SutureNCT07127029
Effect of Petrolatum Coating on Fast-absorbing Gut Suture
A study testing Petrolatum coating of fast-absorbing gut suture in people with Suture and Suture Dermatologic, run by San Antonio Uniformed Services Health Education Consortium.
Trial summary
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Suture, Suture Dermatologic, Mohs Micrographic Surgery
- What is being tested?
- Petrolatum coating of fast-absorbing gut suture
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 14 participants
- Where
- No sites listed yet
- Study dates
- 26 Jan 2016to 14 Oct 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Healthy volunteers within department of Dermatology
- Able to receive care within the host facility (Dept of Defense)
Who cannot join
- current or planned pregnancy
- Allergy to lidocaine
- Infection on the shoulder site
About this study
Official title: Effect Of Petrolatum On Absorption of Fast Gut Suture In Vivo
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques, Dermatology, Closure Technique
- Being tested
- Petrolatum coating of fast-absorbing gut suture
- Keywords
- Petrolatum, Absorbable Suture, Gut Suture, Fast-absorbing Gut Suture, Wound Closure, Suture Coating
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Petrolatum coating of fast-absorbing gut sutureDevice
Also called petrolatum coating
6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid
| Study group | Role | What they receive |
|---|---|---|
| 6-0 Fast-Absorbing Gut Suture | Experimental | Two 6-0 fast-absorbing gut sutures were placed in the skin of deltoid, randomized to site A/B for the control (uncoated) and intervention (petrolatum coated) suture. Receives: Device: Petrolatum coating of fast-absorbing gut suture |
What is being measured
The primary outcome is the main question the study is designed to answer.
Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture.
Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture.
Measured: Postprocedurally daily until suture is degraded (less than 2 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2025
- Study start26 Jan 2016
- Primary completion14 Oct 2016
- Study completion14 Oct 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for SutureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- San Antonio Uniformed Services Health Education Consortium
- Sponsor type
- US federal agency
- Responsible party
- Principal investigator, Jason Susong, San Antonio Uniformed Services Health Education Consortium
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07127029
- Sponsor's protocol ID
- FWH20160040H
- Status last verified
- Aug 2025
- First submitted
- 8 Aug 2025
- Last updated
- 17 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Susong JR, Neiner JR. Effect of petrolatum coating on fast-absorbing gut suture. J Am Acad Dermatol. 2018 Nov;79(5):952-953. doi: 10.1016/j.jaad.2018.04.041. Epub 2018 Apr 30. No abstract available.
PubMed 29723559
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect Of Petrolatum On Absorption of Fast Gut Suture In Vivo
- ClinicalTrials.gov ID
- NCT07127029
- Acronym / sponsor ID
- FWH20160040H
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques, Dermatology, Closure Technique
- Keywords
- Petrolatum, Absorbable Suture, Gut Suture, Fast-absorbing Gut Suture, Wound Closure, Suture Coating
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- San Antonio Uniformed Services Health Education ConsortiumUS federal agency
- Study start
- 26 Jan 2016 (actual)
- Primary completion
- 14 Oct 2016 (actual)
- Study completion
- 14 Oct 2016 (actual)
- First posted
- 17 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- Single blind (participant)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| 6-0 Fast-Absorbing Gut Suture | Experimental | Device: Petrolatum coating of fast-absorbing gut sutureTwo 6-0 fast-absorbing gut sutures were placed in the skin of deltoid, randomized to site A/B for the control (uncoated) and intervention (petrolatum coated) suture. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Healthy volunteers within department of Dermatology
- Able to receive care within the host facility (Dept of Defense)
Key exclusion criteria (3 listed)
- current or planned pregnancy
- Allergy to lidocaine
- Infection on the shoulder site
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Petrolatum coating of fast-absorbing gut sutureAlso: petrolatum coating6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid | Device | 6-0 Fast-Absorbing Gut Suture |
Primary outcome
Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture.
Time frame: Postprocedurally daily until suture is degraded (less than 2 weeks)
Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2025.
- Results publication: PubMed 29723559Susong JR, Neiner JR. Effect of petrolatum coating on fast-absorbing gut suture. J Am Acad Dermatol. 2018 Nov;79(5):952-953. doi: 10.1016/j.jaad.2018.04.041. Epub 2018 Apr 30. No abstract available.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Petrolatum coating of fast-absorbing gut suture in people with Suture and Suture Dermatologic, run by San Antonio Uniformed Services Health Education Consortium.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture. (time frame: Postprocedurally daily until suture is degraded (less than 2 weeks)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07127029, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2025.