Mild Cognitive ImpairmentNCT07130591
Efficiency of CogniPlat on Cognitive Functions in Older Adults
A study testing Cogniplat game platform in people with Mild Cognitive Impairment, run by Izmir Democracy University at 1 site in Turkey (Türkiye).
Trial summary
Mild cognitive impairment is a common intermediate stage between normal aging and dementia, affecting memory and other cognitive domains in older adults. While pharmacologic treatments lack strong evidence, exercise, cognitive training, and game-based interventions have shown positive effects on cognitive functions. Read more about this study
- Who is it for?
- Ages 65 to 78 yearsHealthy volunteers can take part
- Conditions the study is for
- Mild Cognitive Impairment
- What is being tested?
- Cogniplat game platform
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jan 2023to 15 Nov 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 78 years
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- To volunteer to participate in the study
- To be over 65 years old
- had a mini-mental test score above 24
- could use smartphones and tablets
- To have sufficient reading and writing skills to use the gaming platform
- To have good cooperation skills and not have a disease causing vision loss
Who cannot join
- Individuals with orthopedic or neurological conditions that prevent the use of a tablet with the upper extremities
- Individuals who are unable to maintain sitting balance
- Individuals with hearing loss that may prevent them from hearing information related to the gaming platform
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Investigation of the Efficiency of the Cogniplat Gaming Platform on Cognitive Functions in Geriatric Individuals: a Randomized Controlled Trial
Mild cognitive impairment is a common intermediate stage between normal aging and dementia, affecting memory and other cognitive domains in older adults. While pharmacologic treatments lack strong evidence, exercise, cognitive training, and game-based interventions have shown positive effects on cognitive functions. The Cogniplat gaming platform, designed to improve cognitive abilities through personalized, multidisciplinary game exercises, has not yet been clinically evaluated. The present study aims to assess the effectiveness of Cogniplat in enhancing cognitive functions in geriatric individuals.
Read the detailed description
Mild cognitive impairment may occur with physiological aging in geriatric individuals. This describes an intermediate stage from normal cognitive status to dementia. In mild cognitive impairment, there is cognitive impairment in both memory and non-memory domains. Anxiety, depression and other adverse mental health conditions also lead to decreased cognitive functioning. The risk of mild cognitive impairment turning into dementia is quite high. Therefore, diagnosis, follow-up and treatment are important issues. Mild cognitive impairment is common in geriatric populations. Its prevalence increases with age and low education level. The incidence of mild cognitive impairment in geriatric individuals aged 65 years and older is 15-20%.
There is no high quality evidence showing the efficacy of pharmacologic agents in the treatment of mild cognitive impairment. There are also studies showing that exercise and cognitive training have an improving effect on cognitive functions. Cognitive games also have a stimulating effect on memory and communication in these individuals. Game-based education reduces the risk of mild cognitive impairment and depression by stimulating the cerebral cortex and also motivates older adults to participate in treatment. Computer-based cognitive gaming training has been found to have positive effects on attention ability and memory development in this population.
The Cogniplat game platform used in the study is a rehabilitation tool developed to improve the cognitive functions of elderly individuals. Cogniplat is based on a multidisciplinary approach combining theories from neuropsychology, cognitive linguistics and speech therapy. It focuses on improving cognitive functions through different game exercises. In addition, Cogniplat automatically adjusts the difficulty and type of exercises by detecting the cognitive needs of individuals. In the literature, the Cogniplat game platform has been developed, but no studies evaluating its effectiveness have been found. Therefore, the present study was planned to examine the effect of the "Cogniplat" game platform on cognitive functions in geriatric individuals.
