Obsessive-Compulsive Disorder (OCD)NCT07124780
Helping Adults With Obsessive-Compulsive Disorder Succeed at Work
A study testing Individual Placement and Support (IPS) and Standard Vocational Services in people with Obsessive-Compulsive Disorder (OCD), run by New York State Psychiatric Institute at 1 site in United States.
Trial summary
The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. All 40 participants will receive up to 12 sessions of the first-line treatment for OCD called exposure and response prevention, a form of… Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Obsessive-Compulsive Disorder (OCD)
- What is being tested?
- Individual Placement and Support (IPS) and Standard Vocational Services
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 12 May 2026to Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Currently unemployed and interested in finding competitive employment in New York State
- Currently residing in New York State
- Primary diagnosis of OCD
- For those currently on psychiatric medication: On a stable dose of psychiatric medication (for at least 6 weeks) and willing to remain on this dose for the first three months of CBT.
- Access to the internet through a mobile device or computer
Who cannot join
- In the process of applying for or currently receiving disability benefits
- Currently receiving supported employment services
- Active suicidality or recent suicide attempt
- Active substance use problem (other than nicotine) that warrants treatment
- Comorbid psychiatric conditions that significantly elevate the risk of study participation such as psychotic disorders or bipolar disorder
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
The New York State Psychiatric Institute
New York, New York, 10032
Sapana Patel, PhD, 646-774-8491, sapana.patel@nyspi.columbia.edu
Blair Simpson, MD PhD, 646-774-8110, blair.simpson@nyspi.columbia.edu
About this study
The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. All 40 participants will receive up to 12 sessions of the first-line treatment for OCD called exposure and response prevention, a form of Cognitive Behavioral Therapy (CBT). Assigned by chance, half of the people will also receive Individual Placement and Support (IPS); the other half will receive standard vocational services (SVS). This study will compare these two approaches for helping adults with OCD find and maintain work.
Read the detailed description
The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. In a randomized controlled trial (RCT), we will compare the work and clinical outcomes of individuals with OCD (n=20) who receive CBT plus standard vocational services (SVS) to those who receive this same course of CBT but who also receive Individual Placement and Support (IPS) (n=20). Work and clinical outcomes will be measured before starting CBT, at the end of CBT treatment, and at 6, 9, and 12-month time points.
- Conditions
- Obsessive-Compulsive Disorder (OCD)
- Being tested
- Individual Placement and Support (IPS), Standard Vocational Services
- Keywords
- supported employment, obsessive-compulsive disorder
- Medical subject headings
- Obsessive-Compulsive Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Individual Placement and Support (IPS)Behavioural
Also called IPS
Individual Placement and Support is an evidence-based model of supported employment for individuals with mental illness. In IPS, participants will meet with an IPS specialist weekly who will help the study participant create resumes, conduct job searches online or in the community, complete job applications, role-play interviews, and, if requested, accompany them when visiting prospective employers.
Standard Vocational ServicesBehavioural
Also called SVS
In Standard Vocational Services, participants will meet with a representative from the American Jobs Center (AJC) who will help them find a job by identifying their interests, assess their skills and abilities, and advise them on in-demand jobs and potential training opportunities.
| Study group | Role | What they receive |
|---|---|---|
| Standard Vocational Services plus Cognitive Behavioral Therapy for OCD | Active comparator | Standard vocational services includes support in finding employment with support from the American Jobs Center over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months. Receives: Behavioral: Standard Vocational Services |
| Individual Placement and Support plus Cognitive Behavior Therapy for OCD | Experimental | Individual Placement and Support includes support in finding employment with support from an IPS employment specialist over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months. Receives: Behavioral: Individual Placement and Support (IPS) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Competitive employment
Employed at least one work shift in an integrated work setting in the open job market at prevailing wages with supervision provided by personnel employed by the business.
