see if there are any differences between the two groups.
- Conditions
- Skin Aging
- Being tested
- Dermoscopy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
DermoscopyDevice
dermoscopic assessment of skin aging signs
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinical skin aging severity using Glogau Photoaging Scale
The Glogau Photoaging Scale will be used for evaluation. Facial assessment will be conducted both at rest and during facial animation to observe dynamic changes. Participant will be categorized into 4 types or grades where type 1 is mild skin aging and type 4 is severe skin aging
Measured: Assessed once at baseline during participant's visit
Dermoscopic skin aging score using the dermoscopic photoaging assessment scale
this scale is used to assess facial skin aging. The face will be divided into four regions: the forehead, right cheek, left cheek, and chin. Each region will be examined for the presence of the following features: yellowish discoloration, yellow papules, white linear areas indicating skin atrophy, lentigines, hypo- or hyperpigmented macules, telangiectasia, actinic keratoses, senile comedones, deep wrinkles, superficial wrinkles, and criss-cross wrinkles. Scoring follows a binary (yes/no) approach, where the presence of a given feature in any of the four regions scores one point, yielding a total possible score ranging from 0 to 44. a higher score means worse outcome.
Measured: Assessed once at baseline during participant 's visit
Secondary outcomes (3)
Prevalence of specific clinical and dermoscopic aging features
Measured: Recorded during clinical and dermoscopic assessment at baseline
Correlation between menopausal status and severity of skin aging
Measured: Assessed once at baseline during participant's visit based on menopausal history and skin aging scores
Correlation between menopausal duration and skin aging
Measured: Menopausal duration collected via history at baseline; skin aging assessed at baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Aug 2025
- Study start1 Nov 2025 (estimated)
- Primary completionNov 2026 (estimated)
- Study completionNov 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin AgingStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Amal Abdulhameed Mostafa, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07120542
- Sponsor's protocol ID
- Soh-Med--25-7-1MS
- Status last verified
- Aug 2025
- First submitted
- 23 Jul 2025
- Last updated
- 13 Aug 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 13 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Menopausal Impact on Skin Aging Among Egyptian Women: a Comparative Cross-sectional Study
- ClinicalTrials.gov ID
- NCT07120542
- Acronym / sponsor ID
- Soh-Med--25-7-1MS
- Conditions
- Skin Aging
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 1 Nov 2025 (estimated)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Nov 2027 (estimated)
- First posted
- 13 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60.
The main question the study wants to answer is:
Does menopause cause any changes in how the skin ages?
To find out, the participants will be divided into two groups based on their menstrual history:
- Women who have not yet gone through menopause (premenopausal)
- Women who have already gone through menopause (postmenopausal) A researcher will examine the skin of women in both groups to look for signs of aging. Then, the results will be compared to see if there are any differences between the two groups.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 40 to 60 years
- Sex
- Female only
- Age groups
- Adult
- Study population
- This study will include Egyptian women between the ages of 40 and 60 years who are either premenopausal or postmenopausal, based on their menstrual history. participants must be in good general health and not currently receiving hormone replacement therapy or any treatment known to affect skin condition.
Key inclusion criteria (6 listed)
- Females aged 40 to 60 years
- Egyptian nationality or residency
- Ability to provide informed consent
- Classified as either:
Key exclusion criteria (6 listed)
- Menopausal transition (Perimenopausal women
- Menopause induced by hysterectomy
- History of hormone therapy in the past 6 months
- Active dermatological conditions affecting the face (e.g. eczema, psoriasis)
- Use of anti-aging skin treatments (e.g. laser, fillers, retinoids)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dermoscopydermoscopic assessment of skin aging signs | Device | – |
Primary outcome
Clinical skin aging severity using Glogau Photoaging Scale
Time frame: Assessed once at baseline during participant's visit
The Glogau Photoaging Scale will be used for evaluation. Facial assessment will be conducted both at rest and during facial animation to observe dynamic changes. Participant will be categorized into 4 types or grades where type 1 is mild skin aging and type 4 is severe skin aging
Dermoscopic skin aging score using the dermoscopic photoaging assessment scale
Time frame: Assessed once at baseline during participant 's visit
this scale is used to assess facial skin aging. The face will be divided into four regions: the forehead, right cheek, left cheek, and chin. Each region will be examined for the presence of the following features: yellowish discoloration, yellow papules, white linear areas indicating skin atrophy, lentigines, hypo- or hyperpigmented macules, telangiectasia, actinic keratoses, senile comedones, deep wrinkles, superficial wrinkles, and criss-cross wrinkles. Scoring follows a binary (yes/no) approach, where the presence of a given feature in any of the four regions scores one point, yielding a total possible score ranging from 0 to 44. a higher score means worse outcome.
3 secondary outcomes
Prevalence of specific clinical and dermoscopic aging features
Time frame: Recorded during clinical and dermoscopic assessment at baseline
Correlation between menopausal status and severity of skin aging
Time frame: Assessed once at baseline during participant's visit based on menopausal history and skin aging scores
Correlation between menopausal duration and skin aging
Time frame: Menopausal duration collected via history at baseline; skin aging assessed at baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Aug 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Skin Aging, run by Sohag University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinical skin aging severity using Glogau Photoaging Scale (time frame: Assessed once at baseline during participant's visit). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Aug 2025.