- Conditions
- Mild Cognitive Impairment
- Being tested
- Cogniplat game platform, Control group
- Keywords
- cogniplat, geriatric rehabilitation, cognitive games
- Medical subject headings
- Cognitive Dysfunction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cogniplat game platformOther
Also called CGP
The Cogniplat gaming platform is designed to improve cognitive function in geriatric individuals, with or without mild cognitive impairment. Participants played the Cogniplat games face-to-face with a physiotherapist twice a week on non-consecutive days for 10 weeks, sessions lasting about 30-45 minutes. Scores from the platform were recorded to evaluate progress.
Control groupOther
Also called CG
Individuals in this group did not participate in any regular play program. Demographic data were recorded. For evaluation purposes, a single session of Cogniplat game platform was applied in the first interview and in the second interview 10 weeks later. Initial and final evaluations were recorded.
| Study group | Role | What they receive |
|---|---|---|
| Play Group | Experimental | Group of patients treated with the Cogniplat gaming platform Receives: Other: Cogniplat game platform |
| Control Group | Other | Individuals in this group did not participate in any regular play program Receives: Other: Control group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mini-Mental Test
The Mini-Mental Test consists of eleven items under five main headings: orientation, recording memory, attention and calculation, recall and language, and is evaluated on a total of 30 points. A score of 23/24 is accepted as the threshold for the diagnosis of mild dementia in Turkish elderly
Measured: At baseline and 10 week after
Game Platform Scoring
For each game played on the platform, game duration, accuracy and speed variables were recorded on the servers connected to the platform. Individuals in both the study and control groups played a game on the platform, and the score of this game was recorded on the system and used in the analysis.Game duration, accuracy and speed will be aggregated into a single game performance score automatically generated by the platform and recorded for analysis
Measured: At baseline and 10 week after
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Aug 2025
- Study start15 Jan 2023
- Primary completion15 May 2023
- Study completion15 Nov 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mild Cognitive ImpairmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This prospective, randomized controlled study
- Masking
- None (open label)
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Izmir Democracy University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ferruh Taşpınar, Izmir Democracy University
- Investigators
- Betül Taspinar, Prof.Dr., Principal investigator, Izmir Democracy UniversityAyşe Sezgi Kızılırmak Karataş, Pt.PhD, Principal investigator, Izmir Democracy UniversityNuri Üçler, Msc.Pt., Principal investigator, Ege UniversityEbru Köse, Pt.PhD, Principal investigator, Izmir Democracy UniversityCansu Ozdemir, Msc.Pt, Principal investigator, Izmir Democracy University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07130591
- Sponsor's protocol ID
- cogniplat
- Status last verified
- Aug 2025
- First submitted
- 12 Aug 2025
- Last updated
- 26 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Efficiency of the Cogniplat Gaming Platform on Cognitive Functions in Geriatric Individuals: a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07130591
- Acronym / sponsor ID
- cogniplat
- Conditions
- Mild Cognitive Impairment
- Keywords
- cogniplat, geriatric rehabilitation, cognitive games
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Izmir Democracy UniversityUniversity, hospital or other
- Study start
- 15 Jan 2023 (actual)
- Primary completion
- 15 May 2023 (actual)
- Study completion
- 15 Nov 2023 (actual)
- First posted
- 19 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mild cognitive impairment is a common intermediate stage between normal aging and dementia, affecting memory and other cognitive domains in older adults. While pharmacologic treatments lack strong evidence, exercise, cognitive training, and game-based interventions have shown positive effects on cognitive functions. The Cogniplat gaming platform, designed to improve cognitive abilities through personalized, multidisciplinary game exercises, has not yet been clinically evaluated. The present study aims to assess the effectiveness of Cogniplat in enhancing cognitive functions in geriatric individuals.
Detailed description
Mild cognitive impairment may occur with physiological aging in geriatric individuals. This describes an intermediate stage from normal cognitive status to dementia. In mild cognitive impairment, there is cognitive impairment in both memory and non-memory domains. Anxiety, depression and other adverse mental health conditions also lead to decreased cognitive functioning. The risk of mild cognitive impairment turning into dementia is quite high. Therefore, diagnosis, follow-up and treatment are important issues. Mild cognitive impairment is common in geriatric populations. Its prevalence increases with age and low education level. The incidence of mild cognitive impairment in geriatric individuals aged 65 years and older is 15-20%.
