Caregiving for CancerRAISENCT07139769
Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer
A study testing Psychosocial Intervention for Parental Caregivers of AYA with Cancer in people with Caregiving for Cancer, run by Zeba Ahmad, Ph.D. at 1 site in United States.
Trial summary
The study team aims to adapt a psychosocial intervention to reduce psychological distress among the caregiving parents of adolescents and young adults (aged 15-39) who have cancer. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Caregiving for Cancer
- What is being tested?
- Psychosocial Intervention for Parental Caregivers of AYA with Cancer
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 48 participants
- Where
- 1 siteUnited States
- Study dates
- Sep 2026to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Self-identifying parent/guardian who provides a primary informal caregiving role in their child's cancer
- Recipient of caregiving is aged between 15 and 39 years and is receiving treatment for cancer at the Mass General Brigham Cancer
- Participant must score equal to or greater than 2 (out of a possible 10) on the National Comprehensive Cancer Network Distress Thermometer
- English-speaking
- Aged over 18 years
Who cannot join
- -Active symptoms of psychosis or suicidal ideation that would preclude safe participation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Mass General Brigham Cancer Institute at Massachusetts General Hospital
Boston, Massachusetts, 02114
Zeba Ahmad, Ph.D., 631-786-0403, zahmad7@gmail.com
Zeba N Ahmad, Ph.D.
About this study
Official title: The RAISE Study: Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer
The study team aims to adapt a psychosocial intervention to reduce psychological distress among the caregiving parents of adolescents and young adults (aged 15-39) who have cancer. First, the study team will adapt an evidence-supported, group-based program for improving psychological resiliency (Stress Management and Resiliency Training - Relaxation Response Resiliency Program; SMART-3RP (E. R. Park et al., 2021)), and iteratively incorporate feedback from parents of AYAs with cancer using a mixed-methods approach. Next, the study team will pilot the refined intervention to assess for preliminary indicators of feasibility, acceptability, and potential for efficacy in reducing parental distress.
- Conditions
- Caregiving for Cancer
- Being tested
- Psychosocial Intervention for Parental Caregivers of AYA with Cancer
- Keywords
- adolescents and young adults with cancer, cancer caregivers
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Psychosocial Intervention for Parental Caregivers of AYA with CancerBehavioural
A new adaptation of an evidence-supported intervention, the SMART-3RP program, to address psychological symptoms and promote well-being among parental caregivers of AYA with cancer.
| Study group | Role | What they receive |
|---|---|---|
| Psychosocial Intervention for Parental Caregivers of AYA with Cancer-open pilot study | Experimental | The study team aims to evaluate the feasibility and acceptability of the adapted psychosocial intervention to 1) improve psychological resiliency to stress and 2) reduce symptoms of depression, anxiety, and post-traumatic stress among parental caregivers, through a single-arm open pilot trial of 32 parents. Receives: Behavioral: Psychosocial Intervention for Parental Caregivers of AYA with Cancer |
What is being measured
The primary outcome is the main question the study is designed to answer.
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Intervention Feasibility: Proportion of Participants Completing the Program
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Intervention Acceptability
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Measured: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Aug 2025
- Study startSep 2026 (estimated)
- Primary completionDec 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Caregiving for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 48 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Zeba Ahmad, Ph.D.
- Sponsor type
- University, hospital or other
- Collaborators
- American Cancer Society, Inc.
- Responsible party
- Sponsor-investigator, Zeba Ahmad, Ph.D., Massachusetts General Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07139769
- Sponsor's protocol ID
- 25-242
- Other IDs
- IRG-21-130-10-IRG-11
- Acronym
- RAISE
- Status last verified
- Aug 2026
- First submitted
- 18 Aug 2025
- Last updated
- 25 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The RAISE Study: Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer
- ClinicalTrials.gov ID
- NCT07139769
- Acronym / sponsor ID
- RAISE / 25-242
- Conditions
- Caregiving for Cancer
- Keywords
- adolescents and young adults with cancer, cancer caregivers
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 48 participants (estimated)
- Lead sponsor
- Zeba Ahmad, Ph.D.University, hospital or other
- Collaborators
- American Cancer Society, Inc.
- Study start
- Sep 2026 (estimated)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 24 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study team aims to adapt a psychosocial intervention to reduce psychological distress among the caregiving parents of adolescents and young adults (aged 15-39) who have cancer. First, the study team will adapt an evidence-supported, group-based program for improving psychological resiliency (Stress Management and Resiliency Training - Relaxation Response Resiliency Program; SMART-3RP (E. R. Park et al., 2021)), and iteratively incorporate feedback from parents of AYAs with cancer using a mixed-methods approach. Next, the study team will pilot the refined intervention to assess for preliminary indicators of feasibility, acceptability, and potential for efficacy in reducing parental distress.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Psychosocial Intervention for Parental Caregivers of AYA with Cancer-open pilot study | Experimental | Behavioral: Psychosocial Intervention for Parental Caregivers of AYA with CancerThe study team aims to evaluate the feasibility and acceptability of the adapted psychosocial intervention to 1) improve psychological resiliency to stress and 2) reduce symptoms of depression, anxiety, and post-traumatic stress among parental caregivers, through a single-arm open pilot trial of 32 parents. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Self-identifying parent/guardian who provides a primary informal caregiving role in their child's cancer
- Recipient of caregiving is aged between 15 and 39 years and is receiving treatment for cancer at the Mass General Brigham Cancer
- Participant must score equal to or greater than 2 (out of a possible 10) on the National Comprehensive Cancer Network Distress Thermometer
- English-speaking
- Aged over 18 years
Key exclusion criteria (1 listed)
- -Active symptoms of psychosis or suicidal ideation that would preclude safe participation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Psychosocial Intervention for Parental Caregivers of AYA with CancerA new adaptation of an evidence-supported intervention, the SMART-3RP program, to address psychological symptoms and promote well-being among parental caregivers of AYA with cancer. | Behavioural | Psychosocial Intervention for Parental Caregivers of AYA with Cancer-open pilot study |
Primary outcome
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
Intervention Feasibility: Proportion of Participants Completing the Program
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
Intervention Acceptability
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Aug 2026.
- Individual participant dataSharing planned: No
Related trials for Caregiving for Cancer
Active, not recruiting
Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
Breast Cancer, Lung Cancer
Active, not recruiting
Internet-based Support for Informal Caregivers of Patients With Head and Neck Cancer - Carer eSupport
Head and Neck Cancer
Not yet recruiting
The FamilyStrong Pilot Randomized Trial
Family Caregivers, Distress in Caregivers of Cancer Patients
Active, not recruiting
Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients
Glioma
Recruiting
Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer
Non-Small Cell Lung Cancer, Advanced Lung Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Psychosocial Intervention for Parental Caregivers of AYA with Cancer in people with Caregiving for Cancer, run by Zeba Ahmad, Ph.D. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Zeba N Ahmad, Ph.D. (16177241586, zahmad2@mgh.harvard.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll (time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Aug 2026.