AutismNCT07134569
Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
A study testing VR-based motor training in people with Autism, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle… Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Autism
- What is being tested?
- VR-based motor training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteTaiwan
- Study dates
- 15 Dec 2023to 31 Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- young adult aged between 18 and 45 years who had a diagnosis of ASD from a licensed mental health or medical professional based on DSM-5.
- was motivated to complete the 6-week VR-based motor function training.
- had a full-scale IQ > 70 on the WAIS-IV.
- young adult aged between 18 and 45 years who do not have a diagnosis of ASD.
- had a full-scale IQ > 70 on the WAIS-IV.
Who cannot join
- a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury) that hamper walking function, or neurosurgery.
- visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
- The Non-ASD control group
- a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury), or neurosurgery that hamper walking function.
- visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
National Taiwan University Hospital
Taipei
Yi Ling Chien, Clinical Professor, +886 2312 3456 ext. 266013, ntuh.peers@gmail.com
About this study
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle strength, balance, and motor control. The main questions aim to answer are:
[primary hypothesis or outcome measure 1]? [primary hypothesis or outcome measure 2]? If there is a comparison group: Researchers will compare [arm information] to see if [insert effects].
Participants will [describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items].
- Conditions
- Autism
- Being tested
- VR-based motor training
- Keywords
- Virtual Reality, motor training
- Medical subject headings
- Autistic Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
VR-based motor trainingBehavioural
Six weeks, twice per week.
| Study group | Role | What they receive |
|---|---|---|
| Autism | Experimental | Not described Receives: Behavioral: VR-based motor training |
| Typically developing control | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
The performance of movement operational assessment
Participants will take movement operational assessment, which composed of different tests, such as Timed Up and Go Test (TUG), the 10-meter walk test (10MWT) and the 6-minute walk test (6WMT)
Measured: 40 minutes
The performance of motor coordination control
the performance recorded with Vicon, an motion capture system, and Single Leg Stance Test
Measured: 1 hour, twice
Secondary outcomes (4)
The N-back Task performance
Measured: 40 minutes
The performance of Timed Up and Go Test (TUG)
Measured: 1 minute, twice
The performance of the 10-meter walk test (10MWT)
Measured: 1 minute, twice
The performance of 6-minute walk test (6WMT)
Measured: 6 minutes, twice
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Aug 2025
- Study start15 Dec 2023
- Primary completion31 Jul 2027 (estimated)
- Study completion31 Jul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AutismStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07134569
- Sponsor's protocol ID
- 202311005RINC
- Status last verified
- Dec 2025
- First submitted
- 4 Feb 2025
- Last updated
- 12 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
- ClinicalTrials.gov ID
- NCT07134569
- Acronym / sponsor ID
- 202311005RINC
- Conditions
- Autism
- Keywords
- Virtual Reality, motor training
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 15 Dec 2023 (actual)
- Primary completion
- 31 Jul 2027 (estimated)
- Study completion
- 31 Jul 2027 (estimated)
- First posted
- 21 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle strength, balance, and motor control. The main questions aim to answer are:
[primary hypothesis or outcome measure 1]? [primary hypothesis or outcome measure 2]? If there is a comparison group: Researchers will compare [arm information] to see if [insert effects].
Participants will [describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items].
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Autism | Experimental | Behavioral: VR-based motor training |
| Typically developing control | No intervention | – |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- young adult aged between 18 and 45 years who had a diagnosis of ASD from a licensed mental health or medical professional based on DSM-5.
- was motivated to complete the 6-week VR-based motor function training.
- had a full-scale IQ > 70 on the WAIS-IV.
- young adult aged between 18 and 45 years who do not have a diagnosis of ASD.
- had a full-scale IQ > 70 on the WAIS-IV.
Key exclusion criteria (5 listed)
- a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury) that hamper walking function, or neurosurgery.
- visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
- a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury), or neurosurgery that hamper walking function.
- visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| VR-based motor trainingSix weeks, twice per week. | Behavioural | Autism |
Primary outcome
The performance of movement operational assessment
Time frame: 40 minutes
Participants will take movement operational assessment, which composed of different tests, such as Timed Up and Go Test (TUG), the 10-meter walk test (10MWT) and the 6-minute walk test (6WMT)
The performance of motor coordination control
Time frame: 1 hour, twice
the performance recorded with Vicon, an motion capture system, and Single Leg Stance Test
4 secondary outcomes
The N-back Task performance
Time frame: 40 minutes
The performance of Timed Up and Go Test (TUG)
Time frame: 1 minute, twice
The performance of the 10-meter walk test (10MWT)
Time frame: 1 minute, twice
The performance of 6-minute walk test (6WMT)
Time frame: 6 minutes, twice
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing VR-based motor training in people with Autism, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 12 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yi Ling Chien, Clinical Professor (+886 2-23123456 ext. 266013, ntuh.peers@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The performance of movement operational assessment (time frame: 40 minutes). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jan 2026.