There is no high quality evidence showing the efficacy of pharmacologic agents in the treatment of mild cognitive impairment. There are also studies showing that exercise and cognitive training have an improving effect on cognitive functions. Cognitive games also have a stimulating effect on memory and communication in these individuals. Game-based education reduces the risk of mild cognitive impairment and depression by stimulating the cerebral cortex and also motivates older adults to participate in treatment. Computer-based cognitive gaming training has been found to have positive effects on attention ability and memory development in this population.
The Cogniplat game platform used in the study is a rehabilitation tool developed to improve the cognitive functions of elderly individuals. Cogniplat is based on a multidisciplinary approach combining theories from neuropsychology, cognitive linguistics and speech therapy. It focuses on improving cognitive functions through different game exercises. In addition, Cogniplat automatically adjusts the difficulty and type of exercises by detecting the cognitive needs of individuals. In the literature, the Cogniplat game platform has been developed, but no studies evaluating its effectiveness have been found. Therefore, the present study was planned to examine the effect of the "Cogniplat" game platform on cognitive functions in geriatric individuals.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- This prospective, randomized controlled study
| Arm | Type | Receives |
|---|---|---|
| Play Group | Experimental | Other: Cogniplat game platformGroup of patients treated with the Cogniplat gaming platform |
| Control Group | Other | Other: Control groupIndividuals in this group did not participate in any regular play program |
Who may qualify
- Ages
- 65 to 78 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (6 listed)
- To volunteer to participate in the study
- To be over 65 years old
- had a mini-mental test score above 24
- could use smartphones and tablets
- To have sufficient reading and writing skills to use the gaming platform
Key exclusion criteria (3 listed)
- Individuals with orthopedic or neurological conditions that prevent the use of a tablet with the upper extremities
- Individuals who are unable to maintain sitting balance
- Individuals with hearing loss that may prevent them from hearing information related to the gaming platform
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cogniplat game platformAlso: CGPThe Cogniplat gaming platform is designed to improve cognitive function in geriatric individuals, with or without mild cognitive impairment. Participants played the Cogniplat games face-to-face with a physiotherapist twice a week on non-consecutive days for 10 weeks, sessions lasting about 30-45 minutes. Scores from the platform were recorded to evaluate progress. | Other | Play Group |
| Control groupAlso: CGIndividuals in this group did not participate in any regular play program. Demographic data were recorded. For evaluation purposes, a single session of Cogniplat game platform was applied in the first interview and in the second interview 10 weeks later. Initial and final evaluations were recorded. | Other | Control Group |
Primary outcome
Mini-Mental Test
Time frame: At baseline and 10 week after
The Mini-Mental Test consists of eleven items under five main headings: orientation, recording memory, attention and calculation, recall and language, and is evaluated on a total of 30 points. A score of 23/24 is accepted as the threshold for the diagnosis of mild dementia in Turkish elderly
Game Platform Scoring
Time frame: At baseline and 10 week after
For each game played on the platform, game duration, accuracy and speed variables were recorded on the servers connected to the platform. Individuals in both the study and control groups played a game on the platform, and the score of this game was recorded on the system and used in the analysis.Game duration, accuracy and speed will be aggregated into a single game performance score automatically generated by the platform and recorded for analysis
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Betül Taspinar, Prof.Dr. principal investigator
Izmir Democracy University
Ayşe Sezgi Kızılırmak Karataş, Pt.PhD principal investigator
Izmir Democracy University
Nuri Üçler, Msc.Pt. principal investigator
Ege University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cogniplat game platform in people with Mild Cognitive Impairment, run by Izmir Democracy University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mini-Mental Test (time frame: At baseline and 10 week after). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2025.