Measured: From enrollment to the end of 12 months
Hours worked
Total hours of competitive employment
Measured: From enrollment to the end of 12 months
Secondary outcomes (2)
Yale-Brown Obsessive Compulsive Scale (scores range from 0-40 with higher scores indicating greater OCD severity)
Change in severity of OCD symptoms
Measured: From enrollment to the end of 12 months
Quality of Life Enjoyment and Satisfaction Scale (scores range from 14-70 with higher scores indicating greater life satisfaction and enjoyment)
Change in degree of enjoyment and satisfaction experienced by subjects in various areas of daily functioning
Measured: From enrollment to the end of 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Aug 2025
- Study start12 May 2026
- Primary completionAug 2027 (estimated)
- Study completionAug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obsessive-Compulsive Disorder (OCD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- New York State Psychiatric Institute
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sapana Patel, New York State Psychiatric Institute
- Investigators
- Sapana R Patel, Ph.D., Principal investigator, The New York State Psychiatric InstituteBlair Simpson, MD, Ph.D., Principal investigator, The New York State Psychiatric Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07124780
- Sponsor's protocol ID
- NYSPI2025-79
- Other IDs
- 90IFRE0091
- Status last verified
- Jul 2026
- First submitted
- 4 Aug 2025
- Last updated
- 31 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Helping Adults With Obsessive-Compulsive Disorder Succeed at Work
- ClinicalTrials.gov ID
- NCT07124780
- Acronym / sponsor ID
- NYSPI2025-79
- Conditions
- Obsessive-Compulsive Disorder (OCD)
- Keywords
- supported employment, obsessive-compulsive disorder
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- New York State Psychiatric InstituteUniversity, hospital or other
- Study start
- 12 May 2026 (actual)
- Primary completion
- Aug 2027 (estimated)
- Study completion
- Aug 2027 (estimated)
- First posted
- 15 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. All 40 participants will receive up to 12 sessions of the first-line treatment for OCD called exposure and response prevention, a form of Cognitive Behavioral Therapy (CBT). Assigned by chance, half of the people will also receive Individual Placement and Support (IPS); the other half will receive standard vocational services (SVS). This study will compare these two approaches for helping adults with OCD find and maintain work.
Detailed description
The purpose of this study is to compare two models of employment services for people with obsessive-compulsive disorder (OCD) interested in finding and maintaining employment. In a randomized controlled trial (RCT), we will compare the work and clinical outcomes of individuals with OCD (n=20) who receive CBT plus standard vocational services (SVS) to those who receive this same course of CBT but who also receive Individual Placement and Support (IPS) (n=20). Work and clinical outcomes will be measured before starting CBT, at the end of CBT treatment, and at 6, 9, and 12-month time points.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Standard Vocational Services plus Cognitive Behavioral Therapy for OCD | Active comparator | Behavioral: Standard Vocational ServicesStandard vocational services includes support in finding employment with support from the American Jobs Center over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months. |
| Individual Placement and Support plus Cognitive Behavior Therapy for OCD | Experimental | Behavioral: Individual Placement and Support (IPS)Individual Placement and Support includes support in finding employment with support from an IPS employment specialist over 12 months. Cognitive Behavior Therapy for OCD consists of a standard course of exposure and response prevention over 12 weeks, followed by monthly maintenance sessions for 12 months. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Currently unemployed and interested in finding competitive employment in New York State
- Currently residing in New York State
- Primary diagnosis of OCD
- For those currently on psychiatric medication: On a stable dose of psychiatric medication (for at least 6 weeks) and willing to remain on this dose for the first three months of CBT.
- Access to the internet through a mobile device or computer
Key exclusion criteria (5 listed)
- In the process of applying for or currently receiving disability benefits
- Currently receiving supported employment services
- Active suicidality or recent suicide attempt
- Active substance use problem (other than nicotine) that warrants treatment
- Comorbid psychiatric conditions that significantly elevate the risk of study participation such as psychotic disorders or bipolar disorder
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Individual Placement and Support (IPS)Also: IPSIndividual Placement and Support is an evidence-based model of supported employment for individuals with mental illness. In IPS, participants will meet with an IPS specialist weekly who will help the study participant create resumes, conduct job searches online or in the community, complete job applications, role-play interviews, and, if requested, accompany them when visiting prospective employers. | Behavioural | Individual Placement and Support plus Cognitive Behavior Therapy for OCD |
| Standard Vocational ServicesAlso: SVSIn Standard Vocational Services, participants will meet with a representative from the American Jobs Center (AJC) who will help them find a job by identifying their interests, assess their skills and abilities, and advise them on in-demand jobs and potential training opportunities. | Behavioural | Standard Vocational Services plus Cognitive Behavioral Therapy for OCD |
Primary outcome
Competitive employment
Time frame: From enrollment to the end of 12 months
Employed at least one work shift in an integrated work setting in the open job market at prevailing wages with supervision provided by personnel employed by the business.
Hours worked
Time frame: From enrollment to the end of 12 months
Total hours of competitive employment
2 secondary outcomes
Yale-Brown Obsessive Compulsive Scale (scores range from 0-40 with higher scores indicating greater OCD severity)
Time frame: From enrollment to the end of 12 months
Quality of Life Enjoyment and Satisfaction Scale (scores range from 14-70 with higher scores indicating greater life satisfaction and enjoyment)
Time frame: From enrollment to the end of 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
- Link to study abstract on National Rehabilitation Information CenterLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sapana R Patel, Ph.D. principal investigator
The New York State Psychiatric Institute
Blair Simpson, MD, Ph.D. principal investigator
The New York State Psychiatric Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Individual Placement and Support (IPS) and Standard Vocational Services in people with Obsessive-Compulsive Disorder (OCD), run by New York State Psychiatric Institute at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sapana R. Patel, Ph.D. (646-774-8491, sapana.patel@nyspi.columbia.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Competitive employment (time frame: From enrollment to the end of 12 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.