StokeNCT07127367
Treating New Learning and Memory Deficits Following Stroke
A study testing Memory Training in people with Stoke, run by Kessler Foundation at 1 site in United States.
Trial summary
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons following stroke Read more about this study
- Who is it for?
- Ages 60 years and older
- Conditions the study is for
- Stoke
- What is being tested?
- Memory Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 5 Jan 2026to Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Stroke over 1 year ago
- Memory challenges
Who cannot join
- Aphasia
- non English speaking
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Kessler Foundation
East Hanover, New Jersey, 07936
Nancy Moore, MA, 973.324.8450, nbmoore@kesslerfoundation.org
About this study
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons following stroke
- Conditions
- Stoke
- Being tested
- Memory Training
- Keywords
- Memory, Learning, Stroke
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Memory TrainingBehavioural
Memory retraining exercises will be administered on a laptop computer twice a week for five weeks (10 training sessions).
| Study group | Role | What they receive |
|---|---|---|
| KFmSMT | Experimental | Memory training on computer, 2 times per week for 5 weeks Receives: Behavioral: Memory Training |
| Memory program | Sham comparator | Memory training on computer, 2 times per week for 5 weeks Receives: Behavioral: Memory Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
CVLT-III
16 words from 4 semantic categories presented over 5 learning trials. Includes Free and cued immediate and delayed recall and delayed recognition
Measured: baseline, week 7 and 6 months following intervention.
modified Ecological Memory Simulations (EMS)
Everyday memory simulations, recalling a story or directions from a doctor
Measured: Baseline, week 7, and 6 months following intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2025
- Study start5 Jan 2026
- Primary completionOct 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for StokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Kessler Foundation
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nancy Chiaravalloti, Kessler Foundation
- Investigators
- Nancy Chiaravalloti, PhD, Principal investigator, Kessler Foundation
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07127367
- Sponsor's protocol ID
- E-1301-25
- Status last verified
- Jun 2026
- First submitted
- 11 Aug 2025
- Last updated
- 8 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Berg I, Koning-Haanstra M, Deelman B. Long-term effects of memory rehabilitation: A controlled study. Neuropsychol Rehabil. 1(2):97-111.
Gross AL, Rebok GW. Memory training and strategy use in older adults: results from the ACTIVE study. Psychol Aging. 2011 Sep;26(3):503-17. doi: 10.1037/a0022687.
PubMed 21443356
Study at a glance
From the registry record, last updated by the sponsor on 8 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Treating New Learning and Memory Deficits Following Stroke
- ClinicalTrials.gov ID
- NCT07127367
- Acronym / sponsor ID
- E-1301-25
- Conditions
- Stoke
- Keywords
- Memory, Learning, Stroke
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Kessler FoundationUniversity, hospital or other
- Study start
- 5 Jan 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Oct 2026 (estimated)
- First posted
- 17 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons following stroke
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| KFmSMT | Experimental | Behavioral: Memory TrainingMemory training on computer, 2 times per week for 5 weeks |
| Memory program | Sham comparator | Behavioral: Memory TrainingMemory training on computer, 2 times per week for 5 weeks |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Stroke over 1 year ago
- Memory challenges
Key exclusion criteria (2 listed)
- Aphasia
- non English speaking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Memory TrainingMemory retraining exercises will be administered on a laptop computer twice a week for five weeks (10 training sessions). | Behavioural | KFmSMT, Memory program |
Primary outcome
CVLT-III
Time frame: baseline, week 7 and 6 months following intervention.
16 words from 4 semantic categories presented over 5 learning trials. Includes Free and cued immediate and delayed recall and delayed recognition
modified Ecological Memory Simulations (EMS)
Time frame: Baseline, week 7, and 6 months following intervention
Everyday memory simulations, recalling a story or directions from a doctor
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Sep 2026.
- BackgroundBerg I, Koning-Haanstra M, Deelman B. Long-term effects of memory rehabilitation: A controlled study. Neuropsychol Rehabil. 1(2):97-111.
- Background: PubMed 21443356Gross AL, Rebok GW. Memory training and strategy use in older adults: results from the ACTIVE study. Psychol Aging. 2011 Sep;26(3):503-17. doi: 10.1037/a0022687.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nancy Chiaravalloti, PhD principal investigator
Kessler Foundation
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Memory Training in people with Stoke, run by Kessler Foundation at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 8 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nancy Moore, M.A. (19733248450, nbmoore@kesslerfoundation.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
CVLT-III (time frame: baseline, week 7 and 6 months following intervention.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07127367, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Sep 2026; AzTrials last refreshed its copy on 28 Oct 2026.